• Molecules and Cells
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• v.20 no.3
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• pp.305-314
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• 2005

Investigation of chemically synthesized inositol 1,4,5-trisphosphate [$Ins(1,4,5)P_3$] analogs has led to the isolation of a novel binding protein with a molecular size of 130 kDa, characterized as a molecule with similar domain organization to phospholipase C-${\delta}1$ (PLC-${\delta}1$) but lacking the enzymatic activity. An isoform of the molecule was subsequently identified, and these molecules have been named PRIP (PLC-related, but catalytically inactive protein), with the two isoforms named PRIP-1 and -2. Regarding its ability to bind $Ins(1,4,5)P_3$ via the pleckstrin homology domain, the involvement of PRIP-1 in $Ins(1,4,5)P_3$-mediated $Ca^{2+}$ signaling was examined using COS-1 cells overexpressing PRIP-1 and cultured neurons prepared from PRIP-1 knock-out mice. Yeast two hybrid screening of a brain cDNA library using a unique N-terminus as bait identified GABARAP ($GABA_A$ receptor associated protein) and PP1 (protein phosphatase 1), which led us to examine the possible involvement of PRIP in $GABA_A$ receptor signaling. For this purpose PRIP knock-out mice were analyzed for $GABA_A$ receptor function in relation to the action of benzodiazepines from the electrophysiological and behavioral aspects. During the course of these experiments we found that PRIP also binds to the b-subunit of $GABA_A$ receptors and PP2A (protein phosphtase 2A). Here, we summarize how PRIP is involved in $Ins(1,4,5)P_3$-mediated $Ca^{2+}$ signaling and $GABA_A$ receptor signaling based on the characteristics of binding molecules.

• Journal of Distribution Science
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• v.16 no.8
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• pp.79-89
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• 2018

Purpose - This research aims to investigate the factors that influence consumer's overseas online shopping behavior. Consumers adopt overseas online shopping as a new buying way and more and more consumers prefer overseas online shopping than traditional shopping ways. Consumers' behaviors in this shopping experience can be different from other shopping experiences. With the increase of overseas online shopping, we need to find antecedents and results of overseas online shopping. Especially there would be positive or negative factors which influence overseas online shopping motivation. To find the relationship, this study examines self-efficacy and impulsivity as major factors which influence overseas online shopping. We also suggest that several attitude factors increase self-efficacy and it is positively related to customer satisfaction. On the other hand, we assume that overseas online shopping factors influence impulsivity of buying and it will decrease customer satisfaction. Research design, data, and methodology - This empirical study data were collected from Korean people who experience overseas online shopping. The subjects for this study were confined to shoppers who used overseas online shopping within the past six months. A total of 267 responses were gathered. SPSS 23.0, PLS 2.0 software were used in the data analysis. Descriptive statistics were used to show sample characteristics. We examined reliability, validity test for constructs. All measurement items used seven-point scales(1= very strong disagree, 7 = very strongly agree) drawn from previously published papers. Partial Least Square method was applied to find the relationship between antecedent factors and dependent factors and hypotheses were estimated. Results - Results show that perceived superiority, perceived ease of use, perceived transaction safety, perceived behavioral control positively affect self-efficacy. Self-efficacy influences positively to consumer's post purchase satisfaction. Perceived monetary benefit and perceived uniqueness motivated impulse buying. This can make consumer's post purchase dissatisfaction. Conclusions - This paper attempted to confirm the existence of both the positive and negative faces of overseas online shopping. The result reveals that self-efficacy is a major factor which may increase satisfaction in the overseas online shopping. Usually, we can think monetary benefit and uniqueness of products motivate overseas online shopping. But it can also intrigue impulse buying and negatively affect customer relationship. Therefore companies should provide enough products information to their potential customers and they might apply adequate processes such as recommendation, comparing systems to build long term relationship with their customers.

• Journal of Convergence for Information Technology
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• v.10 no.11
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• pp.340-350
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• 2020

This study was conducted to present comprehensive professionalism measurement tools suitable for hospital administration staffs. The study used measurement tools related to the psychological and behavioral characteristics of individuals used in prior studies for administration staffs at general hospitals and hospitals. Factor analysis and reliability analysis were conducted to verify the validity and internal relevance. As a result of the analysis, it was concluded that composed of 5 factors, and that the total reliability was 94.4%, which was very reasonable as a comprehensive professionalism measurement tool. Therefore, each component was defined as Confidence of Job performance, Salary Adequacy, Pride in Duties, Ability to achieve work goals, and Work Autonomy in order to provide a clear meaning. Professionalism from a modern perspective is a broader concept than traditional professionalism, including the subjective perceptions of job values and individuals' their abilities. Therefore, comprehensive professionalism measurement tools presented in this study will be very suitable and useful for hospital administration staffs.

