• 한국시뮬레이션학회:학술대회논문집
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• 한국시뮬레이션학회 2005년도 춘계학술대회 논문집
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• pp.149-153
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• 2005

In the cardiovascular system, the waveform of the pulsatory blood pressure appears variously due to the cardiac impulse and compliance of blood vessels and arm tissue. We have constructed a blood pressure simulator to investigate effects of mechanical properties of artery walls and tissue on blood pressure measurements. The blood pressure simulator is designed to reproduce wave forms of blood pressure in human arteries. To minimize tracking error, we use a linear control valve, and adapt a hybrid control scheme which consists of a feedback controller and a feedforward controller. Any form of the pressure wave can be reproduced, changing function of the wave form in the computer connected to the simulator for control. From experiments, it has been shown that the simulator reproduces wave forms very well, and that the hybrid scheme adapted is superior to the feedback controller.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제16권4호
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• pp.1209-1223
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• 2022

Blood pressure is one of the key physiological parameters for determining human health, and can prove whether human cardiovascular function is healthy or not. In general, what we call blood pressure refers to arterial blood pressure. Blood pressure fluctuates greatly and, due to the influence of various factors, even varies with each heartbeat. Therefore, achievement of continuous blood pressure measurement is particularly important for more accurate diagnosis. It is difficult to achieve long-term continuous blood pressure monitoring with traditional measurement methods due to the continuous wear of measuring instruments. On the other hand, radar technology is not easily affected by environmental factors and is capable of strong penetration. In this study, by using machine learning, tried to develop a linear blood pressure prediction model using data from a public database. The radar sensor evaluates the measured object, obtains the pulse waveform data, calculates the pulse transmission time, and obtains the blood pressure data through linear model regression analysis. Confirm its availability to facilitate follow-up research, such as integrating other sensors, collecting temperature, heartbeat, respiratory pulse and other data, and seeking medical treatment in time in case of abnormalities.

• 동의생리병리학회지
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• 제25권3호
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• pp.551-557
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• 2011

The purpose of this study is to investigate the relation between brachial-ankle pulse wave velocity and the features of metabolic syndrome, and differences according to sex in patients diagnosed cerebral infarction. The study group comprised 61 patients over age 30 who were diagnosed cerebral infarction, accompanied with metabolic syndrome. The brachial-ankle pulse wave velocity, blood pressure, lipid profiles, fasting blood glucose, body mass index were measured. Also we checked past history of patients. Then we analyzed the association between brachial-ankle pulse wave velocity and the features of metabolic syndrome. Pearson correlation analysis reflected the variables affecting the brachial-ankle pulse wave velocity as follows : Age, SBP(systolic blood pressure), DBP(diastolic blood pressure), FBS(fasting blood glucose) were positively correlated. As a result of regression analysis, in patients with cerebral infarction accompanied with metabolic syndrome, the brachial-ankle pulse wave velocity is affected by age to men, SBP, FBS, DBP to women. The brachial-ankle pulse wave velocity is not affected by the components of metabolic syndrome, except blood pressure, FBS, in patients with ischemic stroke.

• 센서학회지
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• 제20권5호
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• pp.343-350
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• 2011

The compliance and stiffness of artery are closely related with disease of arteries. Pulse wave velocity(PWV) in the blood vessel is a basic and common parameter in the hemodynamics of blood pressure and blood flow wave traveling in arteries because the PWV is affected directly by the conditions of blood vessels. However, there is no standardized method to measure the PWV and it is difficult to measure. The conventional PWV measurement has being done by manual calculation of the pulse wave transmission time between coronary arterial proximal and distal points on a strip chart on which the pulse wave and ECG signal are recorded. In this study, a pressure sensor consisting of strain gauges is used to measure the blood pressure of arteries in invasive method and regular ECG electrodes are used to record the ECG signal. The R-peak point of ECG is extracted by using a reference level and time windowing technique and the ascending starting point of blood pressure is determined by using differentiation of the blood pressure signal and time windowing technique. The algorithm proposed in this study, which can measure PWV automatically, shows robust and good results in the extraction of feature points and calculation of PWV.

• 대한한의진단학회지
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• 제16권1호
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• pp.19-26
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• 2012

Objectives The aim of this study is to develop a cardiovascular simulator that can reproduce blood pressure pulse and blood flow similar to those of the human body. Methods In order to design a system similar to the human cardiovascular system, the required performances were determined by investigating the hemodynamic characteristics of the heart and the arterial system. Main organ to be imitated is heart in simulator. The rest of the system was minimally designed. Also, a blood pressure and blood flow measurement system was developed for measuring the results. Results The developed system showed blood pressure pulse at similar range of the human aorta. The result waveform include primary wave caused by ventricular systole except reflected wave. Conclusions The blood pressure and blow flow patterns were replicated by the simulator. These patterns were similar to those of the human body. The system will play an important role in studying pulse diagnostics.

