• 대한한방내과학회지
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• 제43권2호
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• pp.184-190
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• 2022

Objectives: This study aims to report the clinical efficacy of Korean medical treatment of a patient with nonalcoholic fatty liver disease accompanied by obesity and dyslipidemia. Methods: A 52-year-old man with nonalcoholic fatty liver disease, obesity, and dyslipidemia was treated with Saenggangunbi-tang extract from November 3, 2021 to January 8, 2022. During the treatment period, the patient also undertook exercise and maintained a hypocaloric diet to reduce body weight. Changes were observed in the patient's symptoms, laboratory findings, such as liver enzymes and lipid profiles, and bioelectrical impedance analyzer results. Results: After taking Saenggangunbi-tang extract for approximately two months, with concomitant adjustments to exercise and diet, the serum levels of liver enzymes and triglyceride were decreased and the patient's body weight, body mass index, hepatic steatosis index, and visceral fat area were also reduced. In addition, symptoms including fatigue and dyspepsia improved. Conclusion: This study suggests that Saenggangunbi-tang extract with exercise and a regulated diet could be a helpful treatment strategy for managing nonalcoholic fatty liver disease with metabolic disorders.

• 대한한방내과학회지
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• 제42권2호
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• pp.207-214
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• 2021

Objectives: This study aimed to identify whether herbal medicine improves the clinical symptoms and abnormal blood tests of a patient with fatty liver accompanied by hypertriglyceridemia. Methods: A 44-year-old man with fatty liver and hypertriglyceridemia was prescribed Saenggangunbi-tang from July 20, 2020, to November 11, 2020, to reduce fatigue and to improve laboratory findings, such as liver enzymes and the lipid profile. We observed changes in symptoms, serum levels of liver enzymes, and the lipid profile during about 4-month treatment. We also recorded changes in the bioelectrical impedance analyzer findings during that time. Results: In this case study, an approximately 4-month treatment with Saenggangunbi-tang led to considerable improvement in laboratory findings and visceral fat area. In particular, the patient experienced a noticeable decrease in triglyceride levels compared with the baseline parameters of the first visit. In addition, no side effects-including weight gain and liver enzyme increases-were observed during treatment. Conclusion: This study suggests that appropriately prescribed herbal medicine is a therapeutic option to manage fatty liver combined with hypertriglyceridemia.

• 대한한방부인과학회지
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• 제35권1호
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• pp.1-11
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• 2022

Objectives: Management of the postpartum period is important for the health of mothers, and postpartum edema is one of the management targets. In this study, the relationship between the value measured by the device and the postpartum edema sensation was examined to explain the subjective sensation of the mother as an objective value. Methods: Data from 54 cases provided by 24 mothers within 6 weeks postpartum were used in the study. The degree of postpartum edema sensation was measured using a visual analog scale (VAS), and the effect of VAS changes on the body edema index and weight change before and after childbirth was estimated through linear regression analysis. Results: As a result of the regression analysis, when the edema sensation of the mothers VAS increased by 1 point, the Inbody edema index increased by 0.002 points (p=0.000, R²=0.272), and when the VAS increased by 1 point, the weight gain increased by 0.99 kg compared to before pregnancy (p=0.000, R²=0.243), and when VAS increased by 1 point, weight loss decreased by 0.56 kg compared to just before childbirth (p=0.004, R²=0.136). Conclusions: The results of this study, in which the edema sensation of postpartum mothers was statistically significantly related to the edema index and weight change before and after childbirth, showed that the edema sensation complained by the mother could be used as an evaluation index for postpartum edema management in the future.

• Tuberculosis and Respiratory Diseases
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• 제86권4호
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• pp.272-283
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• 2023

Background: In patients with chronic obstructive pulmonary disease (COPD), decreased muscle mass is a frequently encountered comorbidity in clinical practice. However, the evaluation of muscle mass in patients with COPD in real-world practice is rare. Methods: We retrospectively reviewed the electronic medical records of all patients with COPD who underwent bioelectrical impedance analysis at least once between January 2011 and December 2021 in three hospitals. Then, we analyzed the performance rate of muscle mass measurement in the patients and the correlation between muscle mass, clinical parameters, and COPD prognosis. Results: Among the 24,502 patients with COPD, only 270 (1.1%) underwent muscle mass measurements. The total skeletal muscle mass index was significantly correlated with albumin, alanine transaminase, and creatinine to cystatin C ratio in patients with COPD (r=0.1614, p=0.011; r=0.2112, p=0.001; and r=0.3671, p=0.001, respectively). Acute exacerbation of COPD (AE COPD) was significantly correlated with muscle mass, especially the truncal skeletal muscle mass index (TSMI) in males (r=-0.196, p=0.007). In the multivariate analysis, TSMI and cystatin C were significant risk factors for AE COPD (hazard ratio, 0.200 [95% confidence interval, CI, 0.048 to 0.838] and 4.990 [95% CI, 1.070 to 23.278], respectively). Conclusion: Low muscle mass negatively affects the clinical outcomes in patients with COPD. Despite its clinical significance, muscle mass measurement is performed in a small proportion of patients with COPD. Therefore, protocols and guidelines for the screening of sarcopenia in patients with COPD should be established.

