• The korean journal of orthodontics
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• v.18 no.2
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• pp.329-342
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• 1988

In methods of finding causes for cleft palate, many cases have been studied by investigators using teratogenic agents. Among them, a synthetic agent known as triamcinolone acetonide (TA) was widely used. When this drug was injected into mice during palatogenesis, it induced lowered body weight and a deformed mandible. But many cases have been studied on growth changes, only of the developmental stages of the palate. Therefore, the objective of this study was to evaluate craniofacial growth in experimentally induced cleft palate mice after finishing palatogenesis namely just before birth. Normal, alcohol treated, and TA treated DDY mice were obtained at 18-days of gestation and heads were prepared for serial sectioning in the sagittal plane. The midsagittal sections were photographically enlarged (${\times}40$) and measurements made to asses the amount of growth. The obtained results were as follows. 1. The incidence of cleft palate was 41.2% when TA was injected. 2. The body weight of the cleft palate group was lower than the control group. 3. In the cleft palate group, mandibular length (H-M) was lighter than the control group. 4. In the cleft palate group, degree of staining was not distinct compared to the control group by the double staining method. 5. In the cleft palate group, anteroposterior posture of the tongue tip to facial plane (C-M) was more posterior than the control group. 6. The cause of posterior posture of the tongue tip to facial plane (C-M) in the cleft palate group, was not short and retracted tongue but the mandibular length was increased. 7. The anteroposterior relationship of hyoid cartilage to cranial base was the same in all groups.

• Asian-Australasian Journal of Animal Sciences
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• v.5 no.4
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• pp.665-671
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• 1992

To investigate the effects of immunization against somatostatin (SRIF) on growth rate, feed efficiency and carcass quality; forth-eight Yorkshire gilts ($age=37.5{\pm}4.3d,\;wt=8.2{\pm}1.6kg$) were randomly assigned to one of the following three treatments (1) control, (2) bovine serum albumin (BSA) and (3) SRIF. Cyclic SRIF was conjugated to BSA as the antigen containing 1 mg of SRIF diluted in 3 ml of saline. The conjugate was injected subsutaneously together with bacterial cell protein (BP) adjuvant on both sides of the neck of each gilt as the initial injection with three subsequent booster injections. Throughout the experiment all pigs were fed ad libitum a corn-soy diet containing 20% protein. Body weight and feed intake were measured on a weekly basis. All pigs in the experiment were slaughtered when they approached 101 kg body weight on the weekly weigh day. After slaughter, carcass parameters were analyzed to assess carcass quality. Results revealed that there were no differences among SRIF, BSA and control treatments for average daily gain, feed efficiency and feed intake during the first 5 wk of the experiment and from 6 wk to slaughter. The results for carcass analysis indicated that active immunization against SRIF had no effect on fat content, lean yield, water content and Canadian carcass index These data, collectively, suggest that the protocol employed in the present investigation for active immunization against SRIF is not an effective method for the enhancement of pig growth and improvement of feed efficiency and carcass quality.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.2
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• pp.198-205
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• 2017

Objective: This study aimed to investigate the effects of single or/and double strains of probiotic supplement on feed efficiency, growth performance, and microbial population in distal gastrointestinal tract (GIT) of weaning rabbits. Methods: Sixty-four weaning (28 days old) New Zealand White rabbits were randomly distributed into four groups with treatments including: basal diet without probiotic supplement (control) or supplemented as follows: $1{\times}10^6cfu/g$ B. subtilis (BS group), $1{\times}10^7cfu/g$ L. acidophilus (LA group), or $0.5{\times}10^6cfu/g$ B. subtilis plus $0.5{\times}10^7cfu/g$ L. acidophilus (BL group). During the research, the male and female rabbits were fed separately. Body weight of the rabbits was recorded at 28, 42, and 70 d of age. Results: There was an increase (p<0.05) in body weight gain for the LA group at 42 d. Rabbits fed BL responsed with a greater growth (p<0.05) and better feed conversion ratio (p<0.05) than those fed with no probiotic. Digestibility coefficients of dry matter, organic matter, crude protein, neutral detergent fiber, and gross energy were higher (p<0.05) in LA and BL groups than those in the control group. Male rabbits had higher (p<0.05) Bacilli spp. and Coliformis spp. in the ileum than female rabbits. Rabbits supplemented with BS had greater (p<0.05) numbers of bacilli in all intestinal segments than those receiving no probiotic, whereas intestinal Lactobacilli populations were greater (p<0.001) in the LA and BL diets compared to control. Average intestinal coliform populations were lowest (p<0.05) in the rabbits supplemented with LA as compared to those fed the control and BS. Conclusion: Supplementation of L. acidophilus alone or in combination with B. subtilis at a half of dose could enhance number of gut beneficial bacteria populations, nutrient digestibility, cecal fermentation, feed efficiency, and growth performance, but rabbits receiving only B. subtilis alone were not different from the controls without probiotic.

