• 제목/요약/키워드: Bio-aerosol

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지하철 객실 적용을 위한 황칠 추출물 소독제의 항균특성 및 안전성 평가 (Anti-bacterial properties and safety evaluation of disinfectant using Dendropanax morbifera (Hwangchil) extract for passenger cabin in the subway)

  • 부이칵호앙부;박재석;이영철
    • 한국입자에어로졸학회지
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    • 제18권2호
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    • pp.37-50
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    • 2022
  • Due to the syndrome coronavirus 2 (SARS-CoV-2) pandemic, the subway passenger cabin should be continuously sterilized. However, a disinfectant such as chlorine is toxic and can lead to different issues to human health. In this paper, we introduced a novel disinfectant based on natural product (Dendropanax morbifera extract). Via ultra-high performance liquid chromatography - mass spectrometer (UHPLC-MS), different compounds from Dendropanax morbifera extract showed antivirus potentials. Antimicrobial experiments confirmed that the air-disinfectant containing Dendropanax morbifera can eliminate harmful microorganisms including Gram (-), Gram (+), and yeast within 5 mins. The as-prepared air-disinfectant also showed high antivirus activity against H1N1, HRV, and EV71. Deodorization test also indicates that the as-prepared air-disinfectant can lower the harmful gas such as ammonia and trimethylamine in the atmosphere. To evaluate the potential of air-disinfectant containing Dendropanax morbifera in practical applications, different safety tests including acute oral toxicity, acute skin irritation, and eye irritation were conducted. Results showed that the as-prepared disinfectant did not negatively affect tested animals during these safety investigations.

의료용 흡입기 및 분무기의 성능 평가 연구 (Efficiency test Evaluation Method for Nebulizer & Medicinal Nonventilatory Nebulizer)

  • 김성민;정재훈;이주환;노승규
    • 대한의용생체공학회:의공학회지
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    • 제30권5호
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    • pp.438-443
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    • 2009
  • Nebulizer is designed to atomize medicinal fluid for patient with small particles(0.5-$5{\mu}m$) and also able to deliver particles from devices to the lungs when patient inhales air. Several particle size measurements are currently used to size aerosol particles. The most commonly used test is the cascade impactor method in as a standard. But, other methods for comparative particle size distribution data such as the particle size range and reproducibility are acceptable. Therefore, in this study a new test methode is suggested for nonventilatory nebulizer evaluation equipment.

건조제를 이용한 냉방의 위생효과 (The sanitizing effects of desiccant-based cooling)

  • 강경태;최미경
    • 대한설비공학회지:설비저널
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    • 제27권6호
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    • pp.541-547
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    • 1998
  • 공기 중에 존재하는 미생물(바이오에어로졸, bio-aerosol)은 많은 질병 발생의 원인이다. 의학계에서는 바이오에어로졸과 공기 매개성 질병의 전파와의 연관성이 잘 알려져 있다. 특히 결핵, 수두, 홍역, 천연두의 발병은 공기를 통한 질병 전파의 중요성을 확인시켜 준다. 그러나 IAQ(indoor air qualify)의 영향은 최근에서야 조사되었다. 보건의료기관과 연구실험실에서는 세균과 진균의 감염이 HVAC 시스템을 통해서 종종 일어난다. 유사한 IAQ연구에서는 바이오에어로졸이 빌딩증후군과 같은 빌딩과 관련된 질병(building-related illness, BRI), 감염, 중독성 증상, 민감성 질병과 1차적으로 연결되어 있음을 발견되었다.

