• The Journal of Korean Medicine
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• v.18 no.1
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• pp.456-469
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• 1997

The cerebral infarction arised from occulsion of cerebral artery has a high mortality rate and fatal sequelae. Sohabhyangwon(蘇合香元) is generally regarded to have a effect of walking up the patient from unconsiousness and promoting the flow of Qj(氣) by warming channel. METHOD The purpose of this study is to find out the effections of Sohabhyangwon(蘇合香元) on regional cerebral blood flow and relative cerebral infarction area in the experimentally induced infartion in rats In this experiment, 12 Spraque-Dawley rats weighting 280-350g were used. Cerebral ischemia induced by intraluminal suture technique of Kozumi's and Zea-Longer's method. $Co_{2},\;O_2$, pH, arterial blood pressure in rats were checked by Blood Gas Analyzer every 30 minutes for 2 hours. And regional cerebral blood flow were checking by hydrogen clearance technique, cerebral infarcted area was megsured by Image Analysis System. RESULTS 1. During the experiment, $CO_{2},\;O_2$, pH, arterial blood pressure in rats had no change in both sample group and control group. 2. Cortical cerebral blood flow decreased at same rate in both sample group and control group after inducing cerebral infarction. 3. On comparison of relative cerebral infarcted area, Sohabhyangwon(蘇合香元) perfused group showed a significant decrease. CONCLUSION According to the result above, Sohabhyangwon has a protection effect on cranial nerve and-has no effect on cerebral blood flow.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.24 no.11
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• pp.1411-1416
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• 2020

In this paper, we propose a method of extraction analysis of blood flow area on color doppler ultrasonography by using 4-directional contour tracking and K-Means algorithm. In the proposed method, ROI is extracted and a binarization method with maximum contrast as a threshold is applied to the extracted ROI. 4-directional contour algorithm is applied to extract the trapezoid shaped region which has blood flow area of brachial artery from the binarized ROI. K-Means based quantization is then applied to accurately extract the blood flow area of brachial artery from the trapezoid shaped region. In experiment, the proposed method successfully extracts the target area in 28 out of 30 cases (93.3%) with field expert's verification. And comparison analysis of proposed K-Means based blood flow area extraction on 30 color doppler ultrasonography and brachial artery blood flow ultrasonography provided by a specialist yielded a result of 94.27% accuracy on average.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.4
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• pp.481-486
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• 2013

To investigate the effects of facial temperature and blood flow rates generated by Miso Facial Rejuvenation Acupuncture treatment. Ten women in their twenties to fifties with no skin diseases were recruited. Miso Facial Rejuvenation Acupuncture(MFRA) was performed on the both sides of their face. We measured their facial temperature using Digital Infrared Thermal Imaging(DITI) and blood flow rates using Laser Doppler Perfusion Imaging(LDPI) at pre-treatment, immediately, twenty and sixty minutes after treatment. We analyzed data using student's t-test(p<0.05). After MFRA treatment, facial temperature on the measurement area increased immediately from $30.5{\pm}1.0^{\circ}C$ to $31.5{\pm}1.0^{\circ}C$, a statistically significant increase. Sixty minutes after treatment, facial temperature on the measurement area decreased a little bit($30.2{\pm}0.6^{\circ}C$), but there was no statistical significance. After MFRA treatment, facial blood flow rates on the measurement area increased immediately from $165.1{\pm}52.3$ PU to $342.7{\pm}51.3$ PU, a statistically significant increase. Sixty minutes after treatment, facial blood flow rates measurement area were recovered almost at the same level as before treatment. MFRA treatment could increase facial temperature and blood flow rates.

