• 한국어병학회지
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• 제2권2호
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• pp.91-98
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• 1989

미야이리균(Clostridium butyricum Miyairi II 588)을 담수산 양식어류인 잉어, 틸라피아, 이스라엘잉어에 첨가하여 사육한 결과 다음과 같은 결과를 얻었다. 1. 잉어, 틸라피아, 이스라엘잉어에 대한 사육 실험 결과 0.1%의 미야이리균을 첨가한구에서 가장 효율적인 성장율을 나타내었다. 2. 각 어종의 혈액 검사를 실시하여 본 결과 혈액내의 적혈구수, 헤모글로빈량, 헤마토크릿트치에서는 이상을 발견할 수 없었으며, 혈청내 단백질의 증가와, 콜레스테롤의 감소, 글루코스의 증가가 나타났다. 3. 혈청내의 GOT와 GPT는 정상어제의 수치와 유사하게 나타났다.

• Asian-Australasian Journal of Animal Sciences
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• 제3권4호
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• pp.293-298
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• 1990

Pathogen infections or mastitis inflammations usually develop differently on each udder of lactating cow. Although healthy udders will be attacked by the mastitis pathogens or the pathogens from blood in a long term, they would not be always inflamed. Somatic cell counts (SCC) in milk, which is utilized as an index of mastitis diagnosis, and the relation among SCC and milk constituents will have to be examined on each udder individually. Twelve cows of a Holstein cow herd in Nasu Research Station, which were suffering clinical or non-clinical mastitis, were selected, and SCC and milk constituents on each udder milk were measured. The effects of mastitis infection on udder milk components were relatively small except lactose content on udder milks of non-clinical mastitis (SCC< $10.0{\times}10^5$ per ml milk). On udder milks of clinical mastitis, however, high negative correlations were recognized between SCC and milk components. On different sampling days, high contents of fat and protein corresponded to that of total solids.

• Journal of Nutrition and Health
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• 제31권9호
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• pp.1481-1497
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• 1998

The purpose of this study was to determine the relation between serum lipid profiles, apolipoprotein E phenotype, and dietary patterns in a cross-section of healthy individuals from Cheju-Do. Age, gender, anthropometric measurements, blood pressure, dietary consumption, drinking / smoking habits and menopausal status were surveyed. Total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, fasting blood glucose, and insulin levels were measured from overnight fasting blood. The study involved a total of 286 individuals(147 men and 139 women) between the ages of 20 and 60 years old. All of the subjects were recruited from a population of healthy individuals living in Cheju-Do. The results of the study are as follows : 1) Among the males, those in their 20's had the maximum food intake, while those in their 40's had the minimum food intake. For the females, food intake was the highest for those in their 30's. Energy and nutrient intakes were directly proportional to the amount of food intake. Men in their 30's were heavier than other men and women in their 40's were heavier than other women. The activity index for men in their 20's and 30's appeared to be lower than that of men above 40. The activity index of women in their 20's appeared to be lowest among all aged groups, and the index appeared to increase from the age of 30 onwards. 2) In terms of changes In serum constituents with age, men in their 40's appeared to have the highest levels of serum constituents such as lipids, glucose, and insulin. Men in their 50's showed the highest levels of serum LDL-cholesterol and glucose. Men in their 30's showed peak levels of serum triglycerides. On the other hand, women in their 50's appeared to have peak levels of serum total cholesterol, LDL-cholesterol, and triglycerides. There was no ch:ange with age in HDL-cholesterol and insulin levels for men and women. The percentage of the subjects had the following apo E phenotypes : E3/3, 91.3% ; E3/2, 5.4% ; E4/3, 2.5% ; E4/2, 0.7%. Lee's reserch with Korean female college students showed that the percentage of ApoE3/3, E3/2, E 4/2, E4/3, and E4/4 were 84.8%, 6.7%, 6.7%, 0.9%, 0.9%, respectively. The number of samples with ApoE mutation was so small that there was no statistical significance in the relation between apolipoprotein E phenotype and se겨m lipids. 3) To investigate the relati onship between weight and serum constituents, the subjects of this study were divided into three groups by BMI underweight, normal weight, and overweight. The serum constituents of men and women below the age 40 in the overweight groups belonged to the normal domain. On the other hand, serum cholesterol levels of both men and women above the age 40 in the overweight groups remained in the borderline-high region(above 200mg/dl), and the mean value of LDL-cholesterol(above 130mg/dl) and triglycerides of men were above normal. Fasting blood glucose levels also remained in the borderline-high region. Total cholesterol levels of women above the age 40 in the overweight group was in the borderline-high region. (Korean J Nutrition 31(9) : 1481-1497, 1998)

• The Korean Journal of Physiology
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• 제20권2호
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• pp.279-288
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• 1986

