• 한국융합학회논문지
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• 제12권4호
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• pp.9-21
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• 2021

본 연구는 IP5국가(KR, EP, JP, US, CN)의 바이오헬스 분야 특허데이터를 기반으로 기술의 융합과 트렌드를 파악하여 해당 산업 분야의 발전 방향을 제시하는 것을 목적으로 한다. 기술융합 현황 파악을 위해 특허 동시분류분석 기반의 네트워크분석과 TF-IDF 기반의 텍스트마이닝을 주요 방법론으로 활용하였고, 분석 결과 바이오헬스 산업의 기술융합 클러스터는 크게 (A)치료용 의료기기, (B)의료데이터프로세싱, (C)생체계측용 의료기기의 세 가지 형태로 도출되었다. 또한 기술융합 결과를 토대로 한 트렌드 분석의 결과에서 우리나라는 (B)의료데이터프로세싱 분야에서 시장선도국으로 도출됨에 따라 향후 상업적 가치가 높은 특허로 시장 우위를 선점할 수 있는 가능성이 높다고 분석되었다. 특히 해당 분야는 2019년 1월 국회에서 통과된 '데이터3법'이라는 정책적 변환과 더불어, 국내 바이오헬스 기업들의 의료데이터 활용 가능성이 확대됨에 따라 해당 기술에 대한 기술융합 활성화 정책 수립과 R&D 지원 전략이 필요할 것으로 전망된다.

• BMB Reports
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• 제45권3호
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• pp.200-205
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• 2012

Enzymatic oxidation of commercially available pyrogallol was efficiently transformed to an oxidative product, purpurogallin. Purpurogallin plays an important role in inhibiting glutathione S-transferase, xanthine oxidase, catechol O-methyltransferase activities and is effective in the cell protection of several cell types. However, the anti-inflammatory functions of purpurogallin are not well studied. Here, we determined the effects of purpurogallin on lipopolysaccharide (LPS)-mediated proinflammatory responses. The results showed that purpurogallin inhibited LPS-mediated barrier hyper-permeability, monocyte adhesion and migration and such inhibitory effects were significantly correlated with the inhibitory functions of purpurogallin on LPS-mediated cell adhesion molecules (vascular cell adhesion molecules, intracellular cell adhesion molecule, E-selectin). Furthermore, LPS-mediated nuclear factor-${\kappa}B$ (NF-${\kappa}B$) and tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) releases from HUVECs were inhibited by purpurogallin. Given these results, purpurogallin showed its anti-inflammatory activities and could be a candidate as a therapeutic agent for various systemic inflammatory diseases.

• International journal of advanced smart convergence
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• 제6권2호
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• pp.51-58
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• 2017

Recently, rapid advances of Ethernet and IP technology have brought many changes in the sound industry. In addition, due to AoIP-based audio transmission technology, various problems of the acoustic system (sound quality deterioration due to long distance transmission, complicated wiring) have improved dramatically. However, when many distributed audio systems are connected with AoIP equipment, if there is a problem in the equipment, it is impossible to operate the connected system. AoIP equipment only can transmit audio signals but cannot adjust the system for acoustic environment. In this paper, AoIP equipment is to be installed with sound equipment on a one-to-one basis, so that various existing problems can be solved and adjustment of sound quality (reverberation, echo, delay and EQ) can be possible by AoIP-based OAC (On-site Audio Center) with built-in DSP function. As a result, uncompressed real-time transmission by distributed transmission/receipt module in OAC (On-site Audio Center) and high quality sound by adjustment of sound quality with built-in DSP can be acquired. It is expected that OAC based sound system will be the industry standard in ubiquitous environment.

• KSBB Journal
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• 제29권5호
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• pp.307-315
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• 2014

Recently seaweed polysaccharides have been extensively studied for alternative energy application. Because their producing cost is high and efficiency low, their industrial applications have been limited. The main component of cell wall of red algae represented by Gelidiales and Gracilariales is agar. Red-algae agar or galactan, consisting of D-galactose and 3, 6-anhydro-L-galactose, is suitable for bio-product application if hydrolyzed to monomer unit. For the hydrolysis of algae, chemical or enzymatic treatment can be used. A chemical process using a strong acid is simple and efficient, but it generates together with target sugar and toxic compounds. In an enzymatic hydrolysis process, target sugar without toxic compounds generation. The objective of this review is to summary the recent data of saccharification by chemical and enzymatic means from red seaweed for especially focused on automobile industry.

• 한국가구학회지
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• 제29권1호
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• pp.40-48
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• 2018

This study analyzes the contribution of hanok that construction in reducing greenhouse gas (GHG) emissions in Korea by calculating the carbon storage of hanoks and comparing it to different housing types in Korea. The hanok is a traditional Korean house. And it were first designed and built in the $14^{th}$ century during thd Joseon Dynasty. According to our results, the number of hanoks in 2016 was approximately 547,085 which was accounting for 7.8% of the total construction market, This study found Gyeongbuk with 95,083, Jeonnam with 88,981, Gyeongnam with 76,388 and Seoul with 43,519 hanoks. According to the GHG Inventory Report for 2016, Korea's total annual GHG emissions amounted to 650 million $tCO_2$, with the carbon stocks in hanoks amounting to 19.2 million $tCO_2$. This accounts for 2.8% of Korea's total GHG emissions and 46.1% of the carbon absorbed by forests. Our results show that hanoks store four times more carbon than light-frame-wood-houses, and 15 times more carbon than concrete-reinforced and steel-frame houses. The main factors causing the hanok industry slowdown are the high construction costs, lack of government support, and insufficient knowledge of hanok architecture. Therefore, to further increase the carbon stock of hanok, more research is needed to improve the technical use of wood and reduce construction of the hanok and prepare legal and institutional arrangements related to hanok industry.

