• Journal of the Korean Geosynthetics Society
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• v.14 no.1
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• pp.33-41
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• 2015

In this study, laboratory tests (flow, unit weight, unconfined compressive strength and bleeding tests) were performed to evaluate engineering properties of treated soil to improve pipe mixing method. As result, flow and bleeding properties are proportional to the water contents. The unit weight and unconfined compressive strength is decreased as the water contents increased. Comparing equipments contact pressure with bearing capacity of the mixed soil for dozer, backhoe and belt conveyor are immediately appliable. The applicable water content range is estimated from 80% to 200% by pipe mixing method using cement. Also, The design chart is developed from the results.

• The Journal of Korean Physical Therapy
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• v.27 no.3
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• pp.169-173
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• 2015

Purpose: This study aimed to improve the asymmetrical weight-bearing ratio, by applying different repetitive sit-to-stand training methods to the paretic-side foot of hemiplegic patients, as well as to provide the necessary information for applying balance training with hemiplegic patients. Methods: The subjects were divided into two groups: a spontaneous foot group and an asymmetrical foot group. They all performed repetitive sit-to-stand training five times a week for a total of six weeks. The sit-to-standing movement was studied using standardized clinical tests. The Biodex Balance System, Time up and go test (TUG), 5 times sit-to-stand test (5XSST), and functional reach test (FRT) were used to measure the static and dynamic standing balance of the patients. Results: In the balance system measurement, the results for the overall index, ant-post index, med-lat index, fall risk index, 5XSST, and FRT after the training differed significantly between the comparison groups (p<0.05). In the evaluation of dynamic balance, the differences in TUG did not differ significantly between the comparison groups after the training (p>0.05). Conclusion: The study found that the asymmetrical group showed significant increases in static and dynamic balance in comparison to the spontaneous group after repetitive sit-to-stand training. Based on this result, it is clear that training in an asymmetrical position with the paretic foot back can increase the left-right stability limit and the anterior-posterior stability limit, thus improving balance control.

• Geomechanics and Engineering
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• v.15 no.4
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• pp.1005-1016
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• 2018

This paper presents an investigation on the properties of two types of cement kiln dust (CKD)-stabilized dredged sediments, silt and clay with a comparison to hydrated lime stabilization. Unconfined compressive strength (UCS) and California bearing ratio (CBR) tests were conducted to examine the optimal stabilizer content and classify the type of highway material. A strength development model of treated dredged sediments was performed. The influences of various stabilizer types and sediment types on UCS were interpreted with the aid of microstructural observations, including X-ray diffraction and scanning electron microscopy analysis. The results of the tests revealed that 6% of lime by dry weight can be suggested as optimal content for the improvement of clay and silt as selected materials. For CKD-stabilized sediment as soil cement subbase material, the use of 8% CKD was suggested as optimal content for clay, whereas 6% CKD was recommended for silt; the overall CBR value agreed with the UCS test. The reaction products calcium silicate hydrate and ettringite are the controlling mechanisms for the mechanical performance of CKD-stabilized sediments, whereas calcium aluminate hydrate is the control for lime-stabilized sediments. These results will contribute to the use of CKD as a sustainable and novel stabilizer for lime in highway material applications.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3907-3912
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• 2015

Purpose: To investigate the antitumor activity and mechanism of chloroquine (CQ) in combination with cisplatin (DDP) in nude mice xenografted with gastric cancer SGC7901 cells. Materials and Methods: 35 cases of gastric cancer patients with malignant ascites were enrolled and intraperitoneal cisplatin injection was performed. Ascites were collected before and 5 days after perfusion for assessment of autophagy levels in cancer cells. In addition, 24 tumor-bearing mice were randomly divided into control, DDP, CQ and CQ + DDP groups. Results: In 54.3% (19/35) of patients the treatment was therapeutically effective (OR), 5 days after peritoneal chemotherapy, 13 patients had the decreased ascites Beclin-1 mRNA levels. In 16 patients who had NR, only 2 cases had decreased Beclin-1 (P=0.001). Compared with the control group, the xenograft growth in nude mice in the DDP group was low, and the inhibition rate was 47.6%. In combination with chloroquine, the inhibition rate increased to 84.7% (P<0.01). The LC3-II/I ratio, and Beclin1 and MDR1/P-gp expression were decreased, while caspase 3 protein levels increased (P<0.05). Conclusions: Antitumor ability of cisplatin was associated with autophagy activity and chloroquine can enhance chemosensitivity to cisplatin in gastric cancer xenografts nude mice.

