• Applied Biological Chemistry
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• 제41권8호
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• pp.563-567
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• 1998

Computer aided molecular modeling can help to predict the three dimensional structure of the polypeptide without the sample. The study on soybean Bowman-Birk protease inhibitor (SBI) is valuable, because it has been recently known that SBI possesses anticarcinogenic activities and immune-stimulating properties. SBI has several isoinhibitors, whose isolation and characterization were reported in 1990. Among these, DII inhibits trypsin only. The different inhibitory specificities cannot be explained only by their different primary sequences, but is possible with further assistance by the study on their different three dimensional structures. The study on the three dimensional structure of DII using homology method is reported in this paper.

• 전기학회논문지
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• 제59권12호
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• pp.2349-2351
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• 2010

Photo Acoustic Tomography (PAT) is a hybrid imaging modality which combines high contrast of optical imaging and spatial resolution of ultrasound imaging, thus it is suitable to image biological tissue noninvasively. Laser-induced photoacoustic signals were measured from a sample by means of an unfocused ultrasound transducer, then PAT image was reconstructed based on a universal back-projection algorithm. To evaluate the feasibility of our system, phantom test was performed, consequently, the PAT images obtained using our system showed highly analogous shape and volume with those of the phantom. This result demonstrated that our system can provide a powerful tool for imaging the substructure of biological tissue in non-invasive manner.

• Environmental Analysis Health and Toxicology
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• 제3권3_4호
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• pp.9-15
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• 1988

The word of stress crime from Latin language as stringere and it was used in medical fields from 1935. According to Selye, all the biological bodies reveal physilolgical changes when some stimulation exceed normal levels, and consequently the pituitary gland and adrenal systems are activated. Jacob expressed that stress is the loss of homeostasis by physical, chemical, and emotional stimulation. When biological organisms receive extreme stress the amount of catecholamine excretion are increase. Author investigated the catecholamine contents in rat urine after giving the low temperature stress, noise stress, and water immersion stress. The 24 hours rat urine was collected by adding 1 ml 6 N-HCl and the sample is passed through Bio-Rex 70 samples treatment column to extract catecholamine and detected the catecholamine with HPLC-fluorescence detetor. The highest epinephrine concentration was 67.14 ng in water immersion stress condition and the dopamine concentration of 221.37 ng was shown in the low temperature stress condition.

• 대한의용생체공학회:의공학회지
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• 제27권6호
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• pp.310-317
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• 2006

Extensive research with polarimetry and Mueller matrix has been done for chemical measurements and possible cancer detection. However, the effect of thermally denatured biological tissue on polarization changes is not well known. The purpose of this study is to characterize polarization changes in collagen due to thermal denaturation. The variations in polarized state caused by thermal damage were investigated by obtaining the Mueller matrix elements of collagen sample at multiple thermal damage levels. The changes in birefringence of denatured collagen were also investigated. This information could be used to determine the extent of thermal damage level of clinically heat treated tissues.

• Animal Systematics, Evolution and Diversity
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• nspc9호
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• pp.30-36
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• 2016

As a part of the commemorative joint faunal survey for the 30th anniversary of the Korean Society of Systematic Zoology, the molluscan fauna of Jindo Island was investigated based on sample collection from 6 localities from the 6 to the 8 of Jul 2016. A total of 114 molluscan species from 47 families were collected and identified. Among these, 42 species from 11 families are newly reported from Jindo Island and combining the previous records with the present study totals 157 species from 57 families. Distribution of species records indicates that marine biogeography of Jindo Island represent an overlapping zone for marine organisms which dwell in the Yellow sea and the southern sea areas of Korean waters.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.2459-2463
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• 2005

Optical coherence tomography (OCT) is high resolution medical imaging system which is obtaining image inside biological objects with non-destructive method. OCT system is based on Michelson interferometer with a reciprocating mirror in the reference arm and a biological object in the sample arm. The obtained OCT image suffers from a granular or mottled image, called speckle. Speckle is caused by random interferences between reflected coherence waves. In this paper, we propose effective speckle reduction method that uses wavelet transform. With wavelet domain image, sub-windowing and thresholding are performed. Finally, speckle reduction experiments for Misgurnus mizolepis skin and rat eye images are shown.

• 전기화학회지
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• 제10권2호
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• pp.88-93
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• 2007

Nano-sized Sn particles were coated with Ni-P layer using an electroless deposition method and their anodic performance was tested for lithium secondary batteries. Uniform coating layers were obtained, of which the thickness was controlled by varying the $Ni^{2+}$ concentration in the plating bath. It was found that the Ni-P layer plays two important roles in improving the anodic performance of Sn powder electrode. First, it prevents the inter-particle aggregation between Sn particles during the charge/discharge process. Second, it provides an electrical conduction pathway to the Sn particles, which allows an electrode fabrication without an addition of conductive carbon. A pseudo-optimized sample showed a good cyclability and high capacity ($>400mAh\;g^{-1}$) even without conductive carbon loading.

• Molecules and Cells
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• 제26권6호
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• pp.530-535
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• 2008

Optical signals based on Raman scattering, coherent anti-Stokes Raman scattering (CARS), and harmonic generation can be used to image biological molecules in living cells without labeling. Both Raman scattering and CARS signals can be used to detect frequencies of molecular vibrations and to obtain the molecular distributions in samples. Second-harmonic optical signals can also be generated in structured arrays of noncentrosymmetric molecules and can be used to detect structured aggregates of proteins, such as, collagen, myosin and tubulin. Since labeling techniques using chemical and biological reactions may cause undesirable changes in the sample, label-free molecular imaging techniques are essential for observation of living samples.

• Applied Biological Chemistry
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• 제25권3호
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• pp.182-188
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• 1982

일차아민과 반응하여 형광활성화합물을 형성하는 fluorescamine을 이용하여 어떤 시료중에 포함된 극미량의 trypsin inhibitor의 함량 또는 그 활성도를 측정하는 형광방법을 기술하였다. 세 가지 두류종실 즉 대두, 녹두 및 팥의 상대적 antitryptic activity 측정을 예로들어 본방법의 분석화학 우적수성을 여러 각도에서 검토하였던바, 효소반응속도론적 접근으로 이루어진 본방법은 동일한 접근으로 이루어진 기존의 흡광광도방법과 비교하여 측정감도는 대략 100배이상이였으며 casein과 같은 천연기질을 사용하는 경우에서는 실험과정이 보다 단순하여 빠른 방법으로 판정되었다.

• Biotechnology and Bioprocess Engineering:BBE
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• 제5권5호
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• pp.362-365
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• 2000

A rapid immunochromatographic assay kit using whole blood to screen hepatitis B surface antigen was developed and evaluated by using sera from 240 patients. The reference diagnosis was based on the results obtained with GENEDIA Anti-HBs Rapid kit which is very similar to the above kit except for the use of serum. The test demonstrated a good correlation with the reference immunochromatographic assay kit, that is, the sensitivity and the specificity of the kit was 100%, respectively. The rapid test kit using whole blood should be more convenient and useful for the diagnosis of hepatitis B virus because the kit does not need machines and time to prepare serum. In addition, this kit is safe from inadvertent infection during sample treatment because the blood is sterilized with hydrogen peroxide, eliminates the procedure required to prepare serum and reduces the possibility of exposure to infectious agents.