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Neomycin Sulfate Nephrotoxicosis in Korean Black Goats (한국흑염소에 있어서의 Neomycin Sulfate에 의한 신증유발에 관하여)

  • Shim Won-Bo;Choi Hee-in
    • Journal of Veterinary Clinics
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    • v.6 no.2
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    • pp.319-327
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    • 1989
  • In order to study the effects of neomycin sulfate on the kidney of Korean black goats after dosing at 36mg/kg(A group) or 18mg/kg of body weight (B group) twice a day, serum chemical values(BUN, SCr), urinary enzyme(GGT) excretion and urinary analysis were checked and renal lesions were observed by light microscope. The proteinuria and granular casts were observed on the 5-6th day and 7th day of treatment with neomycin respectively in the A group. While these changes were observed on the 4th day and the 6th day respectively in one goat of the B group. Urinary GGT excretion began to increase from the 9th day and reached to maximum concentration on the 15th day of treatment with neomycin in the A group. Thereafter, GGT excretion began to decrease and reach to normal level on the 21th day. But GGT excretion increased on the 9th day in only one goat of the B group. Concentrations of BUN and SCr increased on the 12th day in the A group and in one goat of B group. The kidneys were swollen gross pathologically and the renal tubular epithelial cell changes were noticed histologically in the A group and in one goat of the B group. These changes were included degeneration with hyaline droplet formation, flattened epithelial cells and necrotic epithelium. Granular casts were showed in many tubular lumens. Prfesent results indicated that nephrotoxicosis would not occured in Korean black goats dosing with neomycin sulfate less that 36mg/kg of body weight a day.

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Clinicopathological Studies on the Experimentally Induced Nephrosis of Korea Black Goats (한국흑염소에서의 실험적 신증의 임상병리학적 연구)

  • Choi Hee-In;Sung Jai-Ki;Nam Tchi-Chou;Lee Chang-Woo;Lee Kyoung-Kap
    • Journal of Veterinary Clinics
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    • v.6 no.2
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    • pp.261-268
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    • 1989
  • In order to study the effects of administration of neomycin on the kidney of Korean black goats, 4.5(group A), 9(group B) or 14(group C) mg/kg, body weight of neomycin was injected intramuscularly turice a day for 84 days. On day 31, unilateral nephreotomy was performed in one animal of each group. The results were as follows: Serum neomycin concentrations were 8.7, 13.8, and 20.2 ${\mu}$g/ml 12 hours after injection. Serum BUN and creatinine concentration in nephreotomized goats, regardless of dosage, rapidly increased and came to peak on 3 days after, and then began to decrease to normal range, gradually, In non-nephrectomized goats, regardless of dosage, there was no notable change. In nephreotomized goats, PSP Tl/2 was delayed to the utmost 1 day after nephrectomy, regard-less of dosage, and then began to decrease to normal range, gradually in non-nephrectomized goats, there was not notable change in PSP T$\frac{1}{2}$. The intact kidney was markedly enlarged compared with the kidney of non-nephrectomized goats, but there was no microscopic change. It is concluded that administration of neomycin up to 14mg/kg body weight twice a day for 84 days was not nephrotoxic to the Korean black goats.

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Body Composition of Black Rockfish Sebastes schlegeli Fed on Diets Containing Different Levels of Turmeric Curcuma longa L. (울금(Curcuma longa L.) 첨가 사료 공급이 조피볼락(Sebastes schlegeli) 체성분에 미치는 영향)

  • Hwang, Jae-Ho;Rha, Sung-Ju;Han, Kyeong-Ho;Kim, Seon-Jae
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.46 no.5
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    • pp.540-545
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    • 2013
  • This study investigated the effect of diets supplemented with different levels (0, 1, 3, and 5 %) of turmeric Curcuma longa L. powder (TP) on the body composition of black rockfish Sebastes schlegeli. Fish weighing $10.05{\pm}0.44$ g were fed to apparent satiation twice daily for 8 weeks. Adding TP decreased crude lipid levels and increased crude protein and ash levels. Abundant fatty acids in the TP-added group were C16:0, C18:1 n-9 (cis), and C22:6 n-3. The major amino acids in samples were glutamic acid, aspartic acid, glycine, leucine, alanine, lysine, and arginine.

