• Title/Summary/Keyword: Bio-industry

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Thermoregulatory Responses of AM & PM with Body Fat Rate at a Hot Environment (서열환경하에서 체지방률에 따른 오전과 오후의 체온조절반응)

  • Kim, Seong-Suk;Lee, Jung-Sug;Kim, Hee-Eun
    • Fashion & Textile Research Journal
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    • v.7 no.3
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    • pp.315-320
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    • 2005
  • With regard to the fact that temperature of human body remains almost constant at $37^{\circ}C$, changes by circadian variation, this study intended to investigate the effect of circadian rhythm on physiological responses of human body according to body fat rate. Fifteen healthy adult women were recruited for this study and were measured body fat as a method of bio impedance. We organized subjects into three groups ; low body fat group(group L-less than 20% of body fat), medium body fat group(group M-20%~30% of body fat) and high body fat group(group H-more than 30% of body fat). The experiment was carried out in a climate chamber of $32^{\circ}C$, 60% RH with the repeat of 'Exercise' and 'Rest' period. Subjects participated in two experiments, one is morning experiment(called 'AM'), the other is afternoon experiment (called 'PM'). The results of this study are as follows ; As to the variation of rectal temperature, group L and M had a significant difference in the time of the day between AM and PM, but group H had almost the same rectal temperature in the two kinds of experimental time. The reason why group H had a smaller difference in the circadian rhythm of rectal temperature in this study is estimated at the Budd et al.(1991)'s results that body fat had effects on reduction in thermogenesis, radiation, mean skin temperature, and increase in insulation of the tissues. Group M had the highest mean skin temperature in the 'PM'. All the 3 groups didn't have stable values in 'AM'. But it showed more stable in 'PM' than 'AM'. Sweat rate was the highest in group H in both 'AM' and 'PM'. Group M had larger sweat rate in 'PM' than 'AM'. but in group L and H, sweat rate was almost the same in two kinds of time of the day. This result suggests that who have more or less body fat have larger difference in sweat rate between morning and afternoon than who have normal body fat.

Effects of Powdered Pine Needle (Pinus densiflora seib et Zucc.) on Serum and Liver Lipid Composition and Antioxidative Capacity in Rats Fed High Oxidized Fat (솔잎분말이 과산화지질을 급여한 흰쥐의 혈장 및 간장의 지질구성과 항산화능에 미치는 영향)

  • Lee, Eun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.6
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    • pp.926-930
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    • 2003
  • Effects of powdered pine needle (Pinus densiflora seib et Zucc) on serum and liver lipid composition and antioxidative capacity were investigated in rat fed high oxidized fat. Sixty male Sprague-Dawley rats weighing 161.25$\pm$2.51 g were blocked into four groups according to body weight and raised seven weeks with basal diet (normal group, I), basal diet and 10% oxidized fat (control group, II), basal diet, 10% oxidized fat and 2% powdered pine needle (2% powdered pine needle group, III) and basal diet, 10% oxidized fat and 3% powdered pine needle (3% powdered pine needle group, IV). Food intake, body weight gain and feed efficiency were not significantly different among oxidized fat diet groups. The level of plasma total cholesterol showed a tendency to decrease, whereas the plasma HDL-cholesterol concentration revealed a tendency to increase in pine needle groups. However plasma triglyceride level showed no significant differences in the treatment groups. Intake of the oxidized fat has increased the levels of liver cholesterol and triglyceride. The powdered pine needle showed a tendency to decrease thiobarbituric acid values in plasma and liver. The pine needle samples have also decreased the plasma GOT and GPT activities, whereas they have increased the liver glutathione peroxidase activity.

