• 동의신경정신과학회지
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• 제9권2호
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• pp.53-69
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• 1998

This experiment was done to investigate the effects of GAMIKWYBICHONGTANG(GKCT) on the blood and brain tissues of aged rats. The experimental groups were divided into three groups and treated as follows for ten days before administration of scopolamine ; Non treated group(Normal), Distilled water feeding group (Control), GKCT feeding group(GKCT). After feeding them each, Control and GKCT were injected scopolamine for 5 days.We examined the changes of blood cell(WBC, RBC, platelet), blood serum(BUN, creatinine, glucose, uricacid), erythrocyte hemolysis, the activities of cholinesterase, and measured the amounts of malondialdehyde of the blood serum and checked the activities of catalase, SOD of the brain tissues.The results were as follows;1. GKCT showed significant increase of the number of WBC, but those of RBC and platelet didn't significantly changed in comparison with Control.2. GKCT showed significant decrease of BUN, creatinin, glucose, uric acid in blood serum in comparison with Control.3. Erythrocyte hemolysis were decreased significantly in GKCT in comparison with Control.4. About the activity of cholinesterase of blood serum, GKCT showed no significant increase in comparison with Control.5. In TBA reaction to measure the amount of MDA, oxidant material of blood serum of rats, GKCT showed significant decrease in comparison with Control.6. About the activity of catalase of brain tissue, GKCT showed no significant change in comparison with Control.7. About the activity of SOD of brain tissue, GKCT showed significant increse in comparison with Control.According to the above results, GKCT can reduce the formation of free radical and the accumulation of antioxidant materials, it is suggested that GAMIKWYBICHONGTANG(GKCT) has some effects on antiaging. It is also needed more following studies.

• 대한예방한의학회지
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• 제4권1호
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• pp.17-31
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• 2000

In order to investigate the effects of emitted-qi therapy(EQT) and cold water therapy(CWT) on the inhibition of the blood loss, the protein loss and the electrolyte loss in burned rats. The white blood cell, hematocrit and hemoglobin values in blood, and the total protein, albumin, globulin, $Na^+,\;Cl^-,\;K^+\;and\;Ca^{2+}$ values in serum were measured. The results were obtained as follows; 1. White blood cell count in blood was significantly increased in CWT group compared with control group. 2. Hematocrit value in bolld was significantly increase in EQT and CWT group compared with control group. 3. Hemoglobin value in blood was significantly increased in CWT group compared with control group. 4. Total protein value in serum was significantly increased in CWT group compared with control group. 5. Albumin value in serum was significantly increased in EQT and CWT group compared with control group. 6. Globulin value in serum tended to be increase in EQT and CWT group compared with control group, but it was not significant. 7. A/G ratio in serum was significantly increased in EQT and CWT group compared with contort group. 8. $Na^+$, value in serum was significantly increased in EQT and CWT group compared with ontrol group. 9. $K^+$, value in serum tended to be increased in EQT group compared with control group, but it was not significant. 10. $Cl^-$ value in serum was significantly increased in EQT and CWT group compared with control group. 11. $Ca^{2+}$ value in serum tended to be increased in EQT and CWT compared with control group, but it was not significant. According to the above results, the EQT and CWT inhibited the blood loss, the protein loss and the electrolyte loss. Therefore, it is considered that the EQT and CWT can be applied to the burn therapy.

• 동의생리병리학회지
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• 제24권4호
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• pp.553-558
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• 2010

Nutrient and Blood are really common conceptions in Traditional Korean Medicine(TKM). However, those are used in mixed. not only because of their common points but users who doesn't have clear classifications between them. Therefore, I will explain those owns by explaining origins, places of origons, pathway, circulations, organs related to them and color. In addition, I will try to explain thi things in common without conceptions of their own. As a result, the first, nutrient is what is originated from water and food at middle energizer and circulated in meridian vessel by control of spleen. The second, blood is what is originated from qi of water and food and circulated in blood vessel by control of heart and its color is red. The third, nutrient blood is what is originated from water and food or qi of water and food and circulated in meridian or blood vessel by control of spleen and heart. Also it is red and its function is nourishing human body. The name of Nutrient blood is a new term that I made and it is different from nutrient or blood. Also it is different from nutrient and blood. Nutrient blood is combination by conceptions, nutrient and blood is combination by word itself.

