• KSBB Journal
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• v.23 no.2
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• pp.169-176
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• 2008

The concentration of fresh gel from Aloe vera L. by using ulfrafiltration (UF) process was investigated and analyzed. The two membranes (organic and ceramic) with different molecular weight cut-off (MWCO) and modules (flat sheet and tubular) was used. Under optimum operation conditions, ceramic (zirconium dioxide) tubular membrane with MWCO of 50 kDa resulted in higher flux, less fouling, more turbid, higher total solid, higher polysaccharide and less aloin content. Optimum operation conditions were transmembrane pressure of 1.0 bar, feed velocity of 240 L/hr and temperature of $23^{\circ}C$. Volume concentration factor of aloe gel was 3.13 at permeate flux of $51.1\;L/m^2{\cdot}hr$ after processing time of 1.66 hr. Aloin in fresh aloe gel by UF process was effectively removed as permeate and bioactive polysaccharide content was 2.1 times higher than that of fresh aloe gel. These results allowed a very good level of concentration degree and polysaccharide content. Thus, ultrafiltration process of this study was suitable for the concentration of fresh aloe gel though the aloe concentrate showed both the viscosity decrease and partially separation of liquid layer during storage at $4^{\circ}C$.

• Korean Journal of Optics and Photonics
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• v.4 no.1
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• pp.15-21
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• 1993

This paper describes the design and development of a KrF excimer laser stepper and discusses the detailed system parameters and characterization data obtained from the performance test. We have developed a deep UV step-and-repeat system, operating at 248 nm, by retrofitting a commercial modules such as KrF excimer laser, precision wafer stage and fused silica illumination and 5X projection optics of numerical aperture 0.42. What we have developed, to the basic structure, are wafer alignment optics, reticle alignment system, autofocusing/leveling mechanisms and environment chamber. Finally, all these subsystem were integrated under the control of microprocessor-based controllers and computer. The wafer alignment system comprises the OFF-AXIS and the TTL alignment. The OFF-AXIS alignment system was realized with two kinds of optics. One is the magnification system with the image processing technique and the other is He-Ne laser diffraction type system using the alignment grating on the wafer. 'The TTL alignment system employs a dual beam inteferometric method, which takes advantages of higher diffraction efficiency compared with other TTL type alignment systems. As the results, alignment accuracy for OFF-AXIS and TTL alignment system were obtained within 0.1 $\mu\textrm{m}$/ 3 $\sigma$ for the various substrate on the wafers. The wafer focusing and leveling system is modified version of the conventional systems using position sensitive detectors (PSD). This type of detection method showed focusing and leveling accuracies of about $\pm$ 0.1 $\mu\textrm{m}$ and $\pm$ 0.5 arcsec, respectively. From the CD measurement, we obtained 0.4 $\mu\textrm{m}$ resolution features over the full field with routine use, and 0.3 $\mu\textrm{m}$ resolution was attainable under more strict conditions.

• Journal of the Institute of Convergence Signal Processing
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• v.15 no.1
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• pp.15-22
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• 2014

This paper presents the implementation of a control system of pellet boiler using wood pellet as carbon neutral material. The system also has the additional features to provide remote controlling and monitoring based on home networking technology through either public switched telephone networks or mobile communication networks. It consists of three kinds of sub-modules; a main controller provides basic and additional features such as a setting of temperature, a supplying of wood pellet, a controlling of ignition and fire-power, and a removing of soot. The second is temperature controller of individual rooms which is connected to the main controller through RS-485 links. And interface modules with PSTN and mobile networks can support remote controlling and monitoring the functions. The test results under the heating area of $172m^2$ show a thermal efficiency of 93.6%, a heating power of 20,640kcal/hr, and a fuel consumption of 5.54kg/hr. These results are superior to those of the conventional pellet boilers. In order to obtain the such high performance, we newly applied a 3-step ignition flow, a flame detection by $C_dS$ sensor, and a fire-power control by fine controlling of shutter to our pellet boiler.

• Molecules and Cells
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• v.43 no.5
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• pp.479-490
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• 2020

Interleukin-9 (IL-9) is well known for its role in allergic inflammation. For cancer, both pro- and anti-tumor effects of IL-9 were controversially reported, but the impact of IL-9 on tumor metastasis has not yet been clarified. In this study, IL-9 was expressed as a secretory form (sIL-9) and a membrane-bound form (mbIL-9) on B16F10 melanoma cells. The mbIL-9 was engineered as a chimeric protein with the transmembrane and cytoplasmic region of TNF-α. The effect of either mbIL-9 or sIL-9 expressing cells were analyzed on the metastasis capability of the cancer cells. After three weeks of tumor implantation into C57BL/6 mice through the tail vein, the number of tumor modules in lungs injected with IL-9 expressing B16F10 was 5-fold less than that of control groups. The percentages of CD4⁺ T cells, CD8⁺ T cells, NK cells, and M1 macrophages considerably increased in the lungs of the mice injected with IL-9 expressing cells. Among them, the M1 macrophage subset was the most significantly enhanced. Furthermore, peritoneal macrophages, which were stimulated with either sIL-9 or mbIL-9 expressing transfectant, exerted higher anti-tumor cytotoxicity compared with that of the mock control. The IL-9-stimulated peritoneal macrophages were highly polarized to M1 phenotype. Stimulation of RAW264.7 macrophages with sIL-9 or mbIL-9 expressing cells also significantly increased the cytotoxicity of those macrophages against wild-type B16F10 cells. These results clearly demonstrate that IL-9 can induce an anti-metastasis effect by enhancing the polarization and proliferation of M1 macrophages.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.11
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• pp.192-196
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• 1996