• The Korean Journal of Nuclear Medicine
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• v.1 no.2
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• pp.1-25
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• 1967

In 20 normal cases and 39 pulmonary tuberculosis cases, regional pulmonary arterial blood flow measurements and lung perfusion scans by $^{131}I$-Macroaggregated albumin, lung inhalation scans by colloidal $^{198}Au$ and spirometries by respirometer were done at the Radiological Research Institute. The measured lung function tests were compared and the results were as the following: 1. The normal distribution of pulmonary blood flow was found to be $54.5{\pm}2.82%$ to the right lung and $45.5{\pm}2.39%$ to the left lung. The difference between the right and left pulmonary arterial blood flow was significant statistically (p<0.01). In the minimal pulmonary tuberculosis, the average distribution of pulmonary arterial blood flow was found to be $52.5{\pm}5.3%$ to the right lung and $47.5{\pm}1.0%$ to the left lung when the tuberculous lesion was in the right lung, and $56.2{\pm}4.4%$ to the right lung and $43.8{\pm}3.1%$ to the left lung when the tuberculous lesion was in the left lung. The difference of pulmonary arterial blood flow between the right and left lung was statistically not significant compared with the normal distribution. In the moderately advanced pulmonary tuberculosis, the average distripution of pulmonary arterial blood flow was found to be $26.9{\pm}13.9%$ to the right lung and $73.1{\pm}13.9%$ to the left lung when the tuberculous lesion was more severe in the right lung, and $79.6{\pm}12.8%$ to the right lung and $20.4{\pm}13.0%$ to the left lung when the tuberculous lesion was more severe in the left lung. These were found to be highly significant statistically compared with the normal distribution of pulmonary arterial blood flow (p<0.01). When both lungs were evenly involved, the average distribution of pulmonary arterial blood flow was found to be $49.5{\pm}8.01%$ to the right lung and $50.5{\pm}8.01%$ to the left lung. In the far advanced pulmonary tuberculosis, the average distribution of pulmonary arterial blood flow was found to be $18.5{\pm}11.6%$ to the right lung and $81.5{\pm}9.9%$ to the left lung when the tuberculous lesion was more severe in the right lung, and $78.2{\pm}8.9%$ to the right lung and $21.8{\pm}10.5%$ to the left lung when the tuberculous lesion was more severe in the left lung. These were found to be highly significant statistically compared with the normal distribution of pulmonary arterial blood flow (p<0.01). When both lungs were evenly involved the average distribution of pulmonary arterial blood flow was found to be $56.0{\pm}3.6%$ to the right lung and $44.0{\pm}3.2%$ to the left lung. 2. Lung perfusion scan by $^{131}I$-MAA in patients with pulmonary tuberculosis was as follows: a) In the pretreated minimal pulmonary tuberculosis, the decreased area of pulmonary arterial blood flow was corresponding to the chest roentgenogram, but the decrease of pulmonary arterial blood flow was more extensive than had been expected from the chest roentgenogram in the apparently healed minimal pulmonary tuberculosis. b) In the pretreated moderately advanced pulmonary tuberculosis, the decrease of pulmonary arterial blood flow to the diseased area was corresponding to the chest roentgenogram, but the decrease of pulmonary arterial blood flow was more extensive in the treated moderately advanced pulmonary tuberculosis as in the treated minimal pulmonary tuberculosis. c) Pulmonary arterial blood flow in the patients with far advanced pulmonary tuberculosis both before and after chemotherapy were almost similar to the chest roentgenogram. Especially the decrease of pulmonary arterial blood flow to the cavity was usually greater than had been expected from the chest roentgenogram. 3. Lung inhalation scan by colloidal $^{198}Au$ in patients with pulmonary tuberculosis was as follows: a) In the minimal pulmonary tuberculosis, lung inhalation scan showed almost similar decrease of radioactivity corresponding to the chest roentgenogram. b) In the moderately advanced pulmonary tuberculosis the decrease of radioactivity in the diseased area was partly corresponding to the chest roentgenogram in one hand and on the other hand the radioactivity was found to be normally distributed in stead of tuberculous lesion in the chest roentgenogram. c) In the far advanced pulmonary tuberculosis, lung inhalation scan showed almost similar decrease of radioactivity corresponding to the chest roentgenogram as in the minimal pulmonary tuberculosis. 4. From all these results, it was found that the characteristic finding in pulmonary tuberculosis was a decrease in pulmonary arterial blood flow to the diseased area and in general decrease of pulmonary arterial blood flow to the diseased area was more extensive than had been expected from the chest roentgenogram, especially in the treated group. Lung inhalation scan showed almost similar distribution of radioactivity corresponding to the chest roentgenogram in minimal and far advanced pulmonary tuberculosis, but there was a variability in the moderately advanced pulmonary tuberculosis. The measured values obtained from spirometry were parallel to the tuberculous lesion in chest roentgenogram.