• 센서학회지
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• 제16권1호
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• pp.44-51
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• 2007

A hybridized simulator for generating blood pressure waveform is proposed to study the remedy and/or evaluation of the conventional sphygmomanometer utilizing the oscillometric method which is widely applied. The blood pressure of a flowing fluid was controlled for the blood vessel's condition caused by a rhythmical and periodical contraction/relaxation because of the special excitatory and conductive system of the heart. In this study, a hybridized controller composed of the PI feedback controller and the feedforward controller. The inverse dynamics function is proposed to operating the control valve while the pressure is applied in an oil pressure tank. The proposed hybrid simulator reproducing the blood pressure waveform in an artificial blood vessel has kept the control performance consistent over all range. Based on these results, the proposed simulators could be applied to the development and compensation of the non invasive sphygmomanometer type as well as to study the characteristics of the blood pressure and blood vessel.

• 대한한의학회지
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• 제16권1호통권29호
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• pp.351-369
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• 1995

In order to investigate the effect of Qingbaozhuyutang(淸胞逐瘀湯), Bee Veenom on 'Blood Stasis Pattern', here We regard Thrombosis and Elevated Blood viscosity as Blood Stasis Pattern. rats were injected Endotoxin into the caudal vein to make experimental thrombosis model(control group), and at sample group, rats were orally administrated solid extract of Qingbaozhuyutang(淸胞逐瘀湯) 0.5g/200g or were injected Apitoxin 1mg/Kg into the abdominal region(sample group), and then we observed platelet, fibrinogen, prothrombin time and FDP level. Another group were injected HA into the muscular rump to make experimental elevated blood viscosity instead of Endotoxin. Thereafter we measured whole blood viscosity and plasma viscosity. The results were summarized as follows. 1. Platelets were increased significantly in sample I compared with the control group. 2. Fibrinogen levels were increased significantly in sample I compared with the control group. 3. Prothrombin times were shortened significantly in sample II and sample III compared with the control group. 4. FDP levels were decreased significantly in sample II and sample III compared with the control group. 5. Whole blood viscosity and plasma viscosity were decreased significantly in all shear rates compared with the control group. According to the above results, it is considered that Qingbaozhuyutang(淸胞逐瘀湯) has significant effects on platelets, fibrinogens, prothrombin times, FDP levels, whole blood viscosity and plasma viscosities, therefore it seems to be applicable to disease related to 'Blood Stasis Pattern' through the thrombosis and elevated blood viscosity. But, Veenom has a little effect. the mechanism concerned for the effects is to be investigated in future.

• 대한간호학회지
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• 제39권2호
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• pp.298-309
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• 2009

Purpose: To develop a web-based program on blood-borne infection control and to examine the effect of the newly developed program on perceived threat of diseases, knowledge, preventive health behaviors for blood-borne infections, and incidence rates of accidental needle sticks and other sharp object injuries in nurses. Methods: The program was developed through the processes of analysis, design, development, implementation, and evaluation. The research design involved a nonequivalent control group for pretest and posttest experiments. The setting was a 745-bed general hospital located in Korea. Results: The program was designed and developed after consulting previous studies. After development of the program was completed, it was evaluated and revised by a panel of experts. The total score for perceived threat of diseases, knowledge, preventive health behaviors in the experimental group was significantly higher compared to the control group (p<.05). The incidence rates for needle sticks and other sharp object injuries in the experimental group were significantly lower compared to the control group (p<.05). Conclusion: Application of a Web-based, blood-borne infection control program is effective, and can be expanded to other healthcare workers who also have a high risk of blood-borne infections.

• 대한한방내과학회지
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• 제26권1호
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• pp.12-47
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• 2005

First, mice were dosed with 50mg/kg of streptozotocin(STZ) twice every 24 hours to cause high blood-sugar. Then, after three days, mice were injected with 100mg/kg of STZ again. Two different dosages of Saengjihwangeumja-gami were given to the experiment groups: SA group, 15mg/kg/day, and SB group, 90mg/kg/day, in order to determine the effects of Saengjihwangeumja-gami, which has been known to be good for DM(Diabetes Mellitus). By observing weight and blood-sugar level changes, blood tolerance, the numerical value of BUN(Blood Urea Nitrogen) and creatinine in blood, and through light-electronicmicroscopic and immunohistologic investigations of pancreas and kidneys, the following results were obtained: 1. The experiment groups showed a high suppressive effect of weight-loss. 2. The experiment groups' blood-sugar and blood tolerance showed an effective lowering of blood-sugar levels. 3. The experiment groups did not show any noticeable change in the numerical value of BUN and creatinine in blood compared with that of the control groups. 4. The experiment groups showed a higher Insulin positive reaction of pancreatic islets ${/beta}-cell$ than the control groups. 5. The experiment groups showed a higher immuno-reaction against IGF- II than the control groups. 6. Observation of apoptosis of the pancreatic islets showed that the cells of experiment groups were less injured compared with those of the control groups, and fewer apoptag-positive reaction cells were seen in experiment groups than in the control groups. 7. Uunder electron-microscopy, the insulin-containing granules in pancreatic islets ${/beta}-cells$ had increased more in the experiment groups than in the control groups. 8. Under light microscopy, the injury on the inner & outer membrane of the glomerulus and epithelial cells of capillaries and cells among vessels were fewer in the experiment groups than in the control groups. 9. More apoptag-positive reaction cells in the kidney were seen in the control groups than in the experiment groups. 10. PAS-positive reaction substances had increased more in the substrate among the vessels of a glomerulus belonging to the control group than those of the experiment group. 11. Uunder electron-microscopy, the nucleonic membrane, nucleoplasm and mitochondria of proximal and distal renal tubular were more injured in the control groups than in the experiment groups. In conclusion, strong evidence for the efficacy of Saengjihwangeumja-gami in lowering blood-sugar, and in recovery and generation of pancreatic tissues injured by DM was observed. Results suggest Saengjihwangeumja-gami is an effective treatment for DM. Further study of the principles of blood-sugar dropping effects of Saengjihwangeumja-gami are needed, as well as further study of recovery and regeneration of pancreatic tissues injured by DM.

