• Title/Summary/Keyword: Bio-medical Engineering

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The Study About Attenuation of Scatter Ray According to Distance Inverse Square Law at General Projection (일반촬영 시 거리역자승법칙에 따른 산란선 감약에 관한 연구)

  • Jeon, Min-Cheol;Lim, Hyun-Soo;Han, Man-Seok
    • Journal of radiological science and technology
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    • v.34 no.3
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    • pp.183-188
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    • 2011
  • We studied the optimal location where the radiation dose of radiological technologists is minimally measured. The measured scatter dose has been compared with the distance inverse square law. We measured the primary X-ray with different tube conditions (60, 70, 81 and 90 kVp) and distances (60, 120 and 180 cm). The scatter ray has been measured with various locations (42.5, 52.4 and 62.4 cm for front and back side, 0 to 60 cm with 10 cm interval for left and right side). The results of this study showed that the dose of primary X-ray was attenuated to 20.52 (27.20%), 28.58 (25.20%), 38.82 (26.32%) and 48.20 mR (26.27%) for each tube voltages at 120 cm. In addition, The dose were 7.06 (8.91%), 9.90 (8.73%), 13.64 (9.25%) and 16.60 mR (9.05%) at 180 cm. As for the scatter in front and back side, the attenuated dose were 0.15 mR (23.09%) and 0.15 mR (22.08%) at 120 cm, and 0.07 mR (10.43%) and 0.06 mR (8.83%) at 180 cm. Scatter was decreased in third quadrant. Therefore, it is recommended that radiological technologists should keep long distance from the object.

Metabolic Changes in Pericontusional Edematous Areas in Mild Head Injury Evaluated by Proton MRS (경도 두부외상 환자에서 뇌좌상주위 부종영역에서의 자기공명분광법을 이용한 대사변화)

  • Hong, Sang-Su;Son, Byung-Chul;Cho, Byung Gil;Kim, Euy-Nyeng;Kim, Bum-Soo;Park, Chun-Kum;Choe, Bo-Young;Kim, Moon-Chan;Kang, Joon-Ki
    • Journal of Korean Neurosurgical Society
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    • v.29 no.9
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    • pp.1233-1237
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    • 2000
  • Objectives : In order to evaluate the metabolic changes associated with pericontusional edematous area in mild head injury, proton magnetic resonance spectroscopy(1H-MRS) was performed in mild head injury patients (initial GCS score 13-15) with focal brain contusion. Methods : Seven head injury patients with initial GCS 13-15(3 males and 4 females : age range 15-65 years, mean age 33 years) have underwent 1H-MRS evaluations. The patients were examined within 7 days after injury(n=7) and 2 months after injury(n=5). The region of interest(ROI) was selected in the edematous area adjacent to traumatic brain contusion upon T2-weighted MR images and a corresponding region of the contralateral hemisphere (ROC, region of contralateral corresponding hemisphere) was examined as well. The metabolic ratios of NAA/Cr and lactate/Cr were compared between ROIs, ROCs and control values. Results : In initial NAA/Cr ratios, the values of ROIs were significantly lower than those of the controls(p=0.009), but there was no difference either between ROIs and ROCs(p=0.410) or between ROCs of patients and the control (p=0.199). In lactate/Cr ratios, the ROIs in all seven patients and the ROCs in two showed increased lactate signals. The lactate/Cr ratios of the ROIs were significantly elevated as compared to those of the ROCs(p=0.02) and the control(p=0.015). In two months follow-up, lactate signals were absent or significantly reduced(p=0.015). In no patients, clinical or radiological deterioration has been observed. Conclusion : Our 1H-MRS results demonstrate that there are significant ischemic changes in pericontusional edematous areas as indicated by elevated lactate signals in the patients with mild head injury. But there were no consistent neural loss or dysfunction in these area. There findings suggest that pericontusional edematous areas can be vulnerable to secondary brain insults even in the patients with mild head injury.

