• 한국정보통신학회논문지
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• 제15권10호
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• pp.2257-2264
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• 2011

무선 센서 네트워크에서 센서 노드들은 제한된 자원을 가지며, 에너지의 대부분을 통신에 소비한다. 대부분의 트래픽이 싱크 노드를 향해 전달되는 형태를 지니므로, 순간적인 네트워크 혼잡 발생 가능성이 높다. 네트워크 혼잡은 패킷의 폐기를 초래하고, 폐기된 패킷의 재전송으로 인하여 에너지가 낭비된다. 특히 싱크 노드로부터 멀리 위치한 센서 노드에서 생성된 패킷의 손실은 추가적인 에너지 소비를 나타낸다. 본 논문에서는 패킷의 우선순위와 혼잡 레벨 뿐만 아니라 홉 카운트를 고려하여 패킷 전송여부를 결정하는 트래픽 제어 메커니즘을 제안한다. 시뮬레이션 방법에 의한 성능 분석을 통해 제안된 메커니즘이 에너지 효율성을 개선한 하였다.

• Macromolecular Research
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• 제15권7호
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• pp.646-655
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• 2007

To achieve targeted drug delivery for chemotherapy, a ligand-mediated nanoparticulate drug carrier was designed, which could identity a specific receptor on the surfaces of tumor cells. Biodegradable poly(ethylene oxide)/poly$({\varepsilon}-caprolactone)$ (PEG/PCL) amphiphilic block copolymers coupled to biotin ligands were synthesized with a variety of PEG/PCL compositions. Block copolymeric nanoparticles harboring the anticancer drug paclitaxel were prepared via micelle formation in aqueous solution. The size of the biotin-conjugated PEG/PCL nanoparticles was determined by light scattering measurements to be 88-118 nm, depending on the molecular weight of the block copolymer, and remained less than 120 nm even after paclitaxel loading. From an in vitro release study, biotin-conjugated PEG/PCL nanoparticles containing paclitaxel evidenced sustained release profiles of the drug with no initial burst effect. The biotin-conjugated PEG/PCL block copolymer itself evidenced no significant adverse effects on cell viability at $0.005-1.0{\mu}g/mL$ of nanoparticle suspension regardless of cell type (normal human fibroblasts and HeLa cells). However, biotin-conjugated PEG/PCL harboring paclitaxel evidenced a much higher cytotoxicity for cancer cells than was observed in the PEG/PCL nanoparticles without the biotin group. These results showed that the biotin-conjugated nanoparticles could improve the selective delivery of paclitaxel into cancer cells via interactions with over-expressed biotin receptors on the surfaces of cancer cells.

• 한국수의병리학회지
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• 제5권1호
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• pp.1-4
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• 2001

Squamous cell carcinoma was diagnosed in a 4.5-year-old male African hedgehog (Atelerix albiventris). The patient was referred to Seoul National University, Veterinary Medical Teaching Hospital after 5 days history of left eye exophthalmos and corneal trauma. He had enlarged upper and lower jaw at the left part of the face and endophthalmitis of the left eye. On radiographic examinations, loss of bone density at the left zygomatic arch and sun-burst type periosteal reaction of left mandible with decreased bone density was noted. Histologically, the neoplastic mass consisted of markedly invasive, cords of nests of squamous epithelial cells. Intercellular bridges and keratin pearl formation were also noted.

• Korean Journal of Acupuncture
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• 제23권1호
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• pp.95-109
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• 2006

Objectives : There has been a considerable debate about how to best control for placebo effects in clinical trials of acupuncture. Recently several sham needles were developed and validated. This study aimed at summarising the validation studies of these needles and evaluating the outcomes of the randomised controlled trials (RCTs) using them. Methods : Computerised literature searches were performed using 'acupuncture' AND 'placebo OR sham' with a limitation of the results to RCTs in Medline via PubMed and the Cochrane Library. Only formally validated sham needle controlled studies were included. Data were extracted regarding study design, condition, sample size, credibility testing, intervention and outcomes. Methodological quality was assessed using a modified Jadad scale. Results : Three validated sham needles by Streitberger, Park, and Fink, were identified. Acupuncture's effectiveness for various conditions was tested using these needles in 12 RCTs. Real acupuncture was superior to sham acupuncture for rotator cuff tendonitis and hypertension. No significant differences between real acupuncture and sham acupuncture emerged for chemotherapy-related nausea and vomiting, postoperative nausea and vomiting, menstrually related migraine, acute stroke rehabilitation, chronic/episodic tension-type headache, neutrophil respiratory burst in healthy volunteers, alcohol withdrawal symptoms and chronic poststroke leg spasticity. Conclusions : The new sham devices have been adequately validated and may be useful tools for investigating specific research question. In spite of the sham needle's limits, the results of RCTs using such devices tend to suggest that the clinical effects of acupuncture are largely due to a placebo response.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1998년도 제13차 학술회의논문집
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• pp.295-300
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• 1998

In this paper, a real time diagnostic algorithm fur estimating the impact location by loose parts is proposed. It is composed of two modules such as the alarm discrimination module (ADM) and the impact-location estimation module(IEM). ADM decides whether the detected signal that triggers the alarm is the impact signal by loose parts or the noise signal. When the decision from ADM is concluded as the impact signal, the beginning time of burst-type signal, which the impact signal has usually such a form in time domain, provides the necessary data fur IEM. IEM by use of the arrival time method estimates the impact location of loose parts. The overall results of the estimated impact location are displayed on a computer monitor by the graphical mode and numerical data composed of the impact point, and thereby a plant operator can recognize easily the status of the impact event. This algorithm can perform the diagnosis process automatically and hence the operator's burden and the possible operator's error due to lack of expert knowledge of impact signals can be reduced remarkably. In order to validate the application of this method, the test experiment with a mock-up (flat board and reactor) system is performed. The experimental results show the efficiency of this algorithm even under high level noise and potential application to Loose Part Monitoring System (LPMS) for improving diagnosis capability in nuclear power plants.