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탄산탈수효소 모사를 이용한 이산화탄소 고정화 및 탄산칼슘 합성 (Carbonic Anhydrase Mimicry for Carbon Dioxide Fixation and Calcium Carbonate Mineralization)

  • 프라카쉬 챈드라 사후;장영남;채수천;이승우
    • 한국입자에어로졸학회지
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    • 제9권4호
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    • pp.201-208
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    • 2013
  • Copper (II) and Nickel (II) mimic complexes of enzyme carbonic anhydrase were evaluated under ambient condition for carbon dioxide capture and conversion process. The synthesized complexes were characterized by ATR-FTIR and UV-DR spectroscopy. It was found that all the complexes have biomimetic activity towards $CO_2$ using para-nitrophenyl acetate (p-NPA) hydrolysis as the model reaction. Interestingly, the proper geometry obtained by the restricted orientation of tripodal N atoms in Cu (II) complex of 2,6-bis(2-benzimidazolyl) pyridine showed the highest activity (1.14 au) compared to others. The $CO_2$ bio-mineralization to $CaCO_3$ was carried out via in-vitro crystallization approach. Results indicate that the biomimetic complexes have a role in determining $CaCO_3$ morphology. The present observations establish a qualitative insight for the design of improved small-molecule catalysts for carbon capture.

지하철 역사 내 코로나 바이러스 저감을 위한 이온풍 집진기 개발 (Development of an ionic wind dust collector towards coronavirus reduction in subway stations)

  • 신동호;김영훈;한방우
    • 한국입자에어로졸학회지
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    • 제18권1호
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    • pp.1-8
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    • 2022
  • Since 2019, the corona virus has been continuously affect human life. In particular, in the indoor space where people live, infection by airborne transmission of viruses is a problem. Among them, the spread in the subway, which is the main mode of transport for humans, can be serious. To solve this problem, our research team developed an ionic wind collector to collect and remove corona virus using an ionic wind collector and ozone. In order to apply the ionic wind collector to the subway, it must operate in two modes. Because large amounts of ozone are harmful to the human body. There is a mode that collects bio-aerosol from the air using ionic wind and a mode that inactivates viruses floating in the air by generating a large amount of ozone. As the applied voltage increased, the cleaning ability of the ionic wind collector increased, and the farther the distance between the discharge electrode and the ground plate, the higher the cleaning ability even at low current. In addition, clean air delivery rate (CADR) of an ionic wind collector was up to 5.5 m3/min. As a result of measuring the amount of ozone generated, it was confirmed that 50 ppb to 250 ppb was generated, and it was confirmed that ozone generation was controllable in the ionic wind dust collector.

Occupational Exposure during Intraperitoneal Pressurized Aerosol Chemotherapy Using Doxorubicin in a Pig Model

  • Wongeon Jung;Mijin Park;Soo Jin Park;Eun Ji Lee;Hee Seung Kim;Sun Ho Chung;Chungsik Yoon
    • Safety and Health at Work
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    • 제14권2호
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    • pp.237-242
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    • 2023
  • Background: This study evaluated occupational exposure levels of doxorubicin in healthcare workers performing rotational intraperitoneal pressurized aerosol chemotherapy (PIPAC) procedures. Methods: All samples were collected during PIPAC procedures applying doxorubicin to an experimental animal model (pigs). All procedures were applied to seven pigs, each for approximately 44 min. Surface samples (n = 51) were obtained from substances contaminating the PIPAC devices, surrounding objects, and protective equipment. Airborne samples were also collected around the operating table (n = 39). All samples were analyzed using ultra-high performance liquid chromatography-mass spectrometry. Results: Among the surface samples, doxorubicin was detected in only five samples (9.8%) that were directly exposed to antineoplastic drug aerosols in the abdominal cavity originating from PIPAC devices. The telescopes showed concentrations of 0.48-5.44 ng/cm2 and the trocar showed 0.98 ng/cm2 in the region where the spraying nozzles were inserted. The syringe line connector showed a maximum concentration of 181.07 ng/cm2, following a leakage. Contamination was not detected on the surgeons' gloves or shoes. Objects surrounding the operating table, including tables, operating lights, entrance doors, and trocar holders, were found to be uncontaminated. All air samples collected at locations where healthcare workers performed procedures were found to be uncontaminated. Conclusions: Most air and surface samples were uncontaminated or showed very low doxorubicin concentrations during PIPAC procedures. However, there remains a potential for leakage, in which case dermal exposure may occur. Safety protocols related to leakage accidents, selection of appropriate protective equipment, and the use of disposable devices are necessary to prevent occupational exposure.

