• 한국수정란이식학회:학술대회논문집
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• 한국수정란이식학회 2005년도 제5회 발생공학 국제심포지엄 및 학술대회
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• pp.64-65
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• 2005

• 대한임상독성학회지
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• 제4권2호
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• pp.180-186
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• 2006

The various species of aconitum contain diterpene (C-20) and norditerpene (C-19) forms of the natural alkaloid aconitine that cause neurologic, gastrointestinal, cardiovascular symptoms. In chinese medicine, these plants has been used as drugs to treat pain, dyspepsia, cerebrovascular disease, and so on. Because the therapeutic window is narrow, poisoning may occur from unintentional exposure, with a variety of toxic effects such as arrhythmia, hypotension, paresthesia, paralysis, nausea, vomiting, and abdominal pain. Aconitine-containing folk remedies are widely used in Korea. We encountered two cases of ventricular arrhythmia in patients who ingested tablets, known as 'Wha-Pung-Dan' made with aconitine extracts and were subsequently admitted to the ED. A 42 year-old man who took 35 tablets presented with ventricualr tarchycardia, and 40 year-old woman who took 40 tablets showed premature ventricular contractions. Both patients were discharged normally without any complications after three days.

• Journal of Plant Biotechnology
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• 제36권3호
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• pp.224-229
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• 2009

Human lactoferrin is an iron-binding glycoprotein with many biological activities, including the protection against microbial and virus infection and stimulation of the immune system. We introduced a human lactoferrin (hLf) cDNA under the control of 35S promoter into sweet potato by particle bombardment. Transgenic plants were regenerated via somatic embryogenesis. Transgenic plants were produced typical tuberous roots in soil. PCR, Southern and northern analyses confirmed that the hLf cDNA was incorporated into the plant genome and was properly expressed in plants. Western blot analysis showed that the 80 kDa full length hLf protein was produced in transgenic tuberous roots. Overall results indicated that sweet potato would be an excellent host to produce human therapeutic proteins.

• 응용통계연구
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• 제23권2호
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• pp.249-261
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• 2010

Long-term forecasting of seasonal time series is critical in many applications such as planning business strategies and resolving possible problems of a business company. Unlike the traditional approach that depends solely on dynamic models, Li and Hinich (2002) introduced a combination of stochastic dynamic modeling with filter bank approach for forecasting seasonal patterns using highly coherent(High-C) waveforms. We modify the filter selection and forecasting procedure on wavelet domain to be more feasible and compare the resulting predictor with one that obtained from the wavelet variance estimation method. An improvement over other seasonal pattern extraction and forecasting methods based on such as wavelet scalogram, Holt-Winters, and seasonal autoregressive integrated moving average(SARIMA) is shown in terms of the prediction error. The performance of the proposed method is illustrated by a simulation study and an application to the real stock price data.

• Journal of the Korean Wood Science and Technology
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• 제42권2호
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• pp.214-221
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• 2014

The deterioration in wood by the brown-rot fungus (Fomitopsispalustris) and the white-rot fungus (Trametesversicolor) were measured using ultrasonic velocity. Those were used for the decay exposure and 4 wood species of wood as the test specimens, Pinusdensiflora, Larixkaempferi, Pinuskoraiensis and Pinusrigida, were chosen with both the brown- and white-rot culture petridish during 12 weeks. After 12 weeks, the decrease rate of ultrasonic velocity was measured at 10~15%. In both brown- and white-rot exposure experiments, P. rigida showed significant decrease in ultrasonic velocity (20%), L. kaempferi on the other hand did not show decrease in ultrasonic velocity. After the fungal exposure experiment, the inside of specimens was investigated by computer tomography (C/T). After C/T investigation, bending tests were performed.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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• pp.198-198
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• 2001

No report has been addressed to the CYP isoforms catalyzing chlorpropamide, a structural analogue of tolbutamide. To evaluate enzyme(s) mediating formation of 2-hydroxycWorpropamide, a major metabolite and identified by LC/Mass and NMR, incubation studies using human liver microsomes and cDNA expressed CYP were performed on the presence or absence of selective inhibitors of each CYP isoform. (omitted)

• 설비공학논문집
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• 제13권10호
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• pp.1017-1024
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• 2001

The optimum shape of header part in a PFHE (parallel-flow heat exchanger) is studied. The optimal values of each geometric parameter are proposed according to their order of influence with varying the four important parameters (the injection angle of working fluid ($\Theta$), the shape of inlet(S), the location of inlet ($y_c/D_{in}$) and the height of the protruding flat tube ( $y_{b/}$ $D_{in}$ )). The optimal geometric parameters are as follows:$\Theta= -21^{\circ}C,\; S=Type\; A \;an\;y_b/D_{in}$/=0. The heat transfer rate of the optimum model, compared to that of the reference model, is increased by about 55%. The optimal geometric parameters ran be applicable to the Reynolds number ranging from 5,000 to 20,000.0.

• International Journal of Oral Biology
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• 제35권4호
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• pp.145-151
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• 2010

Periodontitis is an inflammatory disorder of the periodontium and is characterized by destruction of the tooth supporting tissues, mediated by the upregulation of synthesis and release of a variety of pro-inflammatory factors. Inflammatory cytokines and prostaglandins upregulate RANKL and its subsequent binding to RANK stimulates osteoclast formation, resorption activity, and survival. In our present study, we investigated the effects of HP08-0111, composed of Coptis japonica (Thunb.) Makino, vitamin C and vitamin E, upon inflammatory responses, osteoclastogenesis and alveolar bone loss. HP08-0111 decreased the expression of IL-1$\beta$ and COX2 on LPS-induced RAW 264.7 cells and inhibited osteoclast-specific genes such as c-Fos, MMP-9, and TRAP. HP08-0111 also exhibited protective effects against alveolar bone loss in rats with ligature-induced periodontitis. Our results suggest that HP08-0111 is potentially an important therapeutic tool for the treatment of disorders associated with bone loss such as periodontitis.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2001년도 추계종합학술대회
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• pp.749-752
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• 2001

본 논문에서는 AIS 용 채널 접속 알고리즘을 분석하고 이를 구현하기 위한 모듈화 된 함수로 설계한 결과를 제시하였다. 먼저 ITU-R M.1371에서 규정한 RATDMA, ITDMA, FATDMA 및 SOTDMA 알고리즘의 기능을 분석하였으며 각각의 알고리즘을 모듈화 된 함수로 설계하였다. 설계한 채널 접속 알고리즘의 기능을 검증하기 위해 PC 상에서 C 언어를 이용하여 구현하고 모의 실험을 수행하였다. 실험 결과 설계한 채널 접속 알고리즘이 슬롯 할당을 제대로 수행함을 확인하였으며 표준안에서 제시한 요구를 만족함을 확인하였다.

• 한국결정학회지
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• 제8권2호
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• pp.124-126
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• 1997

[Ni(L)](ClO4)2(L:3,5,10,12-tetramethly-1,4,8,11-tetraazacyclotetradecane), C14H32Cl2N4NiO8, 착물은 NiN4 평면4각구조를 가지며 열력학적으로 가장 안정한 trans-III구조를 하고 있다.