• The Journal of the Convergence on Culture Technology
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• v.2 no.3
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• pp.1-7
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• 2016

Infection of the disease that are propagated through a dead body of management and transportation must be very careful. Risk of infection that can occur between the deceased body and funeral directors, guideline of the preparation room and infection route of infection source has been studies in Korea. But the funeral director's working circumstances and infection blocking facility of the funeral home has not been studied in Korea. So we are investigated about the state of the working circumstances and Infection blocking facility within Metropolitan, Chungcheong and Gyeongsang regions in Korea. The result is as follows. The funeral directors have shown that there is difficult to get safe protection from infection. The personal hygiene of funeral directors and the infection blocking facility should be strengthened institutionally. We are thought to require more in-depth research about the working circumstances of funeral director and the infection blocking facility.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.22 no.12
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• pp.2644-2652
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• 1997

We ivestigate a two-stage queueing system which frequently arises in the study of overflow problems. A primary service facility consists of multiple primary queues where blocked calls are overflowed to a secondary queue. By approximating the input to the secondary queue with a two-state Markov Modulated Poisson Process (MMPP), we derive the blocking probability of the secondary queue. For the approximation, we employ the well-known Heffes' method and the SAM procedure.

• Journal of applied mathematics & informatics
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• v.31 no.1_2
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• pp.311-325
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• 2013

The effects of the moments of the interarrival time and service time on the system performance measures such as blocking probability, mean and standard deviation of the number of customers in service facility and orbit are numerically investigated. The results reveal the performance measures are more sensitive with respect to the interarrival time than the service time. Approximation for $GI/G/c$ retrial queues using $PH/PH/c$ retrial queue is presented.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.2
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• pp.390-397
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• 2017

The introduction of exotic fish species may reduce the number of native fish species and disturb the aquatic ecosystem. Therefore, measures to block and manage fish species are required. Accordingly, a fish species blocking system using bubbles was developed in this study to block exotic fish species. An experimental channel was produced and the possibility of blocking such exotic fish species was evaluated. The bubble generator is a system that produces a bubble curtain by generating air with an air compressor that blocks fish species. Bluegill, which is an exotic fish species in the country, was tested with this generator. The size of bluegill was between 0.10 m and 0.15 m and the depth of water was maintained at 0.70 m. The flow velocity of the experiment channel was classified into 3 levels (0.20 m/s, 0.10 m/s, and 0.05 m/s) considering the natatorial ability of the fish species. The results revealed that 70.07% of bluegill showed movements to swim upstream before applying the bubble, but it is considered that the ascending rate would be higher given that the fish species thinks downstream is a habitat and showed almost no movement. However, when the blocking facility was installed, most fish species showed movements to return to the downstream again by the bubble curtain, indicating a very high blocking effect. In particular, when the generating bubble was terminated, the fish species swam back to the upstream area very soon, so the fish species blocking effect using the bubble was excellent.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.10
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• pp.454-460
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• 2020

In recent years, the rapid increases in video distribution and viewing over the Internet have increased the risk of personal information exposure. In this paper, a method is proposed to robustly identify areas in images where a person's privacy is compromised and simultaneously blocking the object area by blurring it while rapidly tracking it using a prediction algorithm. With this method, the target object area is accurately identified using artificial neural network-based learning. The detected object area is then tracked using a location prediction algorithm and is continuously blocked by blurring it. Experimental results show that the proposed method effectively blocks private areas in images by blurring them, while at the same time tracking the target objects about 2.5% more accurately than another existing method. The proposed blocking method is expected to be useful in many applications, such as protection of personal information, video security, object tracking, etc.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.9
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• pp.76-83
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• 2017

Fish respond sensitively to light, so it is possible to develop fish management technology using this feature. In this study, we developed a light-based fish barrier and analyzed itsblocking effect using the difference in illuminance for the major fish species in Korea, bass and bluegill. The light was generated by a light emitting diode and the facility was installed vertically from the bottom. Considering the fish's ability to travel upstream, the flow rate was divided into three stages (0.2, 0.1, and 0.05 m/s). To prevent the learning effect, an experiment was carried out with fish that had rested for more than one day in a rearing tank. The experiment was carried out in such a way as tocompare the number of fish which travelled upstream after the introductionof the fish barrier and that of the fish which travelled upstream after itsremoval. It was also carried out after sunset to increase the effectiveness of the barrier. According to the results of the experiment, the fish blocking effect depending on the difference in illuminance was high and, overall, the blocking rate for bass was lower than that for bluegill. Based on the total size of the experimental population, the blocking rates for bass and bluegill were 96.33% and 99.00%, respectively. Based on the number of fish that travelled upstream, the blocking rates for bass and bluegill were 91.73% and 98.73%, respectively.

