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Ag Ion Substituted HAp Coatings on Ti-6Al-4V Substrate by IBAD and It's Bactericidal Effect (Ti 합금표면의 항균성 HAp Coating에 관한 연구)

  • Jung, Moon-Young;Kim, Taik-Nam;Kim, Yun-Jong;Yim, Hyuk-Jun;Kim, Jong-Ock;Lim, Dae-young;Kim, Sun-Ok
    • The Journal of Engineering Research
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    • v.3 no.1
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    • pp.189-197
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    • 1998
  • Hyeroxyapatite(HAp) which has good biocompatibility was made by Wet Chemical Process. The surface of Ti-6Al-4V, coated with HAp by lon Beam Assisted Deposition (IBAD), was treated with 5ppm, 10ppm, 20ppm, and 100ppm of $AgNO_3$ solution. In this Ag impregnation process, $Ca^{2+}$ of HAp was substituted with $Ag^+$ of $AgNO_3$. In this study, the antimicrobial effect and biocompatibility of Ti-6Al-4V alloy which was coated with Ag-HAp were examined. The antimicrobial test was carried out with two kinds of bacteria(P. Aeruginosa, S. Epidermidis), which are highly infectious in a transplanting operation of implant materials. As a result of the test, it was observed that Ti-6Al-4V alloy which was treated by 20ppm of $AgNO_3$ solution has good biocompatibility. In order to observe the antimicrobial mechanism of $Ag^+$, E. coli which is the most common bacterium was treated by Ag-HAp. Then cell morphology of E. coli was observed by the transmission electron microscope(TEM). The destruction of cell wall and cytoplasm of E. coil were observed. A black spot appeared in the cytoplasm was analyzed by energy dispersive analysis X-ray (EDAX) and it showed a small amount of $Ag^+$. Thus, it was proved that $Ag^+$ destroys bacteria effectively and Ti-6Al-4V alloy which was impregnate with Ag ion show antimicrobial effect on infection bacteria.

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Analyze for the Quality Control of General X-ray Systems in Capital region (수도권지역 일반촬영 장비의 정도관리 분석)

  • Kang, Byung-Sam;Lee, Kang-Min;Shim, Woo-Yong;Park, Soon-Chul;Choi, Hak-Dong;Cho, Yong-Kwon
    • Journal of radiological science and technology
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    • v.35 no.2
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    • pp.93-102
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    • 2012
  • Thanks to the rapid increase of the interest in the quality control of the General X-ray systems, this research proposes the direction of the quality control through comparing and inspecting the actual condition of the respective quality control in the Clinic, the educational institution and the hospital. The subjects of the investigation are diagnostic radiation equipment's in the clinic, the educational institution and the hospital around the capital. A test of kVp, mR/mAs out put test and reproducibility of the exposure dose, half value layer, an accordance between the light field and the beam alignment test, and lastly reproducibility of the exposure time. Then the mean difference of the percentage, the CV (Coefficient of Variation, CV) and the attenuated curve which are respectively resulted from the above tests are computed. After that we have evaluated the values according to the regulations on the Diagnostic Radiation Equipment Safety Administration regulations. In the case of the clinic and the educational institution, there were 22 general X-ray devices. And 18.2% of the kVp test, 13.6% of the reproducibility of exposure dose test, 9.1% of the mR/mAs out put test, and 13.6% of the HVL (Half Value Layer) test appeared to be improper. In the case of the hospital, however, there were 28 devices. And 7.1% of the reproducibility of exposure dose, 7.1% of the difference in the light field/ beam alignment, and 7.1% of the reproducibility of the exposure time appeared to be improper. According to the investigation, the hospital's quality control condition is better than the condition in the clinic and the educational institution. The quality control condition of the general X-ray devices in the clinic is unsatisfactory compared to the hospital. Thus, it is considered that realizing the importance of the quality control is necessary.

