International Journal of Industrial Entomology and Biomaterials

Korean Society of Sericultural Science (한국잠사학회)
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Comparison with various mulberry leaves' and fruit's extract in lipid accumulation inhibitory effect at adipocyte model

  • Received : 2017.05.12
  • Accepted : 2017.07.04
  • Published : 2017.09.30
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Abstract

In relation to the global increase trend of obesity population, there is a demand for the development of foods having high functional activity by mass-extracting anti-obesity active substances using mulberry product such as leaf and fruit. Therefore, we evaluated the antiobesity efficacy according to varieties by using the mulberry leaves and fruit extracts. At the same time, high active varieties were selected. For this purpose, the effects of the extracts of the mulberry leaf and fruit on 3T3-L1 adipocyte differentiation were examined. As a result, in the case of mulberry leaves, the lipid accumulation inhibitory rate of 'Cheongolppong' was higher than that of the control at $500{\mu}g/ml$ treatment. And in the case of the extract of mulberry fruit, 'Daesim' showed the highest lipid accumulation inhibitory rate compared with the control at 50 times of diluted extract.

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References

  1. Hong SH, Kim DK, Lee NJ, Cho JH, Kang JK, Kim YB et al. (2005) Anti-obesitic effect of mulberry root-bark (Mori radicis Cortex) in Zucker Rats with high lipid diet induced-obesity. Korean J Clin Lab Sci 37(2), 129-137.
  2. Jun DY, Lee JY, Han CR, Kim KP, Seo MC, Nam MH et al (2014) Pro-apoptotic and anti-adipogenic effects of Proso Millet (Panicum miliaceum) Grains on 3T3-L1 preadipocytes. J Life Sci 24(5), 505-514. https://doi.org/10.5352/JLS.2014.24.5.505
  3. Ju WT, Kim HB, Kim KY, Sung GB, Kim YS (2015) Screening of 1-deoxynojirimycin (DNJ) producing bacteria using mulberry leaf. Int J Indust Entomol 31(2), 48-55. https://doi.org/10.7852/ijie.2015.31.2.48
  4. Ju WT, Kim HB, Sung GB, Kim YS (2016) Comparison of optimal temperature and time conditions for highest a-glucosidase inhibitory activity from various of Korea mulberry teas. Int J Indust Entomol 33(1), 31-35. https://doi.org/10.7852/ijie.2016.33.1.31
  5. Kim HB, Kim JB, Kim SL (2005) Varietal analysis and quantification of resveratrol in mulberry fruits. Korean J Seric Sci 47(2), 51-55.
  6. Kim HB, Kim JB, Kim SL, Koh SH, Seok YS, Kim YS et al (2011) Quantitative analysis of resveratrol in mulberry leaves. Korean J Corp Sci 56(1), 23-28. https://doi.org/10.7740/kjcs.2011.56.1.023
  7. Kim HB, Kim JB, Kim SL, Seok YS, Sung GB (2012) Seasonal resveratrol contents of wild-type mulberry leaves collected from Gangwon province in Korea. J Seric Entomol Sci 50(1), 10-14. https://doi.org/10.7852/jses.2012.50.1.10
  8. Kim HB, Kim SL (2003) Identification of C3G(cyanidin-3-glucoside) from mulberry fruits and quantification with different varieties. Korean J Seric Sci 45(2), 90-95.
  9. Kim HB, Kim SL (2004) Quantification and varietal variation of rutin in mulberry fruits. Korean J Seric Sci 46(1), 1-5.
  10. Kim HB, Kim SL, Kang SW (2004) Varietal analysis and quantification of amino acid in mulberry fruits. Korean J Seric Sci 46(2), 47-53.
  11. Kim HB, Kim SL, Lee SH, Sung GB, Seok YS, Kim YS et al. (2014a) Quantitative analysis of rutin with mulberry leaves (II). J Seric Entomol Sci 52(2), 129-133. https://doi.org/10.7852/JSES.2014.52.2.129
  12. Kim HB, Kim SL, Seok YS, Lee SH, Jo YY, Kweon HY, Lee KG (2014b) Quantitative analysis of rutin with mulberry leaves (I). J Seric Entomol Sci 52(1), 52-58. https://doi.org/10.7852/jses.2014.52.1.52
  13. Kim HB, Kim SL, Sung GB, Nam HW, Chang S, Moon JY (2003) Quantification and varietal variation of fatty acids in mulberry fruits. Korean J Seric Sci 45(2), 75-79.
  14. Kim HB, Seo SD, Koo HY, Seok YS, Kim SL, Sung GB (2013) Quantitative analysis of 1-deoxynijirimycin in mulberry leaves. J Seric Entomol Sci 51(1), 20-29. https://doi.org/10.7852/jses.2013.51.1.20
  15. Ko JH, Jeon WJ, Kwon HS, Yeon SW, Kang JH (2015) Anti-obesity effects of ethanolic extract of Polygonatum sibiricum Rhizome in high-fat diet-fed mice. Korean J Food Sci Technol 47(4), 499-503. https://doi.org/10.9721/KJFST.2015.47.4.499
  16. Kwon OJ (2016) Anti-adipogenic effect of Mori Follium extract in 3T3-L1 cells. Kor J Herbol 31(5), 47-53. https://doi.org/10.6116/KJH.2016.31.5.47.
  17. Lee SI, Lee YK, Lee IA, Choi JK, Kim SD, Suh JW (2013) Effects of mulberry leaf tea fermented by Monascus pilosus on body weight and hepatic antioxidant enzyme activities in mouse fed high fat diet. Korean J Food & Nutr 26(1), 66-77. https://doi.org/10.9799/ksfan.2013.26.1.066
  18. Park JI, Kang KH, Park EJ (2013) The study on anti-obesity effects of mulberry leaves contained herbal mixture. J Pediatr Korean Med 27(4), 17-30. https://doi.org/10.7778/jpkm.2013.27.4.017
  19. Sun XF, Yamasaki M, Katsube T, Shiwaku K (2015) Effects of quercetin derivatives from mulberry leaves: Improved gene expression related hepatic lipid and glucose metabolism in short-term high-fat fed mice. Nutr Res Pract 9(2), 137-143. https://doi.org/10.4162/nrp.2015.9.2.137
  20. Yun SJ, Lee WC (1995) Studies on the utilization of pharmacologically active constituents in mulberry 1. varietal and seasonal variations of flavonol glycoside content in leaves. RDA J Agri Sci 37, 201-205.
  21. Valacchi G, Belmonte G, Miracco C, Eo HY, Lim YS (2014) Effect of combined mulberry leaf and fruit extract on liver and skin cholesterol transporters in high fat diet-induced obese mice. Nutr Res Pract 8(1), 20-26. https://doi.org/10.4162/nrp.2014.8.1.20
  22. Wu YX, Kim YJ, Li S, Yun MC, Yoon JM, Kim JY et al (2015) Antiobese effects of mulberry (Morus alba L.) root bark through the inhibition of digestive enzymes and 3T3-L1 adipocyte differentiation. Korean J Food Preserv 22(1), 27-35. https://doi.org/10.11002/kjfp.2015.22.1.27
  23. Yang SJ, Park NY, Lim YS (2014) Anti-adipogenic effect of mulberry leaf ethanol extract in 3T3-L1 adipocytes. Nutr Res Pract 8(6), 613-617. https://doi.org/10.4162/nrp.2014.8.6.613

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