• Title/Summary/Keyword: Bio Data

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Direct Pass-Through based GPU Virtualization for Biologic Applications (바이오 응용을 위한 직접 통로 기반의 GPU 가상화)

  • Choi, Dong Hoon;Jo, Heeseung;Lee, Myungho
    • KIPS Transactions on Software and Data Engineering
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    • v.2 no.2
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    • pp.113-118
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    • 2013
  • The current GPU virtualization techniques incur large overheads when executing application programs mainly due to the fine-grain time-sharing scheduling of the GPU among multiple Virtual Machines (VMs). Besides, the current techniques lack of portability, because they include the APIs for the GPU computations in the VM monitor. In this paper, we propose a low overhead and high performance GPU virtualization approach on a heterogeneous HPC system based on the open-source Xen. Our proposed techniques are tailored to the bio applications. In our virtualization framework, we allow a VM to solely occupy a GPU once the VM is assigned a GPU instead of relying on the time-sharing the GPU. This improves the performance of the applications and the utilization of the GPUs. Our techniques also allow a direct pass-through to the GPU by using the IOMMU virtualization features embedded in the hardware for the high portability. Experimental studies using microbiology genome analysis applications show that our proposed techniques based on the direct pass-through significantly reduce the overheads compared with the previous Domain0 based approaches. Furthermore, our approach closely matches the performance for the applications to the bare machine or rather improves the performance.

Genetic Characteristics of Acidovorax citrulli Population Causing Bacterial Fruit Blotch against Cucurbits in Korea (국내 박과 작물에서 과실썩음병을 일으키는 Acidovorax citrulli 집단의 유전적 특성)

  • Song, Jeong Young;Park, Su Yeon;Seo, Mun Won;Nam, Myeong Hyeon;Lim, Hyoun Sub;Lee, Seong-Chan;Lee, Youn Su;Kim, Hong Gi
    • Research in Plant Disease
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    • v.21 no.2
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    • pp.82-88
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    • 2015
  • Acidovorax citrulli, the causal agent of bacterial fruit blotch, has caused an economically destructive damage in cucurbits cultivation fields worldwide. To consider more effective disease management, 33 A. citrulli isolates collected from various cucurbits in Korea were analysed by multi-locus phylogeny using five conserved loci(16S rRNA, adk, gltA, glyA, pilT). Two distinct groups (KCC1 and KCC2) in the population were identified on the base of group-specific genetic variation. Out of them, the predominant group was KCC2 and both groups included isolates from melon, cucumber and watermelon. Sixty-four percent of KCC1 isolates were recovered from non-watermelon hosts and seventy-two percent of KCC2 isolates from watermelon. This study presented that there was genetic differentiation among A. citrulli population in Korea. Also, these results will be applied as a very useful data in effective disease management.

Psychophysiological Effects of Orchid and Rose Fragrances on Humans

  • Kim, Sung Min;Park, Seongyong;Hong, Jong Won;Jang, Eu Jean;Pak, Chun Ho
    • Horticultural Science & Technology
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    • v.34 no.3
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    • pp.472-487
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    • 2016
  • This study aimed to determine the effects of floral fragrances on human brain waves and moods. A total of 44 subjects participated in this experiment. Group 1 consisted of 11 male and 14 female college students with a mean age of 24.5 years (${\pm}2.23$) and Group 2 consisted of 10 males and 9 females with a mean age of 54.3 years (${\pm}2.98$). Subjects were exposed to floral fragrances of Rosa hybrida, 'Hera' (hereafter referred to as "rose"), Cymbidium faberi (hereafter referred to as "orchid"), or odorless control flowers (hereafter referred to as "control"). Experiments took place in three rooms (rose, orchid, and control). Electroencephalographs (EEGs) were recorded during exposure to the odors and the data were processed using quantitative electroencephalographic (QEEG) techniques. The changing EEG patterns were analyzed by brain mapping and compressed spectral arrays, and the subjects' preferences (hedonic evaluations) were quantified with an A1 index. Increased activation of absolute alpha waves was verified on six of the eight EEG channels, with the right frontal and left occipital lobes exhibiting no changes and the left parietal region showing the greatest activation. According to the QEEG measurements in the electrode sites over the frontal, temporal, parietal, and occipital lobes, the strongest absolute alpha waves were induced in the parietal lobes, followed by the temporal lobes, with the other lobes showing no significant changes. On brain maps, the orchid fragrance induced greater absolute alpha and absolute mid-beta activities compared with the rose and control fragrances, and the rose fragrance induced high absolute mid-beta activation. To identify emotional responses to floral fragrances, the subjects were requested to fill in a questionnaire and the resulting odor-related emotional descriptors were analyzed using semantic differential and factor analysis. Principal component analysis identified "elegant" as the first principal component describing the floral fragrance, followed by "refreshing" and "aromatic." The subjects gave orchid higher scores for "elegant" and "refreshing," while finding rose more "aromatic." Differences in hedonic evaluation revealed by the A1 index appeared in the 65-115 sec range of scent exposure time. The subjects with ages of around 50 years showed olfactory preferences throughout the entire experimental time of 160 sec, most markedly in the later time segment (115-165 sec), showing an increasing preference with increasing exposure time. We conclude that rose fragrance can improve concentration by creating an aromatic environment conducive to a concentrated and calm state of mind, and orchid fragrance can make people feel pampered and relaxed by creating an elegant and refreshing environment.