Current Level of Reproductive Performances in Japanese Black Cows

  • Uchida, Hiroshi;Kobayasi, Jin;Inoue, Tatsushi;Suzuki, Keiichi;Oikawa, Takuro
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.8
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    • pp.1098-1102
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    • 2002
  • A set of 313,169 reproduction records of Japanese Black cows calving between 1987 and 1996 were collected in nation widely Japan to investigate the current level of reproductive performances and the factors influencing the performances such as calving interval, first calving age, services per conception, calving difficulty, non-gestation period and gestation length. All the records of reproductive performances are outcome of artificial insemination. The means of first calving age, calving interval, non-gestation period and gestation length were 25.0 months, 389.9, 101.9 and 287.5 days, respectively. Services per conception were 1.41 and degree of calving difficulty was 1.07, which suggests most of the calving, did not need assistance. There were chronological tendencies that first calving age became younger while calving interval became longer. Differences in reproductive performance were found for seasons and calving numbers. Calving interval became shorter towards the fourth calving but became longer afterwards. The cows calving in May had the shortest calving interval followed by those in April and June and first calving age had a similar tendency. The cows with the standard body condition score showed more favourable reproductive performances compare with those with rather fatty or thin body condition scores.

Effects of Woori Black Pig Sire on Growth Performance, Body Shape, and Retail Cut Yield of Crossbred Pigs (우리흑돈 종모돈이 삼원교잡종 돼지의 성장, 체형 및 부분육 생산수율에 미치는 영향)

  • Choi, Yo Han;Min, Ye Jin;Jung, Hyun Jung;Jeong, Yong Dae;Kim, Jeong A;Cho, Eun Seok;Kim, Young Sin;Hong, Joon Ki
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.9
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    • pp.432-439
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    • 2020
  • To improve the relatively low economic efficiency of the Korean native pig, the Korean National Institute of Animal Science developed a novel pig breed, the Woori black pig (W), by crossing Korean native and Duroc (D) pigs. This study was conducted to evaluate the effects of W as a terminal sire on growth performance, body shape, and retail cut yield of crossbred pigs. By using a completely randomized design, 32 crossbred pigs were allotted to one of two treatment groups based on terminal sire. The two groups were LYD [(Landrace × Yorkshire) × D sire] and LYW [(Landrace × Yorkshire) × W sire]. The experimental assessments were conducted over 53 days. The terminal sire breed had no significant effect on body weight (BW) at d 53, or on BW gain, average daily gain, or days to reach a 90 kg body weight. Moreover, there were no significant differences in body length, body height, or chest depth between the two groups. However, there was a significant difference (p < 0.05) in backfat thickness between the LYD (17.29 mm) and LYW (18.96 mm) groups. Loin yield of crossbred pigs in the LYW group (13.11%) was significantly lower (p < 0.05) than that in the LYD group (13.85%). By contrast, the Boston butt yield was significantly higher (p < 0.05) in the LYW group (8.99%) than in the LYD group (8.21%). In conclusion, these results suggest crossbred pigs sired by a Woori black pig had growth performance, shape, and retail cut yield (except loin yield) Ed. Note: I assume the lower loin yield is a negative factor so I included this wording. similar to those sired by a Duroc pig. The results showed no overall negative effect Ed. Note: I assume the lower loin yield is a negative factor so I used this wording. on crossbred offspring, indicating the suitability of the Woori black pig as a terminal sire.

Geology and Occurrence of Black Sandstone and Black Shale Dimension Stones, Korea (흑색사암(오석)과 흑색셰일(청석) 석재자원의 지질과 산출유형)

  • Park Deok Won;Hong Sei Sun;Kim Chul Joo;Lee Choon Oh;Lee Byeong Tae;Yun Hyun Soo
    • Economic and Environmental Geology
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    • v.37 no.6 s.169
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    • pp.585-601
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    • 2004
  • A general study of domestic black sandstone and black shale quarries has not been made. For this reason it is difficult to know how the matter really stands. The objectives of this study are to achieve systematical and scientific study of the distribution, occurrences and rock quality of black sandstone and black shale resources exploited in existing quarries in the Boryeong area. The black sandstone bed survey was made from 54 mine claims on 4 sheets. In the area, 140 black sandstone and 22 black shale quarries were ascertained in 37 mine claims. The general development information data from that existing quarries were collected and synthesized. Among these black sandstone quarries for gravestones, monuments and black shale quarries for inkstone are in operation. Most of the black sandstone quarries were closed throughout the Gaewhari, Suburi, Seongjuri district in the investigated area even though these quarries had played a prominent part in the production of black sandstone. In view of commercial dimension stones, raw materials from black sandstone are classified as corestone and fresh rock body according to the characteristics of their occurrences and shape. Black sandstone beds are characteristically well-jointed and are particularly subdivided into cubic or quadrangular blocks in 3 joint sets. The colors of these black sandstones show medium dark $gray\~grayish$ black judging from the Rock Color Chart. The black sandstone beds which are intercalated in the Amisan, Jogeri, Baegunsa, Seongjuri Formations of the Daedong Supergroup are about $1\~10\;m$ in thickness.

