• Proceedings of the PSK Conference
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• 2003.10b
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• pp.121.1-121.1
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• 2003

Houttuynia cordata Thunb (HCT) is a herbal plant growing in China, Japan and Korea. According to the records of the Chinese medicine, this plant has been used as folk medicine for analgesics, beriberi, edema, hepatitis, icterus, etc. TCDD (2, 3, 7, 8 -tetrachlorodibenzo-p-dioxin), one of the notorious toxic environmental pollutants, damages various organs including liver and is regarded as an endocrine disrupter. After 7 days from TCDD (1$\mu$g/kg) injection, HCT (200 mg/kg) was administered into rats intraperitoneally for 4 weeks. (omitted)

• YAKHAK HOEJI
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• v.42 no.3
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• pp.238-242
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• 1998

For the investigation of bioactive natural products with analgesic activity, we have evaluated various extracts of Saururi Herba (Saururaceae), which has been used in traditiona l medicine for edema, beriberi, jaundice, turbid urine, carbuncle and furuncle. The diethylether extract of this plant was found to show a significant analgesic effect on writhing syndrome in mice. Using bioactivity-guided separation of the diethylether extract, analgesic constituent, (8S, 8`R, 7R, 6`R)-2'-oxo-4,5: 4',5'-bis(methylenedioxy)-${\Delta}^{1,3,5,3'}$-8.8', 7.6', 2.O.5'-neolignan(sauchinone) was isolated and structurally identified by physico-chemical properties and spectroscopic evidences. This compound has good analgesic activity with lower toxicity, as compared to other antipyretic-analgesic drug(acetaminophen).

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.4
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• pp.649-656
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• 2002

Damp Heat is a combination of Damp and Heat if conditioned internally and externally, and constitutes vital Ki as well as pathogenic Ki. Damp Heat, as vital Ki, is one of the essential factors in forming the body and preserving life activity, and on the other hand, as pathogenic Ki, it causes undear mentality, gastric discomfort with acid regurgitation, San disease(疝病), cardiac beriberi, flaccidity symtoms, muscular atonia or contracture and dark or cloudy urine. In Hyungsang Medicine, the Dam type develops Damp Heat disease mostly due to Heat, and the treatment is to promote urination by clearing Heat; on the other hand, in the Bangwang type, Damp is the major cause and the treatment is to induce sweating and eliminate Damp.

• Journal of Sasang Constitutional Medicine
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• v.14 no.1
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• pp.1-9
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• 2002

We analyzed 44 and 16 types of herbal medicines for Taeumin and Taeyangin, clinically applied in Dongyisoosebowon. In order to discover the standard of herbal classification for the Sasang constitutions, four concepts of Sasang Medicine were applied. These included 'Sadangron (theory of four groups)', 'Seungganggaehap (ascending-descending and gathering-dispersing)', 'Pyorihanyoul (exterior-interior and hot-cold)',and 'Hyungchiaekmi (fragrance, smell, bodily fluid and taste)'. According to these analyzing methods of herbal properties, we have reached the following conclusions: Herbal medicines for 'Taeumin' are characterized by opening energetics that reinforce dispersing Qi. The 'Exterior cold disease' is treated with herbs that ventilate the lungs and disperse dampness in three ways: by moistening the lungs, by releasing exterior, and by resolving dampness. The 'Interior heat disease' is treated with herbs that clear the liver and disperse heat in two ways. One by clearing liver heat through dispersing damp-heat of the small intestine and the other by opening orifices. Herbal medicines for Taeyangin are characterized by those that gather energy inward. They include herbs that treat beriberi, dystrophy of the extremities and vomiting, as well as, fish, shellfish, fruits and vegetable.

