• Title/Summary/Keyword: Bc1-2

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Low Phase Noise VCO Using Novel Harmonic Control Circuit Based on Composite Right/Left-Handed Transmission Line (혼합 우좌향 전송 선로 기반의 새로운 고조파 조절 회로를 이용한 저위상 잡음 전압 제어 발진기)

  • Choi, Jae-Won;Seo, Chul-Hun
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.47 no.1
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    • pp.84-90
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    • 2010
  • In this paper, a novel voltage-controlled oscillator (VCO) using the harmonic control circuit based on the composite right/left-handed (CRLH) transmission lines (TLs) is presented to reduce the phase noise without the reduction of the frequency tuning range and miniaturize the circuit size. The phase noise is reduced by the novel harmonic control circuit having the short impedances for the second- and third-harmonic components. The proposed harmonic control circuit is designed by using the CRLH TLs with the dual-band characteristic by the frequency offset and phase slope of the CRLH TLs. The high-Q resonator has been used to reduce the phase noise, but has the problem of the frequency tuning range reduction. However, the frequency tuning range of the proposed VCO has not been reduced because the phase noise has been reduced without the high-Q resonator. The miniaturization of the circuit size is achieved by using the CRLH TLs instead of the conventional right-handed (RH) TLs. The phase noise of VCO is -119.17 ~ -117.50 dBc/Hz at 100 kHz in the tuning range of 5.731 ~ 5.938 GHz.

Design of 24-GHz 1Tx 2Rx FMCW Transceiver (24 GHz 1Tx 2Rx FMCW 송수신기 설계)

  • Kim, Tae-Hyun;Kwon, Oh-Yun;Kim, Jun-Seong;Park, Jae-Hyun;Kim, Byung-Sung
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.29 no.10
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    • pp.758-765
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    • 2018
  • This paper presents a 24-GHz frequency-modulated continuous wave(FMCW) radar transceiver with two Rx and one Tx channels in 65-nm complementary metal-oxide-semiconductor(CMOS) process and implemented it on a radar system using the developed transceiver chip. The transceiver chip includes a $14{\times}$ frequency multiplier, low-noise amplifier, down-conversion mixer, and power amplifier(PA). The transmitter achieves >10 dBm output power from 23.8 to 24.36 GHz and the phase noise is -97.3 GHz/Hz at a 1-MHz offset. The receiver achieves 25.2 dB conversion gain and output $P_{1dB}$ of -31.7 dBm. The transceiver consumes 295 mW of power and occupies an area of $1.63{\times}1.6mm^2$. The radar system is fabricated on a low-loss Duroid printed circuit board(PCB) stacked on the low-cost FR4 PCBs. The chip and antenna are placed on the Duroid PCB with interconnects and bias, gain blocks and FMCW signal-generating circuitry are mounted on the FR4 PCB. The transmit antenna is a $4{\times}4$ patch array with 14.76 dBi gain and receiving antennas are two $4{\times}2$ patch antennas with a gain of 11.77 dBi. The operation of the radar is evaluated and confirmed by detecting the range and azimuthal angle of the corner reflectors.

Contributive Estimation of Polycyclic Aromatic Hydrocarbons by Emission Source in Seoul Area (서울지역 대기 중 다환방향족탄화수소의 발생원별 기여도 평가)