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Induction of Demyelination of Neuronal cells by Sindbis Virus (Sindbis Virus에 의한 뉴런세포의 탈수초의 유도)

  • Sa, Young-Hee;Kim, Hyun Joo;Kweon, Tae Dong;Kim, Ji-Young;Lee, Bae Hwan;Hong, Seong-Karp
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2018.05a
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    • pp.584-587
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    • 2018
  • Many viruses including mouse hepatitis virus, corona, measles, and sidbis viruses are known as causative virus of inducing demyelination which means destruction of myelination in nervous system of mice. The purpose of this study is to investigate processing of myelination by co-culture of Schwann cells and neuronal cells and demyelination induced by infection of sindbis virusin rat. Schwann cells and neuronal cells from dorsal root ganglion (DRG) in embryos (E16) of rat were cultured in vitro respectively. The purified neuronal cells with anti-mitotic agents and purified Schwann cells were co-cultured. After that, infection of sindbis virus into this myelinated co-culture system was performed. Myelination and demyelination process were observed using antibody of myelin basic protein meaning presence of myelination.We identified myelination and demyelination processing using antibody of peripheral myelin protein 22 (PMP 22) meaning presence of myelinated neuron. This study was supported by the Basic Research Program through the National Research Foundation (NRF) funded by the Ministry of Science, ICT & Future Planning (NRF-2015R1C1A1A01053484 and 2017R1A2B3005753).

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Conservative Genes of Less Orthologous Prokaryotes (Orthologs 수가 적은 원핵생물들의 보존적 유전자)

  • Lee, Dong-Geun
    • Journal of Life Science
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    • v.27 no.6
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    • pp.694-701
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    • 2017
  • Mycoplasma genitalium represents the smallest genome among mono-cultivable prokaryotes. To discover and compare the orthologs (conservative genes) among M. genitalium and 14 prokaryotes that are uncultivable and have less orthologs than M. genitalium, COG (clusters of orthologous groups of protein) analyses were applied. The analyzed prokaryotes were M. genitalium, one hyperthermophilic exosymbiotic archaeon Nanoarchaeum equitans, four intracellular plant pathogenic eubacteria of Candidatus Phytoplasma genus, and nine endosymbiotic eubacteria of phloem- and xylem-feeding insects. Among 367 orthologs of M. genitalium, 284 orthologs were conservative between M. genitalium and at least one other prokaryote. All 15 prokaryotes commonly have 29 orthologs, representing the significance of proteins in life. They belong to 25 translation-related, including 22 ribosomal proteins, 3 subunits of RNA polymerase, and 1 protein-folding-related. Among the 15 prokaryotes, 40 orthologs were only found in all four Candidatus Phytoplasma. The other nine Candidatus, all endosymbionts with insects, showed only a single common COG0539 (ribosomal protein S1), representing the diversity of orthologs among them. These results might provide clues to understand conservative genes in uncultivable prokaryotes, and may be helpful in industrial areas, such as handling prokaryotes producing amino acids and antibiotics, and as precursors of organic synthesis.

Comparison in the usage of the Public Cremation Facilities Located in Seoul through the Online Reservation Service of Ehaneul Funeral Information System (e하늘장사정보시스템 온라인 예약서비스를 통한 서울특별시 공설화장시설의 지역별 이용 현황 비교)

  • Choi, Jae-sil;Kim, Jeong-lae
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.18 no.2
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    • pp.125-131
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    • 2018
  • The analysis and comparison on the usage of public cremation facilities located in Seoul through online reservation service of ehaneul funeral information system by area from Jan. 1, 2011 to Dec. 31, 2017 showed that among 314,877 in the number of bodies using the facilities, 225,828 (or 71.7%) belonged to Seoul citizens and 89,049 (or 28.3%) belonged to people living in other area than Seoul, such as Goyang city, Gyeonggi-do and other local governments. Therefore, there appeared that the Seoul citizens could not get the timely cremation service but instead extended the funeral service to 4 to 5 days or had to go to the remote area for cremation. This trend gets severe every year. To solve these problems, it is recommended that Seoul city government makes effort of constructing or expanding the public cremation facilities in cooperation with other local government of the area whose residents show high rate of using Seoul public cremation facilities and that Seoul city government expands or builds its own public cremation facilities in mid- and long-term. In addition, the local government of other area around Seoul needs to expand their use rate of their own (4) public cremation facilities or raise the creation fee for the residents from other areas, thus trying to dispersing and controlling the demand for the cremation.