• Herbal Formula Science
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• v.19 no.1
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• pp.23-34
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• 2011

Objectives : Yiemyo-San(二妙散) is a basic oriental medicinal prescription used in basically musculoskeletal pain. Way down to posterity, Yiemyo-San has been combined with various prescriptions to treat a variety of diseases. the purpose of In this study is to investigate indications and etiology of indication using Yiemyo-San. Methodes : For prescriptions combining Yiemyo-San in Dongyeubogam(東醫寶鑑), the name of prescriptions, configuration herbs and indication were investigated and prescriptions were classified according to etiology of indication. Results : the numbers of prescriptions combining Yiemyo-San in Dongyeubogam were 45. Yiemyo-San was used frequently in musculoskeletal disease such as beriberi, amyotrophy, gout and arthritis(36%). In addition, it was applied to an internal diseases, ENT diseases and headache. it was used frequently in pathological condition due to supyeol(濕熱)(45%). Yiemyo-San was combined with various prescriptions as a primary prescription at 51% and as a secondary prescription at 49%. Conclusions : When Yiemyo-San is combined with other prescription, it may be used in various disease as well as musculoskeletal disease due to supyeol. combined with various prescriptions as a primary prescription at 51% and as a secondary prescription at 49%. Conclusions : When Yiemyo-San is combined with other prescription, it may be used in various disease as well as musculoskeletal disease due to supyeol.

• Journal of Haehwa Medicine
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• v.14 no.1
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• pp.155-165
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• 2005

I have come to conclusion as follows about Bangpungtongsungsan after literatural study. 1. Bangpungtongsungsan is the medical treatment of heat, wind and dryness. 2. Bangpungtongsungsan is used in head-wind, dizziness, both eye disease, tinnitus, both ear deafness, nasal polyp, uriticaria, sajuabi, beard and hair falling, apoplexy, paralysis of hands and feet, dull mentality, tetanus, epidemic disease characterized by swelling and redness of face, carbuncle, daepungchang, pustule, syphilis, tinea capitis and so on. 3. Bangpungtongsungsan is used in the disease of cerebral hemorrhage, hypertension, arteriosclerosis, constipation, rosacea, hemorrhoids, cutaneous disease, empyema, eye disease, diabetes, asthma, obesity, beriberi, erysipelas, baldhead, fatty heart, chronic nephritis and so on. 4. Bangpungtongsungsan fits in Taeumin who has much wetness-heat and those who have much heat or have much heat but don't give off well. And it doesn't fit in the disease of intolerance to cold and fever in the form of weakness headache, asthenia of the spleen and stomach, cold by internal disorder and so on.

• YAKHAK HOEJI
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• v.41 no.6
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• pp.704-708
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• 1997

In our search for bioactive natural products with antitumor activity, we have valuated various extracts of Saururi Herba (Saururaceae), which has been used in traditional medici ne for edema, beriberi, jaundice, turbid urine, carbuncle and furuncle. The hexane extract of the aerial part of this plant was found to show a potent cytotoxicity against several kinds of cultured human solid tumor cell lines (AGS, A549, HCT15, SKOV3, HEP-3B) in vitro. Using cytotoxicity-guided chromatographic separation of the hexane extract, cytotoxic constituent: 10-aminomethyl-3-hydroxy-4-methoxyphenanthrene-carboxylic acid lactam, was isolated and structurally identified by physico-chemical properties and spectroscopic evidences.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.17 no.3
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• pp.203-214
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• 2013

Objectives Yusanghan(類傷寒) means disease which chills and fever manifest like Cold damage(傷寒) but not Cold damage. However, study on Yussanghan is insignificant. The purpose of this study is to examine the origin and development process of Yusanghan. Methods: 1. Terms and disease related with Yusanghan was collected from books covering Cold damage of all time and analyzed. 2. The transition history was researched by analyzing collected terms. 3. Total appearance frequency of all time by collected disease was researched. Results: Yusanghan was appeared in Hwalinseo(活人書), which Ju Geong(朱肱) of the Song Dynasty wrote, for the first time and the definition and type were established. For the types of those, there are four diseases such as Phlegm-Fluid Retention(痰飮), Food Accumulation(食積), Vexation of Deficiency Type(虛煩), Beriberi(脚氣). Since then, the theory about Yusanghan had developed and the number of types had also increased until the Myung Dynasty. Conclusions: In early days, External Contraction Diseases(外感病) was not included in Yusanghan, but since the late Myung Dynasty, there were a lot of doctors who included External Contraction Diseases in Yusanghan, not in Cold damage. There are Summerheat Stroke, Wind-Dampness(風濕), and Warm Disease(溫病) etc. for included External Contraction Diseases. Because of this, the number of types of Yusanhan had significantly increased.