A Study on Mechanical Errors in Cone Beam Computed Tomography(CBCT) System (콘빔 전산화단층촬영(CBCT) 시스템에서 기계적 오류에 관한 연구)

  • Lee, Yi-Seong;Yoo, Eun-Jeong;Kim, Seung-Keun;Choi, Kyoung-Sik;Lee, Jeong-Woo;Suh, Tae-Suk;Kim, Joeng-Koo
    • Journal of radiological science and technology
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    • v.36 no.2
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    • pp.123-129
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    • 2013
  • This study investigated the rate of setup variance by the rotating unbalance of gantry in image-guided radiation therapy. The equipments used linear accelerator(Elekta Synergy TM, UK) and a three-dimensional volume imaging mode(3D Volume View) in cone beam computed tomography(CBCT) system. 2D images obtained by rotating $360^{\circ}$and $180^{\circ}$ were reconstructed to 3D image. Catpan503 phantom and homogeneous phantom were used to measure the setup errors. Ball-bearing phantom was used to check the rotation axis of the CBCT. The volume image from CBCT using Catphan503 phantom and homogeneous phantom were analyzed and compared to images from conventional CT in the six dimensional view(X, Y, Z, Roll, Pitch, and Yaw). The variance ratio of setup error were difference in X 0.6 mm, Y 0.5 mm Z 0.5 mm when the gantry rotated $360^{\circ}$ in orthogonal coordinate. whereas rotated $180^{\circ}$, the error measured 0.9 mm, 0.2 mm, 0.3 mm in X, Y, Z respectively. In the rotating coordinates, the more increased the rotating unbalance, the more raised average ratio of setup errors. The resolution of CBCT images showed 2 level of difference in the table recommended. CBCT had a good agreement compared to each recommended values which is the mechanical safety, geometry accuracy and image quality. The rotating unbalance of gentry vary hardly in orthogonal coordinate. However, in rotating coordinate of gantry exceeded the ${\pm}1^{\circ}$ of recommended value. Therefore, when we do sophisticated radiation therapy six dimensional correction is needed.

Comparison and evaluation of treatment plans using Abdominal compression and Continuous Positive Air Pressure for lung cancer SABR (폐암의 SABR(Stereotactic Ablative Radiotherapy)시 복부압박(Abdominal compression)과 CPAP(Continuous Positive Air Pressure)를 이용한 치료계획의 비교 및 평가)

  • Kim, Dae Ho;Son, Sang Jun;Mun, Jun Ki;Park, Jang Pil;Lee, Je Hee
    • The Journal of Korean Society for Radiation Therapy
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    • v.33
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    • pp.35-46
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    • 2021
  • Purpose : By comparing and analyzing treatment plans using abdominal compression and The Continuous Positive Air Pressure(CPAP) during SABR of lung cancer, we try to contribute to the improvement of radiotherapy effect. Materials & Methods : In two of the lung SABR patients(A, B patient), we developed a SABR plan using abdominal compression device(the Body Pro-Lok, BPL) and CPAP and analyze the treatment plan through homogeneity, conformity and the parameters proposed in RTOG 0813. Furthermore, for each phase, the X, Y, and Z axis movements centered on PTV are analyzed in all 4D CTs and compared by obtaining the volume and average dose of PTV and OAR. Four cone beam computed tomography(CBCT) were used to measure the directions from the center of the PTV to the intrathoracic contacts in three directions out of 0°, 90°, 180° and 270°, and compare the differences from the average distance values in each direction. Result : Both treatment plans obtained using BPL and CPAP followed recommendations from RTOG, and there was no significant difference in homogeneity and conformity. The X-axis, Y-axis, and Z-axis movements centered on PTV in patient A were 0.49 cm, 0.37 cm, 1.66 cm with BPL and 0.16 cm, 0.12 cm, and 0.19 cm with CPAP, in patient B were 0.22 cm, 0.18 cm, 1.03 cm with BPL and 0.14 cm, 0.11 cm, and 0.4 cm with CPAP. In A patient, when using CPAP compared to BPL, ITV decreased by 46.27% and left lung volume increased by 41.94%, and average dose decreased by 52.81% in the heart. In B patient, volume increased by 106.89% in the left lung and 87.32% in the right lung, with an average dose decreased by 44.30% in the stomach. The maximum difference of A patient between the straight distance value and the mean distance value in each direction was 0.05 cm in the a-direction, 0.05 cm in the b-direction, and 0.41 cm in the c-direction. In B patient, there was a difference of 0.19 cm in the d-direction, 0.49 cm in the e-direction, and 0.06 cm in the f-direction. Conclusion : We confirm that increased lung volume with CPAP can reduce doses of OAR near the target more effectively than with BPL, and also contribute more effectively to restriction of tumor movement with respiration. It is considered that radiation therapy effects can be improved through the application of various sites of CPAP and the combination with CPAP and other treatment machines.