• Journal of Ginseng Research
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• v.16 no.1
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• pp.7-12
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• 1992

This study was carried out to investigate the effect of water extracts from 4-, 5- and 6-year old red white ginseng roots on the inhibition of lipolysis in fat cells induced by toxohormone-L which has been known as lipolytic and anorexigenic factors. Toxohormone-L was obtained by partial purification of the ascites fluid from mice which had been inoculated with sarcoma-180. Each water extract of ginseng was effective in vitro against the inhibition of lipolysis induced by the toxohormone-L at the concentrations over 10~100 $\mu\textrm{g}$/ml. At the concentration of 1,000 $\mu\textrm{g}$/ml, the inhibition ratio of lipolysis by the water extracts of 4-, 5- and 6-year old white ginseng roots were 56.3, 59.7 and 59.4%, and those of red ginseng roots were 78.6, 79.1 and 82.5%, respectively, indicating that the 6-year old red ginseng was the most effective in the inhibition of the lipolysis. The total inhibitory activity per gram of ginseng sample was higher in the 4-year and 5-year old white ginseng roots at the concentrations of 100 $\mu\textrm{g}$/ml and 1,000 $\mu\textrm{g}$/ml, respectively, while for the red ginseng it was higher in the 6-year old ginseng than other ages regardless of the reaction concentration. Only once injection of the ginseng extracts(300 mg/ml in saline solution) with 10 ${mu}ell$/g of weight to the mice bearing sarcoma-180 was not effective against the extension of their life spans. On the contrary, the life spans of the mice were rather shortened by the injection of 5-year old white ginseng and 6-year old red ginseng, as compared to that of control.

• Economic and Environmental Geology
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• v.11 no.4
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• pp.169-182
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• 1978

The Weolagsan area consists of four units; (1) Low grade meta-sediments of the upper members of Ogcheon age unknown group such as Changri (mainly black slate and phyllitic rock), Majeonri (mainly alternation of slate, limestone and chert) and Hwanggangri Formation (pebble bearing phyllitic sediments); (2) Samtaesan Formation of Chosun System of Ordovician; (3) So called meta-volcanics and (4) Weolagsan Granite and its associations which intruded above mentioned meta-sediments and meta-volcanics. This study was focused to know the Woelagsan granite and its metasomatic effects to the country rocks petrographically and petrochemically. According to the field survey, microscopic work and some chemical analysis, the granite is a "normal granite" based on the Streckeisen's classification and belongs to a mass of the Central-zone younger group in Ogcheon geosynclinal belt. The granite metasomatized the country rocks along its northern contact zone. Zone of calcareous and cherty rocks (Majeonri formation) was silicified partly and skarned locally at the contact with the granite. The chemical analysis of the zone show no difinite variations in contents of $SiO_2$ and CaO with the distance from the granite. It seems to be indicated that the silicification of this part was not so metasomatized by the granite body, but thermally affected as much as to be partially remelted in the specific parts of the formations. Meta-volcanic rock zone was slightly chloritized near contact with the granite. Limestone of Samtaesan Formation was silicified and skarned along the contact zone by the granite body. The chemical analysis of the zone show some noticiable changes in compositions of $SiO_2$ and CaO with distance from the granite boundary. It can be imagined that the silicification of this zone was metasomatically originated by Woelagsan Granite. According to chemical analysis on several trace elements, the ratio of Zn/Cr and Ni/Cr are relatively higher than that of Cu/Cr in the above mentioned silicified zones. Generally the variation of these metal elements in the zones tend to be regular with distance from the granite body.

