• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.4
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• pp.603-607
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• 2011

The purpose of this study is to investigate the effects of Carthami Flos on interstitial cells of Cajal in the gastrointestinal tract. Many regions of the tunica muscularis of the gastrointestinal (GI) tract display spontaneous contraction. These spontaneous contractions are mediated by periodic generation of electrical slow waves. Recent studies have shown that the interstitial cells of Cajal (ICCs) act as pacemakers and conductors of electrical slow waves in gastrointestinal smooth muscles. We investigated the cytotoxicity activity, antioxidant activity, and pacemaking activity. The cytotoxicity activity was measured by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay. Antioxidant activities were determined by DPPH (1.1-diphenyl-2-picrylhydrazyl) radical scavenging capacity assay and DCFH-DA (2,7-dichlorofluorescein diacetate) method. The effects of Carthami Flos on the pacemaker potentials in cultured ICCs from murine small intestine were investigated by using whole-cell patch-clamp techniques at $30^{\circ}C$. The addition of Carthami Flos (5, 10, $30{\mu}g$/ml) depolarized the resting membrane potentials in a concentration dependent manner. These results suggest that the GI tract can be targets for Carthami Flos, and their interaction can affect intestinal motility.

• Bulletin of the Korean Chemical Society
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• v.18 no.12
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• pp.1324-1327
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• 1997

• The Journal of the Society of Korean Medicine Diagnostics
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• v.10 no.1
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• pp.46-53
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• 2006

Magnetocardiography provides non-invasive three-dimensional electroanatomical imaging of cardiac electrophysiology. The aim of this study is to find the index for using the indicator of magnetocardiography. An object of this study is 214 papers registered on www.pubmed.com. The index used in magnetocardiography is the interval, morphology, amplitude and integrals of QRS complex, P wave, T wave. The current density and electric field map are used, too. A new try of the index is LAS, W-HEAD, Relative Smoothness index(RS index) etc.

• Journal of the Korean Chemical Society
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• v.36 no.5
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• pp.770-779
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• 1992

Five (alkynylethoxymethylene)$Fe(CO)_4 complexes (1) are prepared through the reaction of Fe(CO)_5$ with alkynyllithium (R = n-Pr, cyclohexyl, t-Bu, trimethylsilyl, Ph) and subsequent O-ethylation of the resulting acyl anion complexes with ethyl fluorosulfonate. In the reactions of trimethylsilyl-substituted alkynylcarbene complex (1d) with 8 open-chain 1,3-dienes, ({\eta}^3-vinylcarbene)Fe(CO)3 complexes (2) are obtained as major products.

• Journal of the Korean Academy of Esthetic Dentistry
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• v.24 no.1
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• pp.68-74
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• 2015

The growing of healthy aged edentulous peoples in these days increases the demands of denture which is excellent in function and aesthetic. The Biofunctional Prosthetic System(BPS) is being introduced as a curriculum in a large number of schools in the United States, Europe and Japan. Each stages of BPS are standardized and systematized, on this account BPS is the system that even less experienced clinicians is able to produce highly satisfactory denture for patients. Additionally, the combination of BPS and suction mechanism of mandibular complete denture would make it possible to produce stabilized mandibular denture during oral function. The purpose of this article is to describe a process of producing fuctionally and aesthetically outstanding denture by using BPS combined with mandibular suction mechanism.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.6
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• pp.443-450
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• 2015

The purpose of this study was is to understand how the network pharmacology databases of traditional medicine in China are established and provide suggestion for successful implementation in Traditional Korean Medicine. We searched for network-pharmacology-related TCM Databases provided on the internet, and analysed their contents. Then, we compared herbs related to Sasang with herbs of the TCM Databases. We chose 8 network-pharmacology-related TCM Databases. They shared information about compounds, herbs, formulae, drugs, targets and diseases, and provided interaction networks between these components. In comparison with herbs related to Sasang, TCMSP Database did not have information about 99 herbs in total, and 25 herbs included in major Sasang formulae. The implications and recommendations for Traditional Korean Medicine researches were discussed. Based on the results of this primary study, more related studies should be carried out in the future.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.20 no.1
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• pp.1-13
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• 2016