Piceatannol-Induced G1 Arrest of the Cell Cycle is Associated with Inhibition of Prostaglandin E2 Production in Human Gastric Cancer AGS Cells (Piceatannol에 의한 AGS 인체 위암세포의 G1 Arrest 및 Prostaglandin E2 생성의 억제)

  • Choi, Yung-Hyun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.41 no.7
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    • pp.907-913
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    • 2012
  • Piceatannol (trans-3,4,3',5'-tetrahydroxystilbene) is a polyphenol detected in grapes, rhubarb, and sugarcane. Although recent experimental data revealed that this compound is known to exhibit immunosuppressive and antitumorigenic activities in several cell lines, the molecular mechanisms underlying anticancer activity are poorly understood. In the present study, we investigated possible further mechanisms by which piceatannol exerts its anti-proliferative action in cultured human gastric cancer AGS cells. Piceatannol treatment resulted in the inhibition of growth and G1 arrest of the cell cycle in a concentration-dependent manner, as determined by MTT assay and flow cytometry analysis. The induction of G1 arrest by piceatannol was associated with the modulation of cyclin-dependent kinases (Cdks) and cyclins, up-regulation of the expression of Cdk inhibitor p21 (WAF1/CIP1) in both transcriptional and translational levels, and the inhibition of phosphorylation of retinoblastoma proteins and E2F1 expression. In addition, piceatannol treatment caused a progressive decrease in the expression levels of cyclooxygenase (COX)-2 without significant changes in the levels of COX-1, which was correlated with a decrease in prostaglandin $E_2$ synthesis.

The Effects of Stress Related Genes on Carcass Traits and Meat Quality in Pigs

  • Jin, H.J.;Park, B.Y.;Park, J.C.;Hwang, I.H.;Lee, S.S.;Yeon, S.H.;Kim, C.D.;Cho, C.Y.;Kim, Y.K.;Min, K.S.;Feng, S.T.;Li, Z.D.;Park, C.K.;Kim, C.I.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.2
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    • pp.280-285
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    • 2006
  • The current study was conducted to investigate the relationship between stress related gene and meat quality in pigs. A total number of 212 three-way cross bred (Landrace-$Yorkshire{\times}Duroc$) and 38 Duroc were sampled from the Korean pig industry to determine genotype frequency of porcine stress syndrome (PSS) and heat shock protein 70 kDa (HSP70) genes and their relationship with carcass traits and longissimus meat quality. Screen of HSP70 was performed by the single strand conformation polymorphism (SSCP) technique. Based on the analysis of restriction fragment length polymorphism (RFLP) in ryanodine receptor 1 (RYR1) gene, genetic disorder of PSS was related to a mutation at $18,168^{th}$ (C to T) of exon 17. There was no significant difference in ultimate meat pH and backfat thickness between HSP70 K1-AA type and -BB type in pure Duroc breed. In Landrace-$Yorkshire{\times}Duroc$ (L-$Y{\times}D$) cross bred pig, our results indicated that HSP70 derivate type in Duroc had a limited effect on backfat thickness, but L-$Y{\times}D$ type had a noticeable linkage with HSP70 K1-AA and K3-AB. This tendency was also observed in hot carcass weight where HSP70 K1-AA and K3-AB resulted in heavier weight with 86.3 kg compared to HSP70 K1-AB and K3-BB of 74.3 kg. Results imply that stress related HSP70 genotype has a potential association with backfat thickness and carcass weight.

Development of Ubiquitous Rice Intake Management Systems for Rice Processing Complex (미곡종합처리장을 위한 유비쿼터스 벼 반입관리 시스템 개발)

  • Lee, Hyo Jai;Kim, Oui Woung;Kim, Hoon;Kim, Byeong-Sam;Han, Jae-Woong;Han, Chung Su;Jung, Jae-Yoon
    • The Journal of Society for e-Business Studies
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    • v.18 no.2
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    • pp.175-189
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    • 2013
  • In this paper, an rice intake management system based on ubiquitous computing technology is introduced for rice processing complex (RPC). This system plays an important role in the quality management for rough rices in that the system provides timely and useful information of rice cultivation. The intake management system is developed by utilizing widespread ubiquitous technologies, such as smartphones, GIS and LBS, for the purpose of controling the harvest time and monitoring the quality of paddy. The information for rice production, cultivation and quality management is transmitted and stored in a centralized database via mobile networks, On the basis of these information, the harvest schedule is determined and notified to farmers though smart devices. Hence, the proposed system can help to establish trust among farmers, operators and consumers by providing systematic information based on ubiquitous computing technology.

