• 제어로봇시스템학회:학술대회논문집
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• 1997.10a
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• pp.1643-1646
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• 1997

In this study, the method is proposed, which enable us to noninvasively assess baroreflex sensitivity through the closed-loop feedback modle between RR flucturarion and arterial blood pressure fluctuation. The proposed indexes of baroreflex sensitivity, BRS$_{LF}$와 BRS$_{HF}$ are calculated by the modulus (or gain) of the transfer function between fluctuatuons in blood pressure and RR interval in the LF band HF band, where the coherence is more than 0.5 to evaluate the performance of the proposed method, it is applied to various cardiovascular variability signals obtained form subjects under the submaximal ecericse on bicycle ergometner. In result it is concluded that the proposed method can noninvasively assess the baroreflex sensitivity.ty.

• Journal of Integrative Natural Science
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• v.12 no.3
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• pp.74-77
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• 2019

The purpose of this study is to explore the effects of Chamaecyparis obtusa essential oil on the activity of autonomic nervous system. Heart rate variability (HRV), as an indicator of autonomic nervous system activity and blood pressure were measured before and after inhalation of Chamaecyparis obtusa essential oil. The systolic blood pressure was decreased by inhalation of Chamaecyparis obtusa essential oil (p<0.05). The diastolic blood pressure was not changed significantly by Chamaecyparis obtusa. High frequency (HF) power level was not changed but High frequency/Low frequency (HF/LF) ratio was decreased by Chamaecyparis obtusa essential oil (p<0.05), meaning that parasympathetic nervous system activity was not affected but sympathetic nervous system activity was decreased. These results indicate that Chamaecyparis obtusa essential oil has a modulatory effect on the autonomic nervous system activity.

• Korean Journal of Adult Nursing
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• v.26 no.3
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• pp.341-351
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• 2014

Purpose: The purpose of the study was to examine preventive effects of tailored water drinking on orthostatic hypotension and heart rate variability in the elderly. Methods: A non-equivalent control group pre and post time-series design was adapted. Among a total of 64 elderly people admitted to two nursing homes, 35 elderly were assigned to the experimental group and 29 were assigned to the control group. As for the elderly people in the experimental group, tailed water drink was provided according to the scheduled time for six weeks. Blood pressure and heart rate were measured twice before the intervention in both groups. The data were analyzed with SPSS program using t-test, ${\chi}^2$-test, and repeated measure of ANOVA. Results: There were significant differences in blood pressure and heart rate variability between the two groups. Conclusion: Tailored water drinking had preventive effects on decreasing blood pressure fall as well as prevalence of orthostatic hypotension in the elderly people.

• Journal of the Ergonomics Society of Korea
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• v.30 no.1
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• pp.237-250
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• 2011

The train transportation has a lot of advantages-energy efficiency is high, it is eco-friendly, safety is better than normal roads and it is possible for people to arrive on time. In these days, the valuation of ride comfort, which is only limited to road transportation, is newly recognized in order to having competitiveness from other transportation. Especially, in the development of the Korean high-speed railroad business, the ride comfort enhancement of train is very important problem to be solved. Currently, there are international standards of ride comfort such as UIC13, ISO2631. In Korea case, although it has own standard like KS R9216, it mainly depends on the physical parameter such as vibration and noise. So recently, in the valuation of ride comfort, the movements of living parameter technique introduction are increasing on the base of Japan and many developed countries of Europe techniques. Presently, the method of train ride comfort is mainly based of vibration, that is, mechanical parameter adding selection of variable acceleration and noise. This paper would like to show biological parameter; heart rate and blood pressure variation. This method is more direct, based on human body response, than mechanical parameter method. In this experiment, the variability of heart rate and blood pressure of passengers according to tilting angle change of Train, the Korean tilting train, we are supposed to know that the extent of tilting on the simulation has influence on variability of heart rate and blood pressure, which are living parameter of heart's blood.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.1
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• pp.109-118
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• 2022

