• International Journal of Fuzzy Logic and Intelligent Systems
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• 제13권1호
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• pp.31-38
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• 2013

Patients with heart disease need long-term monitoring of the electrocardiogram (ECG) signal using a portable electrocardiograph. This trend requires the miniaturization of data storage and faster transmission to medical doctors for diagnosis. The ECG signal needs to be utilized for efficient storage, processing and transmission, and its data must contain the important components for diagnosis, such as the P wave, QRS-complex, and T wave. In this study, we select the vertex which has a larger curvature value than the threshold value for compression. Then, we reconstruct the compressed signal using by radial basis function interpolation. This technique guarantees a lower percentage of root mean square difference with respect to the extracted sample points and preserves all the important features of the ECG signal. Its effectiveness has been demonstrated in the experiment using the Massachusetts Institute of Technology and Boston's Beth Israel Hospital arrhythmia database.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 2004년도 춘계학술대회 논문집
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• pp.530-537
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• 2004

Development of a versatile nanomanipulation tool is an overarching theme in nanotechnology. Such a tool will likely revolutionize the field given that it will enable fabrication and operation of a wealth of interesting nanodevices. This study seeks funding to create a novel nanomanipulation system with the ultimate goal of using this system for nanomanufacturing at the molecular level. The proposed design differs from existing approaches. It is based on a nanoscale ion trap integrated to a scanning prove microscope (SPM) tip. In this design, molecules to be assembled will be ionized and collected in the nanoscale ion trap all in an ultra high vacuum (UHV) environment. Once filled with the molecular ions, the nanoscale ion trap-SPM tip will be moved on a substrate surface using scanning probe microscopy techniques. The molecular ions will be placed at their precise locations on the surface. By virtue of the SPM, the devices that are being nanomanufactured will be imaged in real time as the molecular assembly process is carried out. In the later stages, automation of arrays of these nanomanipulators will be developed.

• The Journal of Korean Physical Therapy
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• 제22권5호
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• pp.77-82
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• 2010

Purpose: The purpose of this study was to compare the pathway of COP and plantar foot pressure and to determine the correlation between plantar regions during the ascending and descending of a ramp. Methods: Fifteen healthy adults who had no musculoskeletal problems participated in our study. They were asked to walk on a level surface and on an ascending and descending ramp in their bare feet. Pathway of COP and plantar foot pressures were recorded using the Matscan system (Tekscan, Boston, USA). For pressure measurements, the plantar foot surface was divided into seven regions: two toe regions, three forefoot regions, a midfoot region, and a heel region. To determine whether there was a statistically significant difference between pathway of COP and plantar foot pressures during walking, we used repeated measuremes ANOVA. Results: In comparison to results for a level walking, pathway of COP while ascending a ramp had a tendency to be shifted medially in the forefoot and became longer till the big toe. Pathway of COP while descending a ramp also was shifted medially, but ended in the forefoot. Plantar foot pressure of the second and third metatarsal head and the fourth and fifth metatarsal heads was significantly decreased while descending the ramp. Conclusion: These results indicated that plantar foot pressure is changed while ascending and descending a ramp and demonstrated that ramp walking can affect the structure and function of the foot. Therefore, gait environment is associated with significant changes in foot characteristics, which contribute to altered plantar loading patterns during gait.

• 동의신경정신과학회지
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• 제16권2호
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• pp.251-257
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• 2005

본 증례의 뇌경색 초피질감각실어증 환자는 한양방 치료 및 언어치료 시행을 통하여 K-WAB, K-BNT 등 표준화된 실어증 검사의 수행능력의 향상을 보였으며, 이야기 배열 과제에 대한 발화 분석에서 주제진술률의 향상, 의미착어와 음소착어의 감소 등 실제적 담화능력의 향상을 나타내었다. 실어증 환자의 경과관찰에서 이야기배열그림이 활용이 유용하리라 사료된다. 이후, 한방치료의 효과를 검증 및 이야기 배열과제 발화분석의 유용성에 대한 확대된 연구가 필요하다.

• 한국정밀공학회지
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• 제20권5호
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• pp.218-224
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• 2003

This paper describes a novel MEMS integration technique on a CMOS chip. MEMS integration on CMOS circuit has many advantages in view of manufacturing cost and reliability. The surface topography of a CMOS chip from a commercial foundry has 0.9 ${\mu}{\textrm}{m}$ bumps due to the conformal coating on aluminum interconnect patterns, which are used for addressing each MEMS element individually. Therefore, it is necessary to achieve a flat mirror-like CMOS chip fer the microelectromechanical system (MEMS) such as micro mirror array. Such CMOS chip needs an additional thickness of the dielectric passivation layer to ease the subsequent planarization process. To overcome a temperature limit from the aluminum thermal degradation, this study uses RF sputtering of silicon nitride at low temperature and then polishes the CMOS chip together with the surrounding dummy pieces to define a polishing plane. Planarization reduces 0.9 ${\mu}{\textrm}{m}$ of the bumps to less than 25 nm.

