• 한국임상수의학회지
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• 제26권5호
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• pp.476-479
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• 2009

Enucleation of a 9-year-old, spayed female Pekingese's right eye was scheduled because of recurrent eyeball rupture caused by chronic corneal ulcer and descemetocele. Scoliosis of the thoracic vertebra was observed on thoracic radiography. Complete blood count, electrolytes, serum chemistry profiles were within normal ranges except of alkaline phosphatase, which was markedly improved, compared with that of five months ago. Severe respiratory sinus arrhythmia was observed before induction of anesthesia, it disappeared after induction. Retrobulbar block was performed with 0.5% bupivacaine, 2% lidocaine, 0.1% epinephrine combination (4 : 1 : 0.2 ratio of volume) before start of surgery. After retrobulbar block, heart rate decreased from 110 to 76 beats/min and sinus arrhythmia recurred. It was considered as oculocardiac reflex caused by increase of intraorbital pressure from retrobulbar block, atropine (0.025 mg/kg, IV) was administered and intermittent positive pressure ventilation was started. Three minutes after atropine administration, abnormal waveform of the electrocardiograph was appeared, it suspected as ventricular or supraventricular tachycardia, so lidocaine (2 mg/kg, IV) was administered. Then, heart rate was maintained around 130 beats/min, and the surgery was finished without the other problems. Although, retrobulbar block is performed to provide analgesia and to prevent oculocardiac reflex in ophthalmic surgery, occasionally it could induce oculocardiac reflex by infiltrated volume.

• 한국음향학회지
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• 제34권4호
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• pp.328-334
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• 2015

본 논문은 다양한 타격 강도와 위치에 따른 징의 음향 차이를 소프닝과 맥놀이 분석을 통해 살펴본다. 타격 강도는 아주 강하게, 강하게, 약하게로 구분하였고 타격 위치는 가운데, 위, 오른쪽으로 구분하였으며 분석에는 스펙트로그램을 사용하였다. 소프닝은 징의 가운데를 강하게 타격할수록 명확하게 관측되었고 주파수 이동 폭은 타격 강도와 주파수에 비례하였다. 이러한 현상은 배음에서 두드러졌으며 다른 부분음에서는 불규칙적으로 발생하였다. 맥놀이는 초기 맥놀이와 후기 맥놀이로 분류할 수 있었으며 가운데를 타격할 때보다 측면을 타격할 때 더 넓은 주파수 대역에서 더 많은 맥놀이가 발생한다는 것을 알 수 있었다. 또한 가운데를 타격한 경우 초기 맥놀이에 영향을 주는 배음 주변의 성분들이 있음을 밝혔다.

• 대한의용생체공학회:의공학회지
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• 제17권4호
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• pp.449-458
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• 1996

Most of the conventional electrocardiowaphs foil to detect signals other than P-QRS-T due to the limited SNR and bandwidth. High-resolution electrocardiography(HRECG) provides better SNR and wider bandwidth for the detection of micro-potentials with higher frequency components such as vontricular late potentials(LP). We have developed a HRECG using uncorrected XYZ lead for the detection of LPs. The overall gain of the amplifier is 4000 and the bandwidth is 0.5-300Hz without using 60Hz notch filter. Three 16-bit A/D converters sample X, Y, and Z signals simultaneously with a sampling frequency of 2000Hz. Sampled data are transmitted to a PC via a DMA-controlled, optically-coupled serial communication channel. In order to further reduce the noise, we implemented a signal averaging algorithm that averaged many instances of aligned beats. The beat alignment was carried out through the use of a template matching technique that finds a location maximizing cross-correlation with a given beat tem- plate. Beat alignment error was reduced to $\pm$0.25ms. FIR high-pass filter with cut-off frequency of 40Hz was applied to remove the low frequency components of the averaged X, Y, and Z signals. QRS onset and end point were determined from the vector magnitude of the sigrlaIL and some parameters needed to detect the existence of LP were estimated. The entire system was designed for the easy application of the future research topics including the optimal lead system, filter design, new parameter extraction, etc. In the developed HRECG, without signal averaging, the noise level was less than 5$\mu$V$_rms RTI$. With signal averaging of at least 100 beats, the noise level was reduced to 0.5$\mu$V$_rms RTI$, which is low enough to detect LPs. The developed HRECG will provide a new advanced functionality to interpretive ECG analyzers.