Purpose : The study to verify the effectiveness of the Soomchi combined marine healing program by analyzing the physical composition of the subjects, their blood lipids, and the effects of the program on their lung health-related variables, and heart rate variability variables. Methods : In the experiment, the Soomchi combined marine healing program was conducted for 5 hours a day, 5 days a week. on 15 participants. The results of their body composition, blood lipids, lactic acid, blood pressure, PEF, FEV1 and maximum oxygen intake were analyzed before and after the subjects completed the Soomchi program. For the statistical analysis, the mean and standard deviation (M±SD) of each variable were calculated using SPSS version 20 and an independent t-test was conducted to test for the amount of change in the participants before and after the Soomchi combined marine healing program. All significant levels were set to α=.05. As a result of the experiment Results : First, no statistically significant differences were found in the changes in body composition after the 5-day combined marine healing program was completed. Second, regarding the changes in blood component after the program was conducted, statistically significant differences were found in the lactic acid (p<.05). That is, the experimental group showed a significant decrease in lactic acid after the program whereas the control group showed a significant increase. Third, systolic blood pressure decreased significantly and while in PEF and FEV1 increased significantly in the experimental group after the program. Fourth, the LF of the control group significantly decreased after 5 days. Conclusion : After the Soomchi Lung Health Ocean Healing Program, positive physical changes were observed in the lung health variables and heart rate variability of the participants.

• Journal of the East Asian Society of Dietary Life
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• v.9 no.3
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• pp.378-385
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• 1999

A reduced NaCl intake for the general population of the world has been recommended to reduce the overall blood pressure level and hence to reduce the overall incidence of cardiovascular disease. A high NaCl diet convincingly contributes to elevated arterial pressure in humans and animal models of hypertension. Among individuals there is considerable variability of blood pressure responsiveness to NaCl intake. In normotensive as well as hypertensive subjects, blood pressure can be judged to be salt sensitivity (SS) when observed to vary directly and substantially with the net intake of NaCl. The prevalence of SS in normotensive adults in the U.S. ranges from 15% to 42% and in hypertensive adults from 28% to 74%. SS is a risk factor for hypertension and may be an important marker in the identification of children for hypertension prevention programs. High NaCl intakes produce expansion of the extracellular fluid volume and thus increase blood pressure. Nonchloride salts of sodium does not expand the extracellular fluid volume and does not alter blood pressure. Blood pressure response to NaCl may be modified by other components of the diet. Low dietary intakes of potassium or calcium augment NaCl-induced increases of blood pressure. Conversely, high dietary intakes of potassium or calcium attenuate NaCl-induced hypertension. A greater intakes of potassium or calcium may prevent or delay the occurrence of hypertension. SS occurs when dietary potassium is even marginally deficient but is dose-dependently suppressed when dietary potassium is increased within its normal range. Orally administered KHCO$_3$, abundant in fruits and vegetates, but not KCl has a calcium-retaining effect which may contributed to its reversal of pressor effect of dietary NaCl. Since nutrients other than NaCl also affect blood pressure levels, a reduced NaCl intake should be only one component of a nutritional strategy to lower blood pressure.

• Journal of Sasang Constitutional Medicine
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• v.31 no.2
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• pp.22-30
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• 2019

Objectives The aim of this study is to investigate the related factors of nonalcoholic fatty liver disease (NAFLD). Methods The subjects were 187 persons diagnosed as fatty liver by abdominal ultrasonography. They were divided into three groups according to the severity of fatty liver: control, mild, moderate or severe. The three groups' general characteristics, laboratory results, liver function indexes, metabolic syndrome indexes, tumor markers, heart rate variability values and Sasang constitution distribution were compared and analyzed. Results Male ratio, height, weight, body mass index, red blood cell count, hemoglobin level and creatinine level were higher in NAFLD groups than in control group. The levels of sodium and amylase were higher in control than in NAFLD. In liver function, the levels of aspartate transaminase, alanine transaminase and gamma-glutamyl transpepsidase of NAFLD were higher. In metabolic syndrome index, systolic blood pressure, diastolic blood pressure, waist circumference, total cholesterol, triglyceride and low density lipoprotein cholesterol levels were higher in NAFLD, while high density lipoprotein cholesterol level was higher in control. The alpha-feto protein level was higher in NAFLD, and the heart rate variability was not different between NAFLD and control groups. In Sasang constitution, Taeeumin ratio of NAFLD was higher than of control. Conclusions The results suggest that nonalcoholic fatty liver is clinically related to liver dysfunction, metabolic syndrome, tumor markers, and Sasang constitution. Further studies are needed to control nonalcoholic fatty liver disease and prevent severe disease such as cirrhosis and cancer caused by fatty liver.