Vapor Recognition Using Image Matching of Micro-Array Sensor Response from Portable Electronic Nose (휴대용 전자 후각 장치에서 다채널 마이크로 센서 신호의 영상 정합을 이용한 가스 인식)

  • Yang, Yoon-Seok
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.48 no.2
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    • pp.64-70
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    • 2011
  • Portable artificial electronic nose (E-nose) system suffers from noisy fluctuation in surroundings such as temperature, vapor concentration, and gas flow, because its measuring condition is not controled precisely as in the laboratory. It is important to develop a simple and robust vapor recognition technique applicable to this uncontrolled measurement, especially for the portable measuring and diagnostic system which are expanding its area with the improvements in micro bio sensor technology. This study used a PDA-based portable E-nose to collect the uncontrolled vapor measurement signals, and applied the image matching algorithm developed in the previous study on the measured signal to verify its robustness and improved accuracy in portable vapor recognition. The results showed not only its consistent performance under noisy fluctuation in the portable measurement signal, but also an advanced recognition accuracy for 2 similar vapor species which have been hard to discriminate with the conventional maximum sensitivity feature extraction method. The proposed method can be easily applied to the data processing of the ubiquitous sensor network (USN) which are usually exposed to various operating conditions. Furthermore, it will greatly help to realize portable medical diagnostic and environment monitoring system with its robust performance and high accuracy.

A Problem of Disqualified Fee Imposition Standard in Public Cremation Facilities on Internet Reservation of e-Haneul Funeral Total Information System and an Improvement Proposal (공설화장시설 사용료 부과기준 부적정이 e-하늘 장사종합정보시스템 인터넷 예약에 미치는 문제점 및 개선방안)

  • Choi, Jae-sil;Kim, Jeong-lae
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.16 no.3
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    • pp.163-172
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    • 2016
  • This study conducts an analysis of a problem on internet reservation of e-haneul funeral total information system by disqualified fee imposition standard in public cremation facilities through research and investigation focusing on the operational realities and an ordinance related to public cremation facilities made by each local government across the country, and then is to suggest a policy proposal to improve the drawn problem. As a result of the analysis, as a way to improve the drawn problems, this study suggests a policy proposal that prevents an illegal camouflaged move-in to reduce fee by restricting residence period in requirement of local residents inside the jurisdiction who can use public cremation facilities, raises fee of public cremation facilities of local residents inside the jurisdiction into the optimum level that is set cheaper than production cost, and unifies age norm of an object to apply adult fee in the central government about a difference of age norm of an object to apply fee of adult with the highest availability of public cremation facilities between local governments, resolving a fee difference through fee cutting of local residents outside the jurisdiction priced higher than production cost.

The history of ginseng cultivation in Orient (동양에 있어서의 인삼재배 역사)

  • Koh, Seungtae
    • Journal of Ginseng Culture
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    • v.1
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    • pp.57-66
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    • 2019
  • Ginseng has been recognized as a lifespan extending medicine which has been regarded as one of the medicines classified as top medicines, as the Boncho (medical herbs) study which is influenced by the idea of guidance's costume and food concept mainly in China is gaining its bona fide form. As the demand for ginseng has been expanded to other levels, the demand for ginseng has been increasing. Ginseng from the nature reached its supply chain limit due to its extinction and difficulty of picking, so it translated into ginseng cultivation of economy rather than harvesting in nature. After the start of ginseng cultivation, the ginseng cultivation was further enhanced by the rapid development of processing methods such as white-ginseng and red-ginseng, and the surge of consumption due to the traditional belief in ginseng drug efficacy and support of scientific research. In the Joseon Dynasty, the name Gasam (cultivated ginseng) had been created as ginseng was cultivated on farmland after the stage of SanYang (wild cultivated ginseng), the purpose of the new name Gasam is to differentiate from natural ginseng, and natural ginseng lost its firm position as the genuine ginseng as the Gasam replaced the genuine ginseng, and the natural ginseng got a new name of SanSam (wild ginseng). Because the real ginseng substance concept dissipated, and as Gasam is being called ginseng, the name Gasam was also disappeared. As a result, it was possible to grow large quantities according to the arrival of the Gasam era, and it was possible to supply the demand for ginseng, and it could become one agricultural industry. In this ginseng cultivation, in Japan where ginseng did not grow naturally, it was difficult to obtain ginseng from Joseon and faced with a shortage of ginseng at all times. Therefore, the shogun cultivated the Gasam systematically at the national level by the inside of the shogunate. However, since the natural ginseng is native to China and Korea, there is a concern about the deterioration of the quality of natural ginseng due to the incorporation of cultivated ginseng (Gasam). To protect the interests, the cultivation of ginseng was subject to control. For this reason, the lack of historical information on Gasam cultivation, which had to be started secretly, would be a natural result. In this paper, althouh not sufficient enough, the historical informations were used to summarize the history of ginseng cultivation in China, Japan and Korea.