Effects of medicinal herb water extracts on expression of hepatic glucokinase, pyruvate dehydrogenase and acetyl-CoA carboxylase mRNA (한약재 물 추출물이 간세포 Glucokinase, Pyruvate Dehydrogenase, Acetyl-CoA Carboxylase mRNA 발현에 미치는 영향)

  • Kim, Hyun Sook;Kim, Tae Woo;Kim, Dae Jung;Lee, Jae Sung;Choe, Myeon
    • Journal of Nutrition and Health
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    • v.46 no.2
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    • pp.119-125
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    • 2013
  • We studied the anti-diabetic effects of medicinal herb water extracts on expression of hepatic glucokinase (GCK), pyruvate dehydrogenase (PDH), and acetyl-CoA carboxylase (ACC) mRNA. The medicinal herbs used for experiments were Cornus officinalis (CO), Paeonia suffruticosa Andrews (PSA), Discorea japonica Thunb. (DJ), Rehmannia glutinosa (RG), Lycium chinense (LC), and Pyrus pyrifolia (PP). For GCK mRNA expression, CO, RG, and LC water extracts exhibited a more effective activity than other extracts. Cells treated with RG and LC water extracts showed an increase in expression of PDH mRNA to 191% and 124%, respectively, compared to control. Expression of ACC mRNA was significantly higher in LC water extract. These data indicate that CO, RG, and LC water extracts stimulates expression of hepatic GCK, PDH, and ACC mRNA.

The Summer Growth and the Ratios of the Breadth to the Length of the Carapace of the Crab, Macrophthalmus (Mareotis) japonicus De Hann (강화산 칠게의 여름철 성장 및 갑폭과 중장의 비)

  • Kim, Hoon-Soo;Kwak, Hi-Sang;Kwon, Do-Heon
    • Animal Systematics, Evolution and Diversity
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    • no.nspc2
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    • pp.233-241
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    • 1988
  • The crab, Macrophthalmus (Mareotis ) japonicus , collected in 1983 from CHojijin tidal flat, southeastern part of Kangwha Island , Korea, was studied. Its caraace breadth, the carapace length , and body height were checked , and the measured raw data were analysed for the growth ratios by the mode subtraction method from the frequency distribution compared with the probability graphs. The growth rate of the crab rose more in summer than in fall and exceeded 10% during the same period on Chojijin tidal flat in Kangwha Island , Korea. Four size groups of the crab appeared in June, 1983 , but they were put together into only on emixed group by autumn. The rapid growth of the crab in summer in middle latitude comes from the seasonal bio-rhythm and the best conditions for food. But the physiological activities of the crab are reduced from autumn and the growth rate reaches the upper limits in many individuals on this tidal flat. The more the crabs grow, the more the breadth ratios to the carapac length become larger and the slopes of correlation curve get smaller. The measured values from the carapace breadth of the crab are more useful for morphological studies than those values from the carapace length or body height.