[ $1.06/1.32{\mu}m$ ] dual-wavelength medical laser was developed and preliminary clinical comparisons at these two wavelengths were performed for dental application. We could develop a compact laser system 1) by lasing two wavelengths from the same Nd:YAG rod, and 2) by introducing high-voltage switching power supply modules. Experiment on gingiva of pig jaw showed higher thermal damage at $1.32{\mu}m$. Depending on particular procedures, each wavelength has its own advantages and disadvantages. For cutting, however, using conical tips rather than bare fibers provided better results with low threshold of cutting energy and less surrounding thermal damage. Appling light-absorbing dye on target area appeared to induce more damage during laser irradiation. However, histological studies showed no significant difference whether dye was applied or not.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2003.07b
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• pp.1168-1171
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• 2003

In contrast to a conventional transformer, the flat transformer is made using a number of small ferrite cores. Two cores for transformer and one core for inductor, which composed one module. Many modules can be connected together to form a flat matrix transformer. This structural arrangement eliminates the single hot spot problem in conventional transformers and permits high current density pertains at high frequency. In this study, the ferrite magnetic cores of Mn-Zn system for the Flat transformer were manufactured and the electrical and magnetic characteristics of its tested. The power loss of sample FO2(Mn-Zn ferrite) sintered at $1350^{\circ}C$ was $350kW/m^3$ in test conditions of 250kHz, 200mT and $100^{\circ}C$, which showed the good power loss property in high frequency. The power loss of FO2 samples has been studied as a function of magnetic flux density and frequency. Steinmetz exponent was 2.82 at 250kHz and 2.73 at 500kHz. These results illustrated the switching of power loss mechanism in ferrite core from hysteresis losses to eddy current losses or others.

• Journal of Biosystems Engineering
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• v.33 no.2
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• pp.94-100
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• 2008

Present chemical application method using a power sprayer has been labor intensive, costly and ineffective. Therefore, a small agricultural unmanned helicopter was suggested to replace the conventional spray system. In this study, conceptual design for developing the helicopter and a consequential prototype were reported. The overall conceptual design was initiated by deciding the type of agricultural helicopter, as the single rotor helicopter with a tail system. As the first step of the designing, an air-cooled, 2-stroke engine was selected and a prototype transmission was designed by determining the rotating speed of main rotor shaft. A 'pusher' type tail rotor system was adapted to balance the reaction torque and reduce the power use. The tail boom length was designed to avoid the rotating trajectory of the main rotor. The RF console consisted of the engine control, attitude control, and emergency control modules. Assembling the prototype concluded the mechanical development of the agricultural helicopter.

• Proceedings of the KSME Conference
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• 2001.06d
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• pp.903-908
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• 2001

A web-based client/server program, MOVIDIK(Motor-Operated-Valve Integrated Database Information of KEPCO) has been developed to perform a design basis safety evaluation for a motor-operated-valve(MOV) in the nuclear power plant. The MOVIDIK consists of seven analysis modules and one administrative module. The analysis module calculates a differential pressure on the valve disk, thrust/torque acting at a valve stem, maximum allowable stress, thermal-overload-relay selection, voltage degradation, actuator output and margin. In addition, the administrative module manages user information, approval system and code information. MOVIDIK controls a huge amount of evaluation data and piles up the safety information of safety-related MOV. The MOVIDIK will improve the efficiency of safety evaluation work and standardize the analysis process for the MOV.

• Proceedings of the KSME Conference
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• 2001.11a
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• pp.865-870
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• 2001

For pneumatic system control, we need a data transmission system with high speed and high reliability or information interchange between main computer and solenoid valves and I/O devices. This paper presents a set of design techniques for a data communication system that is mainly used for pneumatic system control. For this purpose, we first designed hardware modules for an interface between central control module and local node that handles the operation of solenoid valves. In addition we developed a communication protocol for construction of RS-485 based multidrop network, and this protocol is basically designed with a kind of polling technique. Finally we evaluated performance of the developed system. The field test results show that, even under high noise environment, the data transmission of 375Kbps rate is possible up to 1,000m without using repeater. In addition, the system developed in this research is proved to be used easily for extension of a communication network because of its module structure.

• Korean Journal of Computational Design and Engineering
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• v.10 no.3
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• pp.188-198
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• 2005

There are two types of mold parts, ready-made standard parts and ETO (Engineered-to-Order) parts, the latter are of increasing importance to manufacturers. However, the ETO parts require more engineering support and communication than the ready-made standard parts. Existing e-Catalog modules provide classification structures of products that allow customers to select products based on their needs, and the trade begins with the provided specification. However, machine parts or mold parts have different purchasing patterns. Customers do not purchase the ready-made standard parts offered by an e-Catalog. They usually (1) add own options to the provided specifications or (2) change specification items such as length. To support these trades, a new e-Catalog system is proposed. The proposed system is based on the product design process and the specification selection process in addition to the parts classification structure.