• 환경영향평가
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• 제17권6호
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• pp.335-348
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• 2008

The purpose of this study is to classify the cities on sustainability assessment score studied in advance using cluster analysis, to present efficient management and policy direction based on analysis of sustainability index in 45 cities of all over Gyeongsangnam and Gyeongsangbuk-do. According to the results of cluster analysis, 45 cities were classed into 4 clusters by "livable-welfare city", "environmental -ecological city", "scientific-technological city", and "industrial-economic city". The livable-welfare cities must keep superior environmental sustainability, promote small and medium sized business on regional characteristic. The environmental-ecological cities have to change agriculture into future environmental industry such as ecotourism, bio-industry and landscape agriculture. The scientific-technological cities are going to need support of government scale such as income enlargement of citizen and stable job security. Finally, the industrial-economic cities must increase environmental management plants and improve quality of life through securing green spaces, maintaining public peace and applying UIS because of low quality of environment and life.

• 펄프종이기술
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• 제47권1호
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• pp.1-9
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• 2015

Wood fibers for medium density fiberboard (MDF) was used in the filler layer of the white duplex board for increasing thickness and bulk of the board. The MDF fibers were treated with ozone (3% based on dry weight of the fibers), and mixed together with OCC (old corrugated container) to form paper. Ozone-treated MDF fibers gave high bulk, high tensile strength, high internal bond and fast drainage to the furnish mixed with OCC. It was shown that there were possibilities to reduced basis weight of the filler layer without loss of thickness, stiffness, and tensile strength. Furthermore, it showed the possibility to develop a new kind of board product that has high stiffness as well as high strength properties with light basis weight by application of the ozone-treated MDF fibers.

• 생약학회지
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• 제45권1호
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• pp.23-27
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• 2014

Atopic dermatitis (AD) were caused by localized hypersensitivity reaction to an allergen. Therefore, to reduce inflammatory response of AD had been developed that natural extracts and oils with anti-inflammatory activities. This study were investigated that anti-inflammatory effects of Malva verticillata L. oil induced by LPS with RAW 264.7 cells. We measured to production of NO and expression of COX-2, iNOS, TNF-${\alpha}$ by RT-PCR. The Malva verticillata L. oil had decreased the production of NO (p<0.05) and the mRNA level of iNOS in concentration dose dependent manner. In conclusion, this study have shown here may be of help to understand the action mechanism of the anti-inflammatory and we hope that Malva verticillata L. oil used in skin diseases such as AD.

• 한국환경과학회지
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• 제19권9호
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• pp.1119-1127
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• 2010

The behavior of copper throughout the whole process of wastewater treatment plant that uses the activated sludge process to treat the wastewater of petrochemical industry that contains low concentration of copper was investigated. Total inflow rate of wastewater that flows into the aeration tank was $697\;m^3$/day with 0.369 mg/L of copper concentration, that is, total copper influx was 257.2 g/day. The ranges of copper concentrations of the influent to the aeration tank and effluent from the one were 0.315 ~ 0.398 mg/L and 0.159 ~ 0.192 mg/L, respectively. The average removal rate of copper in the aeration tank was 50.8 %. The bioconcentration factor (BCF) of copper by microbes in the aeration tank was 3,320. The accumulated removal rate of copper throughout the activated sludge process was 71.3%, showing a high removal ratio by physical and chemical reactions in addition to biosorption by microbes. The concentration of copper in the solid dehydrated by filter press ranged from 74.8 mg/kg to 77.2 mg/kg and the concentration of copper by elution test of waste was 2.690 ~ 2.920 mg/L. It was judged that the copper concentration in dehydrated solid by bioconcentration could be managed with the control of that in the influent.

• Journal of Biosystems Engineering
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• 제30권4호
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• pp.195-201
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• 2005

The output of Stirling engine is influenced by the regenerator effectiveness. The regenerator effectiveness is influenced by heat transfer and flow friction loss of the regenerator matrix. In this paper, in order to provide a basic data for the design of regenerator matrix, characteristics of heat transfer and flow friction loss were investigated by a packed method of matrix in the oscillating flow as the same condition of operation in a Stirling engine. As matrices, several kinds of combined wire screen meshes were used. The results are summarized as follows; The packed meshes with high mesh no. in the side of heater part of regenerator showed effective than the packed meshes with low mesh no. in the side of cooler part of regenerator. The temperature difference and pressure drop of the regenerator were not made by the specific surface area of wire screen meshes but by the minimum free-flow area to the total frontal area. Among the No. 150 single screen meshes, 200-60 combined meshes, the 200-150-100 combined meshes showed the highest in effectiveness.