• 대한통합의학회지
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• 제12권2호
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• pp.1-10
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• 2024

Purpose : Sarcopenic obesity is associated with adverse health consequences in females. Nevertheless, there has been limited research on the hazardous components and prevailing rates of sarcopenic obesity among younger women. This study aimed to identify the hazardous components and prevailing rates of sarcopenic obesity in younger females. Methods : This study utilized data based on 2008~2011 from the Korea National Health and Nutrition Examination Surveys by the centers for disease control and prevention. The analysis was concentrated on a subset of 1,520 women aged between 30 and 39 years of age. The participants answered a questionnaire to gather demographic information. They then underwent a physical examination to measure the human detention variables, which was conducted utilizing bioelectrical impedance analysis. The blood pressure and blood laboratory tests were determined using established laboratory protocols for evaluating blood parameters. Results : This study included 1,520 patients aged 30~39 years old. The mean age of the participants was 34.97 (years)±2.74 and the overall prevailing rate was 1.84 %. The hazard components in human dimensions were the height, weight, body mass index (BMI), waist circumference (WC) and skeletal muscle mass index (SMI). The hazard components in biochemical and blood pressure were high fasting glucose, increased triglyceride, elevated total cholesterol, high systolic blood pressure, and increased diastolic blood pressure with p-values <.05. Conclusion : This study examined the hazardous components and prevailing rates of sarcopenic obesity in younger women living in the community. The results contribute to the current body of knowledge on sarcopenic obesity and shed light on possible hazardous components in a younger female population. Based on these findings, there should be increased health and medical attention towards the prevention, management, and health promotion related to reducing risk factors for sarcopenic obesity in younger women.

• Clinical Nutrition Research
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• 제12권4호
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• pp.245-256
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• 2023

A randomized, double-blind, placebo-controlled trial was conducted to confirm whether collagen peptide supplementation for 12 week has a beneficial effect on body fat control in older adults at a daily physical activity level. Participants were assigned to either the collagen group (15 g/day of collagen peptide) or the placebo group (placebo drink). Body composition was measured by bioelectrical impedance analysis (BIA) and dual-energy X-ray absorptiometry (DEXA). In total, 74 participants (collagen group, n = 37; placebo group, n = 37) were included in the final analysis. The collagen group showed a significant reduction in total body fat mass compared with the placebo group, as evidenced by both BIA (p = 0.021) and DEXA (p = 0.041) measurements. Body fat mass and percent body fat of the whole body and trunk reduced at 12 weeks compared with baseline only in the collagen group (whole body: body fat mass, p = 0.002; percent body fat, p = 0.002; trunk: body fat mass, p = 0.001; percent body fat, p = 0.000). Total fat mass change (%) (collagen group, -0.49 ± 3.39; placebo group, 2.23 ± 4.20) showed a significant difference between the two groups (p = 0.041). Physical activity, dietary intake, and biochemical parameters showed no significant difference between the groups. The results confirmed that collagen peptide supplementation had a beneficial effect on body fat reduction in older adults aged ≥ 50 years with daily physical activity level. Thus, collagen peptide supplementation has a positive effect on age-related changes.

• 정신신체의학
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• 제7권2호
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• pp.213-225
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• 1999