• 한국항공우주학회지
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• 제50권11호
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• pp.783-789
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• 2022

최근 연구에 의하면 하이브리드 로켓의 후연소실로 유입되는 연소유동은 고주파수 와류흘림을 포함하고 있으며, 노즐 벽면과 충돌하여 대향류가 형성되며 점화지연을 동반한 추가적인 연소가 발생하는 것이 확인되었다. 본 연구는 대향류 발생에 의한 점화지연이 연소압력 맥놀이가 나타나는 원인임을 확인하려 한다. 이를 위하여 Culick이 제안한 기존의 열음향 불안정 발생에 대한 에너지 킥 모델에 점화지연 발생을 반영한 수정 모델을 제안하였고 수치계산을 통하여 점화지연의 크기 변화가 열음향 결합에 의한 연소압력 맥놀이 발생을 결정하는 중요한 인자임을 확인하였다. 또한 후연소실 길이가 증가함에 따라 실험에서 관찰된 점화지연 감소는 에너지 킥과 압력의 위상 차의 증가를 가져와 맥놀이현상인 주기적인 압력증폭이 전혀 나타나지 않는 것도 확인하였다.

• Journal of Web Engineering
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• 제14권9호
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• pp.1822-1832
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• 2022

We explored the physiological effects of inhaling basil essential oil (BEO) and/or linalool and identified odor-active aroma compounds in BEO using gas chromatography/mass spectrometry (GC-MS) and GC-olfactometry (GC-O). Linalool was identified as the major volatile compound in BEO. Three groups of rats were administered BEO and linalool via inhalation, while rats in the control group were not. Inhalation of BEO for 20 min only reduced the total weight gain (190.67 ± 2.52 g) and increased the forced swimming time (47.33 ± 14.84 s) compared with the control group (219.67 ± 2.08 g, 8.33 ± 5.13 s). Inhalation of BEO for 5 min (392 ± 21 beats/min) only reduced the pulse compared with the control group (420 ± 19 beats/min). Inhalation of linalool only reduced the weight of white adipose tissue (5.75 ± 0.61 g). The levels of stress-related hormones were not significantly different among the groups. The total cholesterol and triglyceride levels decreased after inhalation of BEO for 20 min (by more than -10% and -15%, respectively). Low-density lipoprotein cholesterol levels were lowered (by more than -10%) by the inhalation of BEO and linalool, regardless of the inhalation time. In particular, BEO inhalation for 20 min was associated with the lowest level of low-density lipoprotein cholesterol (53.94 ± 2.72 mg/dL). High-density lipoprotein cholesterol levels increased after inhalation of BEO (by more than +15%). The atherogenic index and cardiac risk factors were suppressed by BEO inhalation. Animals exposed to BEO and linalool had no significant differences in hepatotoxicity. These data suggest that the inhalation of BEO and linalool may ameliorate cardiovascular and lipid dysfunctions. These effects should be explored further for clinical applications.

• 대한핵의학회지
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• 제28권2호
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• pp.177-185
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• 1994