Supplementary Effects of Black Rice (Oryza sativa L.) Aleurone Layer Extract on Body Fat, Serum Lipid, and Serum Hormone Levels in Ovariectomized Rats (흑미 호분층 추출물의 급여가 난소절제 흰쥐의 체내 지방, 혈중 지질 및 관련 호르몬 수준에 미치는 영향)

  • Choi, Bong-Kyoum;Nam, Song-Yee;Lee, Young-Min;Kim, Jung-Bong;Choe, Jeong-sook;Lee, Hae-Jeung;Lee, Sung-Joon;Lee, Sung-Hyen
    • The Journal of the Korea Contents Association
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    • v.15 no.9
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    • pp.599-605
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    • 2015
  • This study was conducted to evaluate suppressive effects of black rice aleurone layer extract (BRE) on body fat, serum lipid, and hormone levels in ovariectomized rats. The rats were divided into five groups (n=8/group): sham operated group (S); ovariectomized control group (OVX); ovariectomized group treated with isoflavone 10 mg/kg B.W. (IF); ovariectomized group treated with BRE 30 or 90mg/kg B.W. (BRE-30 or -90). High fat diet (45% calories from fat) was fed to all rats for 12 weeks. Body weight gain, body fat weight, and adiposity index increased in the OVX group, but they significantly decreased in IF or BRE supplementation. Serum triacylglycerol and leptin levels decreased in BRE groups while serum adiponectin level significantly increased compared to that of the OVX group. Hepatic total lipid, triglyceride, and cholesterol levels increased in the OVX group, but they decreased in BRE supplementation (p>0.05). These data suggest that black rice aleurone layer may be a useful food source to decrease obesity and its related diseases by modulating lipid metabolism in estrogen-deficiency model.

Comparison of Anesthetic Responses Induced by MZT and XZT Combinations at General Anesthesia for Laparoscopic Salpingectomy in Rearing Female Asiatic Black Bears (Ursus thibetanus)

  • Kang, Tae Ku;Kim, Ill-Hwa;Lee, Jun-Am;Park, So-Young;Hwang, Dae-Youn;Kang, Hyun-Gu
    • Journal of Veterinary Clinics
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    • v.36 no.6
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    • pp.306-313
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    • 2019
  • It is important to identify the most suitable anesthetic agent that has minimal side effects to be able to control and perform surgeries on bears. In this study, we examined and compared the induction and recovery times as well as the physiological changes occurring during anesthesia induced by medetomidine-zolazepam/tiletamine (MZT) and xylazine-zolazepam/tiletamine (XZT) at general anesthesia for laparoscopic salpingectomy in 326 female Asiatic black bears. The body temperature, heart rate, respiratory rate, and levels of PaO2 and EtCO2 were the physiological changes measured during surgical procedures in female bears after anesthesia. In addition, the levels of pO2, pCO2, and sO2 were measured using a portable blood gas analyzer. To induce recovery from anesthesia, bears anesthetized with MZT were intravenously administered atipamezole and bears anesthetized with XZT were intravenously administered yohimbine. The combination MZT, at dosages of 0.019 ± 0.001 mg/kg for medetomidine and 1.4 ± 0.1 mg/kg for ZT, or the combination XZT, at dosages of 2.0 ± 0.1 mg/kg for xylazine and 3.0 ± 0.1 mg/kg for ZT, proved to be reliable and effective in anesthetizing Asiatic black bears for a 40-min handling period for routine clinical procedures. The average anesthesia induction times were 16.5 ± 0.95 min for the bears in the MZT group and 12.0 ± 0.44 min for those in the XZT group. A significant difference was noted between the two drugs (P < 0.001) in terms of the average anesthesia induction time. The anesthesia induction time was shorter for bears with lower body weights than those with higher body weights (P < 0.05). The recovery time of MZT was significantly faster than that of XZT (11.3 ± 0.45 min vs. 18.5 ± 0.83 min) (P < .001). The bears anesthetized with MZT exhibited lower cardiopulmonary suppression than those anesthetized with XZT (P < 0.05). The body temperatures and EtCO2 of bears in the M ZT group were significantly lower than those in the XZT group as time progressed after anesthesia (P < 0.05). The average pO2 before the bears were supplied with oxygen was 64.8 ± 3.7 mmHg, but it increased to 211.5 ± 42.5 mmHg afterwards (P < 0.001). In conclusion, our results indicate that bears anesthetized with MZT have longer anesthesia induction time, shorter recovery time, slower heart and respiratory rates, and lower body temperatures and EtCO2 than those anesthetized with XZT. These findings suggest that XZT is preferable to MZT, warranting further research on its uses and clinical responses in bears.

