• 대한한의학방제학회지
• /
• 제17권1호
• /
• pp.45-59
• /
• 2009

To beef up natural immunity, we have used Bojoongikgitang which has been known to treat enervation in the oriental medicine. This study is analyzed out structure material and the chief virtue of a prescription through Literature Study on Bojoongikgitang and Clinical Application. And this study is investigated to make sure of the necessity and additional symptoms in using Bojoongikgitang. The results are as follows : 1. It is regarded that the structure materials of Bojoongikgitang consist of Astragali Radix one jeon(錢) five poon(分), Ginseng Radix, Atractylodis Macrocephalae Rhizoma, Glycyrrhizae Radix one jeon for each, Citri Pericarpium, Angelicae Gigantis Radix five poon for each, Cimicifugae Rhizoma, Bupleuri Radix three poon for each. 2. The necessity symptoms in using Bojoongikgitang are a pale complexion, drowsy eyes(目無精光), vigorless, lethargy, sluggish talk. 3. The fittest prescriptions prior to the necessity symptoms in using Bojoongikgitang are Bojoongikgitang added Paeoniae Radix Alba, Scutellariae Radix in fever, exterior heat, mild fever, Bojoongikgitang added Ephedrae Radix, Tritici Fructus Levis, Aconiti Iateralis Preparata Radix in spontaneous sweating, spontaneous sweating by yang deficiency, Bojoongikgitang added Paeoniae Radix Alba, Scutellariae Radix in feeling the pulse like a flood, largeness and weakness, scatter and largeness, flood and largeness for diagnosis respectively. Bojoongikgitang Entering the heart channel by culturing the blood prescription in vexation, vexation and anxiety, Soongihwajoongtang in headache, DossiBojoongikgitang in rigor, Bojoongikgitang annexed Saengmaecsan in thirst, Daninsamtang or Jojoongikgitang in asthma, asthma by congestion of the upwardness, Eeegongsan in light eating, eschewing food, losing one's appetite, Ikweeseungyangtang in deficiency failing to control blood and blood collapsey. 4. To treat a functional disease is superior to organic one in using Bojoongikgitang.

• 동국한의학연구소논문집
• /
• 제9권
• /
• pp.51-71
• /
• 2000

본 실험은 월국환합보중익기탕(越鞠丸合補中益氣湯)의 항스트레스효과를 조사하기 위하여 시행되었다. 월국환합보중익기탕(越鞠丸合補中益氣湯)이 전기자극으로 스트레스 상황을 유발시킨 mouse에게 끼친 B 임파구 면역계 변화를 mouse 혈청의 면양적혈구(綿羊赤血球)에 대한 적혈구 응집소가와 비장세포에서 B 세포 및 T 세포가 차지하는 백분율의 변화를 통하여 측정하였으며 이를 대조군과 비교 분석하였다. 혈청 항체가의 측정에서 스트레스 자극하에서 월국환합보중익기탕(越鞠丸合補中益氣湯)을 투여받은 그룹에서 약제를 투여받지 않은 그룹에 비하여 유의성 있는 차이를 보여(p<0.01) 면역 기능을 정상군의 수준으로 유지하는 결과를 얻었다. T 세포와 B 세포의 백분율의 측정에서도 스트레스 자극하에서 월국환합보중익기탕(越鞠丸合補中益氣湯)을 투여 받은 그룹에서 약제를 투여 받지 않은 그룹에 비하여 유의성 있는 차이를 보여(p<0.01) 면역 기능을 정상군의 수준으로 유지하는 결과를 얻었다. 실험결과들로 보아 월국환합보중익기탕(越鞠丸合補中益氣湯)이 체액성 면역 반응과 비장 내 면역 세포의 백분율을 정상의 수준으로 유지하는 효과를 보여 면역 기능의 이상에 응용할 수 있는 가능성을 제시한다고 사료된다.