서론 : 본 연구는 아동의 놀이 습관, 기질, 부모 및 가족 환경적 요인이 아동의 비만에 미치는 영향을 체계적으로 연구하여, 임상에서 비만아동 및 비만 성인을 치료할 때 활용하며 정확한 부모교육의 지침을 마련하고, 소아비만을 예방하는 대책을 강구해 보고자 하였다. 대상 및 방법 : 연구 대상은 서울과 천안 소재의 유치원에 다니는 만 4세에서 6세 아동 중 본 연구를 위해 고안한 설문지, 가정환경척도, 부모용 기질평가척도를 모두 답하고 신장, 체중 및 체지방율 측정이 가능했으며 특별한 과거력이 없는 260명이었다. 대상 아동들의 비만도는 한국소아의 신장별 체중 백분위의 50 퍼센타일을 이용하여 비만도(obesity index, 이하 OBI)를 계산하여 비만도가 20% 이상을 비만으로 정의하였고, 체지방 측정기기인 Bioelectrical Impedance Fatness Analyzer로 측정한 체지방율이 30% 이상인 경우를 비만으로 정의하였다. 결과 : 총 대상 아동 260명중 비만으로 측정된 25명을 비만군으로 나머지 235명을 정상체중군으로 평가하였고, 비만군의 평균 체지방율은 $32.0{\pm}2.4%$이었고, 정상체중군은 $22.4{\pm}2.9$ 이었으며, 비만도는 유의한 차이를 보였다(p<0.01). 비만아와 정상체중아의 부모의 BMI, 학력, 직업, 월평균소득을 비교한 결과 비만아의 아버지와 어머니가 모두 유의하게 높은 교육 수준을 보였고(p<0.05). 비만아의 어머니가 직업을 가진 경우가 유의하게 많았다(p<0.05). 비만아의 어머니가 유의하게 높은 BMI를 보였다(p<0.05). 월 평균 소득은 비만아동의 가정에서 높았으나, 통계적으로 유의한 차이를 보이지는 않았다. 대상 아동들의 놀이 형태를 관찰한 결과 비만아에서 TV나 비디오 시청 시간이 유의하게 길었으나(p<0.05). TV나 컴퓨터를 이용한 오락시간, 독서시간 및 장난감 가지고 노는 시간은 유의한 차이가 없었다. 정상체중군에서 실외놀이 시간이 긴 경향을 보였다(p<0.1). 부모용 기질 평가 설문지의 결과 활동성에서 비만아동이 정상체중아에 비해 유의하게 적은 활동성을 나타내었고(p<0.05), 비만아와 정상체중아에서 가정환경척도의 각 소척도를 비교해 본 결과 비만아의 가정에서 성취지향성, 지적-문화적 지향성, 도덕적-종교적 강조 소척도들의 점수가 유의하게 높았다(p<0.05). 부모의 BMI, 부모의 학력, 월평균 소득, 비만 아동의 놀이 습관, 기질의 각 소척도 및 가정 환경척도의 각 소척도들과 비만 아동의 체지방율의 상관 관계를 살펴본 결과, TV 시청 시간이 길수록, 아동의 활동성이 적을수록, 가정환경 척도 중 성취지향적이고 지적 문화적 지향적일수록, 아버지의 학력이 높을수록, 어머니의 학력이 높을수록, 아동의 체지방율이 높았다(p<0.05). 어머니의 BMI가 클수록, 가정의 평균 월수입이 높을수록, 아버지의 BMI가 클수록, 비만 아동의 체지방이 증가하는 경향을 나타내었다(p<0.1). 결론 : 결론적으로 비만한 아동은 기질특성상 저 활동성이며. TV 시청 시간이 길었다. 비만아동의 부모들은 높은 교육 수준을 보였으며 비만 아동의 어머니는 BMI가 높았고, 직업을 가진 경우가 많았다. 비만아의 가정에서 성취지향성, 지적-문화적 지향성, 도덕적-종교적 강조 소척도들의 점수가 유의하게 높았다. 가정 요인이 아동의 비만에 미치는 것은 단순한 것이 아니고 유전적 요인과 동시에 행동적 요인, 심리적 요인의 복합적인 영향을 준다고 볼 수 있다. 따라서 비만 아동을 치료시 아동 뿐 아니라 가족 모두의 참여와 변화가 중요하다고 볼 수 있다.

• 한국산학기술학회논문지
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• 제17권6호
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• pp.226-232
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• 2016

본 연구는 비만 노인여성을 대상으로 아쿠아로빅 운동을 적용한 후 신체조성 및 혈중지질의 개선효과를 알아보고 노인운동프로그램에 관한 다각적인 기초자료를 제공하는데 목적이 있다. 실험참가자들 (n=31)은 12주 동안 주 3회 60분의 아쿠아로빅 운동을 Borg의 운동자각도 12-13의 강도로 실시하였다. 신체조성은 inbody의 생체전기저항분석법을 사용하여 측정하였고 채혈된 혈액에서 혈중지질 (고밀도지단백(HDL), 저밀도지단백(LDL), 중성지방(TG)와 총콜레스터롤(TC))을 분석하였다. 자료의 분석은 대응 t-test를 이용하였고 유의수준은 0.05로 설정하였다. 아쿠아로빅 운동 후 체지방량과 허리둘레는 유의하게 감소하였고 (p < 0.05) 혈중지질 중 LDL (p < 0.05), TG (p < 0.001), 그리고 TC (p < 0.05)은 유의하게 감소하였다. 이상과 같은 결과를 볼 때 아쿠아로빅 운동은 신체조성과 혈중지질에 긍정적인 방향으로 변화시켰으며, 지방대사의 활용을 높여 지질분해의 향상과 신체조성을 증진시키고 고지혈증의 위험성을 낮출 것으로 생각된다. 따라서 아쿠아로빅 운동이 지상에서의 유산소 운동 및 저항 운동을 대체할 수 있는 유용한 운동이라 할 수 있다.