An Understanding the Opening Style of the West Philippine Basin Through Multibeam High-Resolution Bathymetry (고해상도 다중빔음향측심 지형자료 분석을 통한 서필리핀분지의 진화 연구)

  • Hanjin Choe;Hyeonuk Shin
    • Journal of the Korean earth science society
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    • v.44 no.6
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    • pp.643-654
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    • 2023
  • The West Philippine Basin, an oceanic basin half the size of the Philippine Sea Plate, lies in the western part of the plate and south of the Korean Peninsula on the Eurasian Plate. It subducts beneath the Eurasian Plate and the Philippine Islands bordering the Ryukyu Trench and the Philippine Trench with 25-50% of this basin already consumed. However, the history of the opening of the basin's southern region has been a topic of debate. The non-transform discontinuity formed during the seafloor spreading is similar to the transform fault boundaries normally perpendicular to mid-ocean ridge axes; however, it was created irregularly due to ridge propagations caused by variations of mantle convection attributable to magma supply changes. By analyzing high-resolution multi-beam echo-sounding data, we confirmed that the non-transform discontinuity due to the propagating rift evolved in the entire basin and that the abyssal hill strike direction changed from E-W to NNW-SSE from the fossil spreading center. In the early stage of basin extension, the Amami-Sankaku Basin was rotated 90 degrees clockwise from its current orientation, and it bordered the Palau Basin along the Mindanao Fracture Zone. The Amami-Sankaku Basin separated from the Palau Basin while the spreading of the West Philippine Basin began with a counter-clockwise rotation. This indicates that the non-transform discontinuities formed by a sudden change in magma supply due to the drift of the Philippine Sea Plate and simultaneously with the rapid changes in the spreading direction from ENE-WSW to N-S. The Palau Basin was considered to be the sub-south of the West Philippine Basin, but recent studies have shown that it extends into an independent system. Evidence from sediment layers and crustal thickness hints at the possibility of its existence before the West Philippine Basin opened, although its evolution continues to be debated. We performed a combined analysis using high-resolution multi-beam bathymetry and satellite gravity data to uncover new insights into the evolution of the West Philippine Basin. This information illuminates the complex plate interactions and provides a crucial contribution toward understanding the opening history of the basin and the Philippine Sea Plate.

Numerical Simulation for the Quasi-static Behavior of Superelastic Nitinol Shape Memory Alloys (SMAs) (초탄성 니티놀 형상기억합금의 준정적 거동에 대한 수치해석적 재현)

  • Hu, Jong Wan
    • Journal of Korean Society of Steel Construction
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    • v.27 no.6
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    • pp.493-501
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    • 2015
  • Superelastic shape memory alloys (SMAs) are metallic materials that can automatically recover to their original condition without heat treatment only after the removal of the applied load. These smart materials have been wildly applied instead of steel materials to the place where large deformation is likely to concentrate. In spite of many advantages, superelastic SMA materials have been limited to use in the construction filed because there is lack of effort and research involved with the development of the material model, which is required to reproduce the behavior of superelastic SMA materials. Therefore, constitutive material models as well as algorithm codes are mainly treated in this study for the purpose of simulating their hysteretic behavior through numerical analyses. The simulated curves are compared and calibrated to the experimental test results with an aim to verify the adequacy of material modeling. Furthermore, structural analyses incorporating the material property of the superelastic SMAs are conducted on simple and cantilever beam models. It can be shown that constitutive material models presented herein are adequate to reliably predict the behavior of superelastic SMA materials under cyclic loadings.