Objectives The aim of this study is to develop diagnostic and assessable questionnaires for cervical movement system impairment syndromes. Methods We reviewed the previous study and literature, and organized various checkable items for differential diagnosis of four different cervical movement system impairment syndromes. Next, we selected items which can be developed as questionnaire items. Finally, we conducted a face validity study with twelve Korean medical doctors and carried out survey research to evaluate the importance score of the items with three experts. Results We developed a diagnostic and assessable questionnaire as follows: 9 items for cervical extension syndrome; 5 items for cervical flexion syndrome; 9 items for cervical rotation syndrome. By conducting 2 rounds of survey research, we were able to bridge the differences in the importance score of each item. Conclusions A questionnaire for the diagnosis and assessment of movement system impairment syndromes was developed. This questionnaire holds promising applications for objective diagnosis and assessment of cervical movement system impairment syndromes. This tool may also be used for detecting the sub-health status of musculoskeletal systems.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.14 no.1
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• pp.111-118
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• 2010

Objective : The study was performed to evaluate the effect of Kinesio taping on pain of Left hip joint. Methods : A 35-year-old, female patient who suffers from pain of left hip joint by brain tumor was treated by Kinesio taping therapy. The improvement of the patient's pain of left hip joint was evaluated by Visual Analog Scale(VAS), Faces Pain Rating Scale, McGill Pain Questionnaire(MPQ), and Pain Rating Score(PRS). Result : During the 9 days with Kinesio taping, VAS and Pain Rating Scale were decreased slightly. But Faces Pain Rating Scale and McGill Pain Questionnaire showed no change. Conclusions : The result suggests that Kinesio Taping was effective treatment to pain but not intensive. Further study is needed to evaluate the significancy of this report.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.14 no.2
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• pp.25-42
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• 2010

Background and purpose: The chronic diseases caused by lifestyle are on the increase. This study aims to review the eating habits as etiological factors and related symptoms from the perspective of Korean medicine. In this process, we will make a proposal on the treatment of the lifestyle related diseases. Methods: We studied the sentences about the eating habits and related diseases in Donguibogam Results and Conclusions: 1. The eating habits as etiological factors are overeating, irregular eating, late-night foods, fatty & heavy foods, cold foods, alcohols, etc. 2. The diseases caused by the eating habits are not limited to the gastrointestinal diseases(stomachache, vomiting, diarrhea, etc) but include the non-gastrointestinal diseases(edema, arthralgia, anal diseases, eye diseases, ear diseases, diabetes, cancers, etc.) 3. In the treatment of the diseases caused by the eating habits, the special regard should be paid to the etiological factors.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.2
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• pp.195-201
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• 2015

The aim of the study is to investigate the anti-cancer effects of Scutellaria barbata in AGS human gastric adenocarcinoma cells. MTT (3-[4, 5-dimethylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide) assay and caspase 3 or 9 activity assay were carried out to examine cell death with Scutellaria barbata. To elucidate the inhibitory effects of Scutellaria barbata, cell cycle (sub-G1) analysis and mitochondrial membrane potential were performed in AGS cells after 24 h incubation with Scutellaria barbata. Scutellaria barbata induced apoptosis in AGS cells by using the MTT assay, the sub-G1 analysis and mitochondrial membrane potential assay. The stronger inhibition effects of AGS cell growth was observed by application of Scutellaria barbata combined with several anti-cancer drugs (paclitaxel, 5-fluorouracil, cisplatin, ectoposide, doxorubicin and docetaxel) in comparison to the application of Scutellaria barbata or anti-cancer drugs. Our findings provide insight into unraveling the effects of Scutellaria barbata in human gastric cancer cells and developing therapeutic agents against gastric cancer.