  • Park, Chan-Koo;Yun, Joong-Sup;Eo, Soo-Mi;Shin, Jeong-Sik;Kim, Min-Young;Sohn, Jong-Ryeul;Mo, Sae-Young
    • Journal of Korean Society for Atmospheric Environment
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    • v.22 no.3
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    • pp.287-295
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    • 2006
  • PAHs (Polycyclic Aromatic Hydrocarbons), one of the carcinogenic materials in environment, were investigated in this study. The standardized analysis conditions were tested, and then various factors which affect to the ambient PAHs concentration in Seoul were estimated. Moreover, the emissions of PAHs from major stationary sources were investigated to determine the quantitative relationships between ambient PAHs concentrations and emission sources. From the factor analysis, three factors relevant to the ambient PAHs in Seoul were found. Factor 1 was related to the concentrations of chrysene, pyrene, indeno (1, 2, 3-cd)pyrene, benzo[b]fluoranthene, benzo[k]fluoranthene, and benzo prerylene which were mainly emitted from gasoline and diesel fueled cars. Factor 2 showed higher loadings in phenanthrene and anthracene which were due to LNG and BC oil combustion in industry and home. And factor 3 included dibenz(a, h)anthracene and acenaphthene which were emitted from open burning and municipal solid waste incineration. Conclusively, all of three factors were consisted in 82% of total variance. The contribution of mobile sources in ambient air in Seoul was estimated at 64%, that of industrial and home sources at 17%, and that of open burning and municipal incineration at 1%.

Noise Exposure according to the Time Activity Pattern and Duties of Firefighters (소방 공무원의 시간활동 양상과 직무에 따른 소음 노출 특성)

  • Lee, Lim-Kyu;Kang, Tae-Sun;Ham, Seung-Hon;Kim, Jung-In;Yang, Young-Suk;Yoon, Chung-Sik
    • Journal of Environmental Health Sciences
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    • v.37 no.2
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    • pp.94-101
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    • 2011
  • Objectives: The purpose of this study is to evaluate the noise exposures of firefighters according to their time-dependent activity patterns. Methods: Personal exposure levels were measured for six days and nights using noise dosimeters; three days and nights for on-duty tasks, the other days and nights for off-duty activities. Results: The total amount of time spent in the workplace was 13,677 min (67%), outside areas 4,833 min (23%), in transit 1,002 min (5%), and other indoor area 807 min (4%) during a working period. However, during off-days they spent 10,858 min (76%) at home, 1,382 min (10%) outdoors, 1,225 min (9%) other indoors, and 493 min (3%) in transit. As a result of individual exposure levels, TWA did not exceed 90 dBA of the occupational exposure limit for the majority of the firefighters, whereas the levels of Lmax were 119 dBA, which were higher than the noise levels of firefighters in USA. Sometimes during dispatching the levels of Lpeak exceeded the ACGIH exposure standard (140 dBC). The Leq levels in transit were higher than the levels in home and other indoors even though the activity time is short. Conclusions: This paper characterized the noise exposure patterns of firefighters in Korea. We suggest that special noise sources, including sirens and speaker phones, should be readjusted to reduce noise exposure.

Noise Exposure Assessment in a Dental School

  • Choosong, Thitiworn;Kaimook, Wandee;Tantisarasart, Ratchada;Sooksamear, Puwanai;Chayaphum, Satith;Kongkamol, Chanon;Srisintorn, Wisarut;Phakthongsuk, Pitchaya
    • Safety and Health at Work
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    • v.2 no.4
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    • pp.348-354
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    • 2011
  • Objectives: This cross-sectional study was performed in the Dental School of Prince of Songkla University to ascertain noise exposure of dentists, dental assistants, and laboratory technicians. A noise spectral analysis was taken to illustrate the spectra of dental devices. Methods: A noise evaluation was performed to measure the noise level at dental clinics and one dental laboratory from May to December 2010. Noise spectral data of dental devices were taken during dental practices at the dental services clinic and at the dental laboratory. A noise dosimeter was set following the Occupational Safety and Health Administration criteria and then attached to the subjects' collar to record personal noise dose exposure during working periods. Results: The peaks of the noise spectrum of dental instruments were at 1,000, 4,000, and 8,000 Hz which depended on the type of instrument. The differences in working areas and job positions had an influence on the level of noise exposure (p < 0.01). Noise measurement in the personal hearing zone found that the laboratory technicians were exposed to the highest impulsive noise levels (137.1 dBC). The dentists and dental assistants who worked at a pedodontic clinic had the highest percent noise dose (4.60 ${\pm}$ 3.59%). In the working areas, the 8-hour time-weighted average of noise levels ranged between 49.7-58.1 dBA while the noisiest working area was the dental laboratory. Conclusion: Dental personnel are exposed to noise intensities lower than occupational exposure limits. Therefore, these dental personnel may not experience a noise-induced hearing loss.

