• Journal of the Korean Society for Precision Engineering
• /
• v.30 no.9
• /
• pp.991-999
• /
• 2013

Lower limbs deformity is a congenital disease and can also be occurred by an acquired factor. This paper suggests a new technique for surgical planning of Corrective Osteotomy for Lower Limbs (COLL) using 2D-3D medical image registration. Converting to a 3D modeling data of lower limb based on CT (computed tomography) scan, and divide it into femur, tibia and fibula; which composing the lower limb. By rearranging the model based on the biplane 2D images of X-ray data, a 3D upright bone structure was acquired. There are two ways to array the 3D data on the 2D image: Intensity-based registration and feature-based registration. Even though registering Intensity-based method takes more time, this method will provide more precise results, and will improve the accuracy of surgical planning.

• The Journal of the Korean bone and joint tumor society
• /
• v.11 no.1
• /
• pp.17-24
• /
• 2005

Local treatment for tumors has developed from extended radical surgery to function preserving surgery on the basis of modern biology. With the development of minimally invasive technique, it changed to be minimal-invasive surgery. And nowadays technical revolution made non-invasive surgery possible with appearance of several kinds of non-surgical knives such as gamma knife, cyber knife, and HIFU (high intensity focused ultrasound) knife. In this article, history, HIFU machine and treatment procedure, histological change and its mechanism, clinical applications, advantage, disadvantage, and future prospect of extracorporeal high intensity focused ultrasound therapy using HIFU knife will be reviewed.

• Asian-Australasian Journal of Animal Sciences
• /
• v.12 no.2
• /
• pp.287-294
• /
• 1999

Vitamin and mineral deletion from swine diets can result in reduced growth if done during the period wher muscle and bone development is occurring. Several of the vitamins and minerals decline in the serum during the starter period, suggesting a higher dietary inclusion may be necessary postweaning. Vitamin research with grower-finisher pigs is limited, but results suggest that rapidly growing lean pigs may have a higher dietary requirement for the B vitamins. Several studies have suggested that early weaning and pigs of a lean genotype may have a dietary requirement for vitamin C, CI and Cr. High dietary vitamin E levels are fortified in the diet and seems to be effective in preventing mulberry heart problems in weanling and grower pigs. Organic Se is more effectively retained in muscle tissue than inorganic Se, approximately 20% less is excreted, but the bioavailability of organic Se for glutathione peroxidase activity is only 80 to 90% to that of sodium selenite. The active form of thyroxine (T4) is dependent upon a Se containing enzyme. Withdrawal of vitamins and minerals during the latter part of the finisher period has not affected pig performance responses, but studies with poultry suggest that the vitamin content of the meat may be reduced if the vitamins are withdrawn prior to marketing. High levels of vitamin E have been shown to improve pork quality, by reducing drip loss. Studies with vitamin C and Se have suggested that they may also be involved in pork quality.

• Asian-Australasian Journal of Animal Sciences
• /
• v.10 no.6
• /
• pp.671-678
• /
• 1997

The objective was to evaluate method of feeding (free access or intubation), method of slaughter (carbon dioxide gas or barbiturate) and digesta flushing medium (distilled water or physiological saline), in the development of an ileal amino acid digestibility assay for 4 week-old broiler chickens. Three diets were used (commercial (C), semi-synthetic meat-and bone meal (MBM) or wheat (W)). For the coarser C and W diets but not for the MBM diet, feeding method had a significant effect on concentrations of chromium (Cr), nitrogen (N), acid detergent fibre (ADF) and neutral detergent fibre (NDF) in the crop contents at a set time after a meal. There appeared to be a selection of food particles under free-access feeding. For birds receiving the wheat diet there was an effect (p < 0.05) of sampling time after feeding on the concentrations of Cr, N, ADF and NDF/Cr in the crop contents. Flushing ileal digesta with distilled water or saline led to similar apparent ileal N digestibility coefficients. Birds given the MBM diet, and killed by inhalation of $CO_2$, had significantly (p < 0.05) lower apparent ileal N digestibility coefficients (73 versus 80%) than those killed by barbiturate overdose.

• Asian-Australasian Journal of Animal Sciences
• /
• v.21 no.9
• /
• pp.1376-1382
• /
• 2008

The carcass characteristics and composition of both male and female commercial broiler chickens (CB) and the red jungle fowl (RJF) were compared at a common body weight of $800{\pm}25.6g$. The RJF and CB were 133 and 17 d of age, respectively, when they reached 800 g. The yields of breast and thigh portions and their muscle to bone ratios were higher for RJF as compared to CB. On the other hand, the latter had significantly greater hearts, livers and gizzards. The weights of the whole thigh and drumstick, and their muscles were lower in females than males. The CB had more abdominal fat than RJF. While sex had no significant effect on the absolute weights of abdominal fats in CB, the female RJF were fatter than their male counterparts. The fat and cholesterol contents of the breast and leg muscles of CB were significantly higher than those of RJF. The opposite was noted for protein content of both muscles. The effect of sex on fat and cholesterol contents varied according to muscle type. Comparison of CB and RJF at a common body weight suggested that the rate of development of body components have changed concomitantly with selection for rapid growth in the former.