Effect of the ethanolic extract of cactus pear (Opuntiaficus-indica) fruit on net handling stress in zebrafish (백년초 에탄올 추출물이 net handling stress를 유도한 제브라피쉬에 미치는 영향)

  • Oh, Won-Bo;Oh, Jun-Young;Kim, Dong-Hyun;Jung, Ji-Wook;Lee, Seung-Heon
    • The Korea Journal of Herbology
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    • v.30 no.1
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    • pp.43-49
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    • 2015
  • Objectives : In this study, the anti-stress effects of ethanolic extract of Opuntiaficus-indica (OF70E) were investigated. Methods : To determine the effects of OF70E on physical stress, changes in whole-body cortisol level or behavior were monitored in zebrafish. After treatment with 0.9% saline or OF70E for 6 min, all fish underwent net handling stress (NHS), which induced physical stress. And then, we conducted open field test (OFT) or sacrificed fish for collecting body fluid from whole-body. We used the cortisol enzyme-linked immunoassay kit to measure the amount of cortisol in each zebrafish sample. Results : In result, compared with normal group which were not treated by NHS, whole-body cortisol levels were significantly increased in stressed-control group. Compared with control group, pretreatment with OF70E at concentrations of 25, 50 and 100 mg/L for 6min significantly inhibited the increase of whole-body cortisol levels induced by NHS(p<0.05). To anti-stress effects of OF70E on behavior, we conducted OFT after the induction of NHS following pretreatment of OF70E. As results of OFT, compared with unstressed-normal group, distance moved was significantly decreased by induction of NHS in stressed-control group (p<0.05). OF70E-pretreatment blocked decreases of distance moved increased by NHS (p<0.05). And meandering movement, immobility and turn angle were significantly increased by NHS in stressed-control group compared with unstressed-normal group (p<0.05). OF70E-pretreatment prevented the increases of meandering movement immobility and turn angle by NHS (p<0.05). Conclusions : In conclusion these results suggest that OF70E-pretreatment may prevent stress responses.

A Study of Institutional Status of Risk Management for Radiotherapy in Foreign Country

  • Lee, Soon Sung;Shin, Dong Oh;Ji, Young Hoon;Kim, Dong Wook;An, Sohyoun;Park, Dong-Wook;Cho, Gyu Suk;Kim, Kum-Bae;Koo, Jihye;Oh, Yoon-Jin;Choi, Sang Hyoun
    • Progress in Medical Physics
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    • v.27 no.3
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    • pp.139-145
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    • 2016
  • With the development in field of industry and medicine, new machines and techniques are being launched. Moreover, the complexity of the techniques is associated to an increasing risk of incident. Especially, a small error in radiotherapy can lead to a serious patient-related incident, risk management is necessary in radiotherapy in order to reduce the risk of incident. However, in field of radiotherapy, there are no legally binding clauses for risk management and there is an absence of risk management systems at an institutional level. Therefore, we analyzed institutional status of risk management, reporting & classification systems, and risk assessment & analysis in 31 countries. For risk management and reporting systems, 65% of countries investigated had legislation or regulations; however, only 35% of countries used classification systems. It was found that 43% more countries had legislation for risk management in healthcare than those for radiotherapy; 19% more countries had reporting systems for healthcare than those for radiotherapy. For classification systems, 60% more countries had legislation, recommendation, and guidelines in the field of radiotherapy than those for healthcare. Recently, international institutes have published several reports for risk management and patient safety in radiotherapy, owing to which, countries adopting risk management for radiotherapy will gradually increase. Before adopting risk management in Korea, we should precisely understand the procedures and functions of risk management, in order to increase efficiency of risk management because classification & reporting system and risk assessment & analysis are connected organically, and institutional management is needed for high quality of risk management in Korea.

Screening of Biodegradable Function of Indigenous Ligno-degrading Mushroom Using Dyes