• Journal of Korean Institute of Industrial Engineers
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• v.37 no.2
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• pp.83-88
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• 2011

The effects of the moments of the retrial time to the system performance measures such as blocking probability, mean and standard deviation of the number of customers in service facility and orbit are numerically investigated. The results reveal some performance measures related with the number of customers in orbit can be severely affected by the fourth or higher moments of retrial time.

• The Journal of the Convergence on Culture Technology
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• v.3 no.1
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• pp.1-8
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• 2017

We are investigated about the state of the working circumstances and infection blocking facility within Metropolitan, Chungcheong and Gyeongsang regions in Korea. The result is as follows. The HAV vaccination rate is 35% and the HBV vaccination rate is 50% among the funeral directors. We expected that the infection risk of funeral directors was very high. Significantly, tuberculosis prevalence rate of funeral director was four times as high as the public. The wear rate of gown, mask, gloves showed relatively high than the others. The wear rate of individual protective equipments has decreased with work experience. The funeral directors have shown that there is difficult to get safe protection from infection. The personal hygiene of funeral directors and the infection blocking equipment should be strengthened institutionally. We are thought to recommend institutional support about infection management, individual protective equipment, vaccination of funeral director and guideline to avoid reversion to previous habitual behavior.

• Journal of Microbiology and Biotechnology
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• v.33 no.5
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• pp.591-599
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• 2023

Fisetin is a bioactive flavonol molecule and has been shown to have antioxidant potential, but its efficacy has not been fully validated. The aim of the present study was to investigate the protective efficacy of fisetin on C2C12 murine myoblastjdusts under hydrogen peroxide (H₂O₂)-induced oxidative damage. The results revealed that fisetin significantly weakened H₂O₂-induced cell viability inhibition and DNA damage while blocking reactive oxygen species (ROS) generation. Fisetin also significantly alleviated cell cycle arrest by H₂O₂ treatment through by reversing the upregulation of p21WAF1/CIP1 expression and the downregulation of cyclin A and B levels. In addition, fisetin significantly blocked apoptosis induced by H₂O₂ through increasing the Bcl-2/Bax ratio and attenuating mitochondrial damage, which was accompanied by inactivation of caspase-3 and suppression of poly(ADP-ribose) polymerase cleavage. Furthermore, fisetin-induced nuclear translocation and phosphorylation of Nrf2 were related to the increased expression and activation of heme oxygenase-1 (HO-1) in H₂O₂-stimulated C2C12 myoblasts. However, the protective efficacy of fisetin on H₂O₂-mediated cytotoxicity, including cell cycle arrest, apoptosis and mitochondrial dysfunction, were greatly offset when HO-1 activity was artificially inhibited. Therefore, our results indicate that fisetin as an Nrf2 activator effectively abrogated oxidative stress-mediated damage in C2C12 myoblasts.

• Molecules and Cells
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• v.45 no.12
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• pp.923-934
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• 2022

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have great potential in applications such as regenerative medicine, cardiac disease modeling, and in vitro drug evaluation. However, hPSC-CMs are immature, which limits their applications. During development, the maturation of CMs is accompanied by a decline in their proliferative capacity. This phenomenon suggests that regulating the cell cycle may facilitate the maturation of hPSC-CMs. Aurora kinases are essential kinases that regulate the cell cycle, the role of which is not well studied in hPSC-CM maturation. Here, we demonstrate that CYC116, an inhibitor of Aurora kinases, significantly promotes the maturation of CMs derived from both human embryonic stem cells (H1 and H9) and iPSCs (induced PSCs) (UC013), resulting in increased expression of genes related to cardiomyocyte function, better organization of the sarcomere, increased sarcomere length, increased number of mitochondria, and enhanced physiological function of the cells. In addition, a number of other Aurora kinase inhibitors have also been found to promote the maturation of hPSC-CMs. Our data suggest that blocking aurora kinase activity and regulating cell cycle progression may promote the maturation of hPSC-CMs.