• Title/Summary/Keyword: Biological safety

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A Systematized Overview of Published Reviews on Biological Hazards, Occupational Health, and Safety

  • Alexis Descatha;Halim Hamzaoui;Jukka Takala;Anne Oppliger
    • Safety and Health at Work
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    • v.14 no.4
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    • pp.347-357
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    • 2023
  • Introduction: The COVID-19 pandemic turned biological hazards in the working environment into a global concern. This systematized review of published reviews aimed to provide a comprehensive overview of the specific jobs and categories of workers exposed to biological hazards with the related prevention. Methods: We extracted reviews published in English and French in PubMed, Embase, and Web of Science. Two authors, working independently, subsequently screened the potentially relevant titles and abstracts recovered (step 1) and then examined relevant full texts (step 2). Disagreements were resolved by consensus. We built tables summarizing populations of exposed workers, types of hazards, types of outcomes (types of health issues, means of prevention), and routes of transmission. Results: Of 1426 studies initially identified, 79 studies by authors from every continent were selected, mostly published after 2010 (n = 63, 79.7%). About half of the reviews dealt with infectious hazards alone (n = 38, 48.1%). The industrial sectors identified involved healthcare alone (n = 16), laboratories (n = 10), agriculture (including the animal, vegetable, and grain sectors, n = 32), waste (n = 10), in addition of 11 studies without specific sectors. The results also highlighted a range of hazards (infectious and noninfectious agents, endotoxins, bioaerosols, organic dust, and emerging agents). Conclusion: This systematized overview allowed to list the populations of workers exposed to biological hazards and underlined how prevention measures in the healthcare and laboratory sectors were usually well defined and controlled, although this was not the case in the agriculture and waste sectors. Further studies are necessary to quantify these risks and implement prevention measures that can be applied in every country.

Effects of perceptions of the importance of patient safety management and patient safety competency on patient safety management activities among nurses at unaccredited general hospitals (미인증 종합병원간호사의 환자안전관리 중요성 인식, 환자안전역량이 환자안전간호활동에 미치는 영향)

  • Ji-Yeong Park;Hanna Choi
    • Journal of Korean Biological Nursing Science
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    • v.26 no.1
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    • pp.60-69
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    • 2024
  • Purpose: This descriptive research study attempted to determine how general hospital nurses' awareness of the importance of patient safety management and patient safety competency affected patient safety management activities. Methods: From September 13 to 26, 2022, a survey was administered to 230 ward nurses who provided direct care to patients at five non-accredited general hospitals being evaluated for accreditation located in metropolitan cities. The collected data were analyzed with descriptive statistics, the t-test, one-way analysis, the Scheffé test, Pearson correlation coefficients, and hierarchical regression using SPSS for Windows version 26.0. Results: In total, 221 (96.1%) respondents were female. The average age was 32.2 years, and the average clinical experience was 3.5 years; 196 participants (85.2%) were general nurses. Patient safety competency (β = .44, p < .001), awareness of the importance of safety management (β = .31, p < .001), and medication error experience (β = -.15, p = .002) all had statistically significant associations with patient safety management activities. The explanatory power of these variables for patient safety management activities was 50.7%. Conclusion: This study confirmed that patient safety competency, awareness of the importance of patient safety management, and experience with medication errors significantly influenced patient safety management activities.

A Study on the Biological Hazards Exposure for Waste Handling Industries in Korea (국내 폐기물 취급업의 생물학적 인자 노출실태)