• 대한의용생체공학회:의공학회지
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• 제36권5호
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• pp.183-190
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• 2015

Invasive blood pressure (IBP) is measured for the patient's real time arterial pressure (ABP) to monitor the critical abrupt disorders of the cardiovascular system. It can be used for the estimation of cardiac output and the opening and closing time detection of the aortic valve. Although the unexplained inflections on ABP make it difficult to find the mathematical relations with other cardiovascular parameters, the estimations based on ABP for other data have been accepted as useful methods as they had been verified with the statistical results among vast patient data. Previous windkessel models were composed with systemic resistance and vascular compliance and they were successful at explaining the average systolic and diastolic values of ABP simply. Although it is well-known that the blood pressure reflection from peripheral arteries causes complex inflection on ABP, previous models do not contain any elements of the reflections because of the complexity of peripheral arteries' shapes. In this study, to simulate a reflection wave of blood pressure, a new mathematical model was designed with four elements that were the impedance of aorta, the compliance of aortic arch, the peripheral resistance, and the compliance of peripheral arteries. The parameters of the new model were adjusted to have three types of arterial blood pressure waveform that were measured from a patient. It was used to find the relations between the inflections and other cardiovascular parameters such as the opening-closing time of aortic valve and the cardiac output. It showed that the blood pressure reflection can bring wide range errors to the closing time of aortic valve and cardiac output with the conventional estimation based on ABP and that the changes of one-stroke volumes can be easily detected with previous estimation while the changes of heart rate can bring some error caused by unexpected reflections.

• 한국자기학회지
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• 제20권3호
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• pp.106-113
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• 2010

비가압 상태에서 혈압 및 맥박을 정확하게 측정한 값를 얻기 위하여 안정시 휴대성과 소형화가 가능한 자성 홀소자를 이용한 손목 착용형 맥진기의 시제품을 개발하였다. 본 시제품을 이용하여 맥진파를 분석한 13명의 임상시험 데이터로 상관인자를 정하여 혈압추정 알고리즘의 회귀식을 구하였다. 5초간 비가압 맥진기로 맥진파를 수집한 혈압추정값과 전자혈압계나 수은혈압계로 측정한 혈압값을 비교하였다. 비가압 맥진기로 추정한 최고혈압과 최저혈압의 표준편차는 혈압국제규격 허용치 범위 안에 있는 12.1과 5.9로 각각 나타났다.

• 대한전기학회논문지:시스템및제어부문D
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• 제54권8호
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• pp.504-509
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• 2005

This paper presents a new method for obtaining the noninvasive and unrestrained blood pressure readings noninvasively and unrestrainedly using based on reflected wave arrival time(RAT) in the volume of pulse. Since this new method employs only volume pulse, is more rapider and simpler than the method using pulse transit time(PTT) because it only employs the volume of pulse. Blood pressure, PTT and RAT were acquired from 15 healthy subjects. Each subjects were performed forty trials of each measurement. As a result of those trials, the mean error between oscillometric and RAT measurements for systolic blood pressure was $4.55\pm5.64mmHg$. This result showed quite equal with the mean error between oscillometric and PPT measurf:ments, $4.22\pm5.30mmHg$, However, it was not obtained a satisfactory result in the relativity of oscillometric to both RAT and PPT measurements for diastolic blood pressure because of personal difference. To conclude, the method of systolic blood pressure estimation noninvasively and unrestrainedly using by RAT may be used as the method by PTT. Nevertheless, additional studies would be necessary for the RAT/PTT estimation of diastolic blood Pressure measurement.

• Current Optics and Photonics
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• 제1권5호
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• pp.529-537
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• 2017

We explored how changes in blood vessel compliance affected the systolic rise time (SRT) of the maximum blood pressure (BP) peak wave and the diastolic fall time (DFT) of the minimal BP peak wave, compared to photoplethysmograpic (PPG) parameters, using a two-compartment, second-order, arterial Windkessel model. We employed earlier two-compartment Windkessel models and the components thereof to construct equivalent blood vessel circuits, and reproduced BP waveforms using PSpice technology. The SRT and DFT values were obtained via circuit simulation, considering variations in compliance (the dominant influence on blood vessel parameters attributable to BP changes). And then performed regression analysis to identify how compliance affected the SRT and DFT. We compared the SRTs and DFTs of BP waves to the PPG values by reference to BP changes in each subject. We confirmed that the time-shift propensities of BP waves and the PPG data were highly consistent. However, the time shifts differed significantly among subjects. These simulation and experimental results allowed us to construct an initial trend curve of individual BP peak time (measured via wrist PPG evaluations at three arm positions) that facilitated accurate individual BP estimations.

• Transactions on Electrical and Electronic Materials
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• 제9권5호
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• pp.213-219
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• 2008

Pulse waves continuously change with respect to the characteristics and status of the cardiovascular system and in relation to the blood pressure (BP) and the pulse wave velocity (PWV). Monitoring the vascular condition by analyzing the variations in pulse waveforms has been used to diagnose vascular disorders and in drug treatment of arteriosclerosis and peripheral circulatory obstruction. In this paper, we investigated the vascular characteristic index with regard to the BP and classified by pulse wave signals. The pressure pulse wave and photoplethysmography (PPG) were measured simultaneously while subjects exercised, producing changes in the BP, to analyze the variation in the vascular characteristic index. We investigated the correlation between the BP and vascular characteristic index with regard to the classification methods of the pulse wave. The reflection index (RI) and vascular stiffness index were correlated with the diastolic BP, but no correlation was found between these parameters and the systolic BP. These results suggest the possibility of estimating BP through simple measurements of pulse waves.