• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.11
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• pp.3405-3411
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• 2009

This study was performed to be used as basic data to preventive the osteoporosis of a rural community people, after finding out the bone mineral density and a state of health, that of exercise, body composition and basic physical strength of the rural community adult. the subject for 143 adults of a rural community, the relation between bone mineral density and a state of health, that of exercise, body measurement and basic physical strength was studied. The research results were as follows. 1. In survey subjects, the more the age increased(p<0.01) and the lower the educational level was, the lower bone mineral density was(p<0.05). 2. Bone mineral density was significantly lower in those who had chronic diseases than those who didn't (p<0.05). 3. Bone mineral density was significantly higher in those who had much weight, BMI, body fat mass, and fat-free mass than those who didn't(p<0.01). 4. Bone mineral density was significantly high in those who exercised in the past, whose basal metabolism was high, and whose muscle mass was much(p<0.05). 5. Bone mineral density was high in those who had much grasping power and a number of sit-ups and push-ups (p<0.01). 6. As a result of Multiple Regression Analysis in which BMD was a dependent variable, the more the age increased, the more the score of bone density decreased when they had chronic diseases. And the exercise of the past affected the increase of bone mineral density.

• BMB Reports
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• v.43 no.9
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• pp.579-583
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• 2010

The adipocyte-derived hormone leptin regulates appetite and bone mass. Recent research demonstrates that reciprocally, osteoblasts have a role in controlling energy metabolism. Several genes expressed in osteoblasts are involved in this process, and one of them is the Esp gene. The remaining genes regulate Esp gene expression. OST-PTP, the protein name of Esp, regulates the carboxylation of osteocalcin secreted from osteoblasts, thus affecting insulin sensitivity and insulin secretion. This review provides evidence for a novel interpretation of the connection between bone and energy metabolism and expands our understanding of the novel physiology of bone beyond its classical functions.

• Journal of Korean Neurosurgical Society
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• v.56 no.6
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• pp.509-512
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• 2014

Primary intraosseous meningioma is a rare tumor, and atypical pathologic components both osteolytic lesion and dura and soft tissue invasion is extremely rare. A 65-year-old woman presented with a 5-month history of a soft mass on the right frontal area. MR imaging revealed a 4 cm sized, multilobulated, strongly-enhancing lesion on the right frontal bone, and CT showed a destructive skull lesion. The mass was adhered tightly to the scalp and dura mater, and it extended to some part of the outer and inner dural layers without brain invasion. The extradural mass and soft tissue mass were totally removed simultaneously and we reconstructed the calvarial defect with artificial bone material. The pathological study revealed an atypical meningioma as World Health Organization grade II. Six months after the operation, brain MR imaging showed that not found recurrence in both cranial and spinal lesion. Here, we report a case of primary osteolytic intraosseous atypical meningioma with soft tissue and dural invasion.

• Journal of Home Health Care Nursing
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• v.25 no.1
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• pp.25-36
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• 2018

Purpose: The purpose of this study was to review the literature to explore the relationship between body mass index (BMI) and bone mineral density (BMD) in elderly using an integrative review. Methods: The keywords 'osteoporosis,' 'body mass index,' and 'bone mineral density' were used to search peer-reviewed publications through four databases. Among 1,389 searched articles, eight articles were selected after excluding those that did not meet the inclusion criteria. Results: Seven articles stated that BMI was positively associated with BMD among elderly. In the elderly, the prevalence of osteoporosis was 25-55.7% in women, and 11-13% in men. Conclusion: This study found that high BMI may be helpful to increase BMD among elderly although the mechanism was not clear. It is necessary to identify BMD and fractures in elderly according to body composition in future research.

• Journal of Veterinary Clinics
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• v.33 no.1
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• pp.48-50
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• 2016

A 10-year-old spayed female Maltese dog weighting 3.4 kg was referred with growing firm mass at the parietal bone region from 2 weeks ago. A firm, partially calcified mass ($1.9cm{\times}4.4cm$) was palpated in the region of the frontal and parietal skulls but had no neurologic signs. Computed tomography (CT) characteristics of mass were round to oval shape, fine granular appearance, and well defined margins. Mass involving the calvarial bones had invasion into the cranial vault with a significant intracranial portion. Histologically, the tumor was characterized by the presence of multiple lobules containing osteoid or cartilage in the center that were separated by anastomosing fibrous septae. This is case report described the clinical and histopathological features of multilobular tumor of skull in a Maltese dog.

• Korean Journal of Bronchoesophagology
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• v.19 no.1
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• pp.28-30
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• 2013

Foreign bodies in the oral cavity and pharyngolarynx are frequently observed accidental cases in the otolaryngological fields. Most foreign bodies can be recognized and removable with the manipulation of endoscopes and various instruments. However, foreign bodies that penetrate the oral cavity and oropharynx to appear as a tongue mass are rare. Therefore, such cases easily can be misconceived as tongue tumor at first, so it must involve a more thorough search utilizing such aids as computed tomography. Depending on their location and size, their removal may involve surgical intervention. The authors experienced such a rare case of an elderly male patient, presenting as tongue mass. We hereby report this case along with the relevant literature.

