• 한국산학기술학회논문지
• /
• 제3권4호
• /
• pp.233-239
• /
• 2002

21세기에 가장 시급하게 확보되어야 하는 기술은 BT(Biotechonolgy)와 NT(Nano technology)를 접목시키는 기술이다. 특히, 이들을 종합한 MEMS 에 관한 연구는 가장 광범위한 분야에서 활발하게 이루어지고 있어 그 기술적 가치가 점차 중요시되고 있다. 본 연구는 Simulation을 통하여 Bio-MEMS 기술에서 사용되는 미세Pump 내에서의 유체흐름을 Fluent 프로그램을 사용하여 알아보고자 하였다. 즉, 미세Pump 내로 유체가 흐를 경우, 유체의 압력변화나 온도변화 및 Model에 따른 유동의 흐름을 관찰하여 미세Pump 내에서의 최적의 외부조건과 최적의 Pump Model을 알아보고자 실험하였다. 유동의 흐름을 조사해 본 결과 Chamber의 유무에 따라 압력과 온도의 변화를 관찰할 수 있었다. Chamber가 있는 경우 압력의 변화가 적었고 온도의 변화 또한 적었다. 따라서 Chamber가 있는 Pump가 유체의 흐름에 영향을 적게 줌을 알 수 있었으며 이는 Chamber가 있는 Pump를 설계하는 것이 필요하다고 할 수 있다.

• 한국정밀공학회:학술대회논문집
• /
• 한국정밀공학회 2003년도 춘계학술대회 논문집
• /
• pp.223-227
• /
• 2003

A new flexible electronic packaging technology and its medical applications are presented. Conventional silicon chips and electronic modules can be considered as "mechanically rigid box." which does not bend due to external forces. This mechanically rigid characteristic prohibits its applications to wearable systems or bio-implantable devices. Using current MEMS (Microelectromechanical Systems) technology. a surface micromachined flexible polysilicon sensor array and flexible electrode array fer neural interface were fabricated. A chemical thinning technique has been developed to realize flexible silicon chip. To combine these techniques will result in a realization of truly flexible sensing modules. which are suitable for many medical applications.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2007년도 춘계학술대회B
• /
• pp.2781-2784
• /
• 2007

Early detection of a disease is important to tackle treatment issues in a better manner. Several diagnostic techniques are in use, these days; for such purpose and tremendous research is going on to develop newer and newer methods. However, more work is required to be done to develop cheap and reliable early detection techniques. Micro-fluidic chips are also playing key role to deliver new devices for better health care. The present study focuses on a review of recent developments in the interrogation of different techniques and present state-of-the-art of microfluidic sensor for better, quick, easy, rapid, early, inexpensive and portable POCT (Point of Care testing device) device for a particular study, in this case, bone disease called osteoporosis. Some simulations of the microchip are also made to enable feasibility of the development of a blood-chip-based system. The proposed device will assist in early detection of diseases in an effective and successful manner.

• 한국가시화정보학회지
• /
• 제1권1호
• /
• pp.28-33
• /
• 2003

This paper presents the visualization method in which 3-dimensional(3D) microchannel flow can be detected using a confocal scanning microscope. By soft-lithography, we fabricated various Bio-MEMS(Micro Electro-Mechanical System) devices such as a disposable microchip for a flow cytometer and a micro-mixer, which have 3D structures. Injecting aqueous fluorescent solution in the microfluidic devices, we measured the flow in a steady state by the confocal scanning microscope. At first, we explain the principle of the confocal scanning microscope. And then we show the results from 3D visualization of microscopic flow structures using the confocal scanning microscope.

• 유체기계공업학회:학술대회논문집
• /
• 유체기계공업학회 2003년도 유체기계 연구개발 발표회 논문집
• /
• pp.121-125
• /
• 2003

Micromixer plays an important role in Bio-MEMS or ${\mu}-TAS$. Mixing is generally generated by turbulence and interdiffusion of two fluids. Because of low Reynolds number(Re << 2000) in ${\mu}-channel$, it is difficult to generate turbulence, so mixing mainly depends on interdiffusion. Thus long channel distance is required to mix two different fluids. To reduce the channel length required for mixing, we propose the a new active ${\mu}-mixer$ that two fluids are effectively mixed in ${\mu}-channel$ by the ultrasonic wave which is generated by PZT. The ultrasonic wave is radiated into a chamber in the cross-section directional direction to interface with the two fluids. The two fluids are positioned one on top of the other. Mixing state is measured by the changing of color due to the reaction of NaOH and phenolphtalein.