줄넘기 운동의 신체 단련 효과를 측정하기 위하여 사병 9명에게 9주동안 규칙적으로 줄넘기 운동을 시킨 후 체격, 심폐기능, 혈액화학적인 변화를 관찰, 단련전과 비교하여 다음과 같은 결과를 얻었다. 효과를 검사하기 위해 부하한 운동은 트레드밀 달리기 운동이었다. 1) 단련에 의해 몸무게, 체표넓이, 피부두겹두께 및 총지방량이 유의하게 감소하였다. 2) 안정시 폐기능검사 값 중 최대환기능과 노력성 호기유속 25%가 단련후에 유의하게 증가하였다. 3) 심장박동수는 단련에 의해 안정시와 운동시, 회복기 전 시간대를 통해 매우 유의하게 증가하였다. 4) 단련으로 수축기 동맥혈압은 안정시와 회복기 전 시간대에서 거의 유의하게 감소한 반면, 이완기 동맥혈압은 회복기 전체를 통해 유의하게 증가하였다. 5) 안정시와회복기의 호흡회수는 단련에 의해 변화가 없었다. 6) 안정시와 회복 초기의 혈중 총 콜레스테롤 농도는 단련 후에 유의하게 감소하였지만 혈당, HDL-콜레스테롤 농도는 약간의감소에 그쳤다. 7) 단련전에 비해 단련후의 혈중 젖산 농도는 회복기에 대체로 감소하엿고 20분과 60분 값의 감소는 뚜렷하였다. 이상의 결과로 보아 9주 동안의 규칙적인 줄넘기 운동으로 체내 지방이 감소하고 순환기계 기능에 뚜렷한 향상을 가져오며 혈액화학적인 변화가 생긴다고 할 수 있겠다.

• 농업과학연구
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• 제46권3호
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• pp.637-643
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• 2019

The aim of the present study was to evaluate the effect of the induced heat stress on physiological response and serum biochemical parameters involving glucose, cholesterol, blood urea nitrogen (BUN), non-esterified fatty acids (NEFA), and cortisol in Holstein calves. Ten calves were kept in a climate controlled room (air temperature $37^{\circ}C$ and 90% humidity from 09:00 to 19:00) for three days. Those animals were given a one-day adaptation period. During the treatment period, we measured the skin temperature six times. Following the treatment periods, blood samples were collected before the experiment began (09:00) and at the end of the stress period (19:00). To aid analysis of the biochemical parameters, also we monitored the rectal temperature. The results, exhibited that both rectal and skin temperature showed increase in the heat stress-induced animals as compared with unstressed animals. Moreover, we noticed that the levels of BUN and NEFA increased in the blood serum of heat stress induced animals when compared with un-stressed ones. From these results, we concluded that the physiological and biochemical changes in the calves were induced by heat stress. Hence, the present study findings could be employed as base line data for development of stress reduction techniques in the dairy industry.

• Asian-Australasian Journal of Animal Sciences
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• 제11권4호
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• pp.368-374
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• 1998

The study was conducted on six multiparous Murrah buffaloes which were earlier artificially induced into lactation. During the experimental period of 15 days, buffaloes were managed in a loose housing system. All the buffaloes were administered a single injection of bromocryptine (@ $100{\mu}g/kg$ body weight) subcutaneously in the neck region at 08:30 A.M., 50 days postpartum (early lactation). Blood samples were collected from four buffaloes for a period of 5 days before the administration of bromocryptine i.e. on days -5, -4, -3, -2, -1, on day of treatment (day 0) and thereafter daily for a period of 9 days i.e 1, 2, 3, 4, 5, 6, 7, 8 and 9 to determine the hormones and blood metabolites. Homogeneous milk samples from all the buffaloes were collected at morning and evening milkings on days coinciding with the days of blood sampling for analysis of milk constituents. Administration of bromocryptine resulted in a significant inhibition of plasma prolactin within 24 hrs of treatment, but the response in all the buffaloes was not uniform. The effect of bromocryptine on plasma prolactin hormone lasted for 1-4 days but Cortisol concentration were not altered. Administration of bromocryptine neither affected blood glucose nor plasma non-esterified fatty acids concentration. Irrespective of level of milk production from different buffaloes, there was no effect of bromocryptine on milk yield which indicated that prolactin is not required for milk secretion during early lactation in buffaloes. Milk constituents like fat, protein and lactose were not affected by bromocryptine may be due to no effect of bromocryptine of milk yield.