No asymmetric outflows from Sagittarius A* during the pericenter passage of the gas cloud G2

  • Park, Jong-Ho;Trippe, Sascha;Krichbaum, Thomas;Kim, Jae-Young;Kino, Motoki;Bertarini, Alessandra;Bremer, Michael;de Vicente, Pablo
    • The Bulletin of The Korean Astronomical Society
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    • v.40 no.1
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    • pp.73.2-74
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    • 2015
  • The gas cloud G2 falling toward Sagittarius A* (Sgr A*), the supermassive black hole at the center of the Milky Way, is supposed to provide valuable information on the physics of accretion flows and the environment of the black hole. We observed Sgr A* with four European stations of the Global Millimeter Very Long Baseline Interferometry Array (GMVA) at 86 GHz on 1 October 2013 when parts of G2 had already passed the pericenter. We searched for possible transient asymmetric structure - such as jets or winds from hot accretion flows - around Sgr A* caused by accretion of material from G2. The interferometric closure phases (which are zero if the spatial brightness distribution of the target is symmetric, and deviate from zero otherwise) remained zero within errors during the observation time. We thus conclude that Sgr A* did not show significant asymmetric (in the observer frame) outflows in late 2013. Using simulations, we constrain the size of the outflows that we could have missed to ${\approx}2.5$ mas along the major axis, ${\approx}0.4$ mas along the minor axis of the beam, corresponding to approximately 232 and 35 Schwarzschild radii, respectively; we thus probe spatial scales on which the jets of radio galaxies are suspected to convert magnetic into kinetic energy. As probably less than 0.2 Jy of the flux from Sgr A* can be attributed to accretion from G2, one finds an effective accretion rate ${\eta}M{\leq}1.5{\times}10^9kg/s{\approx}7.7{\times}10^{-9}M_{earth}/yr$ for material from G2. Exploiting the kinetic jet power-accretion power relation of radio galaxies, one finds that the rate of accretion of matter that ends up in jets is limited to $M{\leq}10^{17}kg/s{\approx}0.5M_{Earth}/yr$ less than about 20% of the mass of G2. Accordingly, G2 appears to be largely stable against loss of angular momentum and subsequent (partial) accretion at least on time scales ${\leq}1$ year.

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Anatomic Study of Pterygomaxillary Junctions in Koreans

  • Kim, Dong-Yul;Cho, Yeong-Cheol;Sung, Iel-Yong;Yun, Dae-Kawn;Kim, Min-Uk;Kim, Ji-Uk;Son, Hyung-Suck;Son, Jang-Ho
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.35 no.6
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    • pp.368-375
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    • 2013
  • Purpose: This study is to evaluate the location of descending palatine artery, the anatomy of pterygomaxillary junction, and the association between the obtained anatomic values and several variables. Methods: We studied 40 patients who were treated for dentofacial deformites from January 2010 to December 2012 in Ulsan University Hospital, Ulsan, Korea. Cone beam computed tomogram (CBCT) was done for all patients. The reference point was approximately 5 to 7 mm above anterior nasal spine on axial image. We evaluated the location of the greater palatine canal (line a: on the coronal view, the shortest line between the center of greater palatine canal and pterygoid fossa; distance a: the distance of line a). We also measured the thickness (line b: on the coronal view, the shortest line between maxillary posterior sinus wall and pterygoid fossa; distance b: distance of line b), width (line c: on the coronal view, the line perpendicular to the line b and the nearest line from the most concave point of lateral pterygoid plate to the medial pterygoid plate; distance c: distance of line c) and height (line d: on sagittal view, the vertically longest line of pterygoid junction; distance d: the distance of line d) in pterygomaxillary junctions. We evaluated the association between the obtained anatomic values and several variables (sex, age, height and weight). Results: The mean distance a was 4.78 mm, mean distance b was 5.53 mm, mean distance c was 8.01 mm and mean distance d was 13.22 mm. The differences between age and mean distance c and weight and mean distance d in pterygomaxillary junctions are statistically significant. Conclusion: There apparently is anatomic variation of pterygomaxillary junctions by various values, particularly weight and age in a Korean clinical population.