• Journal of Pharmacopuncture
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• v.12 no.1
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• pp.35-42
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• 2009

1. Objectives To evaluate effects of bee venom acupuncture on cardiovascular system and differences according to each constitution. 2. Methods Heart rate variability, pulse wave and the velocity of cerebral blood flow were measured before bee venom acupuncture(BVA), right after and after 30 minuets, had been applied to 20 subjects. 3. Results 1. BVA did not have effects on measurement variables of heart rate variability. 2. BVA had effects on pulse wave, showing total time, radial augmentation index up and height of percussion wave, time to percussion wave, sum of pulse pressure down. 3. BVA did not have effects on the cerebral blood flow velocity when considering not Sasang Constitution. 4. Considering Sasang Constitution, BVA demonstrates different responses in time to preincisura wave, mean blood flow velocity, peak systolic velocity and end diastolic velocity. 4.Conclusion From those results, the following conclusions are obtained. Cause BVA alters pulse wave and makes differences in the cerebral blood flow velocity according to Sasang Constitution. Various methods of BVA treatment are needed considering Sasang Constitution.

• The Korean Journal of Pain
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• v.19 no.2
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• pp.202-206
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• 2006

Background: Stellate ganglion block (SGB) might be associated with changes in the blood pressure (BP) and heart rate (HR). The heart rate variability (HRV) shows the balance state between sympathetic and parasympathetic activities of the heart. The changes in these parameters of the HRV were studied to evaluate the possible mechanism of SGB in changing the BP. Methods: SGB was performed on 26 patients, using a paratracheal technique at the C6 level, and 8 ml of 1% mepivacaine injected. The success was confirmed by check the Horner's syndrome. The BP, HR and HRV were measured before and 5, 15, 30, 45 and 60 minutes after the SGB. Results: The increases in the BP from the baseline throughout the study period were statistically, but not clinically significant. The HR and LF/HF (low frequency/high frequency) ratio were increased at 5 and 45 min, respectively, after the administration of the SGB. In a comparison of left and right SGB, no significant differences were found in the BP, HR and HRV. A correlation analysis showed that an increased BP was significantly related with the changes in the LF/HF ratio and LF at 15 and 30 minutes, respectively, after the SGB. Dividing the patients into two groups; an increased BP greater and less than 20% of that at the baseline INC and NOT groups, respectively, hoarseness occurred more often in the INC group (P = 0.02). Conclusions: It was concluded that SGB itself does not clinically increase the BP and HR in normal hemodynamic patients. However, the loss of balance between the sympathetic and parasympathetic nerve system, attenuation of the baroreceptor reflex and hoarseness are minor causes of the increase in the BP following SGB; therefore, further studies will be required.

• Journal of Biomedical Engineering Research
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• v.28 no.4
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• pp.449-454
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• 2007

An electrohydraulic (EH) pump-driven closed-loop blood pressure regulatory system was developed based on flow-mediated vascular occlusion using the vascular occlusive cuff technique. It is very useful for investigating blood pressure-dependant physiological variability, in particular, that could identify the principal mediators of renal autoregulation, such as tubuloglomerular feedback (TGF) and myogenic (MYO), during blood pressure regulation. To address this issue, renal perfusion pressure (RPP) should be well regulated under various experimental conditions. In this paper, we designed a new EH pump-driven RPP regulatory system capable of implementing precise and rapid RPP regulation. A closed-loop servo-controlwas developed with an optimal proportional plus integral (PI) compensation using the dynamic feedback RPP signal from animals. An in vivo performance was evaluated in terms of flow-mediated RPP occlusion, maintenance, and release responses. Step change to 80 mmHg reference from normal RPP revealed steady state error of ${\pm}3%$ during the RPP regulatory period after PI action. We obtained rapid RPP release time of approximately 300 ms. It is concluded that the proposed EH RPP regulatory system could be utilized in in vivo performance to study various pressure-flow relationships in diverse fields of physiology, and in particular, in renal autoregulation mechanisms.