• Journal of Korean Society of Steel Construction
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• v.28 no.4
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• pp.231-242
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• 2016

Earthquake resistance of RC column-steel beam (RCS) joints with simplified details were studied. Simplified details are necessary for large columns to improve the productivity and constructability. To strengthen the beam-column joint, the effects of transverse beams, studs, and U-cross ties were used. Four 2/3 scale interior RCS connections were tested under cyclic lateral loading. The specimens generally exhibited good deformation capacity exceeding 4.0% story drift ratio after yielding of both beam and beam-column joint. Ultimately, the specimens failed by shear mechanism of the joint panel. The test strengths were compared with the predictions of existing design methods.

• Journal of the Korean Wood Science and Technology
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• v.39 no.1
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• pp.8-14
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• 2011

Japanese larch glulam was used as structural members to develop a modern engineered wood jointing system using traditional post and beam structure. For the connections comprised of traditional joining and drift-pins, structural members are processed at a pre-cut factory. As a basic study to examine and increase the whole shear performance of portal frame, pin withdrawal test and moment resistance tests were conducted on each connection. The post and beam members with specified connectors showed good bearing performance in the wood members' joining system, column-base and beam-end. Moment rigidity was a bit better in a joint with higher slenderness ratio of drift-pin, but moment resistance performances, yield moment and maximum moment, were excellent in smaller one.

• Journal of Food Hygiene and Safety
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• v.4 no.2
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• pp.109-118
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• 1989

To find antitumor components in the cultured mycelia of Lepiota procera, the proteinpolysaccharide obtained from the mycelia was subjected to DEAE - Sephadex A-50 column chromatography and Sepharose-4B gel filtration. Of the fractions, the purified Fraction C1 was named lepiotan and examined for antitumor activity against the solid form of sarcoma 180 in ICR mice. The inhibition ratio of lepiotan was 64% at the dose of 10 mg/kg/day for 10days. The chemical analysis of lepiotan showed 60% polysaccharide and 21 % protein. The polysaccharide moiety was found to be a heteromannoglucan which consisted of 46.3% glucose, 40.2% mannose and 11.0% fucose. When the antitumor component, Fraction A, was examined for immunopotentiation activity, it was found to increase the number of plaques in hemolytic plaque assay and to restore the immunity in the tumor-bearing mice up to 89.7% of the normal level. Also the antitumor acitivity was suppressed by the treatment with carrageenan, an antimacrophage agent. These results indicate that the antitumor activity was exerted through immunopotentiation, but not through direct cytotoxicity against the tumor.

• Journal of the Korean Geotechnical Society
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• v.21 no.2
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• pp.67-84
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• 2005

This research was conducted to evaluate the effectiveness of reinforcement for nearly saturated soft clay compaction. The effectiveness was investigated by roller compaction test using nearly saturated clay specimens. The nearly saturated condition was obtained by submerging clay in the water for 12 hours. High water content specimens were compacted in plane strain condition by a steel roller. A specimen was compacted by four 5 cm horizontal layers. Specimens were prepared fur both reinforced and unreinforced cases to evaluate the effectiveness of reinforcement. Used reinforcement is a composite consisted of both woven and non-woven geotextile. The composite usually provides drainage and tensile reinforcement to hi인 water-contented clay so that it increases bearing capacity. Therefore, large compaction load can be applied to reinforced clay and it achieves higher density effectively. The reinforcement also increases compaction efficiency because it reduces the ratio between shear and vertical forces during compaction process. The maximum vertical stress on the base of specimen usually decreased with higher compaction thickness. The reinforcement increases soil stiffness under the compaction roller and it initiates stress concentration. As a result, it maintains higher vertical stress level on the base of specimen that provides better compaction characteristics. Based on test results, it can be concluded that the reinforcement is essential to achieve effective compaction on soft clay.