• Journal of Korean Medical classics
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• v.29 no.4
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• pp.17-36
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• 2016

Objectives : This paper seeks to study the provenances of 10 Symptoms of Para-cold damage from Yixuerumen, and discovers the rationality and originality of para-cold damages recognized by Li Chan. Methods : The paper looks through the books referenced by Yixuerumen to investigate the source text for Yixuerumen's Para-cold Damage chapter, and the contents of the referenced books will be compared to that of Yixuerumen. Results : The sources of the 10 symptoms of para-cold damage from Yixuerumen Chapter of Cold Damage can be traced to Leizhenghuorenshu (expectoration, indigestion, rising temperature due to lack of energy, and beriberi), Wang Zhen's Shanghanzhengzhimingtiao Xinzengxuleishanghansizheng(the infection in a boil, blood sattis, caused overexertion, and pox), and Liu Chun's Yujiweiyi's chapter on Common Cold. Here, Li Chan made his own addition of internal damage and damage of overworking. Li Chan seems to have considered para-cold damage not as a type of cold damage but as a "concept relative to the broader range of cold damage." In reflection of this understanding, Li Chan limited the number of categories to ten in accordance with the developmental trace leading from Leizhenghuorenshu to Shanghanzhengzhimingtiao. When we understand para-cold damage as a "concept relative to the narrower range of cold damage," it could be used as a mean as for "Wenbin diagnosis," but Yixuerumen's para-cold damage is only utilized for the "diagnosis of a broader concept of cold damage." Conclusions : Li Chan deserves credits for his academic rationality and originality displayed by the method he used to form para-cold damages where he used real cold damage and para-cold damage as principles, by the division of para-cold damage symptoms into ten provenances, by the creation of the concept of para-cold damage, and by his broad collection of prescription and treatment corresponding to each type.

• Korean Journal of Pharmacognosy
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• v.11 no.2
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• pp.85-94
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• 1980

In this paper, we studied what the drug name of Sang-Baik-Pi(桑白皮) Mori Cortex Radicis) is, how to collect it; and how the chief symptoms had changed in the chinese medical references and herbological literatures and formularies. Also we bibliographically analyzed in the herbological way the drugs combinated with Sang-Baik-Pi and their active principles among the prescriptions in the famous medical book; 'Dong-Ui-Bo-Gam', (東醫寶鑑) of our country. Finally, we concluded as foolow. Numerous names of botainical origin were described, but it was not recorded that San-Keun-Baik-Pi(桑根白皮) in old days is different from root bark of Morus sp. in this times. Sang-Baik-Pi has been a common designation since Ming dynasty (AD 1500). Collections of it were independent of seasons, it could effect perfectly over 10 years old. And its cork layer should be removed after collections, it was especially emphacised that root bark on ground was poisonous. The chiefly cured symptoms with Sang-Baik-Pi were constantly not different from the contents of 'Shin-Nong-Bon-Chau-Kyung'(神農本草經) in ancient times, but it has been developed since Ming dynasty. Its uses are widely extended to a surgical and dermatologic desease; rheumatis, beriberi and diabetes in this times. and its efficacies depend upon curing. Prescriptions on Sang-Baik-Pi that were prescribed in 'Dong-Ui-Bo-Gam' are there, 177 drugs combinated with it. Glycyrrhizae Radix is most frequently combinated with Sang-Baik-Pi(frequently 68%). It is proved that Armeniacae Semen, Platycodi Radix etc, in the order take strong effects on anti-tussive, anti-phlogistic, diuretic, anti-pyretic etc. It is expressed 34 times, frequently, that a dose is 3.75g, and it shows that a usual doses is 2-4g. As the above prescriptions are classified, the results is as follows, respiratory tract desease is most frequently in 69 prescriptions, the next gastrointestinal tract 13 times, diuretic 12 times, and antipyretic 11 times. Therefore, Sang-Baik-Pi contains a good remedial value chiefly of the effects upon the respiratory diseases.