  • Park, Hyunhee;Park, Hae Dong;Lee, Inseop
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.22 no.4
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    • pp.265-275
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    • 2012
  • Objectives: The aim of this study was to investigate the distribution patterns and exposure concentrations of biological hazards in waste handling industries. Methods: We selected 3 recyclable waste sorting plants(RWS), 2 food recycling plants(FR), 1 landfill area(LA) and 1 waste incineration plant(WI). Total airborne bacteria and fungi were measured with single stage impactor and gelatin filters. Endotoxin and glucan were measured with polycarbonate filters in total and respirable dust. Results: The geometric mean of airborne bacterial concentration was the highest in FR($3,273CFU/m^3$), followed by LA, RWS, and WI as 1,334, 934, and $860CFU/m^3$. The fungal concentrations were 6,031, 5,052, 3,307, and $713CFU/m^3$ in RWS, WI, FR, and LA, respectively. By process, WI pit showed the highest concentrations of bacteria, fungi, and endotoxin, followed by inside of bulldozer in LA. The indoor to outdoor ratios of bacteria, fungi, endotoxin and glucan were 2.3, 4.0, 2.3, and 5.0 in RWS, 29.5, 4.9, 7.6, and 5.0 in FR, 5.3, 8.7, 26.8, and 9.5 in WI, respectively. Conclusions: We found that biological hazards, specifically bacteria in FR, fungi in RWS and endotoxin in WI pit and bulldozer at LA, should be controlled to prevent worker's respiratory diseases.

A STUDY ON BIOLOGICAL MARKERS FOR THE ASSESSMENT OF GENOTOXICITY AND OXIDATIVE DAMAGE IN CHROMIUM EXPOSED WORKERS.

  • Maeng, Seung-Hee;Hiroshi Kasai;Yu, Il-Je;Lee, Byung-Moo;Lee, Jong-Yoon;Lee, Kwon-Seob;Chung, Ho-Keun;Chung, Hai-Won
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.121-122
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    • 2001
  • According to the epidemiological studies in chromium workers, hexavalent chromium is associated with the risk of lung cancer. Genotoxicity such as chromosome aberration, and cellular oxidative damages by reactive oxygen species produced by hexavalent chromium exposure may play an important role in the carcinogenesis process. We investigated the availabilities of several kinds of biological markers to assess the genotoxicity and oxidative damages from chromium exposure in Korean chromium plating workers.(omitted)

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Disaster and Safety Response Management on the Bioterrorism and Biological War (생물테러 및 생물학전의 재해안전 대응방안에 대한 고찰)

  • Wang, Soon Joo;Byun, Hyun Joo
    • Journal of the Society of Disaster Information
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    • v.3 no.2
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    • pp.119-128
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    • 2007
  • A bioterrorism attack is the deliberate release of viruses, bacteria, or other agents used to cause illness or death in people, animals, or plant. These agents are found in nature, but it is possible that they could be changed to increase their ability to cause disease, make them resistant to current medicines, or to increase their ability to be spread into the environment. Terrorists may use biological agents because these agents can be extremely difficult to detect and do not cause illness for several days. Some bioterrorism agents, like smallpox virus, can spread from person to person, like anthrax, can not. From these agents, we discussed the characteristics of biological agents and national safety regulation on the weapons of mass destruction including bioterrorism.

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Evaluation of the Suitability of Establishing Biological Exposure Indices of Styrene

  • Choi, Ah-rum;Im, Sung-guk;Lee, Mi-young;Lee, Se-Hoon
    • Safety and Health at Work
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    • v.10 no.1
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    • pp.103-108
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    • 2019
  • Background: This study was designed to provide logical backgrounds for the revision of biological exposure indices (BEIs) for styrene exposure in Korea. In order to investigate the correlation between airborne styrene and biological exposure indices, we measured urinary mandelic acid (MA) and phenylglyoxylic acid (PGA) in workers exposed to styrene occupationally, as well as airborne styrene at workplaces. Methods: Surveys were conducted for 56 subjects. The concentrations of airborne styrene and urinary metabolites of styrene were measured in 36 workers who were occupationally exposed to styrene, and in 20 controls. Air samples were collected using personal air samplers and analyzed by gas chromatography. Urine samples were collected at the end of the shift and analyzed by high performance liquid chromatography. Results: The geometric mean concentration of airborne styrene was 9.6 ppm. The concentrations of urinary MA, PGA, and MA+PGA in the exposure group were 267.7, 143.3, and 416.8 mg/g creatinine, respectively. The correlation coefficients for correlation between airborne styrene and MA, PGA, and MA+PGA were 0.714, 0.604, and 0.769, respectively. The sum of urinary MA and PGA corresponding to an exposure of 20 ppm styrene was 603 mg/g creatinine. Conclusion: The correlation of the sum of urinary MA and PGA with airborne styrene was better than the correlation of each individual urinary determinant. It is considered appropriate to amend the concentration of urinary MA+PGA to 600 mg/g creatinine as a BEI, which corresponds to an airborne styrene concentration of 20 ppm in Korea.

