• Macromolecular Research
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• 제14권1호
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• pp.73-80
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• 2006

Sulfonated poly(ethylene glycol) (PEG-$SO_{3}$) grafted polyrotaxanes (PRx-PEG-$SO_{3}$) were prepared in order to utilize the unique properties of PEG-$SO_{3}$ and the supramolecular structure of PRx, in which PEG-$SO_{3}$ grafted $\alpha$-cyclodextrins ($\alpha$-CDs) were threaded onto PEG segments in a PEG-b-poly(propylene glycol) (PPG)-b-PEG triblock copolymer (Pluronic) chain capped with bulky end groups. Some of the PRx-PEG-$SO_{3}$ demonstrated a higher anticoagulant activity in case of PRx-PEG-$SO_{3}$ (P 105), and compared with the control they showed a lower fibrinogen adsorption in PRx-PEG-$SO_{3}$ (F68) and a higher binding affinity with fibroblast growth factor. The obtained results suggested that polyrotaxane incorporated with PEG-$SO_{3}$ may be applicable to the surface modification of clinically used polymers, especially for blood/cell compatible medical devices.

• Macromolecular Research
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• 제12권4호
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• pp.379-383
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• 2004

Poly(ethylene glycol)s (PEGs) are unique in their material properties, such as biocompatibility, non-toxicity, and water-solublizing ability, which are extremely useful for a variety of biomedical applications. In addition, a variety of functional PEGs with specific functionality at one or both chain ends have been synthesized for many specialized applications. Surface modifications using PEG have been demonstrated to decrease protein adsorption and platelet or cell adhesion on biomaterials. Furthermore, PEGs having anionic sulfonate terminal units have been proven to enhance the blood compatibility of materials, which has been demonstrated by the negative cilia concept. The preparation of telechelic PEGs having a sulfonic acid group at one end and a polymerizable methacryloyl group at the other is an interesting undertaking for providing macromers that can be used in various vinyl copolymerization and gel systems. In this paper, preliminary results on the synthesis and polymerization behavior of a novel PEG macromer is described with the aim of identifying a biocompatible material for applications in various blood-contacting devices.

• 대한의용생체공학회:의공학회지
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• 제18권4호
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• pp.421-428
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• 1997

초전도양자간섭소자(SQUID)를 이용한 자장센서는 현재 개발된 자장센서중에서 감도가 가장 우수한 소자로서 인체의 두뇌에서 발생하는 매우 미약한 자장에 측정이 가능하다. 뇌자도측정은 현재 많이 사용되고 있는 전기적인 측정(뇌파, 뇌유발전위) 에 비해 공간분해능이 우수하고, fMRI나 PET에 비해서는 시간분해능이 우수하므로 뇌기능연구에 유용하게 사용될 수 있다. 본 연구에서는 뇌자도 측정을 위하여 4-채널 SQUID시스템을 개발하였다. 개발된 시스템의 주요 특징은 새로운 방식의 SQUID센서를 채택함으로서 간단한 회로로써 SQUID구동이 가능하도록 하였으며, 검출코일의 신뢰성을 향상시키기 위하여 집적화된 평면형 코일을 사용하였다. 외부 환경잡음을 소거하기 위하여 자기차폐실을 설치하였고, 개발된 SQUID 시스템을 이용하여 뇌의 청각령으로부터 발생하는 자기신호를 측정하였다.

• 대한의용생체공학회:의공학회지
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• 제34권1호
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• pp.1-7
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• 2013

According to the frequent use of mobile devices, risk of repetitive strain injury for the finger joints was increasing recently. The purpose of this study was to investigate the difference of muscular endurance limit of the thumb between adults and children. A total of thirty subjects (15 adults: $41.0{\pm}7.9$ years and 15 children: $9.5{\pm}2.7$ years) was recruited for this experiment. Maximum voluntary contraction (MVC) of the thumb was measured for 100 trials for each subject by using a push-pull gauge. From the maximum peak value obtained, three main factors (MVC, endurance limit, and fatigue index) were defined to quantify fatigue characteristics of the thumb flexor muscle. The experimental results showed that the mean of MVC, endurance limit, and fatigue index of the children were approximately 50% compared to the adults (p < 0.001). From the results of Pearson correlation test, the endurance limit was highly correlated with weight, age, hand length rather than height. Based on this study, children are more vulnerable to repetitive task using the thumb such as text/SNS messaging, gaming, and scrolling.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2006년도 하계종합학술대회
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• pp.1015-1016
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• 2006

The important parameters deciding the fluctuation of Accumulation style surgical operation of ventriculus laser beam are smoothing capacitor, frequency and he characteristics of laser resonator. In this thesis, we control the fluctuation of medical $CO_2C$ laser in realtime by changing Duty-Ratio of IGBT and switching frequency with fixed the smoothing capacitor to improve the fluctuation of laser beam. We detect the light on laser resonator using a CdS photo sensor to improve ripple factor of laser beam and feedback fluctuated signals refined by a band pass filter into the control circuit to stabilize fluctuation actively. There is much to be desired in the realtime controlling technique of the light on Accumulation style surgical operation of ventriculus laser discharge tube in electrical signal. We propose switching control technique with microprocessor and photo sensing technique by controlling switch devices optimum operation and feedback signals detected by a photo sensor into the laser power supply in order to improve ripple factor of the $CO_2$ laser beam.