• Korean Journal of Veterinary Service
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• v.33 no.4
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• pp.387-392
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• 2010

This experiment was conducted to investigate the effect of fermented spent mushroom substrate (FSMS) on growth performance, blood profile, intestinal microflora and ammonia gas production of feces in broiler chickens. A total of three hundred sixty, 1-day-old male broiler chicks (Ross) were randomly divided into 3 groups with 6 replicates of 20 birds each. The treatments were control (free FSMS), 15% FSMS (basal diet with 15% FSMS) and 30% FSMS (basal diet with 30% FSMS). The final body weight and body weight gains were slightly improved in 30% FSMS than control (P<0.05). Feed intake and feed conversion were significantly improved as compared to those of the control groups. The Leukocytes of blood serum in FSMS groups were significantly decreased as compared to those of control groups. There are no significant differences among the groups in the contents of albumin (ALB), total cholesterol (TCHO), glucose (GLU), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in blood serum. The content of total glucose (TG) in 30% FSMS containing dietary groups was significantly decreased as compared to that of the control groups. The content of HDLC in 30% FSMS containing dietary groups was significantly increased as compared to that of the control group. The number of lactobacillus in the intestinal microflora were significantly increased in chicks fed FSMS groups. The ammonia gas production in FSMS groups was siginificantly decreased as compard to that the control groups. These results indicated that dietary FSMS exerted growth performance for feeding broiler.

• Microbiology and Biotechnology Letters
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• v.47 no.4
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• pp.509-514
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• 2019

We investigated the beneficial effects of Ecklonia cava by-product (ECB), a residual product obtained after polyphenol extraction from Ecklonia cava, on normal rats. Male Sprague-Dawley rats were divided into the following three groups: Control group (NC), received basal diet; ECB 0.1 group, received basal diet supplemented with 0.1% ECB for 21 days; ECB 0.5 group, received basal diet supplemented with 0.5% ECB for 21 days. The productivity, serum immunoglobulin level, expression levels of muscle-related genes, and cecal microflora were measured in all the treatment groups to evaluate the potential use of ECB as a feed additive. The ECB 0.1 group exhibited enhanced expression of Myod, Myog, and Igf1 genes, which increased the body weight of rats. Additionally, treatment with ECB increased the cecal Lactobacillus spp. counts and the serum immunoglobulin G levels in rats. Thus, ECB can effectively increase body weight and can be a potential feed additive for improving growth.

• Korean Journal of Agricultural Science
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• v.46 no.4
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• pp.705-713
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• 2019

This study was conducted to determine the effects of dietary non-genetically modified organism (non-GMO) wheat-based diets on the growth performance, nutrient digestibility, blood profile and meat quality of grower-finisher pigs. A total of 70 [(Landrace × Yorkshire) × Duroc] growing pigs with an initial body weight of 26.15 ± 1.57 kg were used in a 112 day trial. The dietary treatments were as follows: (I) CD, corn-based diet and (II) non-GMO WD, a non-genetically modified organism wheat-based diet. Each treatment consisted of 7 replicate pens with 5 pigs per pen. In the current study, the pigs fed the corn-based diet had a higher body weight than the pigs fed the non-GMO wheat-based diet at day 21 and day 77 (p < 0.05). There was a significant difference in the average daily gain (ADG) during the first 21 days (p < 0.05). The non-GMO wheat-based diet had no effect on nutrient digestibility. In addition, the non-GMO wheat-based diet had no effect on the blood profile except for blood urea nitrogen (BUN) at d 21. In conclusion, the non-GMO wheat-based diet only had a slight effect on the growth performance of growing pigs but had no significant impact on the nutrient digestibility, fecal score, blood profile and meat quality of the pigs during the grower-finisher period.