IoT data trust techniques based on auto-encoder through IoT-linked processing (오토인코더 기반의 IoT 연계 처리를 통한 IoT 데이터 신뢰 기법)

  • Yon, Yong-Ho;Jeong, Yoon-Su
    • Journal of Digital Convergence
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    • v.19 no.11
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    • pp.351-357
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    • 2021
  • IoT devices, which are used in various ways in distributed environments, are becoming more important in data transmitted and received from IoT devices as fields of use such as medical, environment, transportation, bio, and public places are diversified. In this paper, as a method to ensure the reliability of IoT data, an autoencoder-based IoT-linked processing technique is proposed to classify and process numerous data by various important attributes. The proposed technique uses correlation indices for each IoT data so that IoT data is grouped and processed by blockchain by characteristics for IoT linkage processing based on autoencoder. The proposed technique expands and operates into a blockchain-based n-layer structure applied to the correlation index to ensure the reliability of IoT data. In addition, the proposed technique can not only select IoT data by applying weights to IoT collection data according to the correlation index of IoT data, but also reduce the cost of verifying the integrity of IoT data in real time. The proposed technique maintains the processing cost of IoT data so that IoT data can be expanded to an n-layer structure.

A Development of Tapered Metallic Microneedle Array for Bio-medical Application (생체의학에 적용 가능한 테이퍼형태의 금속성 마이코로니들 어레이의 개발)

  • Che Woo Seong;Lee Jeong-Bong;Kim Kabseog;Kim Kyunghwan;Jin Byung-Uk
    • Journal of the Microelectronics and Packaging Society
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    • v.11 no.2 s.31
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    • pp.59-66
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    • 2004
  • This paper presents a novel fabrication process for a tapered hollow metallic microneedle array using backside exposure of SU-8, and analytic solutions of critical buckling of a tapered hollow microneedle. An SU-8 meta was formed on a Pyrex glass substrate and another SU-8 layer, which was spun on top of the SU-8 mesa, was exposed through the backside of the glass substrate. An array of SU-8 tapered pillar structures. with angles in the range of $3.1^{\circ}{\sim}5^{\circ}$ was formed on top of the SU-8 mesa. Conformal electrodeposition of metal was carried out followed by a mechanical polishing using a pianarizing polymeric layer. All organic layers were then removed to create a metallic hollow microneedle array with a fluidic reservoir on the backside. Both $200{\mu}m\;and\;400{\mu}m$ tall, 10 by 10 arrays of metallic microneedles with inner diameters of the tip in the range of $33.6{\sim}101\;{\mu}m$ and wall thickness of $10{\mu}m\;-\;20{\mu}m$ were fabricated. Analytic solutions of the critical buckling of arbitrary-angled truncated cone-shaped columns are also presented. It was found that a single $400{\mu}m$ tall hollow cylindrical microneedle made of electroplated nickel with a wall thickness of $20{\mu}m$, a tapered angle of $3.08^{\circ}$ and a tip inner diameter of $33.6{\mu}m$ has a critical buckling force of 1.8 N. This analytic solution can be used for square or rectangular cross-sectioned column structures with proper modifications.

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