A Cost-Benefit Analysis of Groundwater: Pumping Wells in Korea (지하수의 경제성 평가 연구: 지하수 관정을 중심으로)

  • Kim, Sun Geun
    • Economic and Environmental Geology
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    • v.47 no.3
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    • pp.219-225
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    • 2014
  • In Korea, there are 1,474 thousand pumping wells nationwide which account for about 12% of total water use in 2012. As much as 39 hundred million tons of groundwater were used while 333 hundred million tons of total water were supplied in 2012. Because the water management authority projects that water demand will exceed supply by 2021, the authority is planning to extensively expand groundwater use in accordance with economic feasibility. Using the basic frameworks of cost-benefit analyses of the World Bank and the US Environmental Protection Agency (US EPA), the objective of this study is to examine the costs and benefits of the expansion of Korea's groundwater extraction through pumping wells. We conclude that the BC ratio of the groundwater pumping wells is 2.98. This signifies that the benefits are 2.98 times higher than the costs. The benefits include use and non-use values of pumping wells while the costs include the installation and maintenance of new wells, in addition to the restoration and pollution costs of abandoned wells, as well as fees for water quality tests, etc.

A Cost-Benefit Analysis of Groundwater Supply through Pumping Well Technology

  • Kim, Sun G.
    • Proceedings of the Korea Technology Innovation Society Conference
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    • 2015.11a
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    • pp.479-487
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    • 2015
  • In Korea, there are 1,474 thousand pumping wells nationwide which account for about 12% of total water use in 2012. As much as 39 hundred million tons of groundwater were used while 333 hundred million tons of total water were supplied in 2012. Because the water management authority projects that water demand will exceed supply by 2021, the authority is planning to extensively expand groundwater use in accordance with economic feasibility. Using the basic frameworks of cost-benefit analyses of the World Bank and the US Environmental Protection Agency (US EPA), the objective of this study is to examine the costs and benefits of the expansion of Korea's groundwater extraction through pumping wells. We conclude that the BC ratio of the groundwater pumping wells is 2.98. This signifies that the benefits are 2.98 times higher than the costs. The benefits include use and non-use values of pumping wells while the costs include the installation and maintenance of new wells, in addition to the restoration and pollution costs of abandoned wells, as well as fees for water quality tests, etc.

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$\beta$-Glucan enhanced apoptosis in human colon cancer cells SNU-C4

  • Kim, Mi-Ja;Hong, Se-Young;Kim, Sun-Kyu;Cheong, Chul;Park, Hong-Ju;Chun, Hye-Kyung;Jang, Ki-Hyo;Yoon, Byung-Dae;Kim, Chul-Ho;Kang, Soon-Ah
    • Nutrition Research and Practice
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    • v.3 no.3
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    • pp.180-184
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    • 2009
  • The apoptotic effect of bacteria-derived $\beta$-glucan was investigated in human colon cancer cells SNU-C4 using terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end labeling (TUNEL) assay, reverse transcription-polymerase chain reaction (RT-PCR) expressions of Bcl-2, Bax, and Caspase-3 genes, and assay of caspase-3 enzyme activity. $\beta$-Glucan of 10, 50, and $100{\mu}g$/mL decreased cell viability in a dose-dependent manner with typical apoptotic characteristics, such as morphological changes of chromatin condensation and apoptotic body formation from TUNEL assay. In addition, $\beta$-glucan ($100{\mu}g$/mL) decreased the expression of Bc1-2 by 0.6 times, whereas the expression of Bax and Caspase-3 were increased by 3.1 and 2.3 times, respectively, compared to untreated control group. Furthermore, the caspase-3 activity in the $\beta$-glucan-treated group was significantly increased compared to those in control group (P < 0.05). Bacterial derived $\beta$-glucan could be used as an effective compound inducing apoptosis in human colon cancer.

