• Title/Summary/Keyword: Baseline Correction

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Surgical Ligation on Significant Patent Ductus Arteriosus in Very Low Birth Weight Infants: Comparison between Early and Late Ligations

  • Lee, Jun Ho;Ro, Sun Kyun;Lee, Hyun Ju;Park, Hyun Kyung;Chung, Won-Sang;Kim, Young Hak;Kang, Jeong Ho;Kim, Hyuck
    • Journal of Chest Surgery
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    • v.47 no.5
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    • pp.444-450
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    • 2014
  • Background: We aimed to evaluate the efficacy and safety of early surgical ligation (within 15 days of age) over late surgical ligation (after 15 days of age) by a comparative analysis of very low birth weight (VLBW) infants undergoing surgical correction for symptomatic patent ductus arteriosus (PDA) over the course of 6 years in our hospital. Methods: We retrospectively reviewed all the medical records in the neonatal intensive care unit at Hanyang University Seoul Hospital, from March 2007 to May 2013, to identify VLBW infants (<1,500 g) who underwent surgical PDA ligation. Results: The gestational age (GA) in the late ligation (LL) group was significantly younger than in the early ligation (EL) group (p=0.010). The other baseline characteristics and preoperative conditions did not differ significantly between the two groups. The intubation period before surgery (p<0.001) and the age at surgery (p<0.001) were significantly different. The postoperative clinical outcomes of the study patients, including major morbidity and mortality, are summarized. There were no significant differences in bronchopulmonary dysplasia, sepsis, or mortality between the EL and the LL groups. However, the LL group was significantly associated with an increased risk of necrotizing enterocolitis (p=0.037) and with a prolonged duration of the total parenteral nutrition (p=0.046) after adjusting for GA. Conclusion: Early surgical ligation for the treatment of PDA that failed to close after medical treatment or in cases contraindicated for medical treatment might be desirable to reduce the incidence of necrotizing enterocolitis and to alleviate feeding intolerance in preterm infants.

Hypoadrenocortical Crisis-like Transient Hyponatremia and Hyperkalemia in a Near-Term Pregnant Dog (분만 직전의 개에서 급성 부신겉질저하증과 유사한 일과성 저나트륨혈증 및 고칼륨혈증 일례)

  • Kang Ji-houn;Kim Min-jun;Cho Min-haeng;Chang Dong-woo;Kang Hyun-gu;Kim Ill-hwa;Na Ki-jeong;Yang Mhan-pyo
    • Journal of Veterinary Clinics
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    • v.22 no.4
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    • pp.450-452
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    • 2005
  • A 3-year-old, 43kg, pregnant Great Pyrenese was examined for clinical signs of acute weakness and anorexia for 4 days. The dog was in lateral recumbency at referral. The rectal temperature was within reference range, and the respiratory and heart rates were 36 breaths/min and 58 beats/min, respectively. The abdomen was distended, and several puppies were palpated. The mean fetal head diameter was 2.8cm in the ultrasonographic examination. The initial complete blood count and serum biochemical examinations revealed mild dehydration, mud hyperglycemia, hypochloremia, hyperkalemia, hyponatremia, and low sodium-potassium ratio. Serum BUN and total cholesterol values were slightly high. Hypoadrenocortical crisis was suspected on the basis of signs of acute collapse, hyponatremia and hyperkalemia. Adrenal gland function was evaluated by an ACTH stimulation test. The baseline cortisol concentration was $18.6{\mu}g/dl$ and the concentration at 1 hour after administration of tetracosactrin (ACTH, Synacthen) was $8{\mu}g/dl$. The dog was treated for the correction of assumed hypoadrenocortical crisis and substantial hyperkalemia. In addition to rapid infusion with saline solution, other medications administered intravenously included sodium bicarbonate and cimetidine hydrochloride. The dog was monitored with repeated serum electrolyte examination. After clinical stabilization, cesarean section was performed. All of 13 puppies were delivered, and the dog recovered from anesthesia without complications. The values of postpartum blood tests returned to normal or within reference range. The dog remained healthily.