• Nutrition Research and Practice
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• 제9권2호
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• pp.117-122
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• 2015

BACKGROUND/OBJECTIVES: Curcumin, a major component of the Curcuma species, contains antioxidant and anti-inflammatory properties. Although it was found to induce apoptosis in cancer cells, the functional role of curcumin as well as its molecular mechanism in anti-inflammatory response, particularly in intestinal cells, has been less investigated. The intestine epithelial barrier is the first barrier and the most important location for the substrate coming from the lumen of the gut. SUBJECTS/METHODS: We administered curcumin treatment in the human intestinal epithelial cell lines, T84 and Caco-2. We examined endoplasmic reticulum (ER) stress response by thapsigargin, qPCR of XBP1 and BiP, electrophysiology by wild-type cholera toxin in the cells. RESULTS: In this study, we showed that curcumin treatment reduces ER stress and thereby decreases inflammatory response in human intestinal epithelial cells. In addition, curcumin confers protection without damaging the membrane tight junction or actin skeleton change in intestine epithelial cells. Therefore, curcumin treatment protects the gut from bacterial invasion via reduction of ER stress and anti-inflammatory response in intestinal epithelial cells. CONCLUSIONS: Taken together, our data demonstrate the important role of curcumin in protecting the intestine by modulating ER stress and inflammatory response post intoxication.

• Journal of Applied Biological Chemistry
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• 제49권4호
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• pp.143-147
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• 2006

A rapid PCR-based assay for detecting hepatitis B viral DNA(HBV DNA) in serum and plasma was developed using a new PCR instrument named GenSpector(TMC-1000, Samsung electronics). PCR was carried out using a chip-based platform, which enabled 50 PCR cycles with internal controls, and melting-curve analysis in 30 minutes. Verification of the amplified HBV DNA product and the internal control was based on specific melting temperatures(Tm) analysis, executed by the GenSpector software. Primers were designed within the region conserved through HBV genotypes A to F. The lower limit of detection was 840 copies/ml serum, conducted with serial dilutions of a HBV DNA positive control(ACCURUN 325 series 700, Boston Biomedica Inc.). The assay was also compared to another assay for HBV DNA(Versant HBV DNA 3.0 assay, Bayer HealthCare) for 200 samples(each 100 clinical negative and positive samples). The sensitivity and specificity were 100% matched. This rapid PCR-based assay is specific, reproducible, and enables qualitative detection of HBV DNA.

• The Journal of Asian Finance, Economics and Business
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• 제4권2호
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• pp.69-74
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• 2017

The purpose of this research is to be acquainted with the awareness and approval of halal supply chain among Indian manufacturers and distribution network members for haulage and warehousing activities from the perception of respective service suppliers. A total of 20 respondents, which consist of 10 transportation companies and 10 warehousing companies from the State of Andhra Pradesh in India were selected for the study by using purposive sampling method. The principal focal points of the discussions are on awareness and adoption of halal transportation and warehousing services chosen for the study in the comprehensive halal supply chain. A total of 90 percent and 70 percent of respondents from the transportation and warehousing companies respectively agreed that they know only about the concept of halal but do not have any exposure and ken on the halal supply chain. However, findings of this research won't have extensive validity in the market, gaining an enough familiarity with the halal supply chain in the Indian social context is of immense importance. This is a pioneering attempt aimed to investigate the awareness and adoption levels of halal supply chain among Indian businessmen which are precious for supply chain companies to customize their services in the country as well to the world of academia.

• The Journal of Asian Finance, Economics and Business
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• 제5권3호
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• pp.7-17
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• 2018

This paper examines short-run and long-run dynamic relationships between selected macroeconomic variables and stock prices in the Korea Stock Exchange. The data is restricted to the period for which monthly data are available from January 1986 to October 2016 (370 observations) retrieved from the Economic Statistics System database sponsored by the Bank of Korea. The study employs unit root test, cointegration test, vector error correction estimates, impulse response test, and structural break test. The results of the Johansen cointegration test indicate at least three cointegrating equations exist at the 0.05 level in the model, confirming that there is a long-run equilibrium relationship between stock prices and macroeconomic variables in Korea. The results of vector error correction model (VECM) estimates indicate that money supply and short-term interest rate are not related to stock prices in the short-run. However, exchange rate is positively related to stock prices while the industrial production index and inflation are negatively related to stock prices in the short-run. Furthermore, the VECM estimates indicate that the external shock, such as regional and global financial crisis shocks, neither affects changes in the endogenous variables nor causes instability in the cointegrating vector. This study finds that the endogenous variables are determined by their own dynamics in the model.

• Journal of Electrochemical Science and Technology
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• 제11권4호
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• pp.406-410
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• 2020

Despite a simple preparation of manganese oxide (MnO₂) nanowires by electrodeposition, the improvement in specific capacitance (C_sp) and voltammetric response of the MnO₂ nanowire-based electrodes has been quite limited. This is attributed to the poor electrical conductivity of MnO₂ and its dense bulk morphology due to the aggregation of the nanowires. This study investigated the capacitive performance of MnO₂ nanowires electrodeposited on agarose thin films. The good ionic conductivity and porous network of the agarose film provided favorable growth conditions for the MnO₂ nanowires with suppressed aggregation. A maximum C_sp value of 686 F/g measured at a scan rate of 10 mV/s was obtained, which was significantly larger than that of 314 F/g for the agarose-free MnO₂ electrode at the same scan rate. The rate capability was also improved. The C_sp measured at a high scan rate of 100 mV/s retained 74.0% of the value measured at 10 mV/s, superior to the retention of 71.1% for the agarose-free MnO₂ electrode.