Studies on hematologic values and types of blood protein in Jindo dogs II. Types of blood protein of Jindo dogs (진도견(珍島犬)의 혈액상(血液像)과 혈액단백질형(血液蛋白質型)에 관(關)한 연구(硏究) II. 진도견(珍島犬)의 혈액단백질형(血液蛋白質型))

  • Kim, Woo-kwon;Han, Bang-keun;Kim, Ja-suk
    • Korean Journal of Veterinary Research
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    • v.28 no.2
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    • pp.299-305
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    • 1988
  • The phenotypes of hemoglobin, albumin and transferrin of 3U2 Jindo dogs in Jindo area were studied by starch gel electrophoresis for hemoglobin and albumin, and by polyacrylamide gradient gel electrophoresis for transferrin. The results obtained were as follows: 1. In the hemoglobin phenotypes, three phenotypes, HbAA, HbAB and HbBB, which were controlled by two allelic genes, $Hb^A$ and $Hb^B$, were observed and their frequencies of appearance were 1.65%, 10.60% and 87.75% respectively. The distribution of gene frequency was calculated as 0.0695 in $Hb^A$ and 0.9305 in $Hb^B$. 2. In the albumin phenotypes, three phenotypes, Alb FF, Alb FS and Alb SS, which were controlled by two allelic genes, $AIb^F$ and $AIb^S$ were observed and their frequencies of appearance were 12.59%, 25.56% and 61.85% respectively. The distribution of gene frequency was calculated as 0.2537 in $AIb^F$ and 0.7463 in $AIb^S$. 3. Analysis of transferrin phenotypes showed 6 different types which were controlled by three allelic genes, $Tf^B$, $Tf^C$ and $Tf^D$ and their frequencies of appearance were 54.04% in TfBB, 17.54% in TfBC, 9.82% in TfBD, 8.07% in TfCC, 7.37% in TfCD and 3.16% in TfDD. The distribution of gene frequency was calculated as 0.6772 in $Tf^B$, 0.2053 in $Tf^C$ and 0.1175 in $Tf^D$.

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The Slow and Tight Binding of MR-387A to Aminopeptidase N

  • CHUNG, MYUNG-CHUL;HYO-KON CHUN;HO-JAE LEE;CHOONG-HWAN LEE;SU-IL KIM;YUNG-HEE KHO
    • Journal of Microbiology and Biotechnology
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    • v.6 no.4
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    • pp.250-254
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    • 1996
  • MR-387A [(2S, 3R)-2-hydroxy-3-amino-4-phenylbutanoyl-L-valyl-L-prolyl-(2, 4-trans)- L-4-hydroxy-proline] reversibly inhibits aminopeptidase N (BC 3.4.11.2) in a process that is remarkable for its unusual degree of time dependence. The time required to inactivate the enzyme by 50$%$ ($t_{1/2}$) for establishing steady-state levels of $EI^*$complex was approximately 5 minutes. This indicates that the inhibition is a slow-binding process. In dissociation experiments of $EI^*$ complex, enzymic activity was regained slowly in a quadratic equation, indicating that the inhibition of aminopeptidase N by MR-387A is tight-binding and reversible. Thus, the binding of MR-387A by aminopeptidase N is slow and tight, with $K_{i}$ (for initial collision complex, EI) and $K_i{^*}$ (for final tightened complex, $EI^*$) of $2.2\times10^{-8}$ M (from Lineweaver-Burk plot) and $4.4\times10^{-10}$ M (from rate constants), respectively. These data indicate that MR-387A and aminopeptidase N are bound approximately 200-fold more tightly in the final $EI^*$complex than in the initial collision EI complex.

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