Black Hair Follicular Dysplasia in a Shih Tzu (Shih Tzu 견에서 발생한 Black Hair follicular Dysplasia 일례)

  • Kim Sung-ryong;Kim Young-in;Seo Jeong-a;Park Ji-won;Jeong A-young;Lee Keun-woo;Oh Tae-ho
    • Journal of Veterinary Clinics
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    • v.22 no.2
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    • pp.157-159
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    • 2005
  • Two-month old male Shih Tzu weighing 2.1 kg was presented with alopecia in black-haired areas of the skin. The hair loss had been present since five weeks of age. There was no history of pruritus on any part of the body. No other symptoms had been recognized. Physical examination found no abnormalities other than hair loss. Skin examination showed marked alopecia of black-haired area of the body. The white areas appeared to have hair growth of normal density and texture. Affected pigmented areas showed no evidence of skin lesions. Skin scraping and fungal culture were negative. Microscopic examination of plucked black hairs showed marked pigment clumping in the remnants of the follicles and were mainly in telogen phase. But white hairs were normal in various stages of hair growth. The diagnosis of black hair follicular dysplasia was made based on the history, alopecia of the pigmented areas, the confinement of abnormalities to dark areas, and the normal unpigmented areas.

The Anti-Diabetic Effects and Nephroprotective Effect of Black Ginseng Prosapogenin Extract in Streptozotocin-Induced Mice (흑삼의 프로사포게닌 추출물이 Streptozotocin으로 유도된 당뇨 쥐에 대한 항당뇨 효과 및 신장보호 효과)

  • Kong, Ryong;Shon, Mi Yae;Seo, Yun Soo;Kang, Ok Hwa;Zhou, Tian;Kim, Do Yeon;Choi, Sung Hoon;Kwon, Dong Yeul
    • Korean Journal of Medicinal Crop Science
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    • v.24 no.2
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    • pp.115-120
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    • 2016
  • Background: This study examined the hypoglycemic and kidney protective effect of black ginseng in streptozotocin-induced diabetic mice. Methods and Results: Diabetes was induced by treating mice with streptozotocin (STZ) for four weeks. In vivo studies were performed in order to investigate the hypoglycemic effect of the black ginseng prosapogenin (GBG05-FF) extract. The body weight and blood glucose level were measured. Moreover, after the mice were sacrificed, the kidneys were isolated and histological changes were observed with hematoxylin and eosin staining. Blood urea nitrogen and creatinine levels were also measured. The results showed that administration of black ginseng increased body weight. Compared to blood glucose levels in STZ mice, blood glucose levels were reduced by 48% in STZ mice supplemented with 300 mg/kg of black ginseng, and by 69% in STZ mice supplemented with 900 mg/kg. Furthermore, histopathological examination of STZ mouse kidneys revealed, changes in the kidneys, epithelial cell damages, inflammatory cell infiltration and glomerulus hypertrophy. However, a significant reduction of glomerular water droplets (indicative of glomerulus hypertrophy) was observed in the kidneys of STZ mice supplemented with black ginseng extract. Conclusions: These results suggest that black prosapogenin (GBG05-FF) ginseng extract has a significant hypoglycemic effect and can be used as an anti-diabetic substance and renal protective agents as part of dietary supplements or novel drugs.