• Journal of National Security and Military Science
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• s.5
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• pp.241-280
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• 2007

This study examines the relationship of the industry-specific factors that effect innovation of manufacturing technology and the market share within the defense industry. Since the establishment of the basic defense industry framework in 1973, there were numerous interactions of the industry-specific factors of the defense industry structure with the technological innovation and market organization of the defense industry. During last three decades, the domestic defense industry has achieved the considerable level but the framework of the basic system has not developed much in areas of the military science and the defense manufacturing technology. Industry-specific factors were formed in the process and appeared in a variety of behavioral characteristics as subsystems. Currently, there IS a growing trend where the management of defense industry is gradually deteriorating due to limitation of the domestic industry-specific factor (e.g. defense technologies, amount of demand, etc.). If there is a prominent imbalance of the industry-specific factors. it can trigger the potential problem of conflict, lack of cooperation and control, slowing the growth of the manufacturing technology thereby diminishing the market and deteriorating the defense supply/demand relationship. In a research conducted by Joe S. Bain, Bain analyzed the relationship of the traditional industrial organization where industry-specific factor(S) not only impacts the conductor(C). And, conductor(C) influences the shaping of the performance(P) of relationship of the traditional industrial organization. Consequently, the researcher has identified the demand monopoly, barriers to entry, and market competition with comparison of defense industry issues. These defense issues were three industry-specific factors identified, which are 1) The demand monopoly and The entry barriers to new market competition, 2) the industrial technical factor to a production technical competitiveness and a market sharing competitiveness, 3) the probability factor to revolution for military affairs(RMA) and a R&D production. According to baseline with these factors, the following research model is established from the special companies group(Group A), the systematization companies group(Group B), and the general companies group(Group 0. The hypothesis is that if there are more industry-specific factors, then there will be more relationships of defense industry relation statutes. This research is an empirical study on the relationship that the industry specific factors effects the innovation of manufacturing technology and the shaping of the market in the defense industry. Moreover, the existing models to evaluate the industry specific factors of the defense industry IS much to be desired with the controlled statistical analysis of the result. It is vital to study on current situation with suggesting alternative strategy to the efficient strategy. The descriptive analysis approach analysis is conducted with SPSSWIN to conduct reliability test, factor analysis, correlation analysis, cross-tabulation analysis, one-way ANOVA, and multiple regression analysis. However, there were some limitations of the survey such as the rigidity of concept about the technical factors and various market management factors. The wishes is that the decision-maker could be utilized these defence industrial factors to formulate efficient defence policy and strategy in the future.

• Journal of the Korean earth science society
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• v.23 no.4
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• pp.324-333
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• 2002

Recent studies have indicated that boys show better scientific achievements compared to those of girls. It is also a general conception that boys would be better than girls in terms of scientific creative performances and potential, although there have been few studies to support the general opinion. As the gifted education in Korea is progressing very rapidly, the importance of understanding the creative characteristics of gifted boys and girls has been increased. In the present study, we have compared and analyzed three different measures of creativity utilizing 135 gifted students (77 boys and 58 girls) to provide an empirical evidence for the different degrees of creative performances between gifted boys and girls. The instruments used to measure diverse aspects of creativity include the Torrance Test of Creativity (TTCT), the Test of Creative Problem-solving and Finding in Science (CPFS), and the Creative Behavioral Checklist in Science(CBCS). The results of the study indicate that girls, rather than boys, showed better creative performances, demonstrating moderately higher average scores on the three creative measures used in the study. The results are in contrast to people's general conception that boys would be more creative than girls. Implications of the study in connection with identification and educational practices for gifted education program have been discussed.

• Journal of Radiation Protection and Research
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• v.27 no.3
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• pp.189-198
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• 2002

The time for evacuation of residents in emergency planning zone(EPZ) of Uljin nuclear site in case of a radiological emergency was estimated with traffic analysis. Evacuees were classified into 4 groups by considering population density, local jurisdictions, and whether they ate residents or transients. The survey to investigate the behavioral characteristics of the residents was made for 200 households and included a hypothetical scenario explaining the accident situation and questions such as dwelling place, time demand for evacuation preparation transportation means for evacuation, sheltering place, and evacuation direction. The microscopic traffic simulation model, CORSIM, was used to simulate the behavior of evacuating vehicles on networks. The results showed that the evacuation time required for total vehicles to move out from EPZ took longer in the daytime than at night in spite that the delay times at intersections were longer at night than in the daytime. This was analyzed due to the differences of the trip generation time distribution. To validate whether the CORSIM model fan appropriately simulate the congested traffic phenomena assumable in case of emergency, a benchmark study was conducted at an intersection without an actuated traffic signal near Uljin site during the traffic peak-time in the morning. This study indicated that the predicted output by the CORSIM model was in good agreement with the observed data. satisfying the purpose of this study.