• Korean Journal of Agricultural Science
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• v.44 no.2
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• pp.228-234
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• 2017

Feed intake (FI) of sows during lactation is a serious problem because sows require a large amount of energy for high milk production during lactation. Providing a palatable diet is important for lactating sows to cope with the stress of breast-feeding. Palatability can be increased by adding sweeteners to diets. This study was conducted to evaluate the effects of saccharin (sweetener) on growth performance, fecal moisture, and litter performance of lactating sows. Sixteen sows were randomly allotted to one of two dietary treatments in a 27-day trial starting from lactation. The two dietary treatments were supplemented with 0 and 0.2% saccharin (sweetener), respectively. Average daily feed intake (ADFI) was increased (p < 0.05) and back fat loss (BFL) was decreased (p < 0.05) in sows fed saccharin supplementation diets compared with sows fed control diet during lactation. However, sows' body weight loss, body condition score (BCS), fecal score, and the number of piglet survival were not different (p > 0.05) among dietary treatments. The two dietary treatments also had no significantly different effect (p > 0.05) on litter weight and average daily gain (ADG) of piglets. Taken together, saccharin has no significant effect on growth performance of piglets but it can increase FI and reduce BFL of lactating sows.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.40 no.6
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• pp.380-386
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• 2007

Egg development and juvenile growth of the Pacific cod Gadus macrocephalus (Korean East Sea Population) were studied to increase fry production using mass cultivation. The eggs were rectangular and adhesive sinking type. The egg size and fertilization rate were 1.01-1.09 mm and 72.4%, respectively. The cumulative times for egg hatching at 3, 6, 9, and $12\;^{\circ}C$ were 600, 360, 240, and 192 hrs, respectively. The hatching rates at 3, 6, 9, and $12\;^{\circ}C$ were 60.2, 68.9, 62.5, and 40.6%, respectively. After 11, 45, and 90 days, the larvae grew to a total length of 5.46-5.99, 9.42-10.06, and 23.0-32.0 mm, respectively. At 100 days from hatching, they grew to an average of 30 mm with a 7.1 % survival rate. By 312 days, juveniles with a total length of 3.6 cm grew to a total length of 14.7-20.1 cm and a body weight of 38.4-73.9 g. The specific growth rates of total length and body weight of the juveniles were 0.50% and 1.12%, respectively.

• Journal of Oral Medicine and Pain
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• v.42 no.4
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• pp.109-115
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• 2017

Purpose: This study analyzed the effects of digastric muscle injury on mandibular growth in young rats. Methods: Fourteen 4-week-old Wistar rats were divided into 3 groups; experimental group A (n=6) with unilateral (right) shortening of the posterior digastric muscle, experimental group B (n=6) with bilateral shortening of the posterior digastric muscles, and control group C (n=2) who underwent a sham operation. Eight weeks after the operation all animals were sacrificed and the outcomes were compared using body weight evaluation, mensurations on lateral radiograph of hemimandibles and histological evaluation. Results: There was no significant difference between groups A and B in body weight gain. Comparison of the mean values of hemimandible distance on radiograph was performed. The difference in group mean value of mandible-related distances was analyzed using the Wilcoxon test (rank sum test) and a comparison of the homonymous distances of group A and B was performed using the Mann-Whitney test. There were differences between sides in mandibular length in group B and mandibular ramus height and transverse width of the condyle in group A (all, p<0.05). There were differences in condylar height and mandibular length on the left side between groups A and B (p<0.05). Histologic examination of temporomandibular joint showed similar findings in all specimens. Conclusions: Injury of the posterior belly of the digastric muscle during the rat growth period induced shortening of mandibular ramus height and transverse width of the condyle. It can be inferred that trauma to the posterior belly of the digastric muscle affects horizontal and vertical growth of the mandible.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.45 no.6
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• pp.648-653
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• 2012

The present study examined the effects of dietary supplementation with nucleotide (inosine monophosphate product, IMP) on the growth performance, feed utilization, and non-specific immune responses of juvenile tilapia Oreochromis niloticus. Triplicate groups of tilapia (initial body weight, $7.4{\pm}0.04$ g) were fed experimental diets containing 0%, 0.05%, 0.1%, and 0.2% IMP. Fish were fed six times a day until apparent satiation for 13 weeks. At the end of the feeding trial, final body weight and food utilization of fish fed 0.1% IMP were significantly higher than those of fish fed the control diet. Results of hematological parameters were not affected by dietary IMP. However, blood protein level was significantly higher in the 0.05% treatment, as compared to that of the control and 0.2% IMP diets. Myeloperoxidase activity was higher in fish fed 0.1% IMP than in fish fed the control and 0.2% IMP diets. These results suggest that dietary supplementation with IMP can enhance the growth performance, feed utilization, and innate immune response of juvenile tilapia. The optimal IMP supplementation level appears to be 0.1% in practical feed formulations for tilapia.