• Title/Summary/Keyword: Beta radiation

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Study on the Mechanism of Radiation-induced MCP-1 Expression in RAW264.7 Macrophage Cells (RAW264.7 대식세포에서 방사선에 의한 MCP-1 발현 기작 연구)

  • Jin, Chang Hyun;Park, Yong Dae;Choi, Dae Seong;Jeong, Il Yun
    • Journal of Radiation Industry
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    • v.4 no.3
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    • pp.227-231
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    • 2010
  • The purpose of this study was to investigate the expression mechanism of MCP-1 in gamma-irradiated RAW 264.7 macrophage cells. MCP-1 plays an important role in attracting monocyte to injured site at the early inflammation stage. However the production mechanism of MCP-1 by gamma-irradiation in RAW 264.7 macrophage cells was almost undiscovered. We found that MCP-1 was produced in RAW 264.7 macrophage cells by irradiation with 5 Gy. And these inceases were attenuated by specific inhibitors treatment, such as $NF-{\kappa}B$, JNK, ERK, JAK2, and Pyk2. These results indicate that radiation-induced MCP-1 production is mediated by MyD88- and TRIF-dependent pathways in RAW 264.7 macrophage cells. Furthermore, gamma-irradiation induced heme oxygenase-1 (HO-1) expression in RAW 264.7 macrophage cells. However this induction level was reduced before MCP-1 and $IFN-{\beta}$ production.

Studies on the Reference Korean and Estimation of Radiation Exposure Dose - PHYSICAL STANDARD AND ESTIMATION OF INTER-EXTERNAL RADIATION EXPOSURE DOSE - (표준한국인(標準韓國人)의 최대허용(最大許容) 피폭선량(被曝線量) 설정(設定)에 관한 연구(硏究) - 체위(體位) 및 내(內).외부(外部) 피폭선량(被曝線量) 추정(推定) -)

  • Kim, Yung-J.;Lee, Kang-S.;Chun, Ki-J.;Kim, Jong-B.;Chung, Gook-H.;Kim, Sam-R.
    • Journal of Radiation Protection and Research
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    • v.7 no.1
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    • pp.1-10
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    • 1982
  • For the purpose of establishment of Reference Korean and estimation of internal and external exposure doses in the Reference Korean, we have surveyed reference values for Koreans, such as physical standards including height, weight and body surface area, food consumption rate of daily intake of radioactive substances and exposure dose from natural radiation. The results obtained are as follows: 1) The age group of the Reference Korean ranged from 20 to 30 years old in both sexes. The height, weight and surface area of the body of the Reference Korean are 167cm, 61kg and $1.67m^2$ in male and 155cm, 51kg and $1.51m^2$, respectively in female. 2) The food consumption of the Korean is 812.8g (669.6g of vegetable food and 143.2g of animal food) per capita per day. 3) Koreans are taken about 1,200 pCi of radioactive substances(${\beta}$-ray) per capita per day. 4) The external and internal radiation exposure doses of the Korean are estimated to be 127 mrem and 8 mrem per year, respectively. However, it is believed that these values will be modified upon the addition of data collection.

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In Situ Observation of Initial Rusting Process of Steel Containing Al Using Synchrotron Radiation X-Rays

  • Morimoto, J.;Yamashita, M.;Uchida, H.;Doi, T.;Kamimura, T.;Miyuki, H.;Konishi, H.;Mizuki, J.
    • Corrosion Science and Technology
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    • v.7 no.2
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    • pp.112-118
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    • 2008
  • We observed initial rusting process of steel containing Al under wet/dry cyclic condition with NaCl solution film using in situ X-ray diffraction spectroscopy at SPring-8 synchrotron radiation facility. It was found that mass fraction of iron oxides such as ${\alpha}-FeOOH$, ${\beta}-FeOOH$ and ${\gamma}-FeOOH$ varied with Al content. Some kinds of Al oxides were also found at the initial stage of corrosion. Those corrosion products might affect the corrosion process and corrosion rate of the steel.

Analysis of the Likelihood of Internal Radiation Exposure When Decommissioning a Nuclear Power Plant in Korea

  • Jiung Kim;Tae Young Kong;Seongjun Kim;Jinho Son;Changju Song;Jaeok Park;Seungho Jo;Hee Geun Kim
    • Journal of Radiation Industry
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    • v.18 no.2
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    • pp.141-145
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    • 2024
  • In Publication No. 66 of the International Commission on Radiological Protection, an activity median aerodynamic diameter (AMAD) of 5 ㎛ is considered in internal exposure dose assessment owing to inhalation of radionuclides in a workplace. However, analysis of aerosols generated during dismantling experiments, such as in the oxy-cutting of a reactor vessel conducted in Korea, revealed that the radioactive aerosols have AMAD ranging from 0.024 to 0.064 ㎛. Such extremely fine aerosols can induce internal exposure if inhaled. In particular, alpha radionuclides in aerosols can lead to significantly higher levels of radiation exposure than beta and gamma radionuclides, thus highlighting the need to establish appropriate internal exposure radiation protection programs and monitoring systems that specifically address alpha radionuclides when decommissioning nuclear power plants in Korea.