• Korean Journal of Environment and Ecology
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• v.26 no.1
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• pp.100-112
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• 2012

Governments and related agencies have made efforts to introduce tree burials (TB) as an alternative to solve the problems involved in the traditional funeral manners. Citizens' TB selection rates are, however, still very low. It is important to understand citizens' perceptions and attitudes towards TB to make people more actively participate in TB. This study examined citizens' knowledge, behavioral belief, attitudes towards selecting TB, intentions to select TB, and their relationship with citizens' socio-demographic characteristics. A total of 320 citizens in Gwang-ju, Korea, completed the survey during May, 2011. Results showed that 65.3% of respondents were aware of TB, and many of them (47.6%) obtained information from TV/Radio. Age, education level, marital status and birth order were related with knowledge about TB. Respondents with higher age or higher education level tended to have higher knowledge rates. The married or the non-eldest sons also had higher knowledge rates. Respondents with higher age or higher education level, and the married tended to have more positive attitudes towards selecting TB and to rate 'unconventional funeral customs' high. Respondents with higher age, education level or married respondents tended to have higher intention to select TB. The knowledge level about TB was positively related with attitudes about TB selection and intention to select TB. The results were discussed and some ways to promote TB were suggested.

• Korean Journal of Environment and Ecology
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• v.30 no.5
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• pp.857-864
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• 2016

To analyze the behavioral characteristics of Korea endangered species female gorals (n=6) during the period of birth, using GPS collar attached on their necks, we carried out this study in two areas (Seoraksan and Woraksan National park) from March 2007 to May 2014. According to our analysis there was a change in their home range during the period of birth. The home range of females (n=6) in MCP 95% was Spring ($1.00{\pm}1.00km^2$) > Autumn ($0.66{\pm}0.30km^2$) > Summer ($0.61{\pm}0.40km^2$) > Winter ($0.50{\pm}0.10km^2$) (F=4.198, p<0.05). In the monthly analysis, their home ranges were dramatically reduced in May, June and July. It showed a statistically significant difference (F=24.261, p<0.01). These gorals showing a drastic change in home ranges were identified as gorals having offspring individual and their home ranges were decreased. The average altitude was $615.77{\pm}173.508m$ and there was no significant difference in major change between parous and nonparous female gorals. Through this analysis, we expect that it can be applied to the goral management and restoration project considering the time of birth.

• Journal of the Korean Chemical Society
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• v.57 no.1
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• pp.138-146
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• 2013

This study examined the characteristics of the National Assessment of Educational Achievement (NAEA) in Science according to gender. It investigated gender achievement differences in the science section of the 2010 NAEA, the ratio of gender difference in achievement, the ratio of correct answers within each content domain and behavioral domain, and the items which showed high differences between males and females. The results indicate first, that, for 9th graders, females outperformed males in academic achievement in science. Second, with respect to the ratio of correct answers, males outperformed females in the advanced and below basic level groups, but females outperformed males in intermediate level groups. Third, females outperformed males in knowledge and inquiry in the behavior domains, and in chemistry and biology in the content domains. Fourth, an analysis of the items showing the largest gender gap indicated that males outperformed females in interpreting data, while females outperformed males in the items concerned with daily life and items related to the memorization of rules. This research on gender differences in science will allow teachers to complement the weaknesses of students when they study science, and support improved instructional methods in science.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.6
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• pp.359-366
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• 2019

Experimental and analytical studies on the behavioral characteristics of a pre-stressed (PS) steel girder are conducted to investigate the effects of deviators on the non-linear inelastic properties of the PS system. In this regard, 4 test specimens consisting of a steel H-beam, a straight cable with eccentricity, anchorages, and deviators are built and failure tests are performed under two-point loading. In addition, in-plane elastic deformation theories for the PS system without a deviator, and with three deviators at regular intervals are analytically formulated and solved using a symbolic calculation technique. To verify the validity of the experimental and the proposed analytical theories, the results obtained using FEM models composed of beam elements, rigid beam elements, and truss cable elements, are compared to the experimental results and the analytical solutions. As a result, it is determined that externally installed un-bonded deviators inhibit flexural deformation of the deformed beam to such an extent that their elastic stiffness, and failure strength are significantly improved compared to those of the PS system without deviators.