• Proceedings of the KAIS Fall Conference
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• 2003.06a
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• pp.219-221
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• 2003

This system is Emergency patient medical examination and treatment way through biosignal transmission to use PDA. Store measured biosignal that is stored to file to database by Application, This system helps doctor's treatment that transmit patient's biosignal data and patient's symptoms use wireless internet. ThenOffer more than safer medical treatment environment to a doctor and patient

• Journal of the Korea Institute of Military Science and Technology
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• v.16 no.6
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• pp.841-846
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• 2013

Recently, personal health monitoring system using intelligent biosensors and equipments has been realized. This system can be adopted for soldier's biosignal monitoring system. In this paper, we propose a soldier biosignal monitoring system using personal biosensors, such as the ECG sensors and accelerometer.

• Journal of the Ergonomics Society of Korea
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• v.29 no.1
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• pp.47-53
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• 2010

An analysis of biosignal and performance data collected during driving has increasingly employed in research to explore a human-vehicle interface design for better safety and comfort. The present study developed a protocol and a system to effectively analyze biosignal and driving performance measurements in various driving conditions. Electrocardiogram (ECG), respiration rate (RR), and skin conductance level (SCL) were selected for biosignal analysis in the study. A data processing and analysis protocol was established based on a comprehensive review of related literature. Then, the established analysis protocol was implemented to a computerized system so that immense data of biosignal and driving performance can be analyzed with ease, efficiency, and effectiveness for an individual and/or a group of individuals of interest. The developed analysis system would be of use to examine the effects of driving conditions to cognitive workload and driving performance.

• Journal of Biomedical Engineering Research
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• v.29 no.2
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• pp.164-171
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• 2008

Recently, many of hospitals have hurried to computerize the resulting data from medical devices, in order to introduce Electric Medical Record(EMR). In terms of the linkage between medical devices and hospital information systems, however, many difficulties have arisen due to some reasons such as the variety of prescription input, the format difference of the resulting data sheet, and the interface difference between medical devices from different companies. To solve these problems, many researches on standardization of the resulting data of medical devices have been performed. In this study, the linkage between hospital information systems and resulting datum in Electrocardiogram(ECG) generating biosignal waveform was tested by applying Medical waveform Format Encoding Rules(MFER) Version 1.02, which has more advantages than existing global standard. MFER viewer, in addition, was made to display the resulting data on a screen. The MFER viewer was tested and compared to the existing Scalable Vector Graphics (SVG) Viewer. The results showed that this method is more effective in the interface the data storage and application, because of simplicity and easiness in data applications. And the results show that the MFER is convenience and effective for physician. It is considered that the role of MFER as the interface in biosignal waveform including Electrocardiogram medical devices would expand in the near future.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.13 no.1
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• pp.1-15
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• 2019

Internet of Things (IoT) is commonly referred to as a future internet technology to provide advanced services by interconnecting physical and virtual things, collecting and using many data from them. The IoT platform is a server platform with a common architecture to collect and share the data independent of the IoT devices and services. Recently, oneM2M, the global standards initiative for Machine-to-Machine (M2M) communications and the IoT announced the availability of oneM2M Release 2 specifications. Accordingly, this paper presents a new oneM2M-compliant IoT platform called Mobius 2.0 and proposes its application to collect the biosignal data from wearable IoT devices for emotion recognition. Experimental results show that we can collect various biosignal data seamlessly and extract meaningful features from the biosignal data to recognize two emotions of joy and sadness.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1998.04a
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• pp.171-175
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• 1998

This work presents an estimation for stress status using biosignal and fuzzy theory. Stress is estimated by 'coin-build' experiment with two type, relax and stress status. The estimator uses five biosignals, fuzzy logic to combine these signals and physiological knowledge. The system was tested in 10 records of healthy indivisuals and acheived a template of a stress progress. This work presents an estimation for stress status using biosignal and fuzzy theory. Stress is estimated by 'coin-build' experiment with two type, relax and stress status. The estimator uses five biosignals, fuzzy logic to combine these signals and physiological knowledge. The system was tested in 10 records of healthy indivisuals and acheived a template of a stress progress.