• Korean Journal of Veterinary Pathology
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• v.5 no.2
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• pp.81-83
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• 2001

A white-yellowish 5-7 cm sized solid mass was observed in the mammary gland of a 7 years old poodle bitch. Mass was well-defined and metastasis was not observed. In microscopic findings, mass contained hyperplasia of glandular epithelial cells, proliferation of mucin-secreting myoepithelial cells and their stroma and formation of cartilage and bone. Bone marrow with fat and hematopoietic cells was observed. Based on the microscopic findings, the mass was diagnosed as benign mixed tumor of the mammary gland in dog.

• Experimental and Molecular Medicine
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• v.50 no.12
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• pp.3.1-3.14
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• 2018

Type 1 diabetes mellitus (T1DM) is a pathological condition associated with osteopenia. $WNT/{\beta}$-catenin signaling is implicated in this process. Trabecular and cortical bone respond differently to $WNT/{\beta}$-catenin signaling in healthy mice. We investigated whether this signaling has different effects on trabecular and cortical bone in T1DM. We first established a streptozotocin-induced T1DM mouse model and then constitutively activated ${\beta}$-catenin in osteoblasts in the setting of T1DM (T1-CA). The extent of bone loss was greater in trabecular bone than that in cortical bone in T1DM mice, and this difference was consistent with the reduction in the expression of ${\beta}$-catenin signaling in the two bone compartments. Further experiments demonstrated that in T1DM mice, trabecular bone showed lower levels of insulin-like growth factor-1 receptor (IGF-1R) than the levels in cortical bone, leading to lower $WNT/{\beta}$-catenin signaling activity through the inhibition of the IGF-1R/Akt/glycogen synthase kinase $3{\beta}$ ($GSK3{\beta}$) pathway. After ${\beta}$-catenin was activated in T1-CA mice, the bone mass and bone strength increased to substantially greater extents in trabecular bone than those in cortical bone. In addition, the cortical bone of the T1-CA mice displayed an unexpected increase in bone porosity, with increased bone resorption. The downregulated expression of WNT16 might be responsible for these cortical bone changes. In conclusion, we found that although the activation of $WNT/{\beta}$-catenin signaling increased the trabecular bone mass and bone strength in T1DM mice, it also increased the cortical bone porosity, impairing the bone strength. These findings should be considered in the future treatment of T1DM-related osteopenia.

• Nutritional Sciences
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• v.8 no.1
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• pp.71-76
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• 2005

The purpose of this study was to investigate the relationship between nutritional status of iron and bone minernl density in premenopausal women. In the study, we classified the subjects into osteopenia (-2.5-I, n=29) groups according to their lumbar spine bone mineral density. Anthropometric measurements, dietary intake analysis and blood biochemistry measurements were performed on the subjects. The average ages of those in the osteopenia and normal groups were 22.2 yrs and 23.0 yrs, respectively, with no significant difference. The average body mass index (p<0.05) of those in the osteopenia group (19.6) was significantly lower than that of the normal group (21.3). The mean protein intake of those in the osteopenia group was significantly lower than that (p<0.05) the subjects in the normal group. The osteopenia group consumed a significantly lower amount of iron (p<0.05) and non-heme iron (p<0.05) compared to the normal group. The intakes of total food, vegetables and milk of those in the osteopenia group were significantly lower than those of the subjects in the normal group. The serum ferritin (p<0.001) level of those in the osteopenia group was significantly lower than those of the subjects in the normal group. In conclusion, a balance of iron status may be helpful in the prevention of bone mass loss in premenopausal young women.

• Korean Journal of Adult Nursing
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• v.19 no.3
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• pp.389-400
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• 2007

Purposes: This study was designed to explore the stage distribution of subjects according to stage of change for calcium intake and for exercise, and to identify factors that could discriminate among subjects in various stages. Methods: The sample consisted of 142 subjects who had taken bone mineral densitometry tests. The instruments used in this study were the Stage Placement Instrument for Calcium Intake and Exercise, the Osteoporosis Health Belief Scale and the Osteoporosis Knowledge Test, and the Osteoporosis Self Efficacy Scale. Data were analyzed using chi square, ANOVA, and discriminant analysis by using the SPSS 12.0 program. Results: For calcium stages, economic level, calcium knowledge, positive social norms for calcium intake, & educational level showed high standardized canonical discriminant function coefficients. For exercise stages, exercise efficacy, susceptibility, exercise benefit, educational level, positive social norm to exercise, educational level, and exercise barrier showed high standardized canonical discriminant function coefficients. Conclusion: This study implies that bone mass promoting program incorporating a stages of change model can be applied as useful nursing intervention.