• 천문학논총
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• 제30권2호
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• pp.57-58
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• 2015

In this study, we present geometrical and kinematical analysis of Moreton wave observed in 2012 June 3rd and July 6th, recorded in H-${\alpha}$ images of Global Oscillation Network Group (GONG) archive. These large-scale waves exhibit different features compared to each other. The observed wave of June 3rd has angular span of about $70^{\circ}$ with a diffuse wave front associated to NOAA active region 11496. It was found that the propagating speed of the wave at 17:53 UT is about $931{\pm}80km/s$. The broadness nature of this Moreton wave can be interpreted as the vertical extension of the wave over the chromosphere. On the other hand, the wave of July 6th associated with X1.1 class are that occurred at 23:01 UT in AR NOAA11515. From the kinematical analysis, the wave propagated with the initial velocity of about $994{\pm}70km/s$ which is in agreement with the speed of coronal shock derived from type II radio burst, v ~ 1100 km/s. These two identified waves add the inventory of the large-scale waves observed in 24th Solar Cycle.

• 한국통신학회논문지
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• 제22권5호
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• pp.1083-1096
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• 1997

To implement satellite B-ISDN/ATM network, it needs to gurantee reliable transport via satelite in the poor BER environment. So, it requires to use channel coding (FEC:Forward Error Correction) schemes for improvement of BER performance, but these coding effects evoke burst errors and degradation of the QoS. Therefore we have to investigate new algorithm that compensates these weaknesses. We consider convolutional coding and concatenated coding among FEC schemes as FEC for satellite transmission and choose different compensational algorithm by the error characteristics of the using type of FEC. In using concatenated coding, this paper proposes the satellite system structure for interconnection to the terrestrial network and proposes the channel coding algorithm for improvement of transmission performances. We execute performance evaluation of the proposed algorithm by computer simulation. In detail, we propose 4 types of application ATM cell to the block coding(Reed-Solomon) and propose the new 55 byte ATM cell that enforces the error correction capability of cell header by the BCH coding. Then we propose the outer interleaverand the cell unit interleaver that evoke maximum coding effect of BCH code.

• 한국통신학회논문지
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• 제34권1C호
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• pp.113-119
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• 2009

The training sequence with the appropriate length for equalization and initial synchronization is necessary before sending the pure data in the burst transmission type DS-UWB system. The length of the training sequence is one of the factors which make throughput decreased. The noble structure with the variable length of the training sequence whose length can be adaptively tailored according to the channel conditions (CM1,CM2,CM3,CM4) in the DS-USB systems is proposed. This structure can increase the throughput without sacrificing the performance than the method with fixed length of training sequence considering the worst case channel conditions. Simulation results under IEEE 802.15.3a channel model show that the proposed scheme can achieve higher throughput than a conventional one with the slight loss of BER performance. And this structure can reduce the computation complexity and power consumption with selecting the short length of the training sequence.

• 대한산업공학회지
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• 제25권2호
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• pp.162-172
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• 1999

For VBR video traffic, Motion-Picture Experts Group(MPEG) coding algorithm was adopted as the standard coding algorithm by International Telecommunication Union(ITU). In this paper, we propose a traffic model of an MPEG coded video traffic in frame level and cell level, and develop an approximate model for evaluating performance of a ATM multiplexer with homogeneous MPEG video sources by considering burst-level variation of aggregated traffics. For homogeneous MPEG video traffics which are frame-synchronized, the performance of the ATM multiplexer is influenced by source correlation at the multiplexing time. When sources are highly correlated, we decompose the aggregated cell streams by the frame-type and model multiplexing process during a frame time as n*D/D/1/K queueing model and suggest an approximate method for obtaining CLP of the ATM multiplexer. In the case that sources are highly correlated, the solution has the meaning of the upper bounds of performance of the ATM multiplexer. For the verification of our model, we compare the solution of our model with simulation resets. As the number of sources increases. The CLP obtained from our model approaches to simulation results, and gives upper bounds of simulation results.

• Macromolecular Research
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• 제8권2호
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• pp.80-88
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• 2000

Biodegradable microspheres were prepared with poly(L-lactide-co-glycolide) (PLGA, 75 : 25 by mole ratio) by an oil/oil solvent evaporation method for the sustained release of anti-AIDS virus agent, AZT The microspheres of relatively narrow size distribution (7.6$\pm$ 3.8 ㎛) were obtained by controlling the fabrication conditions. The shape of microspheres prepared was smooth and spherical. The efficiency of AZT loading into the PLGA microsphere was over 93% compared to that below 15% for microspheres by a conventional water/oil/water method. The effects of Preparation conditions on the morphology and in vitro AZT release pattern were investigated. in vitro release studies showed that different release pattern and release rates could be achieved by simply modifying factors in the fabrication conditions such as the type and amount of surfactant, initial amount of loaded drug, the temperature of solvent evaporation, and so on. PLCA microspheres prepared by 5% of initial drug loading, 1.0% (w/w) of surfactant concentration, and 25$\^{C}$ of solvent evaporation temperature were free from initial burst effect and a near-zero order sustained release was observed. Possible mechanisms of the near-zero order sustained release for our system have been proposed.