• 기계저널
• /
• 제52권8호
• /
• pp.37-40
• /
• 2012

이 글에서는 DNA, 단백질 등과 같은 생체분자(biomolecule)뿐만 아니라 세포 수준에서의 정량적 분석(quantitative analysis)을 위한 강력한 도구로서 마이크로어레이 기반의 바이오멤스 기술에 대해 소개하고자 한다.

• 전자공학회논문지SC
• /
• 제42권1호
• /
• pp.33-37
• /
• 2005

마이크로믹서는 Bio-MEMS 혹은 μ-TAS 분야에서 중요한 역할을 수행한다. 혼합은 두 유체의 난류 상태와 상호확산에 의해 발생된다. 마이크로채널 내에서는 레이놀즈수가 작기 때문에 (Re << 2000) 난류가 발생되기 어려우므로 주로 상호확산에 의해서만 혼합된다. 따라서 두 유체가 적정하게 혼합되기 위해서는 긴 채널이 요구된다. 본 논문에서는 혼합에 소요되는 길이를 줄이기 위해서 PMN-PT에 의해 발생된 초음파에 의해 혼합되는 새로운 믹서를 제안하였다. 챔버 내에 발생된 초음파는 두 유체에 의해 생성된 경계면과 수직한 방향으로 방사된다. 사용된 두 유체는 상하방향으로 경계층을 이룬다. 혼합 상태는 NaOH와 페놀프탈렌의 반응에 따른 색상 변화론 관찰하여 측정하였다.

• 전자공학회지
• /
• 제24권10호
• /
• pp.63-72
• /
• 1997

Application of MEMS to biologic system mainly categorized into bio-electronics and micro-medical systems, Bio-electronics concerns on the biocompatible electronic device, in-vivo sensors, the sensors based on biological materials, biological materials for electronics and optics, the concepts and materials Inspired by biology and useful for electronics, the algorithm inspired by biology, artificial sense, and the biologic-inorganic hybrids. Micro-medical systems are utilited into the drug delivery systems, micro patient monitoring systems, micro prosthesis and artificial organs, cardiology related prothesis, analysis systems, and the minimal invasive surgery tools based on the m icrom achining technology.

• 센서학회지
• /
• 제17권1호
• /
• pp.75-80
• /
• 2008

In this work, we optimized a microbolometer for application of a $CO_2$ detector by using MEMS technology. We fabricated a stable thermal isolation structure by varying the lengths of supporting legs which affect bolometer performance. We could fabricate more stable thermal isolation structure for the microbolometer through the results of ANSYS simulations, and minimize the fabrication processes by using bulk micromachining to use a $CO_2$ detector. The microbolometer shows a detectivity of $2.5{\times}109$ cmHz$^{1/2}$/W at a chopper frequency of 8 Hz and a bias current of $6.25\;{\mu}A$ with a vacuum package of about $3.0{\times}10.3$ torr. Therefore, we put to conclusion that the microbolometer optimized in this experiment could be useful for the application of a $CO_2$ detector.

• Transactions on Electrical and Electronic Materials
• /
• 제17권3호
• /
• pp.150-154
• /
• 2016

Contact electrodes pose threats like inflammation, metal poisoning, and allergic reaction to the user during long term ECG procedure. Therefore, we present a novel noncontact electrocardiographic electrode designed through microelectromechanical systems (MEMS) process. The proposed ECG electrode consists of small inner and large outer circular copper plates separated by thin insulator. The inner plate enables capacitive transduction of bio-potential variations on a subject’s chest into a voltage that can be processed by a signal processing board, whereas the outer plate shields the inner plate from environmental electromagnetic noise. The electrode lead wires are also coaxially designed to prevent cables from coupling to ground or electronic devices. A prototype ECG electrode has an area of about 2.324 cm², is very flexible and does not require power to operate. The prototype ECG electrode could measure ECG at about 500 um distance from the subject’s chest.