Adsorption of Nucleotides on ${\beta}$-Cyclodextrin Derivative Grafted Chitosan

  • Xiao Jian-Bo;Yu Hong-Zhu;Xu Ming;Chen Xiao-Qing
    • Macromolecular Research
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    • v.14 no.4
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    • pp.443-448
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    • 2006
  • A novel ${\beta}$-cyclodextrin derivative (CCD-C) was synthesized with chitosan and carboxymethyl-${\beta}$-cyclodextrin. Its structure was characterized by elemental analysis, infrared spectra analysis, and X-ray diffraction analysis. The adsorption properties for guanosine 5'-monophosphate, cytidine 5'-monophosphate and uridine 5'-monophosphate were studied. Experimental results demonstrated that CCD-C had higher adsorption capability for guanosine 5'-monophosphate, and that the adsorption capacity for guanosine 5'-monophosphate was 74.20mg/g. The adsorption capacity was greatly influenced by pH, time and temperature. The introduction of chitosan enhanced the adsorption ability and adsorption selectivity of ${\beta}$-cyclodextrin for guanosine 5'-monophosphate. This novel derivative of chitosan is expected to have wide applications in the separation, concentration and analysis of nucleotides in biological samples.

Radiochemical cis-trans Isomerization of ${\beta}$-Styrylnaphthalene (${\beta}$-스티릴나프탈렌의 방사화학적 시스-트란스 이성질화 반응)

  • Sang Chul Shim;George S. Hammond
    • Journal of the Korean Chemical Society
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    • v.20 no.4
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    • pp.290-294
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    • 1976
  • Radiation-induced cis-trans isomerization of ${\beta}$-styrylnaphthalene is studied by determination of G values and the radiostationary states. The results are compared with data obtained in direct and sensitized photoisomerization of the compound. Both the excited singlet and triplet states are involved in the isomerization of ${\beta}$-styrylnaphthalene in the radiolysis of benzene solution.

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The Effects of ${\gamma}-rays$ on Power Devices

  • Lho, Young-Hwan;Kim, Ki-Yup;Cho, Kyoung-Y.
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.2287-2290
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    • 2003
  • The electrical characteristics of power devices such as BJT (Bipolar Junction Transistor), and MOSFET (Metal Oxide Field Effect Transistor), etc, are altered due to impinging photon radiation and temperature in the nuclear or the space environment. In this paper, BJT and MOSFET are the two devices subjected to ${\gamma}$ radiation. In the case of BJT, the current gain (${\beta}$) and the collector to Emiter breakdown voltage ($V_{CEO}$) are the two main parameters considered. When it was subjected to ${\gamma}$ rays, the ${\beta}$ decreases as the dose level increases, whereas, $V_{CEO}$ gradually increases as the dose level increases. In the case of MOSFET, the threshold voltage is decreasing as the dose level increases. Here it has been observed the decent rate is an increasing function of the threshold voltage. The on-resistance does not change with respect to the dose. Both the devices recover back the original specification after the annealing is finished. No permanent damage has been occurred.

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Visible Project Area for Korean Child (Six Years Old) in Radiant Enclosures (한국 어린이를 위한 복사 공간에서의 투사 면적에 관한 연구)

  • 손철수;최민권
    • Journal of the Korean housing association
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    • v.11 no.4
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    • pp.77-84
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    • 2000
  • The purpose of this paper is to find a visible project area for an average six year old Korean child in radiant enclosures having standing pose. The results using this method will be necessary to find effective radiation area, effective radiation area factor, form factor, and mean radiant temperature for an average six years old Korean child consists of 3012 triangles. The methods to find visible project area of an average six years old Korean at arbitrary view point will be presented. The visible project area for Korean child is needed for evaluating thermal comfort for six years old Korean child. The biggest visible project area of an average six years old Korean is $\textrm{cm}^2$$2.061.0\textrm{cm}^2$ at the view point of alfa 0.0 degree and beta 0.0 degree, and the smallest visible real area of an average six years old Korean is $567.1\textrm{cm}^2$ at the view point of alfa 15.0 degree and beta 90.0 degree.

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Preclinicnl Trial of Radiation Synovectomy with Ho-166 (Ho-166 활액막절제술의 임상시험)

  • Lee, Jong-Doo
    • 대한핵의학회:학술대회논문집
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    • 1999.05a
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    • pp.200-204
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    • 1999
  • Rheumatoid arthritis (RA) is o chronic inflammatory disease of joints with proliferation of synovial epithelial tissue. Therapeutic approach of the RA consists of pharmacological and surgical interventions. Synovectomy is indicated in patients with progressive inflammatory signs and symptoms intractable to medical treatment including local intracavitary steroid injection. Recently, local injection of radionuclides which emit high energy beta rays are labeled with chemical compounds such as $^{90}Y,\;^{165}Dy-ferric$ hydroxide macroaggregate and have been introduced as an alternative therapeutic modality to surgical synovectomy. Holmium-166 is one of beta emitter and Ho-166-chitosan complex was developed for radiation synovectomy. Preclinical trial is on-going at our hospital using Ho-166-chitosan. The procedure and methods of preclinical trial are discussed.

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Utilization of Electron Beam-Radiated Cotton Waste for Agaric Mushroom Cultivation Bed (전자빔으로 처리한 폐면의 버섯배지효과)

  • Shon, Hyo-Jung;Chung, Sun-Young;Lee, Jong-Shin;Seo, Yung-Bum
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.41 no.3
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    • pp.71-75
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    • 2009
  • Cotton waste is usually used for cultivating agaric mushroom after outdoor fermentation for a few months. Electron beam was used to break down the polymer chaims of cotton waste for increasing low molecular weight soluble sugars, which may enhance the agaric mushroom cultivation. By increasing electron beam radiation, alpha cellulose content of the cotton waste was decreased while beta cellulose content and hot water solubles were increased. Electron beam radiation over 240 kGy on cotton waste caused significant increase of mushroom yield without lowering mushroom quality.