Effects of Tracheal Suction and Method of Bronchodilator Inhalation on Vital Signs and Pulmonary functions in Patients with Open Heart Surgery(OHS) (심장수술 환아에게 기도흡인과 기관지 확장제의 투여 방법이 활력징후 및 폐기능에 미치는 효과)

  • Song Hyo-Sook;Jun Tae-Gook;Park Pyo-Won;Kim Kyoung-Eun;Chung Ji-Hye
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.10 no.1
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    • pp.96-107
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    • 2003
  • Objective: The purpose of this study was to identify the effects of tracheal suction and the effects of different methods of bronchodilator inhalation (Ultrasonic nebulizer: MDI puff, MDI puff with spacer) in VSD surgery patients. Material & Method: From June 2001 to March 2002, sixty consecutive patients were randomly assigned to a control group (n= 15), ultrasonic nebulizer group (n=15), metered dose inhalation (MDI) puff group (n=15) and MDI with spacer group (n=15). Vital signs (HR, BP, CVP), ABGA and pulmonary functions were measured before suction (baseline for suction), after suction, 15 minutes after suction (base of bronchodilator inhalation), 30 minutes after bronchodilator inhalation, and 2 hours after bronchodilator inhalation. Stastistical analysis was performed using SPSS software. Repeated measure ANOVA was used to examine the effects of tracheal suction. One way ANOVA with Bonferroni's correction and multiple range test (the least significant difference test) were used to examine the effects of albuterol inhalation. Result: 1. Heart .ate increased significantly immediately after suction (p<.01) and recovered 15 minutes after suction. 2. $PaO_2$ and PH decreased significantly immediately after suction (p<.05) and $PaO_2$ recovered 15 minutes after suction. $PaCO_2$ increased immediately after suction and significantly 15 minutes after suction (p<.01). But changes in vital signs and ABGA were within the normal range. 3. Tidal volume decreased significantly 15 minutes after suction (p<.05). 4. Changes of HR and tidal volume were greater in the nebuizer group compared to the other groups (p<.05) 30 minutes after bronchodilator inhalation and recovered 2 hours after bronchodilator inhalation. 5. Changes of airway deadspace was greater in the nebulizer group compared to the control group and MDI puff group 30 minutes after albuterol inhalation (p<.05) and at 2 hours (p<.01). Conclusion: Tracheal suction did not have significant effect on vital signs and pulmonary functions after OHS. Although the methods of bronchodilator inhalation did not showed any significant difference on pulmonary function, the nebulizer method increased $PaO_2$ (20%) and tidal volume transiently. If the patient needs bronchodilator inhalation with bronchospasm after OHS, the nebulizer method is the best choice. More study on the effects of bronchodilator inhalation in bronchospasm group is needed.

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Augmentation of Pyriform Margin Using Porous High-Density Polyethylene Sheet In Unilateral Cleft Lip Nasal Deformity (일측성 구순열비변형에서 다공성 폴리에틸렌 판을 이용한 상악골이상구증대술)

  • Han, Ki Hwan;Kim, Jin Han;Choi, Tae Hyun;Kim, Jun Hyung;Son, Dae Gu
    • Archives of Plastic Surgery
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    • v.35 no.4
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    • pp.431-438
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    • 2008
  • Purpose: The common deformity after the correction of unilateral cleft lip nasal deformity is nasal asymmetry, and it is caused by the hypoplasia of the pyriform aperture. To correct this, many procedures have been applied, but still many problems are present. Authors performed the inlay and onlay insertion of porous high density polyethylene sheet(1 mm thickness $Medpor{(R)}$ sheet) in the hypoplastic pyriform margin of cleft side and obtained satisfactory results. Methods: 11 cases were performed and the mean follow up period was 15.1 months. Their mean age was 23.6 years. Under general anesthesia, bilateral pyriform margin was exposed. $Medpor{(R)}$ sheets in "match stick" like shaped were inlay inserted, and kidney shaped were onlay inserted fixating with two 6 mm titanium screws. After the surgery, the results was evaluated by photogrammetric analysis. On the basal view, the distance from the subalare and labiale superius' to the transverse baseline connecting the both cheilions was measured from the cleft side and the non-cleft side. Then, the postoperative symmetry was assessed by obtaining the cleft side against the non-cleft side as proportion index, defined as lateral and medial upper lip contour index. Results: There were 2 infections. The cause was because the inserted implant was too long and thus protruded to the base of nasal cavity. The lateral upper lip contour index was from 95.49 to 103.27, and medial upper lip contour index was from 90.92 to 100.49, it was statistically increased, and thus the symmetry was improved. However clinically mild depression remained at nostril floor. Conclusion: Authors performed porous high density polyethylene sheet inlay and onlay insertion for the hypoplasia of the pyriform margin in unilateral cleft lip nasal deformity. It was found that depressed pyriform margin and upper lip were corrected effectively except for the nostril floor, for which an additional soft tissue augmentation would be necessary. The inlay insertion has risk of protrusion, thus the guideline of the use of artificial prosthesis should be observed strictly.

