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Biological Activity of Fermented Silkworm Powder (발효누에분말의 생리활성)

  • Cha, Jae-Young;Kim, Yong-Soon;Ahn, Hee-Young;Eom, Kyung-Eun;Park, Bo-Kyung;Jun, Bang-Sil;Cho, Young-Su
    • Journal of Life Science
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    • v.19 no.10
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    • pp.1468-1477
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    • 2009
  • The comparative effects of the fibrinolytic, and tyrosinase inhibition activities and electrophoretical protein patterns with freeze-drying silkworm powder (FDSW), heating-drying silkworm powder (HDSW) and fermented silkworm powder by Bacillus subtilis or Lactobacillus hilgardii were investigated. When total protein patterns of FDSW, HDSW, both fermented SW, were analyzed by native- and SDS-polyacrylamide gel electrophoresis (PAGE), there were slightly varietal differences in electrophoretical protein patterns. Major minerals of FDSW and HDSW were K, Ca, Mg, and Zn. Major compositional amino acids of FDSW and HDSW were glycine, alanine, glutamic acid, aspartic acid, and serine. Major fatty acids of FDSW and HDSW were linolenic acid, oleic acid, and palmitic acid. Fibriolytic activity was the highest in the fermented FDSW by 5% B. subtilis among the various samples. Tyrosinase inhibition activity was higher in the water and 70% methanolic extract of FDSW than in HDSW. DPPH radical scavenging activity was slightly stronger in HDSW than in FDSW. In addition, DPPH radical scavenging activity was higher in FDSW or HDSW fermented by L. hilgardii than that fermented by B. subtilis, however, all samples exhibited a relatively low activity compared to the butylated hydroxytoluene (BHT). These results may provide the basic data to understand the biological activities of fermented SW.

A Study on Fire Spread and Evacuation Risk of Conduit Combustion in Ceiling Hiding Place (천장 은폐장소 전선관 연소에 따른 화재확산 및 피난 위험도에 관한 연구)

  • Park, Kwang-Muk;Jeon, Jae-Kam;Bang, Sun-Bae
    • Fire Science and Engineering
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    • v.34 no.1
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    • pp.55-65
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    • 2020
  • In this study, the ISO 5660 and ISO 5659 combustion tests were conducted with synthetic resin conduits (CD, VE) and metal conduit (ST) used for wiring work in electrical facilities, which can be installed in ceiling concealed places. Then, fire spreading and evacuation risks were analyzed based on the measured data. In the ISO 5660 test, CD of 120.5 MJ/㎡, VE of 81.9 MJ/㎡, and ST of 4.9 MJ/㎡ were measured. In the ISO 5659 test, the CD 1320, VE 731, and ST 102 were measured, and then the maximum smoke densities were measured for CD 605 s, VE 740 s, and ST 1,200 s. In terms of fire spreading and evacuation risk, the CD conduit, VE conduit, and ST conduit were in order. In the fire spreading risk analysis, total heat emission was calculated as 4,820 MJ/㎡, 4,267 MJ/㎡, and 196 MJ/㎡ for CD, VE, and ST, respectively. Evacuation risk analysis shows at transmittance of 89%, CD is 127 s, VE is 35 s, and ST is 969 s. At transmittance of 79%, representing almost invisible concentration, CD is 157 s and VE is 50 s. The CD and VE conduits had a high fire spreading and evacuation risks, while the ST conduit had little effect on fire spreading and evacuation risk.

Comparison of IVF-ET Outcome after Various Therapeutic Approaches for Ovarian Endometriomas (난소의 자궁내막종에 대한 다양한 치료적 적용에 따른 체외수정 및 배아이식술 결과의 비교 연구)

  • Lee, Bang-Hyun;Kwon, Hyuck-Chan;Lee, Jae-Hyun;Kim, Bo-Hyun;Lee, Sang-Hee;Park, Min-Hye;Lee, Byung-Kwan;Lim, Jung-Ae
    • Clinical and Experimental Reproductive Medicine
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    • v.31 no.2
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    • pp.95-103
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    • 2004
  • Objective: To compare COH characteristics and IVF outcomes among IVF-ET patients who were treated with various therapeutic modalities for ovarian endometriomas and to propose effective pre-cyclic therapeutic modalities to improve IVF-ET outcomes in the patients with ovarian endometriomas. Methods: All cases that had undergone IVF-ET after laparoscopy between January 1997 to August 2003 were reviewed. Forty-eight patients with tubal factor were assigned to Group I. Twenty seven, 22 and 38 patients diagnosed as severe pelvic adhesion with ovarian endometriomas by laparoscopy received only medical therapy (Group II), cyst aspiration (Group III), and sclerotherapy (Group IV), respectively. Laparoscopic cystectomy was performed in 20 patients (Group V). Resistance index was measured on day administering hCG. Results: As compared with Group I, in Group II resistance index increased (p<0.05) but number of oocytes, good-quality oocyte ratio (mature and intermediate oocytes/total retrieval oocytes), fertilization rate, and embryo development rate decreased (p<0.05). In Group III fertilization rate and embryo development rate decreased (p<0.05). There was no difference between Group IV and Group I in all parameters except basal FSH which increased (p<0.05). In Group V basal FSH, and resistance increased (p<0.05) and number of oocytes and good-quality oocytes ratio decreased (p<0.05). Conclusion: Sclerotherapy is an effective therapeutic option which can be done prior to IVF-ET cycles in the patients with ovarian endometriomas. Further studies on a large scale are necessary to confirm these data.