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Relationship Analysis of Reference Evapotranspiration and Heating Load for Water-Energy-Food Nexus in Greenhouse (물-에너지-식량 넥서스 분석을 위한 시설재배지의 기준작물증발산량과 난방 에너지 부하 관계 분석)

  • Kim, Kwihoon;Yoon, Pureun;Lee, Yoonhee;Lee, Sang-Hyun;Hur, Seung-Oh;Choi, Jin-Yong
    • Journal of The Korean Society of Agricultural Engineers
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    • v.61 no.4
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    • pp.23-32
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    • 2019
  • Increasing crop production with the same amount of resources is essential for enhancing the economy in agriculture. The first prerequisite is to understand relationships between the resources. The concept of WEF (Water-Energy-Food) nexus analysis was first introduced in 2011, which helps to interpret inter-linkages among the resources and stakeholders. The objective of this study was to analyze energy-water nexus in greenhouse cultivation by estimating reference evapotranspiration and heating load. For the estimation, this study used the physical model to simulate the inside temperature of the agricultural greenhouse using heating, solar radiation, ventilated and transferred heat losses as input variables. For estimating reference evapotranspiration and heating load, Penman-Monteith equation and seasonal heating load equation with HDH (Heating Degree-Hour) was applied. For calibration and validation of simulated inside temperature, used were hourly data observed from 2011 to 2012 in multi-span greenhouse. Results of the simulation were evaluated using $R^2$, MAE and RMSE, which showed 0.75, 2.22, 3.08 for calibration and 0.71, 2.39, 3.35 for validation respectively. When minimum setting temperature was $12^{\circ}C$ from 2013 to 2017, mean values of evapotranspiration and heating load were 687 mm/year and 2,147 GJ/year. For $18^{\circ}C$, Mean values of evapotranspiration and heating load were 707 mm/year and 5,616 GJ/year. From the estimation, the relationship between water and heat energy was estimated as 1.0~2.6 GJ/ton. Though additional calibrations with different types of greenhouses are necessary, the results of this study imply that they are applicable when evaluating resource relationship in the greenhouse cultivation complex.

Effects of Constitutional Food on Nurse's NK Cell Activity and Stress Reduction (체질푸드가 간호사의 스트레스 감소와 NK세포 활성도에 미치는 영향)

  • Park, Sun-Mi
    • The Journal of the Korea Contents Association
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    • v.19 no.3
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    • pp.500-509
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    • 2019
  • The study looked at the effect of body food on stress reduction and NK cell activity in improving natural healing for nurses, and examined whether it is effective in preventing and curing human health. The study was conducted for 30 days on 22 nurses who currently worked for more than a year at a general hospital in Gyeonggi Province. Stress measurements were conducted through pulse wave measuring instrument, and blood tests were conducted on the activity of NK cells. Treatment of collected data was performed by Paired t-testing through the Stat program SPSS 21 and providing body food suitable for the physical quality of participants after the classification of the body based on the internal diameter of the emperor and scholarship. Studies have shown that the effect on reducing the stress of body food has significant positive effects and that body food is effective for the activity of NK cells. This study has the following significance: First, the main health threat factor for modern people is the increased resistance of natural healing through body food to stress, which has the potential to prevent disease. Second, immunodeficiency in disease prevention and treatment is very important, which can increase the natural healing power of the human body by increasing the activity of NK cells through body food.

Antioxidant and α-Glucosidase Inhibition Activity of Solvent Fractions from Prunus mume Ethanol Extract (매실 순차분획물의 용매별 항산화 활성 및 α-glucosidase 억제 효과)