Long-term prediction of streamflow for water resource management in Geumho River watershed (중장기 하천유량 관리를 위한 금호강 유역의 유출량 예측)

  • Kim, Han Na;Park, Jung Eun;Kang, Shin Uk;Lee, Eul Rae
    • Proceedings of the Korea Water Resources Association Conference
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    • 2015.05a
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    • pp.416-416
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    • 2015
  • 기후변화는 미래 강수량 변동을 야기하여 하천유량 관리에 큰 영향을 미칠 것으로 예상하고 있다. 이에 본 연구에서는 기후변화에 따른 중장기 하천유량 관리를 위하여 금호강 유역을 대상으로 SWAT 모형을 이용하여 중장기 하천유량을 예측하였다. 임하댐 상류지역의 2008~2012년 유량자료에 대하여 보정 완료된 SWAT 모형을 기반으로, 지역기후모형(RCM)인 HadGEM3-RA모형을 활용한 IPCC 제5차 보고서 RCP 4.5, RCP 8.5 시나리오를 적용하였다. 금호강 표준유역별 기후변화에 의한 영향을 모의하기 위하여 편이보정(Bias Correction)방법을 적용하였으며, 금호강 유역 내 과거 30년(1975~2005년, Baseline) 기상자료와 비교하여 통계적인 유사성을 가지도록 보정을 실시하였다. 기후변화 시나리오 적용결과는 S1(2011~2040년), S2(2041~2070년), S3(2071~2099년)으로 분할하여 월별, 계절별, 연도별 미래 강수량과 기온을 분석하였다. 분석 결과, RCP 4.5 시나리오의 경우 봄철(3~5월)의 강수량은 기준년도에 비해 약 57%가 증가하였으나, 가을철(6~8월)에는 7.9% 감소하였으며, 첨두 강수시기는 8~9월에서 6~7월로 이동하였다. 평균기온은 각 구분 시기별 $0.2^{\circ}C$, $1.1^{\circ}C$, $1.8^{\circ}C$ 정도 상승할 것으로 예측되었다. RCP 8.5 시나리오에서는 기준년도 대비 강우량은 봄철에 61% 증가, 가을철에는 14.9% 감소하는 것으로 모의되었다. 평균기온은 약 $0.4^{\circ}C$, $2.1^{\circ}C$, $4.2^{\circ}C$ 정도 상승하는 것으로 나타났다. 기후변화에 따른 유출량 결과 비교는 2001~2010년을 기준으로 하였으며, RCP 4.5 시나리오에서는 S1, S2, S3 시기별 각각 -10.9%, -7%, -3.6% 감소하였으며, RCP 8.5 시나리오에서는 약 -12.3%, 4.9%, -1.2% 변동하는 것으로 나타냈다. 금호강 유역 전반에 걸쳐 유출량이 감소하는 추세를 보였으며, 특히 본류에 비해 지류유역의 건천화가 심해지는 양상을 보였다. 또한 현재에 비해 여름철 유출패턴 시기가 앞당겨져 봄철 유량이 증가하고 겨울철에 감소하는 경향을 보이고 있다. 기후변화로 인한 수문패턴의 변화로 현재 하천유량관리의 변화가 필요할 것으로 판단되며, 향후 본 연구결과를 바탕으로 물수지 분석을 추가하여 유지유량 만족을 위한 해당유역의 이수기 유량관리 방안 연구를 수행할 예정이다.

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Development of Underwater Positioning System using Asynchronous Sensors Fusion for Underwater Construction Structures (비동기식 센서 융합을 이용한 수중 구조물 부착형 수중 위치 인식 시스템 개발)

