• Proceedings of the Korean Society of Applied Pharmacology
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• 2000.04a
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• pp.6-7
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• 2000

Recently, free radicals such as active oxygen species, nitric oxide, etc are believed to be one of the key substances in physiological and pathological, toxicological phenomena, and oxidative damages, and all organism have defencing system against such as free radicals. Formation and extinction of free radicals may be regulated through bio-redox system, in which various enzymes and compounds should be involved in very complicated manner. Thus, direct and non-invasive measurement of in vivo free radical reactions with living animals must be essential to understand the role of free radicals in pathophysiological phenomena. Electron spin resonance spectroscopy (ESR) is very selective and sensitive technique to detect free radicals, but a conventional ESR spectrometer has large detect in application to living animals, since high frequent microwave is absorbed with water, resulting in generation of high fever in living body. In order to estimate in vivo free radical reactions in living whole animals, we develop in vivo ESR-CT technique using nitroxide radicals as spin probes. Nitroxide radicals and their reduced forms, hydroxylamines, are known to interact with various redox systems. We found that! ! the signal decay due to reduction of nitroxyl radicals is influenced by aging, inspired oxygen concentration, ischemia-referfusion injury, radiation, etc. In the present paper, I will introduce in vivo ESR technique and my laboratory recent results concerning non-invasive evaluation of free radical reactions in living mice.

• Journal of Korea Multimedia Society
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• v.18 no.2
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• pp.128-137
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• 2015

Blood oxygen saturation ($SpO_2$) is so important to be called bio-signal of the fifth. The measurement of blood oxygen saturation based on broad-ban light source has advantages of simple testing facility and easy understanding. This paper proposes a LabVIEW program which measures blood oxygen saturation based on broad-band light source. It combines LabVIEW and MATLAB, utilizing different light absorptions of oxyhemoglobin and deoxyhemoglobin in the visual wavelength range of 450nm-750nm to determine blood oxygen saturation. In order to improve accuracy through reducing the impact of hand shaking, the probe is fixed to the motor stage and then move a constant distance between the probe and the sample to be measured. Experimental results show that the proposed method noticeably increases the accuracy and saves time compared with the conventional methods.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.1 no.1
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• pp.13-19
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• 2007

In this study, diagnostic algorithm was suggested to diagnose quantitatively the degree of the stress urinary incontinence. The bio-signal measurement system was developed to measure the contraction pressure of the pelvic floor muscle and diagnostic parameters were drawn out by analyzing the contraction pressure data. Statistical evaluations were done to classify the diagnositc parameters by order that relationship is high. The diagnostic algorithm that was able to diagnose degree of the urinary incontinence as quantitatively was realized from the high relationship parameters.

• Journal of Biomedical Engineering Research
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• v.32 no.2
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• pp.85-92
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• 2011

Bioluminescence imaging (BLI) is the most sensitive animal imaging technique for molecular imaging research. Generally, highly sensitive CCD is used to detect an optical probe introduced in a living mouse. However, in many cases, the light signal emitted from a probe is too small to detect because it is scattered and attenuated by the tissue prior to being detected. The problem is that scattering and attenuation not only inhibit accurate measurement but also make image quality down. Thus we introduced a new method to reduce noise by using property of CCD and method to improve image quality of bioluminescence image by using two steps Gaussian blurring.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38B no.2
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• pp.105-114
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• 2013

Expansion and growth of body information monitoring service based on WBAN technology speeds up technological evolution in bio-signal detection and measurement, real time monitoring of vital sign and telemedicine control. It is essential for taking action against such technological evolution that newest technology trend and standardization issue should be included in designing and materializing body-information monitoring system strategically to secure preceding technology and to preoccupy market. This paper investigates and analyzes technological trend & issues, and suggests task to take action technologically.

• Journal of Institute of Control, Robotics and Systems
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• v.13 no.3
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• pp.205-209
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• 2007

Today, there are research trends about the wearable sensor device that measures various bio-signals and provides healthcare services to user using e-Health technology. This study describes the wearable sensor glove using pulse-wave sensor, conducting fabric and embedded system. This wearable sensor glove is based on the pulse-wave measurement system which is able to measure the pulse wave signal in much use of oriental medicine on the basis of a research trend of e-Health system.

• International Journal of Internet, Broadcasting and Communication
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• v.10 no.2
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• pp.51-59
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• 2018

Health care has attracted a lot of attention, recently due to an increase in life expectancy and interest in health. Various biometric data of the user are collected by using the air pressure sensor, gyro sensor, acceleration sensor, and heart rate sensor to perform the Smart Health Care Activity Tracker function. Basically, smartphone application is made and tested for biometric data collection, but the Arduino platform and bio-signal measurement sensor are used to confirm the accuracy of the measured value of the smartphone. Use the Google Maps API to set user goals and provide guidance on the location of the user and the points the user wants. Also, the basic configuration of the main UI is composed of the screen of the camera, and it is possible for the user to confirm the forward while using the application, so that accident prevention is possible.

• Journal of Satellite, Information and Communications
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• v.9 no.2
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• pp.80-84
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• 2014

As an integrated technology with IT and biomedical sciences, U-health offers various healthcare services without time and space limit. In order to make a proper diagnosis, doctors need two key technologies: biosignal measurement and high reliability communication technologies. In this paper, we introduce an implementation process of a bio signal system with using an electrocardiography(ECG) sensor, video, global positioning system(GPS), communication module and micro controller unit(MCU).

• Proceedings of the Korea Information Processing Society Conference
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• 2013.11a
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• pp.593-595
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• 2013

유비쿼터스 컴퓨팅은 IT기술을 기반으로, 의료 도시환경 건축 의류 등 사회 전반적인 분야로 확대되고 있다. 특히, 의료 기술의 발전과 고령인구의 증가, 삶의 질 향상에 대한 사람들의 욕구는 점점 헬스케어 산업의 중요성을 부각시켜주고 있다. 본 논문에서는 사용자 생체정보 측정을 위해 통신이 가능한 디지털 의류를 제작하여 생체신호를 측정할 수 있는 시스템을 제안하였다. 디지털 의류는 심전도 센서, 디지털 실, 모듈을 통해 구성되어 있으며 이를 안드로이드 어플리케이션을 통하여 스마트폰과 통신하도록 개발 하였다.

• Proceedings of the Korea Information Processing Society Conference
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• 2021.05a
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• pp.551-552
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• 2021

본 논문에서는 촬영한 피부 영상(얼굴, 손 등)을 이용한 생체신호(맥박, 호흡, 혈압, 체온 등) 측정 S/W 기술을 제안한다. 기존의 생체신호 측정 기술은 다양한 센서(PPG, 압력 센서, 혈압계, 체온계 등)가 탑재된 측정 장치를 이용하여 상태를 측정하고 이를 진단하는 연구들이 진행되어 왔다. 각 각의 생체신호를 측정하기 위해서는 별도로 구비된 측정 장치들을 이용하여 개별적으로 생체신호를 측정하고 확인하여야 한다. 제안된 기술은 스마트 디바이스에 생체신호 측정 S/W의 설치만으로 카메라로 촬영한 피부 영상의 피부 관심 영역에서 계산된 색상 데이터를 이용하여 다양한 생체신호를 언제 어디서나 실시간으로 측정할 수 있으며, 생체신호 측정 성능 평가 결과 맥박수 2.63%, 호흡수 5.98%, 이완기 혈압 2.48%, 수축기 혈압 5.23% 및 체온 0.25%의 오차율이 계산되었다.