• 지역사회간호학회지
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• 제17권4호
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• pp.461-471
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• 2006

Purpose: The Purpose of this study was to evaluate the effects of antioxidant vitamins and minerals supplementation on blood pressure and lipids in the elderly with hypertension. Methods: This study adopted a unequivalent control group pretest-posttest design. For this study, 79 subjects with hypertension were selected among the home visiting clients of public health centers. The experimental group received 12-weeks' treatment with antioxidant vitamin A, C, E, carotene, magnesium and selenium and the control group did not take any antioxidant vitamin and mineral. Results: There were statistical differences in systolic blood pressure and diastolic blood pressure between the experimental group and the control group after the intervention. In the experimental group, systolic blood pressure decreased from 145.4mmHg before the intervention to 135.7mmHg after the intervention, and diastolic blood pressure decreased from 88.3mmHg before the intervention to 81.9mmHg after the intervention. However, there were no statistical differences in total cholesterol and triglyceride between the experimental group and the control group after the intervention. Conclusions: A short-term supplementation with antioxidant vitamins & minerals can reduce blood pressure in the elderly with hypertension. The continuous effects of the supplementation and its beneficial effects on the prevention of cardiovascular diseases still need to be studied further.

• 한국식품영양과학회지
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• 제7권2호
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• pp.29-34
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• 1978

It was conducted to find out that the influence of lipids on blood cholesterol level of chicks and ducks. In this experiments, a comparative study was carried out using chicks and ducks divided into four groups with various diet for the period of four weeks. The results were as follows: 1. The mean value of hematocrit was significantly lower for the chicks fed sesame oil and soybean oil than the chicks fed duck meat. The value of hematocrit was higher for the ducks fed sesame oil, soybean oil and duck meat than for the control group. 2. Blood glucose level was higher for the ducks group than the chicks group. It was lower blood glucose level for the chicks and ducks fed duck meat than any other groups. 3. Blood cholesterol level was lower for the chicks fed sesame oil, soybean oil, and duck meat than for those fed the basal diet(control group). In the ducks group, blood cholesterol level was high. But in the liver organ, it was lower blood cholesterol level for the chicks and ducks fed sesame oil, soybean oil and duck meat, respectively than for those fed the basal diet(control group). 4. Phospholipid of the chicks which were control groups was lower value than for those fed sesame oil and duck meat fed, the value of phospholipid was higher value.

• 임상간호연구
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• 제15권3호
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• pp.27-38
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• 2009

Purpose: The purpose of this study was to develop a blood glucose control protocol for medical intensive care unit (ICU) patients. Methods: The blood glucose control protocol was developed through the following process: selection of preliminary protocols, clinical application, and evaluation. The clinical validity of the protocol was measured by application, along with examination of the effects of the Yale and the Mayo blood glucose protocols. Seventeen medical ICU adults patients whose blood glucose levels exceeded 200 mg/dL consecutively participated in the study. The development protocol was evaluated by an expert group. Results: Incidence of normal blood glucose levels (p=.041) increased significantly in the Yale protocol application group. Also, incidence of severe hyperglycemia (p=.029) decreased significantly and time to target range of glucose (p=.023) decreased significantly after application of the Yale protocol. However, there was no significant difference in incidence of hypoglycemia (p=.666) between three groups. Conclusion: Using the developed protocol as a basis for the modified Yale protocol was found to be effective in improving the state of blood glucose control for medical ICU patients and is expected to be used for nursing intervention in critical care.