  • Jang, Kab-Yeul;Cho, Soo-Muk;Seok, Soon-Ja;Kong, Won-Sik;Kim, Gyu-Hyun;Sung, Jae-Mo
    • Mycobiology
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    • v.37 no.1
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    • pp.53-61
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    • 2009
  • The process of biodegradation in lingo-cellulosic materials is critically relevant to biospheric carbon. The study of this natural process has largely involved laboratory investigations, focused primarily on the biodegradation and recycling of agricultural by-products, generally using basidiomycetes species. In order to collect super white rot fungi and evaluate its ability to degrade lingo-cellulosic material, 35 fungal strains, collected from forests, humus soil, livestock manure, and dead trees, were screened for enzyme activities and their potential to decolorize the commercially used Poly-R 478 dye. In the laccase enzymatic analysis chemical test, 33 white rot fungi and 2 brown rot fungi were identified. The degradation ability of polycyclic aromatic hydrocarbons (PAHs) according to the utilized environmental conditions was higher in the mushrooms grown in dead trees and fallen leaves than in the mushrooms grown in humus soil and livestock manure. Using Poly-R 478 dye to assess the PAH-degradation activity of the identified strains, four strains, including Agrocybe pediades, were selected. The activities of laccase, MnP, and Lip of the four strains with PAH-degrading ability were highest in Pleurotus incarnates. 87 fungal strains, collected from forests, humus soil, livestock manure, and dead trees, were screened for enzyme activities and their potential to decolorize the commercially used Poly-R 478 dye on solid media. Using Poly-R 478 dye to assess the PAHdegrading activity of the identified strains, it was determined that MKACC 51632 and 52492 strains evidenced superior activity in static and shaken liquid cultures. Subsequent screening on plates containing the polymeric dye poly R-478, the decolorization of which is correlated with lignin degradation, resulted in the selection of a strain of Coriolus versicolor, MKACC52492, for further study, primarily due to its rapid growth rate and profound ability to decolorize poly R-478 on solid media. Considering our findings using Poly-R 478 dye to evaluate the PAH-degrading activity of the identified strains, Coriolus versicolor, MKACC 52492 was selected as a favorable strain. Coriolus versicolor, which was collected from Mt. Yeogi in Suwon, was studied for the production of the lignin-modifying enzymes laccase, manganese-dependent peroxidase (MnP), and lignin peroxidase (LiP).

Physiological Activities of Fresh Pleurotus eryngii Extracts (새송이버섯 추출물의 생리활성 효과)

  • Kim, Hyun-Ku;Han, Ho-Suk;Lee, Gee-Dong;Kim, Kong-Hwan
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.4
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    • pp.439-445
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    • 2005
  • Physiological activities of pileus and stipe extracts from fresh Pleurotus eryngii were examined. Electron donating ability (EDA), superoxide dismutase (SOD)-like activity, tyrosinase inhibitory effect, angiotensin converting enzyme (ACE) inhibitory activity, total polyphenol contents and nitrite scavenging ability were examined for extracts of pileus and stipe of Pleurotus eryngii extracted with water, $50\%$ and $100\%$ ethanol. Volume of the solvent used was 50 time of sample on a weight/volume basis. EDA was $88\%$ in $50\%$ ethanol extract (pileus). Also, SOD-like activity was $62.57\%$ in water extract (pileus). Tyrosinase inhibitory effects of all samples were higher than $0.1\%$ L-ascorbic acid solution. ACE inhibitory activity of water extract of pileus was found to be the highest value of $95.14\%$. In addition, total polyphenol contents were the highest in water and $50\%$ ethanol extracts of pileus $(1427.25\;mg\%,\;1426.82\;mg\%)$. Finally, nitrite scavenging ability of $50\%$ ethanol extract of pileus at pH 1.2 showed approximately $95\%$. The results will be useful for understanding the physiological activities of Pleurotus eryngii extracts.

Changes in Physicochemical Compounds with Heating Treatment of Ginseng (가열처리에 따른 인삼의 이화학적 성분변화)

  • Yoon, Sung-Ran;Lee, Myung-Hee;Park, Jung-Hyun;Lee, In-Seon;Kwon, Joong-Ho;Lee, Gee-Dong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.10
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    • pp.1572-1578
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    • 2005
  • Response surface methodology was used for monitoring changes in physicochemical properties with heating condition of ginseng which was sliced and freeze-dried. As heating temperature and time increased, soluble solid content decreased and browning color increased. Also, acidic polysaccharide and total phenolics increased with the increase in heating temperature and time. Heating condition for maximum soluble solid content was 146.05$^{\circ}C$ in heating temperature and 18.16 min in heating time. Maximum value of crude saponin content was 64.40 mg/g in 160.00$^{\circ}C$ and 20.00 min. Crude saponin content was influenced by heating time but the other properties were influenced by heating temperature.