• 대한의용생체공학회:의공학회지
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• 제18권3호
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• pp.205-210
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• 1997

본 시험조사는 정형외과, 신경외과, 재활의학과 등에서 경부 척추를 물리적으로 고정하는 데 널리 사용되고 있는 연성, 토마스, 미네르바 및 필라델피아 경추보조기의 물성을 조사하여 새로운 경추보조기를 고안하기위한 기초자료를 얻기 위하여 이루어 졌다. 인장강도는 토마스 보조기가 가장 우수했으며 지속적인 마모를 통한 재료 관통시험에서는 미네르바 보조기가 가장 우수한 내구력을 가진 것으로 나타났다. 이러한 결과로 미루어 볼 때, 에틸렌수지를 구조체로 사용하고 피부에 통기성을 부여하기 위해 재료에 다공성을 제공하는 것이 좋을 것으로 사료된다.

• 한국정보통신학회논문지
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• 제17권8호
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• pp.1940-1946
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• 2013

스마트 헬스케어 서비스(smart healthcare service)는 예방적 건강관리와 웰니스(wellness)를 위한 수요자 중심의 능동적 서비스 제공을 목표로 한다. 최근, 스마트 헬스케어는 스마트폰을 사용하여 기초체력 운동 지수, 섭취 칼로리, 심박 체크 등의 다양한 서비스를 제공할 수 있다. 그러나 미비한 개인건강기기 표준화로 아직까지 상용 가능한 서비스 모델이 없는 실정이다. 이에 본 논문에서는 산소포화도 측정계를 사용하여 Bluetooth HDP를 기반으로 ISO/IEEE 11073 표준을 지원하는 안드로이드 스마트 헬스케어 Manager를 설계, 구현하였다.

• 한국자동차공학회논문집
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• 제23권1호
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• pp.25-33
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• 2015

This paper presents the d-q axis equivalent circuit model of an interior permanent magnet (IPM) which includes the iron loss resistance. The model is implemented to be able to run in real-time on the FPGA-based HIL simulator. Power electronic devices are removed from the motor control unit (MCU) and a separated controller is interfaced with the real-time simulated motor drive through a set of proper inputs and outputs. The inputs signals of the HIL simulation are the gate driver signals generated from the controller, and the outputs are the winding currents and resolver signals. This paper especially presents iron loss prediction which is introduced by means of comparing the torque calculated from d-q axis currents and the desired torque; and minimizing the torque difference. This prediction method has stable prediction algorithm to reduce torque difference at specific speed and load. Simulation results demonstrate the feasibility and effectiveness of the proposed methods.

• 조명전기설비학회논문지
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• 제30권1호
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• pp.1-7
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• 2016

With a collimated $CO_2$ laser beam, the bidirectional current switching was realized in a two-terminal electronic device based on a highly resistive vanadium dioxide($VO_2$) thin film. A $VO_2$ thin film was grown on a $Al_2O_3$ substrate by a pulsed laser deposition method. For the fabrication of a two-terminal electronic device, the $VO_2$ thin film was etched by an ion beam-assisted milling method, and the $VO_2$ device, of which $VO_2$ patch width and electrode separation were 50 and $100{\mu}m$, respectively, was fabricated through a photolithographic method. A bias voltage range for stable bidirectional current switching was found by using the current-voltage property of the device measured in a current-controlled mode. The transient responses of bidirectionally switched currents were analyzed when the laser was modulated at a variety of pulse widths and repetition rates. A switching contrast was measured as ~3333, and rising and falling times were measured as ~39 and ~21ms, respectively.

• 한국전기전자재료학회논문지
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• 제31권1호
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• pp.11-18
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• 2018

Two-dimensional (2D) materials such as transition metal dichalcogenides have attracted tremendous scientific interests owing to their potential of solving the zero band-gap issue of graphene. In this work, the research areas and technology evolutionary dynamics of the 2D materials were identified using the scientometric method focusing on keyword mapping and clustering. The time-series analysis showed that the technological progress of 2D material is in the early growth period. The overlay mapping analysis were carried out to investigate the technology evolution of 2D materials with time. The strategic diagram of co-word analysis classifying the topological positions of keyword was derived to support the analysis results. It is conjectured that extensive research will be conducted widely on the application of 2D materials not only in electronic and optoelectronic devices, but also in various other fields such as biomedical applications, and that their development will be more rapid based on accumulated results of extant graphene research.