• 제목/요약/키워드: Bok-l

검색결과 1,022건 처리시간 0.029초

천속단의 성분(II) (Chemical Constituents of Dipsacus asper (II))

  • 권용수;김관오;이진훈;손순주;원희목;장복심;김창민
    • 생약학회지
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    • 제34권2호통권133호
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    • pp.128-131
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    • 2003
  • Four compounds were isolated from the roots of Dipsacus asper roots, and were identified as methyl 3,5-di-O-caffeoyl quinate, 3,5-di-O-caffeoyl quinic acid, sitosterol $3-O-{\beta}-D-Glucopyranoside$ and hederagenin $3-O-{\alpha}-L-arabinopyranoside$. Among the isolated compounds, methyl 3,5-di-O-caffeoyl quinate and 3,5-di-O-caffeoyl quinate acid have never been reported previously from this plant.

Pseudomonas aeruginosa KGM-100이 생산하는 항생물질의 특성 및 구조 (Characterization and Structural Dtercination of an Antifungal Compound Produced by Pseudomonas aeruginosa KGM-100)

  • 김경석;홍수형;이은주;박용복;박용태;하지홍
    • 한국미생물·생명공학회지
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    • 제23권1호
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    • pp.98-103
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    • 1995
  • During the screening of antifungal antibiotics from microbial metabolites, we selected Pseudomonas aeruginosa KGM-100 showing powerful antagonistic activity against various phytopathogenic fungi. Antibiotics KGM-100A and KGM-100B were purified from the culture broth of Pseudomonas aeruginosa KGM-100 by diaion HP-20 column chromatography, ethyl acetate extraction, silica gel column chromatography, preparative TLC and recrystallization. KGM-100A which was recrystallized in MeOH showed antimicrobial activities against a broad spectrum of fungi and bacteria. Physico-chemical properties of KGM-100A were determined and identified to be phenazine-l-carboxylic acid by UV, IR, $^{1}$H-NMR, $^{13}$C-NMR, mass spectrum, and elemental analyses.

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Epiduroscopic Removal of a Lumbar Facet Joint Cyst

  • Jin, Hyun Seung;Bae, Jun Yeol;In, Chi Bum;Choi, Eun Joo;Lee, Pyung Bok;Nahm, Francis Sahngun
    • The Korean Journal of Pain
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    • 제28권4호
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    • pp.275-279
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    • 2015
  • Facet joint synovial cysts are usually associated with osteoarthritis of the adjacent facet joint and/or spondylolisthesis. In between the conservative and operative ends of the treatment spectrum lie minimally invasive techniques such as cyst rupture using epiduroscopy. In this report, we describe an 82-year-old male patient presenting with low back pain radiating to his lower left extremity and associated paresthesia. Magnetic resonance imaging of the lumbar spine revealed a synovial cyst at left L4/5 facet joint. Using epiduroscopy, the cyst was mechanically ruptured by popping it with the tip of the scope. The patient remained symptom-free at his successive visits until 12 months after the procedure, and was opened for desired follow up.

Biodegradation of Toluene using Biofilms in a Bubble Column Bioreactor

  • Choi, Yong-Bok;Lee, Jang-Young;Kim, Hak-Sung
    • Journal of Microbiology and Biotechnology
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    • 제5권1호
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    • pp.41-47
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    • 1995
  • Biodegradation of toluene in liquid effluent stream was carried out using biofilms of Pseudomonas putida formed on celite particles in the bubble column bioreactor. Silicon rubber tubing was installed at the bottom of the bioreactor and liquid toluene was circulated within the tubing. Toluene diffused out of the tube wall and was transferred into the culture broth where degradation by biofilms occurred. The operating variables affecting the formation of biofihns on celite particles were investigated in the bubble column bioreactor, and it was found that formation of bifilm is favored by high dilution rate and supply rate of carbon source which stimulate the growth of initially attached cells. Continuous biodegradation of toluene using biofilms was stablely conducted in the bioreactor for more than one month without any significant fluctuation, showing a removal efficiency higher than 95% at the toluene transfer rate of 1.2 g/L/h.