• Journal of Nutrition and Health
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• 제19권6호
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• pp.382-391
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• 1986

This survey was carried out to study the relationship between observable factor such as anthropometry, blood pressure, food habit, the score of THI and diseases of 459 persons (male: 188, female: 271) aged 60 and over in the rural area of Kurye - Gun Chonnam from April 28 to May 1, 1986. The results obtained were as follo\ulcornerws 1) Body weight and height was below Korean average. The mean obesity rate in male and female showed -2.3% and 3.4%, respectively, and BMI showed 25.8 and 26.0 respectively. 2) The systolic and diastolic blood pressure was normal in both sexes. The pro opotion of hypertension by WHO level showed 19.6% and 20.3% in male and fem\ulcornerale, respectively_ The proportion of anemia showed 57.9% and 41.7% in male and female, respectively. The concentration of total protein, albumin, cholesterol and gl\ulcornerucose and white blood cell number showed normal range in both sexes. 3) The proportion of the disease showed 68% of male and 83% of female and among them 50% of male and 43% of female suffered from one kind of disease and there are more female who suffered from many kinds of diseases than male. The most common disease is neuralgia and nexts are digestive diseases, diabetes melli\ulcornertus, urinary disturbance, motion disturbance, arthritis, respiratory diseases, tubecu\ulcornerlosis and hepatitis. 4) There was a significant correlation between body height and weight and the score of food habit. 5) There was a considerable relation between the score of each item of TIll and the status of diseases. 6) There appeared profound relation between obesity rate and the data of anth\ulcornerropometry, but weak relation between that and blood constituents, and no relation between that and the score of food habit.

• 한국어병학회지
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• 제28권2호
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• pp.87-92
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• 2015

Juvenile Paralichthys olivaceus (mean length $17.3{\pm}2.2cm$, mean weight $46.5{\pm}6.3g$) were exposed for 10 days to tributyltin (TBT) at various concentrations (0, 1, 2, 4 and $8{\mu}g/L$). Hematological parameters, such as red blood cell (RBC) count, hematocrit (Ht), and hemoglobin (Hb) concentration, were considerably decreased by high TBT concentrations. In plasma constituents, inorganic components such calcium and magnesium were also significantly altered. Plasma calcium was notably decreased, whereas plasma magnesium was increased. The enzyme components, glutamic oxalate transaminase (GOT) and glutamic pyruvate transaminase (GPT), were significantly decreased by TBT exposure. The present findings suggest that TBT exposure can cause significant alterations in hematological parameters and plasma constituents of flatfish Paralichthys olivaceus.

• 한국가축번식학회지
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• 제17권1호
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• pp.21-25
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• 1993

We have previously shown that gossypol injection into the stroma of testis was found to effectively inhibit the process of spermatogenesis. In this study, properties and chemistry of blood were investigated weekly in ICR mouse after the injection of gossypol into the testicular stroma(5, 10 or 15mg per kg body weight). There were no significant differences in red blood cell(RBC), hematocrit, white blood cell(WBC), basophils, eosinophils and monocytes during first 4 weeks after injection of gossypol between treatments, but neutrophils increased and lymphocytes decreased, respectively(P<0.05). Total content of protein, albumin and globulin were not different, compared with control. However, the concentration of glucose after injection of gossypol increased significantly(P<0.05). In conculsion, the results of this study indicated that injection of gossypol into stroma of testis might affect both properties and chemistry of blood in mice.

• 동의생리병리학회지
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• 제26권3호
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• pp.344-350
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• 2012

Previously, we showed that Dangguisoo-san (DGSS), an herbal formula that has been traditionally used for the treatment of blood stagnation, is also applicable for inflammatory lung diseases. Activation of Nrf2, an anti-inflammatory transcription factor, and suppression of NF-${\kappa}B$, a pro-inflammatory transcription factor, were suggested as an underlying mechanism. However, the constituents responsible for these activities remain unidentified. To this end, we prepared the water extracts of the 9 constituents of DGSS and tested for their effect on Nrf2 by using an Nrf2-Luciferase reporter cell line and western blot analysis. Results show that Carthamus tinctorius L.(CT), one of the 9 constituents of DGSS, strongly activated Nrf2. Similarly, when measured the effect of the 9 constituents on NF-${\kappa}B$ by using an NF-${\kappa}B$-Luciferase reporter cell line and western blotting for nuclear p65, indicative of activated NF-${\kappa}B$, most constituents were capable of suppressing NF-${\kappa}B$ in various degrees. However, CT and Cyperus rotundus L. (CR) strongly suppressed NF-${\kappa}B$ activity elicited by LPS. Of note, CT activated Nrf2 and suppressed NF-${\kappa}B$ strongly as well. Our results contributes to corroborating the anti-inflammatory effects of DGSS by identifying CT and CR as two major herbs responsible for activating Nrf2 and suppressing NF-${\kappa}B$. These results suggest that CT and CR represent some of the effects of DGSS in the regulation of inflammation.