Knowledge and Attitudes of Oncology Nurses Toward Cancer Pain Managements (암 병동 간호사의 통증관리에 대한 지식과 태도)

  • Gong, Soung-Wha;Bang, Jji-Yha;Seo, Min-Sook;Hyun, Sin-Sook;Kim, Hee-Jung;Lee, Mi-Ae;Lee, Mi-Ae;You, Hyen-Hee;Her, Jae-Kyoung;Kim, Eun-Ae;Park, Kyung-Sook
    • Korean Journal of Adult Nursing
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    • v.16 no.1
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    • pp.5-16
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    • 2004
  • Purpose: The purpose of this study is to evaluate the knowledge and attitudes of oncology ward nurses toward cancer pain management and to find ways to improve the educational program for nurses. Method: A total of 209 nurses working at the oncology ward of three hospitals in Seoul and a Gyenggi Province. The survey instrument used was the 32-item scale for evaluating nurses knowledge and attitudes originally developed by McCaffery and Ferrell'(1990), that was by Kim'(1997). Result: In terms of the nurses knowledge of pain management, the result showed that the nurses scored an average of 67.8 out of 100 for phamacokinetics of opioids, 84.8 for classification of analgesics, 60.1 for pain assessment, and 70.7 for drug administration. 18.2% of the nurses hesitate to inject the narcotic agent because of concerns regarding the drug's potential side effects. there was significant difference in the knowledge of pain management according to the general characteristics of pain in terms of the nurses age(p=.001), position (p=.016), years of experiences(p=.002), experience of cancer pain education(p=.001). Conclusion: The also showed that nurses working at cancer ward lack knowledge. It is important to provide intensive education to nurses about cancer pain management.

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Effect of Zn content on Shear Strength of Sn-0.7Cu-xZn and OSP surface finished Joint with High Speed Shear Test (Sn-0.7Cu-xZn와 OSP 표면처리 된 기판의 솔더접합부의 고속 전단강도에 미치는 Zn의 영향)

  • Choi, Ji-Na;Bang, Jae-Oh;Jung, Seung-Boo
    • Journal of the Microelectronics and Packaging Society
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    • v.24 no.1
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    • pp.45-50
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    • 2017
  • We investigated effect of Zn content on shear strengh of Sn-0.7Cu-xZn and OSP surface finished solder joints. Five pastes of Sn-0.7Cu-xZn (x=0, 0.5, 1.0, 1.5, 2.0 wt.%) solders were fabricated by mixing of solder powder and flux using planatary mixer. $180{\mu}m$ diameter solder balls were formed on OSP surface finished Cu electrodes by screen print method, and the reflow process was performed. The shear strength was evaluated with two high shear speeds; 0.01 and 0.1 m/s. The thickness of the intermetallic compound(IMC) layer was decreased with increasing Zn content in Sn-0.7Cu-xZn solder. The highest shear strength was 3.47 N at the Zn content of 0.5 wt.%. As a whole, the shear strength at condition of 0.1 m/s was higher than that of 0.01 m/s because of impact stress. Fracture energies were calculated by F-x (Force-displacement) curve during high speed shear test and the tendency of fracture energy and that of shear strength were good agreement each other. Fracture took place within solder matrix at lower Zn content, and fracture occured near the interface of OSP surface finished Cu electrode and solder at higher Zn content.

Species and Hybrid Identification of Genus Coreoleuciscus Species in Hwnag-ji Stream, Nakdong River Basin in Korea (낙동강 상류 황지천에 서식하는 쉬리속(genus Coreoleuciscus) 어류 집단의 종 동정 및 잡종 판별)

  • Song, Ha-Yoon;Kim, Jae-Hun;Seo, In-Young;Bang, In-Chul
    • Korean Journal of Ichthyology
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    • v.29 no.1
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    • pp.1-12
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    • 2017
  • A natural hybrid of interspecific between the Coreoleuciscus splendidus and C. aeruginos (Cypriniformes: Cyprinidae) was captured in the Hwang-ji Stream, a tributary of the Nakdong River basin in Korea. An interspecific hybrid between C. splendidus and C. aeruginos was genetically identified based on morphological characteristics and the sequence analysis of nuclear recombination activating gene 1 (RAG1) gene (1,334 bp) and mitochondrial cytochrome c oxidase subunit 1 (CO1) gene (1,551 bp). As a result of morphological variations, the natural hybrid appeared to have an intermediate character between two parental species (C. splendidus and C. aeruginos) in three variations of black array (s) on dorsal, caudal and anal fin rays. Phylogenetic analysis inferred from RAG1 and CO1 sequence data revealed that Coreoleuciscus populations from Hwang-ji stream consist of two pure Coreoleuciscus species and a hybrid individual group. The individuals were clearly identified the cross and reciprocal hybrid by CO1 gene analysis. In RAG1 gene, 13 nucleotide variation loci were detected and the hybrid individuals displayed the double peaks of sequence chromatograms at the 9 diagnostic positions. In this study, molecular data and morphological variations were clearly demonstrated that hybridization did occur between C. splendidus and C. aeruginos. However, F2 hybrid generation and reproductive capacity of F1 hybrid individuals were not demonstrated.