• Journal of Satellite, Information and Communications
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• v.9 no.2
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• pp.80-84
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• 2014

As an integrated technology with IT and biomedical sciences, U-health offers various healthcare services without time and space limit. In order to make a proper diagnosis, doctors need two key technologies: biosignal measurement and high reliability communication technologies. In this paper, we introduce an implementation process of a bio signal system with using an electrocardiography(ECG) sensor, video, global positioning system(GPS), communication module and micro controller unit(MCU).

• Journal of Microbiology and Biotechnology
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• v.28 no.3
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• pp.439-447
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• 2018

The aromatic compound p-hydroxybenzoate (PHBA) is an important material with multiple applications, including as a building block of liquid crystal polymers in chemical industries. The cytochrome P450 (CYP) enzymes are beneficial monooxygenases for the synthesis of chemicals, and CYP53A15 from fungus Cochliobolus lunatus is capable of executing the hydroxylation from benzoate to PHBA. Here, we constructed a system for the bioconversion of benzoate to PHBA in Escherichia coli cells coexpressing CYP53A15 and human NADPH-P450 oxidoreductase (CPR) genes as a redox partner. For suitable coexpression of CYP53A15 and CPR, we originally constructed five plasmids in which we replaced the N-terminal transmembrane region of CYP53A15 with a portion of the N-terminus of various mammalian P450s. PHBA productivity was the greatest when CYP53A15 expression was induced at $20^{\circ}C$ in $2{\times}YT$ medium in host E. coli strain ${\Delta}gcvR$ transformed with an N-terminal transmembrane region of rabbit CYP2C3. By optimizing each reaction condition (reaction temperature, substrate concentration, reaction time, and E. coli cell concentration), we achieved 90% whole-cell conversion of benzoate. Our data demonstrate that the described novel E. coli bioconversion system is a more efficient tool for PHBA production from benzoate than the previously described yeast system.

• Journal of Microbiology and Biotechnology
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• v.30 no.8
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• pp.1207-1213
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• 2020

Aflatoxin B1 (AFB1) is a mycotoxin produced by Aspergillus flavus (A. flavus). AFB1 is reported to have high thermal stability and is not decomposed by heat treatment during food processing. Therefore, in this study, knowing that AFB1 is metabolized by cytochrome P450 (CYP), our aim was to develop a method to detoxify A. flavus-contaminated maize, under normal temperature and pressure, using Escherichia coli expressing human CYP3A4. First, the metabolic activity of AFB1 by recombinant human CYP3A4 was evaluated. As a result, we confirmed that recombinant human CYP3A4 metabolizes 98% of AFB1. Next, we found that aflatoxin Q1, a metabolite of AFB1 was no longer mutagenic. Furthermore, we revealed that about 50% of the AFB1 metabolic activity can be maintained for 3 months when E. coli expressing human CYP3A4 is freeze-dried in the presence of trehalose. Finally, we found that 80% of AFB1 in A. flavus-contaminated maize was metabolized by E. coli expressing human CYP3A4 in the presence of surfactant triton X-405 at a final concentration of 10% (v/v). From these results, we conclude that AFB1 in A. flavus-contaminated maize can be detoxified under normal temperature and pressure by using E. coli expressing human CYP3A4.

• Journal of the Korea Society of Computer and Information
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• v.15 no.12
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• pp.19-26
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• 2010

In this paper, we studied about the Embedded System of the biosignal measurement and analysis to sensibility evaluation in daily life for non-intrusive. This system is two kinds of measuring biosiganls(Electrocardiogram:ECG, Photoplethysmography:PPG) and analyzed by real-time wireless transmission to notebook PC using bluetooth for consistent and reliability of physiological way to assess continuously changing sensibility. Comparative studied of an autonomic nerve system activity ratio on characteristics frequency band of two kinds of biosignal analyzed frequency way using the Fast Fourier Transform(FFT) and Power Spectrum Density(PSD). Also the key idea of this system is to minimize computing of analysis algorithm for faster and more accurate to assess the sensibility, and the result of the visualization using graph. In this paper, we evaluated the analysis system to assess sensibility that measuring various situation in daily life using a non-intrusive biosignal measurement system, and the accuracy and reliability in comparison with difference of result by development analysis system.