실내 환경 요인이 치과위생사의 신체증상에 미치는 영향 (Effect of indoor environmental factors on the physical symptoms of dental hygienists)

  • 홍민희
    • 한국치위생학회지
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    • 제14권2호
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    • pp.197-204
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    • 2014
  • Objectives : The purpose of the study is to examine the effect of the indoor environmental factors of dental hygienists on physical symptoms. Methods : The subjects were 210 dental hygienists in dental hospitals and clinics in Seoul, Gyeonggi Province, Incheon and South Chungnam Province from May 1 to June 20, 2013. Results : There were significant differences between the presence or absence of windows in respiratory symptoms and eye symptoms. Room temperature, bad smell, and dry humidity had significant influences on physical and respiratory symptoms. Dermatological and ophthalmological symptoms were affected by dryness, smell and dusts. Dusts and bad smell also had influences on a variety of subjective symptoms. Conclusions : The indoor environments of dental hospitals and clinics affect the respiratory, dermatological, and ophthalmological symptoms because various hazardous materials are generated by the dental treatment. Therefore dental hygienists should have a correct understanding of bacteria, dusts and bio-aerosol in order to ensure the successful environmental control.

Validation of Ocean Color Algorithms in the Ulleung Basin, East/Japan Sea

  • Yoo, Sin-Jae;Park, Ji-Soo;Kim, Hyun-Cheol
    • 대한원격탐사학회지
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    • 제16권4호
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    • pp.315-325
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    • 2000
  • Observations were made to validate ocean color algorithms in the Ulleung Basin, East Sea in May 2000. Small scale and meso-scale surveys were conducted for the validation of ocean color products (nLw: normalized water-leaving radiance and chlorophyll concentration). There were discrepancies between SeaWiFS and in situ nLw showing the current aerosol models of standard SeaWiFS processing software are less than adequate (Gordon and Wang, 1994). Applying the standard SeaWiFS in-water algorithm resulted in an overestimation of chlorophyll concentration. This is because that CDOM absorption was higher than the estimated chlorophyll absorption. TSS concentration was also high. Therefore, the study region deviated from Case 1 waters. The source of these materials seems to be the entrainment of coastal water by the Tsushima Warm Current. Study of the bio-optical properties in other season is desirable.

NIOSH5040, IMPROVE_A, EUSAAR2을 이용한 탄소 분석 결과 비교 (Intercomparison of Carbonaceous Analytical Results using NIOSH5040, IMPROVE_A, EUSAAR2 Protocols)

  • 오세호;박다정;조지혜;한영지;배민석
    • 한국대기환경학회지
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    • 제34권3호
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    • pp.447-456
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    • 2018
  • Elemental carbon (EC) and organic carbon (OC) thermal/optical methods for the analysis of ambient particulate matter were used to analyze twenty-two $PM_{2.5}$ samples along collected from May 28 to June 20 of 2016 at the Anmyeon measurement site ($36.32^{\circ}N$; $126.19^{\circ}E$). The three laboratory OCEC protocols, which are the National Institute of Occupational Safety and Health (NIOSH5040), the Interagency Monitoring of Protected Visual Environments_A(IMPROVE_A), and European Supersites for Atmospheric Aerosol Research2 (EUSAAR2), were utilized for the aerosol characterization experiment as in intercomparisons between three protocols. There are excellent agreement for total carbon (i.e. sum of EC and OC), but statistically significant differences were observed in the split between the measured EC and OC. IMPROVE_A EC values were always larger than both NIOSH5040 and EUSAAR2 protocols. These methods exhibited significantly different temperature-distributions based on thermogram analysis, which is normalized to total carbon. In this study, a protocol for carbonaceous analysis is suggested for the Korean Peninsula.