• 대한예방한의학회지
• /
• 제18권1호
• /
• pp.53-65
• /
• 2014

The concentration of 5 metals such as As, Cd, Co, Cr and Pb in 5 frequent using herbal medicinal prescriptions in Korea were analyzed according to the consuming area. The ready prepared 5 prescription samples were obtained from Korean regional hospitals nationwide. All the sample were well powdered and pre-treated to being a solution, and then analyzed by ICP/MS. As was detected the highest concentration of 0.55 mg/kg in Ojeoksan of Gyunggi-do, the lowest was 0.01 mg/kg of Sipjeondaebotang of Seoul C. The highest concentration of Co was found to be in Bojoongikgitang of Seoul B and the lowest was also detected in Bojoongikgitang of Seoul A. Cd concentration, Ojeoksan of Chungcheong-do, Bojoongikgitang of Seoul B and yookmijihwangtang of Chungcheong-do showed the low level of 0.1 mg/kg. In turn, the highest level of Cr was 5.59 mg/kg in Ojeoksan of Gyunggi-do B. The lowest concentration of Cr was 0.04 mg/kg in Sipjeondaebotang of Seoul C and the highest was 0.94 mg/kg in Samooltang of Gangwon-do. Finally, the lowest concentration of Pb was 0.00 mg/kg in Sipjeondaebotang of Chungcheong-do and the highest was 0.134 mg/kg in Ojeoksan of Jeju-do. As a result it seems that the same prescription can not guaranteed the safety from toxic metals since those metal concentrations are dramatically varied according to the area where the each prescribed medicine available.

• 대한한의학방제학회지
• /
• 제18권2호
• /
• pp.1-14
• /
• 2010

This report describes 57 prescriptions including Paeoniae Radix and Glycyrrhizae Radix in Dongeuibogam. Paeoniae Radix and Glycyrrhizae Radix have been used separately or concurrently in Oriental Medicine for a long time as a treatment for various disease. The following conclusions are reached through investigations on the applications of prescriptions including Paeoniae Radix and Glycyrrhizae Radix in Dongeuibogam. 1. 7 times(12.3%) prescriptions are recorded in women chapter, 6 times(10.5%) in cold chapter, 5 times(8.8%) in stool chapter and fatigue chapter each, 4 times(7.0%) in psychiatry chapter, which are arranged in order of frequency. 2. Anxiety, Yin-Yang deficiency, stroke, treating blood, cataract, fever floating due to Yin deficiency, weak and fatigue, pregnancy, abortion, women accessary disease, cold-feeling heart pain, stiffness, etc, among 51 symptoms in prescriptions including Paeoniae Radix and Glycyrrhizae Radix. 3. The dosage of Paeoniae Radix and Glycyrrhizae Radix are from 5 pun:2.5 pun to 2 nyang:1 nyang. 1 jeon:5 pun is recored 39 times(68.4%), 2 jeon:1 jeon and 1 nyang:5 jeon is 6 times(3.21%), 2 nyang:1 nyang is 2 times(1.8%) used among 57 prescriptions including Paeoniae Radix and Glycyrrhizae Radix. 4. 57 prescriptions including Paeoniae Radix and Glycyrrhizae Radix are mostly composed of Samooltang and Sagoonjatang, Gyejitang, Gamgiltang, Bowontang, Goongguitang, Jeongwoneum, Bojoongikgitang, Jigoongsan, Ijintang, Pyeongwuisan, Oryungsan, etc, according to the usage.

• 대한예방한의학회지
• /
• 제19권3호
• /
• pp.103-113
• /
• 2015

Objective : Five most generally adopting basic oriental prescriptions (yookmijihwangtang, ojeoksan, sipjeondaebotang, samultang, bojoongikgitang) samples were collected from 10 oriental hospitals nationwide and the transferring ratio to aqueous phase (TRAP) were calculated. Method : The samples are grounded evenly and the decocted at $120^{\circ}C$ for 12 min on hot plate and then filtered. The concentrations of As, Cd, Co, Cr and Pb in before and after decoction were measure by ICP/MS and the TRAPs were calculated. Results : The concentrations of As, Cr and Pb in the ground samples before decoction were all below criteria level, and TRAP values were also very low (<10%). For Cd, although some ground samples before decoction showed relatively high concentration level compare to the criteria level, because of their low TRAP (~3%), the actual concentrations in the decoction were quite low compare the criteria level. The Co's concentrations in the ground samples before decoction were all relatively low level. However, the TRAP of Co was astonishingly high value of around 40% average. Conclusion : The toxic heavy metal concentrations in the decoction were very low compare to the criteria level. The TRAPs are less than <10% except Co. The toxic heavy metals in the prescriptions are mainly remained in the residue and the only very small fraction may transferred to the decoctions. Therefore the toxicity of the oriental herbal medicine about the toxic heavy metal may be overstressed. The Co's TRAP turned out to be quite high value (40% average). Since the criteria level wes not established yet, the safety of decoctions according to Co was not fully confirmed.