  • Oh, Ji-Youn;Shin, Changjoo;Baek, Seungjae;Jang, In Sung;Jeong, Sang Ki;Seo, Jungmin;Lee, Hwajun;Choi, Jae Ho;Won, Sung Gyu
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.3
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    • pp.352-361
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    • 2021
  • An underwater positioning method that can be applied to structures for underwater construction is being developed at the Korea Institute of Ocean Science and Technology. The method uses an extended Kalman filter (EKF) based on an inertial navigation system for precise and continuous position estimation. The observation matrix was configured to be variable in order to apply asynchronous measured sensor data in the correction step of the EKF. A Doppler velocity logger (DVL) can acquire signals only when attached to the bottom of an underwater structure, and it is difficult to install and recover. Therefore, a complex sensor device for underwater structure attachment was developed without a DVL in consideration of an underwater construction environment, installation location, system operation convenience, etc.. Its performance was verified through a water tank test. The results are the measured underwater position using an ultra-short baseline, the estimated position using only a position vector, and the estimated position using position/velocity vectors. The results were compared and evaluated using the circular error probability (CEP). As a result, the CEP of the USBL alone was 0.02 m, the CEP of the position estimation with only the position vector corrected was 3.76 m, and the CEP of the position estimation with the position and velocity vectors corrected was 0.06 m. Through this research, it was confirmed that stable underwater positioning can be carried out using asynchronous sensors without a DVL.

Plant Species Richness in Korea Utilizing Integrated Biological Survey Data (생물기초조사 통합자료를 활용한 우리나라 식물종 풍부도 분석)

  • Seungbum Hong;Jieun Oh;Jaegyu Cha;Kyungeun Lee
    • Korean Journal of Ecology and Environment
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    • v.56 no.4
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    • pp.363-374
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    • 2023
  • The limitation in deriving the species richness representing the entire country of South Korea lies in its relatively short history of species field observations and the scattered observation data, which has been collected by various organizations in different fields. In this study, a comprehensive compilation of the observation data for plants held by agencies under the Ministry of Environment was conducted, enabling the construction of a time series dataset spanning over 100 years. The data integration was carried out using minimal criteria such as species name, observed location, and time (year) followed by data verification and correction processes. Based on the integrated plant species data, the comprehensive collection of plant species in South Korea has occurred predominantly since 2000, and the number of plant species explored through these surveys appears to be converging recently. The collection of species survey data necessary for deriving national-level biodiversity information has recently begun to meet the necessary conditions. Applying the Chao 2 method, the species richness of indigenous plants estimated at 3,182.6 for the 70-year period since 1951. A minimum cumulative period of 7 years is required for this estimation. This plant species richness from this study can be a baseline to study future changes in species richness in South Korea. Moreover, the integrated data with the estimation method for species richness used in this study appears to be applicable to derive regional biodiversity indices such as for local government units as well.

Accuracy Assessment of Tide Models in Terra Nova Bay, East Antarctica, for Glaciological Studies of DDInSAR Technique (DDInSAR 기반의 빙하연구를 위한 동남극 테라노바 만의 조위모델 정밀도 평가)

  • Han, Hyangsun;Lee, Joohan;Lee, Hoonyol
    • Korean Journal of Remote Sensing
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    • v.29 no.4
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    • pp.375-387
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    • 2013
  • Accuracy assessment of tide models in polar ocean has to be performed to accurately analyze tidal response of glaciers by using Double-Differential Interferometric SAR (DDInSAR) technique. In this study, we used 120 DDInSAR images generated from 16 one-day tandem COSMO-SkyMed DInSAR pairs obtained for 2 years and in situ tide height for 11 days measured by a pressure type wave recorder to assess the accuracy of tide models such as TPXO7.1, FES2004, CATS2008a and Ross_Inv in Terra Nova Bay, East Antarctica. Firstly, we compared the double-differential tide height (${\Delta}\dot{T}$) for Campbell Glacier Tongue extracted from the DDInSAR images with that predicted by the tide models. Tide height (T) from in situ measurement was compared to that of the tide models. We also compared 24-hours difference of tide height ($\dot{T}$) from in situ tide height with that from the tide models. The root mean square error (RMSE) of ${\Delta}\dot{T}$, T and $\dot{T}$ decreased after the inverse barometer effect (IBE)-correction of the tide models, from which we confirmed that the IBE of tide models should be corrected requisitely. The RMSE of $\dot{T}$ and ${\Delta}\dot{T}$ were smaller than that of T. This was because $\dot{T}$ is the difference of tide height during temporal baseline of the DInSAR pairs (24 hours), in which the errors from mean sea level of the tide models and in situ tide, and the tide constituents of $S_2$, $K_2$, $K_1$ and $P_1$ used in the tide models were canceled. This confirmed that $\dot{T}$ and ${\Delta}\dot{T}$ predicted by the IBE-corrected tide models can be used in DDInSAR technique. It was difficult to select an optimum tide model for DDInSAR in Terra Nova Bay by using in situ tide height measured in a short period. However, we could confirm that Ross_Inv is the optimum tide model as it showed the smallest RMSE of 4.1 cm by accuracy assessment using the DDInSAR images.