Design and Fabrication of 4-beam Silicon-Micro Piezoresistive Accelerometer for TPMS Application (TPMS용 4빔 실리콘 미세 압저항형 가속도센서의 설계 및 제작)

  • Park, Ki-Woong;Kim, Hyeon-Cheol
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.49 no.2
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    • pp.1-8
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    • 2012
  • This paper presents the accelerometer which is a key component of TPMS(Tire Pressure Monitoring System). Generally a piezoresistive accelerometer has characteristics of lower cost, better linearity and better immunity about the environmnet noise than a capacitive one. Three types of piezoresistive accelerometers are degined and simulated using ANSYS program. The best one is a piezoresistive sensor which is supported by four beams located at the center of the edge of the mass after comparing the characteristics of resonant frequency of the three types. Considering the sensor size and a simulated maximum stress and maximum displacement, the length of beams is set as $200{\mu}m$. The size of a piezoresistive accelerometer is $3.0mm{\times}3.0mm{\times}0.4mm$. The sensor output is characterized by measuring the output characteristic depending on angle. As a result the offset voltage of the accelerometer is 43.2 mV and its sensitivity is $42.5{\mu}V/V/g$. The temperature bias drift is measured. The shock durability of the sensor is 1500g and the measuring range is 0 ~ 60 g.

Impacts of Irradiation Sources on Quality Attributes of Low-salt Sausage during Refrigerated Storage

  • Song, Dong-Heon;Kim, Hyun-Wook;Hwang, Ko-Eun;Kim, Yong-Jae;Ham, Youn-Kyung;Choi, Yun-Sang;Shin, Dong-Jin;Kim, Tae-Kyung;Lee, Jae Hoon;Kim, Cheon-Jei;Paik, Hyun-Dong
    • Food Science of Animal Resources
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    • v.37 no.5
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    • pp.698-707
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    • 2017
  • This study was performed to investigate the impacts of irradiation sources on quality attributes of low-salt sausage during refrigerated storage. Control sausage was prepared with 1.5% sodium chloride (NaCl), whereas low-salt sausage was formulated with 0.75% NaCl (a 50% reduction; L-control). Sausage samples were vacuum-packaged, and low-sausages were irradiated with gamma-ray, electron-beam and X-ray at 5 kGy, respectively. The samples were stored at $4^{\circ}C$ for 28 d to determine changes in quality attributes. The pH of low-salt sausages was unaffected by irradiation at 5 kGy (p>0.05). Higher redness values were found at irradiated low-salt sausages compared to control (p<0.05). The hardness, gumminess and chewiness of control sausage were higher than those of low-salt sausages (p<0.05). However, there were no significant differences in the textural parameters between low-salt sausage treatments. The overall sensory acceptability score of irradiated/low-salt sausages were lower than L-control due to decreased scores for cooked meat flavor but increased radiolytic off-flavor (p<0.05). The initial 2-thiobarbituric acid-reactive substances (TBARS) values of irradiated/low-salt sausages were higher than control and L-control (p<0.05). However, the TBARS values of irradiated treatments were significantly lower than control at the end of storage. Irradiation could effectively inhibit the microorganism growth (total aerobic bacteria, coliforms, Enterobacteriaceae, and Pseudomonas spp.) in low-salt sausages (p<0.05). Therefore, our findings show that irradiation could be to improve microbial safety of low-salt sausages, and suggest that further studies should be necessary to reducing radiolytic off-flavor of irradiated/low-salt sausages.