Pharmacologic coronary vasodilation in conjunction with myocardial perfusion scintigraphy has become an alternative to dynamic exercise test for the diagnosis and risk stratification of coronary artery disease, especially in patients who are unable to perform adequate exercise. Dipyridamole and adenosine have been used for pharmacologic stress testing with myocardial perfusion imaging. Adenosine is a potent coronary vasodilator with rapid onset of action, short half-life, near maximal coronary vasodilation and less serious side effects. ST segment depression has been reported in about 7-15% of patients with coronary artery disease receiving dipyridamole in conjunction with myocardial perfusion imaging. The exact cause and clinical significance are not known. In order to evaluate the relationship between adenosine-induced ST segment depression during $^{99m}Tc$-MIBI myocardial perfusion scintigraphy and the severity of coronary artery disease, we performed $^{99m}Tc$-MIBI imaging after intravenous Infusion of adenosine In 120 patients with suspected coronary artery disease. Of the 120 patients, 28 also performed coronary angiography. There were 24 patients with ST segment depression during $^{99m}Tc$-MIBI scintigraphy and 96 patients without ST segment depression. Adenosine was infused Intravenously at a dose of 0.14mg/kg per minute lot 6minutes and $^{99m}Tc$-MIBI was injected at 3 minute. We then com-pared the hemodynamic changes, side effects, scintigraphic and angiographic findings. Heart rate increased $90{\pm}19$ beats/minute in the group with ST depression compared with $80{\pm}16$ beats/minute in the group without ST depression(p<0.05). Baseline systolic blood pressure was significantly higher in the group with ST depression($152{\pm}27$ mmHg) than in the group without 57 depression($140{\pm}21$mmHg, p<0.05). Double product at baseline($10.90{\pm}2.77$ versus $9.55{\pm}2.34\;beats/minute{\times}mmHg$) and during adenosine infusion($12.72{\pm}3.89$ versus $10.83{\pm}2.98\;beats/minute{\times}mmHg$) were significantly higher in the group with ST depression(p<0.05). The incidence of anginal chest pain was also significantly higher in the group with ST depression(ST versus 29%, p<0.0001). The $^{99m}Tc$-MIBI images were abnormal in 23(96%) patients with ST segment depression and 66(69%) patients without ST segment depression(p<0.05). In patients with ST segment depression, there were more reversible perfusion defects than in patients without ST segment depression(83 versus 55%, p<0.05). The number of abnormal segments were significantly higher in the group with ST depression($3.05{\pm}2.01$ versus $1.51{\pm}1.45$, p<0.005). In patients with ST segment depression, there were more segments of reversible perfusion defects than in patients without segment depression($2.15{\pm}2.11$ versus $0.89{\pm}1.24$, p<0.05). There were no differences in the angiographic severity by vessel(p ; NS). We concluded that ST segment depression during $^{99m}Tc$-MIBI myocardial perfusion scintigraphy with Intravenous adenosine is related to the severity of coronary artery disease.

• 한국전자통신학회논문지
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• 제15권1호
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• pp.191-198
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• 2020

본 연구는 ECG 신호를 이용하여 AR/VR 장치 사용 중에 발생할 수 있는 스트레스와 심장 상태에 따른 위험 예측을 위한 실시간 분석 시스템을 개발하였다. 제안 방법에는 ECG 신호의 R-R 간격을 이용한 HRV, BPM 측정법과 선행연구를 이용하여, 2차원 공간의 대치방법을 통해 실시간 진단방법을 제안하였다. 5분단 위로 ECG 데이터를 분석하고 자율신경계 진단 결과로 도출했다.

• IEIE Transactions on Smart Processing and Computing
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• 제6권2호
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• pp.129-132
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• 2017

A conventional pulse oximeter has high power consumption; thus, its mobility is severely limited. In this paper, we discuss the drawbacks of the existing pulse oximeters and propose a new ultra-low-power pulse oximeter that supports wireless data transmission for remotely monitoring vital signs, such as peripheral capillary oxygen saturation (SpO2) and beats per minute (BPM). We could notably reduce power consumption by using a low-frequency single clock in all well-customized modules. Also, our device is publicly certified, and thus, possibly engaged in clinical trials for commercial use.

• International journal of advanced smart convergence
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• 제3권2호
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• pp.10-13
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• 2014

In oriental medicine, the pulse beats are important signals that may let us know the conditions of one's health and disease. In other words, doctors of oriental medicine can simply analyze pulse waves anywhere and anytime to treat patients without using high-priced medical appliances. However, they are largely subjective in interpreting the pulse rates and hence their reliability is far from being perfect. The current paper aims to solve this problem by using fuzzy inference rules in judging patients' health status and to develop a software kit of intelligent electronic needles.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2001년도 제14회 신호처리 합동 학술대회 논문집
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• pp.301-304
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• 2001

이 논문에서는 미국과 유럽에서 디지털 CATV 전송 방식으로 각각 채택하고 있는 Opencable 시스템과 DVB-C 시스템의 전송성능을 비교하였다. 채널 환경의 신호손상요소는 랜덤잡음과 CTB (Composite Tripple Beats) 잡음을 고려하였다. 전송성능을 비교하기 위하여 각 전송시스템에 대한 모의실험장치를 S/W적으로 구현하여, 각 잡음 값에 따른 BER(Bit Error Rate) 값을 구하였다. 동일한 조건에서 모의실험을 실시한 결과, 64-QAM 모드에서는 Opencable 방식이 우수하고, 256-QAM 모드에서는 두 가지 전송방식의 성능이 비슷하다는 결과를 얻었다.