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우리나라 남부연안에서 채집된 짧은수염대구(Laemonema nana)의 형태적 특징 (Morphological Characteristics of Laemonema nana (Moridae) Collected from the Southern Coastal Waters of Korea)

  • 김맹진;최정화;최광호;송춘복
    • 한국수산과학회지
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    • 제47권5호
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    • pp.667-670
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    • 2014
  • Six adult fish of Laemonema nana, belonging to the family Moridae, were collected in a bottom trawl in the southern coastal waters of Korea. These specimens were characterized by having 46-52 second dorsal fin rays (vs. 57-67 for Lotella phycis and 68 for Physiculus japonicus), two pelvic fin rays (vs. 9 for L. phycis and 6-7 for P. japonicus), and lateral line descending abruptly below the anterior part of the second dorsal fin.

NK cell and macrophage activation is associated with anti metastatic effect of Korean mistletoe lectins

  • Yoon, Taek-Joon;Yoo, Yung-Choon;Kang, Tae-Bong;Lee, Kyung-Bok;Kim, Jong-Bae
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.148.2-149
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    • 2003
  • The inhibitory effect of the lectins (KML-C) isolated from Korean mistletoe (KM; Viscum album coloratum), on tumor metastases produced by highly metastatic murine tumor cells, B 16-BL6 melanoma, colon 26-M3.1 carcinoma and L5178Y-ML25 lymphoma cells, was investigated in syngeneic mice. (omitted)

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Isoguanosine과 Berberine 1 : 1 혼합물의 항암효과 (Anti-tumor Activity of Isoguanosine and Berberine 1 : 1 mixture)

  • 김정한;이상준;한영복;문정조;김종배
    • 약학회지
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    • 제38권2호
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    • pp.174-178
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    • 1994
  • Isoguanosine and berberine 1:1 mixture[l:[1(mole:mole)] has been prepared and evaluated by measuring antitumor effects against various tumor cell lines in culture and in mice. We reported that the synergistic effect of isoguanosine and berberine mixture has been revealed compared with each of isoguanosine and berberine increased by $3{\sim}8$ times than that of each components in various tumor cell lines in vitro. The most effective dose of isoguanosine and berberine mixture was 60 mg/kg/day in mice bearing S-180 solid tumor, the %(1-T/C) values were 70%. Against the P-388 leukemia, isoguanosine-berberine mixture was the most effective at the dose of 60 mg/kg/day, the %T/C values were 163%.

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Comparison with various mulberry leaves' and fruit's extract in lipid accumulation inhibitory effect at adipocyte model

  • Kim, Hyun-bok;Lim, Jung Dae;Kim, Ae-Jung;Kim, Yong-Soon;Kwon, O-Chul
    • International Journal of Industrial Entomology and Biomaterials
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    • 제35권1호
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    • pp.1-6
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    • 2017
  • In relation to the global increase trend of obesity population, there is a demand for the development of foods having high functional activity by mass-extracting anti-obesity active substances using mulberry product such as leaf and fruit. Therefore, we evaluated the antiobesity efficacy according to varieties by using the mulberry leaves and fruit extracts. At the same time, high active varieties were selected. For this purpose, the effects of the extracts of the mulberry leaf and fruit on 3T3-L1 adipocyte differentiation were examined. As a result, in the case of mulberry leaves, the lipid accumulation inhibitory rate of 'Cheongolppong' was higher than that of the control at $500{\mu}g/ml$ treatment. And in the case of the extract of mulberry fruit, 'Daesim' showed the highest lipid accumulation inhibitory rate compared with the control at 50 times of diluted extract.

틸팅차량용 탄소섬유직물/에폭시 복합재의 모우드 II 층간파괴인성 평가 (Evaluation of Mode II Interlaminar Fracture Toughness for Carbon Fabric/Epoxy Composite for Tilting Train)

  • 이은동;윤성호;신광복;정종철
    • 한국복합재료학회:학술대회논문집
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    • 한국복합재료학회 2004년도 추계학술발표대회 논문집
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    • pp.189-192
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    • 2004
  • In this study, mode II interlaminar fracture phenomena of carbon fabric/epoxy composite for tilting train were investigated. The end notched flexural specimen containing an artificial crack with the thickness of 12.5fl11l was used. The mode II interlaminar fracture toughness was evaluated through a three point bending test and the fractured surfaces were examined through a scanning electron microscope. The experimental results obtained in this study would be applicable in the design and structural analysis of the composite structures.

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