• Preventive Nutrition and Food Science
• /
• v.11 no.2
• /
• pp.105-109
• /
• 2006

Pinus densiflora belongs to the Pinaceae family which has been widely used for health promoting purposes as folk medicine or as a food. Various curative effects of different parts of the pine have been reported including as a remedy for carcinoma. We examined the effects of pine needle water extracts (PNE) on macrophage function using peritoneal macrophage, pre-osteoclast bone macrophage (Raw 264.7 cell) and brain macrophage (C6 microglia). When peritoneal macrophages were treated with various concentrations of PNE ($1{\sim}100{\mu}g/mL$) for 24 hours, phagocytic activity was significantly increased, whereas it had no effect on tumoricidal activity and NO production. However, the treatment of Raw 264.7 with PNE resulted in the enhancement of NO production at high concentration ($100{\mu}g/mL$). Furthermore, the treatment of C6 with PNE increased the production of NO in a concentration-dependent manner, whereas PNE suppressed NO production in $LPS/IFN-{\gamma}-stimulated$ microglia. These results suggest that PNE has differential immunomodulatory effects on macrophages.

• Journal of Korean Academy of Nursing
• /
• v.30 no.3
• /
• pp.764-775
• /
• 2000

The purpose of this study was to develop the educational program based on the self-efficacy theory of Bandura(1986) and to identify the effect of the program among women. For this purpose a non-equivalent control group, and a pretest- posttest design was used between the experimental and the control group. The subjects in this study were female and were over the age 40, 37 in the experimental group and 46 in the control group. In this study, the educational program was developed to increase the level of osteoporosis self efficacy and to prevent osteoporosis. The program consisted of watching, videotapes, telephone contact, lectures, and small group discussions. This study was conducted to determine whether the 6 month educational program would increase osteoporosis self- efficacy, thus modifying life styles related to osteoporosis increas BMD. The instruments utilized in this study were the Lifestyle Questionnaire, and the Osteoporosis Self-Efficacy Scale. Also, bone marrow density (BMD) on the left wrist was measured by DTX-200. The findings are as follows: 1. A significant decrease in BMD was observed in the control group. By contrast, no significant change in BMD was observed in the experimental group. 2. The Osteoporosis Self-Efficacy was not significantly changed in both the experimental and control groups. 3. In the experimental group, the number of exercise participants and their exercise times were significantly increased. Also the amount of caffeine intake was significantly decreased.

• International Journal of Oral Biology
• /
• v.33 no.4
• /
• pp.187-195
• /
• 2008

Reparative dentine formation requires newly differentiated odontoblast-like cells. Therefore, identification of the molecule that stimulates the odontogenic differentiation of precursor cells in the tooth pulp will be helpful for the development of strategies to repair damaged pulp. In this study, we examined the effect of N-acetylcysteine (NAC) on the odontogenic differentiation of MDPC-23 cells, a mouse odontoblast-like cell line derived from dental papilla, and primary cultured rat dental papilla cells (RDPCs). NAC (1-30 mM) suppressed production of reactive oxygen species in MDPC-23 cells in a dose-dependent manner. Although 5 to 20 mM NAC did not alter MDPC-23 cell proliferation, 1 or 30 mM NAC significantly inhibited it. NAC enhanced mineralized nodule formation and the expression of several odontoblast differentiation-associated genes in both RDPCs and MDPC-23. This NAC stimulatory effect was significant, even at concentrations lower than 1 mM. However, NAC did not stimulate expression of bone morphogenetic protein-2, -4, or -7, which are known to enhance odontogenic differentiation. Since reactive oxygen species are also involved in the pulp toxicity of resin-based restorative materials, these results suggest that NAC may be a promising candidate for supplementation of dental restorative materials in order to enhance reparative dentine formation.

• Imaging Science in Dentistry
• /
• v.44 no.1
• /
• pp.1-6
• /
• 2014

Professionals performing radiographic examinations are responsible for maintaining optimal image quality for accurate diagnoses. These professionals must competently execute techniques such as film manipulation and processing to minimize patient exposure to radiation. Improper performance by the professional and/or patient may result in a radiographic image of unsatisfactory quality that can also lead to a misdiagnosis and the development of an inadequate treatment plan. Currently, the most commonly performed extraoral examination is panoramic radiography. The invention of panoramic radiography has resulted in improvements in image quality with decreased exposure to radiation and at a low cost. However, this technique requires careful, accurate positioning of the patient's teeth and surrounding maxillofacial bone structure within the focal trough. Therefore, we reviewed the literature for the most common types of positioning errors in panoramic radiography to suggest the correct techniques. We would also discuss how to determine if the most common positioning errors occurred in panoramic radiography, such as in the positioning of the patient's head, tongue, chin, or body.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2006.05a
• /
• pp.517-518
• /
• 2006

In this study, a commercial fixation device, BioFlex, which was designed with shape memory alloy(SMA) for dynamic stabilization of spine was biomechanically evaluated. The finite element model of intact lumbar spine from L1 to S was developed using CT images. Also, low FE models of 2-level(L4-L5-S) and 3-level(L3-L4-L5-S) posteriori fixation using titanium(Ti) rod and BioFlex(SMA) rod. The rotations of bone segments in the intact model and four models were predicted. Although the rotations of the BioFlex fixation model were smaller than those of the intact model, they were relatively larger than those of Ti fixation. The present can be applied for not only evaluation of the stability of interbody fixator, but also development of new implant.