• 대한지역사회영양학회지
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• 제12권1호
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• pp.40-49
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• 2007

This study was done to investigate the health-related habits, dietary intakes and serum lipid levels in overweight and obese women by body mass index(BMI). Subjects were 137 pre-menopausal women aged 19 to 49 years. They were divided by 3 groups, overweight($23{\leqq}BMI<25$), obese($25{\leqq}BMI<30$) and morbidly obese($BMI{\geq}30$) according to their BMI. Body composition was determined by bioelectrical impedance analysis(BIA) method. Dietary intakes were examined by 3-day record method and nutrient intakes were analyzed by the Computer Aided Nutritional analysis program for professionals(CAN-pro 3.1). Serum lipid levels were measured using automatic biochemical analyzer(Selectra E). The average age, height weight and BMI of subjects were 31.7 years old, 159.3cm, 69.4kg, and $27.4kg/m^2$, respectively. Their average consumption of energy were 1712kca1 and 86.4% of estimated energy requirement(EER). Their mom ratio of carbohydrate:protein:fat was 55.2:14.6:30.2. Particularly, the fat consumption of subjects tended to be elevated with increasing BMI. There was no significant difference in nutrient intakes among 3 groups. But the mom intakes of Ca, Fe, vitamin C and Na of all the subjects were 70.1%, 81.2%, 75.7% of recommended intake(RI) and 258.9% of adequate intake(AI), respectively, The intakes of vegetables and seaweeds were significantly higher in morbidly obese group while the intake of fruits was higher in overweight group compared to the other groups. Serum lipid analysis showed that there were no significant differences in the levels of total cholesterol, triglyceride and LDL-cholesterol among the groups. But the serum HDL-cholesterol level of the overweight group was significantly higher than that of the other groups. LDL-/HDL-cholesterol ratio and AI index were significantly higher in the morbidly obese group compared to the other groups. In addition, The systolic blood pressure of morbidly obese group was significantly higher compared to the other groups. Overall data suggest that morbidly obese women have to more concern about reducing systolic blood pressure and nm lipid levels by decreasing their fat consumption and salt intakes as well as loosing body fat. In addition, all the subjects participated in this study have to be careful about their meals and health-related behaviors in order to prevent obesity-related chronic diseases.

• 대한한방소아과학회지
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• 제24권2호
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• pp.99-111
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• 2010

Objectives The objectives of this study were to evaluate the correlations between the indices of obesity and percentage body fat by bioelectrical impedance analysis(BIA). Also, this study was designed to define the cut off values of percentage body fat by BIA which would represent BMI and degree of obesity in order to detect overweight and obesity in preschool children. Methods The height and weight of 683 children aged four to six years old were measured. Also, percentages of body fat were measured by BIA. Results There were high correlations between the boy's body fat percentages and degree of obesity(r=790). Also, there were high correlations between the girl's body fatpercentages and BMI(r=778). The cut off values of body fat percentage, which would correspond to those of BMI percentiles, were calculated by ROC curve analysis. To classify as an overweight, the correspondent cut off values of body fat percentage were 19.55% in boys and 22.35% in girls. For obesity, the cut off values were 28.80% in boys and 27.60% in girls. The cut off values of body fat percentage, which would correspond to degree of obesity were calculated by ROC curve analysis. To classify as an overweight, the correspondent cut off values of body fat percentage were 19.75% in boys and 22.35% in girls. For obesity, the cut off values were 29.05% in boys and 28.75% in girls. Conclusions According to the BMI criteria by the Korean pediatrics society in 2007, the most appropriate cut off values of body fat percentage in for four to six years old children were follows; for boys, 19.55% considered as overweight, and 28.80% as obese while for girls, 22.35% considered as overweight and 27.60% as obese. According to suggested degree of obesity criteria, the most appropriate cut off values of body fat percentage in for four to six old children were were follows; For boys, 19.75% was considered as overweight, and 29.05% as obesity. For girls, 22.35% was considered as overweight, and 28.75% as obese.