  • Kim, Jeong-Ho;Cho, Hyun-Dong;Won, Yeong-Seon;Park, Wool-Lim;Min, Hye-Ji;Han, Sim-Hee;Moon, Kwang-Deog;Seo, Kwon-Il
    • Journal of Life Science
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    • v.29 no.10
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    • pp.1111-1119
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    • 2019
  • Prunus mume, known as maesil in Korea, has been widely cultivated in East Asia and used as medication and food. However, because most of the previous studies concerning P. mume had been investigated its under extract state, detailed studies are still required for its extensive utilization. In this study, we evaluated the antioxidant and ${\alpha}-glucosidase$ inhibitory activities of solvent fractions of P. mume ethanol extracts. The ethyl acetate fraction showed higher DPPH radical scavenging activity, ABTS radical scavenging activity, reducing power, and hydrogen peroxide scavenging activity than other fractions. The DPPH radical scavenging activities of ethyl acetate fraction was 67.79%; ABTS radical scavenging activity was 60.03%; reducing power ($OD_{670}$) was 1.26; and hydrogen peroxide scavenging activity was 93.18% at $500{\mu}g/ml$. Also, the ethyl acetate and methanol fraction showed effective levels of ${\alpha}-glucosidase$ inhibition activity (69.25% and 72.29% at $500{\mu}g/ml$). Total polyphenol contents and total flavonoid contents of the ethyl acetate fraction were 88.28 mg/g (gallic acid equivalent) and 70.38 mg/g (quercetin equivalent), respectively. These results suggest that the physiological activities of the ethyl acetate fraction are associated with its polyphenol and flavonoid contents. Therefore, this study can be used as basic data for developing natural antioxidants and potential functional material using P. mume.

Anti-microbial Activity Effects of Ozonized Olive Oil Against Bacteria and Candida albicans (오존화 올리브 오일의 세균과 Candida alicans에 대한 항미생물 활성 효과)

  • Chung, Kyung Tae;Kim, Byoung Woo
    • Journal of Life Science
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    • v.29 no.2
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    • pp.223-230
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    • 2019
  • Ozone is a gaseous molecule able to kill microorganisms, such as yeast, fungi, bacteria, and protozoa. However, ozone gas is unstable and cannot be used easily. In order to utilize ozone properly and efficiently, plant oil can be employed. Ozone reacts with C-C double bonds of fatty acids, converting to ozonized oil. In this reaction, ozonide is produced within fatty acids and the resulting ozonized oil has various biological functions. In this study, we showed that ozonized oil has antimicrobial activity against fungi and bacteria. To test the antimicrobial activity of ozonized oil, we produced ozonized olive oil. Ozonized olive oil was applied to Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans. Antimicrobial activity was assayed using the disk diffusion method following the National Committee for Clinical Laboratory Standards. Minimal inhibitory concentrations (MIC) were 0.25 mg for S. aureus, 0.5 mg for S. epidermidis, 3.0 mg for P. aeruginosa, and 1.0 mg for E. coli. Gram positive bacteria were more susceptible than Gram negative bacteria. We compared growth inhibition zones against S. aureus and MRSA, showing that the ozonized olive oil was more effective on MRSA than S. aureus. Furthermore, the ozonized olive oil killed C. albicans within an hour. These data suggested that ozonized olive oil could be an alternative drug for MRSA infection and could be utilized as a potent antimicrobial and antifungal substance.

A Longitudinal Study on Customers' Usable Features and Needs of Activity Trackers as IoT based Devices (사물인터넷 기반 활동량측정기의 고객사용특성 및 욕구에 대한 종단연구)

  • Hong, Suk-Ki;Yoon, Sang-Chul
    • Journal of Internet Computing and Services
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    • v.20 no.1
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    • pp.17-24
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    • 2019
  • Since the information of $4^{th}$ Industrial Revolution is introduced in WEF (World Economic Forum) in 2016, IoT, AI, Big Data, 5G, Cloud Computing, 3D/4DPrinting, Robotics, Nano Technology, and Bio Engineering have been rapidly developed as business applications as well as technologies themselves. Among the diverse business applications for IoT, wearable devices are recognized as the leading application devices for final customers. This longitudinal study is compared to the results of the 1st study conducted to identify customer needs of activity trackers, and links the identified users' needs with the well-known marketing frame of marketing mix. For this longitudinal study, a survey was applied to university students in June, 2018, and ANOVA were applied for major variables on usable features. Further, potential customer needs were identified and visualized by Word Cloud Technique. According to the analysis results, different from other high tech IT devices, activity trackers have diverse and unique potential needs. The results of this longitudinal study contribute primarily to understand usable features and their changes according to product maturity. It would provide some valuable implications in dynamic manner to activity tracker designers as well as researchers in this arena.