Global Estimates on Biological Risks at Work

  • Jukka Takala;Alexis Descatha;A. Oppliger;H. Hamzaoui;Catherine Brakenhielm;Subas Neupane
    • Safety and Health at Work
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    • v.14 no.4
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    • pp.390-397
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    • 2023
  • Introduction: Biological risks are a major global problem in the workplace. The recent COVID-19 pandemic has highlighted the need for a more comprehensive understanding of the biological risks at work. This study presents data on both communicable infectious biological agents and noncommunicable factors leading to death and disability for the year 2021. Methods: We followed the methodology established by the International Labour Organization (ILO) in their past global estimates on occupational accidents and work-related diseases. We used relevant ILO estimates for hazardous substances and related population attributable fractions derived from literature, which were then applied to World Health Organization mortality data. The communicable diseases included in the estimates were tuberculosis, pneumococcal diseases, malaria, diarrheal diseases, other infectious diseases, neglected tropical diseases, influenza associated respiratory diseases and COVID-19. Noncommunicable diseases and injuries considered were Chronic Obstructive Diseases (COPD) due to organic dusts, asthma, allergic reactions and risks related to animal contact. We estimated death attributable to biological risk at work and disability in terms of disability adjusted life years (DALYs). Results: We estimated that in 2022, 550,819 deaths were caused by biological risk factors, with 476,000 deaths attributed to communicable infectious diseases and 74,000 deaths caused by noncommunicable factors. Among these, there were 223,650 deaths attributed to COVID-19 at work. We calculated the rate of 584 DALYs per 100,000 workers, representing an 11% increase from the previous estimate of the global burden of work-related disabilities measured by DALYs. Conclusion: This is a first update since previous 2007 ILO estimates, which has now increased by 74% and covers most biological risks factors. However, it is important to note that there may be other diseases and deaths are missing from the data, which need to be included when new information becomes available. It is also worth mentioning that while deaths caused by major communicable diseases including COVID-19 are relatively rare within the working population, absences from work due to these diseases are likely to be very common within the active workforce.

Creating a Workplace Handbook of Biologically Hazardous Agents (사업장의 생물학적 유해인자 편람 작성 연구)

  • Rim, Kyung-Taek
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.24 no.1
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    • pp.14-37
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    • 2014
  • Objectives: Since information on biological factors in the workplace are currently lacking, I wanted to create a handbook of these factors that would be viewable at a glance as a means to more effectively prevent occupationally-infected diseases. Proper information on biological hazards in the workplace allowing the appropriate recognition of the harmful factors is desperately needed. Methods and Results: In this study, I intended to create a high-utility handbook of biologically hazardous agents in the workplace. To ensure its effectiveness, information and references about biologically hazardous agents in the workplace were analyzed and classified and pathogen safety data sheets(PSDS) sourced from the Public Health Agency of Canada were included. I intended to make it accessible from the point of view of workers and their employers. A more effective classification system of occupational infectious diseases is presented, and biologically hazardous agents were classified according to occupations, industries, infectious diseases, and so on. The handbook consists of 60 major kinds of biologically infectious occupational factors that are expected to be generated in workplaces in Korea, and are focused on practical utility. The pathogen safety data sheets(PSDS) of 192 species were also included. To allow more effective management, domestic and foreign laws and regulations are presented. Conclusions: This case report presents general information on the history and contents of the handbook and PSDS, it will also be useful in workplaces if download from the homepage of OSHRI, KOSHA(oshri.kosha.or.kr/bridge?menuID=901).