• The Journal of Korean Physical Therapy
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• v.28 no.2
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• pp.136-141
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• 2016

Purpose: In this study experiments were performed during 6 weeks with 40 adults, 20 subjects in the waist stabilization exercise with blood flow restriction group and 20 subjects in the waist stabilization exercise without blood flow restriction group, in order to determine the impact of waist stabilization exercise on White Area Index (WAI) followed by blood flow restriction. Methods: Thickness of external oblique abdominal muscle, internal oblique abdominal muscle, and transversus abdominis muscle, as well as density and WAI of external oblique abdominal muscle were measured, followed by performance of repeated ANOVA. Results: Significant difference in thickness of external oblique abdominal muscle according to periodical difference was observed between groups (p<0.05). Significant difference in thickness of internal oblique abdominal muscle and transversus abdominis muscle according to periodical difference was observed between groups (p<0.05). Significant difference in density and WAI of external oblique abdominal muscle according to periodical difference was observed between groups (p<0.05). Conclusion: In conclusion, significant difference was observed after waist stabilization exercise with blood flow restriction. These results can be used as basic data for future research on waist stabilization exercise and blood flow restriction exercise.

• Journal of information and communication convergence engineering
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• v.16 no.4
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• pp.258-263
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• 2018

Color Doppler sonography is a useful tool for examining blood flow and related indices. However, it should be done by well-trained operator, that is, operator subjectivity exists. In this paper, we propose an automatic blood flow area extraction method from brachial artery that would be an essential building block of computer aided color Doppler analyzer. Specifically, our concern is to examine hypertension suspicious (prehypertension) patients who might develop their symptoms to established hypertension in the future. The proposed method uses fuzzy C-means clustering as quantization engine with careful seeding of the number of clusters from histogram analysis. The experiment verifies that the proposed method is feasible in that the successful extraction rates are 96% (successful in 48 out of 50 test cases) and demonstrated better performance than K-means based method in specificity and sensitivity analysis but the proposed method should be further refined as the retrospective analysis pointed out.

• Journal of the Korean Magnetics Society
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• v.26 no.4
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• pp.142-148
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• 2016

To evaluate the effect of flip angle on flow rate measurements obtained with phase contrast MRI according to the flip angle degree in ascending aorta and velocity encoding (VENC) was (150 m/s). 1.5T MRI in patients 17 (female: 8, male: 9, mean age $57.9{\pm}15.4$) as a target by applying a non-breath holding techniques to flip angle VENC (150 cm/s) in each of the ascending aorta was measured by changing $20^{\circ}$, $30^{\circ}$ and $40^{\circ}$. Blood was obtained a peak velocity, average velocity, net forward volume, net forward volume/body surface area. Ascending aorta from average velocity (AV) measured the average value of the flip angle $20^{\circ}$ (9.87 cm/s), $30^{\circ}$ (9.6 cm/s) and $40^{\circ}$ (10.05 cm/s). Blood flow VENC in was blood flow change in flip angle change was high most blood flow measurement when the flip angle $30^{\circ}$ in VENC, crouching each blood flow is also proportional to the increases in the $20^{\circ}$ to $40^{\circ}$ and was increased, the deviation of the peak velocity and the average velocity is the smallest deviation from the flip angle $30^{\circ}$. Flip angle $20^{\circ}$, $30^{\circ}$ and $40^{\circ}$ in peak velocity, average velocity, net forward volume, net forward volume/body surface area was no statistically significant difference (p > .05). Blood flow velocity and blood flow is measured by applying to adjust the flip angle accurately calculate the blood flow is important information for diagnosis and treatment of cardiovascular diseases, and can help in the examination on the blood flow measurement.

• Journal of Chest Surgery
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• v.25 no.5
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• pp.451-457
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• 1992

The hollow fiber oxygenator is the most advanced one for the cardiopulmoanry bypass. They have two different types of the hollow fiber systems according to the way how the blood go through the fibers. One is inside blood flow type and the other outside type. In order to find out which is better to prevent blood cell destruction, we selected 40 valve replacing patients and divided them into 2 groups prospectively. In group I [n=20], inside blood flow type[BCM-7a], CO2 excretion is more effective than group II, that is partly because of the relative large surface area of the BCM-7. In group II [n=20], outside blood flow type [MAXIMAa], they have better quality to preserve platelet count. We also studied about several other items such as SaO2, Hemoglobin and RBC, WBC, fibrinogen, LDH, plasma hemoglobin, haptoglobulin and so on. But we cannot find any differences between two groups with any statistical meanings [p<0.05]. We conclude that both of two oxygenators are excellent in the aspects of gas exchange and blood cell preservation.

• Journal of Information Processing Systems
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• v.15 no.4
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• pp.820-832
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• 2019

Estimation of accurate blood volume flow in ultrasound Doppler blood flow spectrograms is extremely important for clinical diagnostic purposes. Blood volume flow measurements require the assessment of both the velocity distribution and the cross-sectional area of the vessel. Unfortunately, the existing volume flow estimation algorithms by ultrasound lack the velocity space distribution information in cross-sections of a vessel and have the problems of low accuracy and poor stability. In this paper, a new robust ultrasound volume flow estimation method based on multigate (RMG) is proposed and the multigate technology provides detail information on the local velocity distribution. In this method, an accurate double iterative flow velocity estimation algorithm (DIV) is used to estimate the mean velocity and it has been tested on in vivo data from carotid. The results from experiments indicate a mean standard deviation of less than 6% in flow velocities when estimated for a range of SNR levels. The RMG method is validated in a custom-designed experimental setup, Doppler phantom and imitation blood flow control system. In vitro experimental results show that the mean error of the RMG algorithm is 4.81%. Low errors in blood volume flow estimation make the prospect of using the RMG algorithm for real-time blood volume flow estimation possible.

• Journal of International Academy of Physical Therapy Research
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• v.1 no.2
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• pp.99-106
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• 2010

The purpose of this study was to identify the effects of manipulation on the velocity of cerebral blood flow and level of pain in cervicogeinc headache patients. The velocity of cerebral blood flow of 30 cervicogeinc headache patients(male=15, female=15, age=$24.00{\pm}3.60$) and 33 normal subjects(male=15, female=18, age=$23.27{\pm}3.00$) was compared. The 30 cervicogeinc headache patients were divided into suboccipitalis relaxation group, cervical manipulation group, and placebo group, and each were given different interventions. The velocity of cerebral blood flow and pain level was measured before intervention, and 1, 2, 3 weeks after intervention. The velocity of cerebral blood flow was measured with the Transcranial Doppler(TCD), and pain level was measured with visual analog scale(VAS). Blood flow velocity of middle cerebral artery in cervicogeinc headache patients was slower than those in healthy subjects. Physical therapy intervention did not have significant effect on velocity of cerebral blood flow, but slowly decreased at intervention for pain level increased. The suboccipitalis relaxation group and cervical manipulation group showed significant effect in decreasing pain level compared to the placebo group(p<.05). Directly applied manipulation therapy in the neck area not only has effect on joint of cervical and soft tissue but also on blood vessels and nerves which pass the neck area, and because of those results of manual therapy seems to help recovery.