Performance Improvement of Single Chip Multiprocessor using Concurrent Branch Execution (분기 동시 수행을 이용한 단일 칩 멀티프로세서의 성능 개선)

  • Lee, Seung-Ryul;Kim, Jun-Shik;Choi, Jae-Hyeok;Choi, Sang-Bang
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.44 no.2
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    • pp.61-71
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    • 2007
  • The instruction level parallelism, which has been used to improve the performance of processors, expose its limit. The change of a control flow by a branch miss prediction is one of the obstacles that restrict the instruction level parallelism. The single chip multiprocessors have been developed to utilize the thread level parallelism. However, we could not use the maximum performance of the single chip multiprocessor in case of executing the coded programs without considering the multi-thread. In order to overcome the two performance degradation factors, in this paper, we suggest the concurrent branch execution method that applies to the multi-path execution method at a single chip multiprocessor. We executes all two flows of the conditional branch using the idle core processor. Through this, we can improve the processor's efficiency with blocking the control flow termination by the branch instruction and reducing the idle time. We analyze the effects of concurrent branch execution proposed in this paper through the simulation. As a result of that, concurrent branch execution reduces about 20% of idle time and improves the maximum 10% of the branch prediction accuracy. We show that our scheme improves the overall performance of maximum 39% compared to the normal single chip multiprocessor and maximum 27% compared to the superscalar processor.

Effect of Lighting Regimes on Performance and Meat Quality of Broilers (점등체계가 육계의 생산성과 육질특성에 미치는 영향)

  • Na, Jae Cheon;Park, Sung Bok;Kang, Hwan Ku;Kim, Dong Wook;Kim, Min Ji;Bang, Han Tae;Chae, Hyun-Seok;Choi, Hee Chul;Suh, Ok Suk;Hong, Eui Chul
    • Journal of Animal Environmental Science
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    • v.18 no.3
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    • pp.173-182
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    • 2012
  • The study was carried out to investigate the effect of lighting regimes on performance and meat quality of broiler. A total of 912 chicks was divided into 2 groups with male (3 replications/group, 34 heads/replication) and female (3 replications/group, 42 heads/replication). Treatments were control (C, natural lighting), T1 treatment (24L), and T2 treatment (1~2d, 24L; 2~4d, 23L+1D; 4~16d, 16L+8D; 16~21d, 18L+6D; 21~42d, 23L+1D) by lighting regimes. There was no significantly different on body weight, body weight gain, feed intake, and feed conversion ratio of male and female of broilers among treatments. There was no significantly different on cooking loss and water hold capacity of all broiler's meats among treatments. Share force of lighting regimes was higher compared to control (P<0.05). There was no significantly different on common ingredients (moisture, crude protein, crude fat, and ash) of broiler's meat. Finally, lighting regimes may decrease the stress as well as improve the growth performance and meat quality of broilers

An Experimental Study on Flow Distributor Performance with Single-Train Passive Safety System of SMART-ITL (SMART-ITL 1 계열 피동안전계통을 이용한 유동분사기 성능에 대한 실험연구)

  • Ryu, Sung Uk;Bae, Hwang;Yang, Jin Hwa;Jeon, Byong Guk;Yun, Eun Koo;Kim, Jaemin;Bang, Yoon Gon;Kim, Myung Joon;Yi, Sung-Jae;Park, Hyun-Sik
    • Journal of Energy Engineering
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    • v.25 no.4
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    • pp.124-132
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    • 2016
  • In order to estimate the effect of flow distributors connected to an upper nozzle of CMT(Core Makeup Tank) on the thermal-hydraulic characteristics in the tank, a simplified 2 inch Small Break Loss of Coolant Accident(SBLOCA) was simulated by skipping the decay power and Passive Residual Heat Removal System(PRHRS) actuation. The CMT is a part of safety injection systems in the SMART (System Integrated Modular Advanced Reactor). Each test was performed with reliable boundary conditions. It means that the pressure distribution is provided with repeatable and reproducible behavior during SBLOCA simulations. The maximum flow rates were achieved at around 350 seconds after the initial opening of the isolation valve installed in CMT. After a short period of decreased flow rate, it attained a steady injection flow rate after about 1,250 seconds. This unstable injection period of the CMT coolant is due to the condensation of steam injected into the upper part of CMT. The steady injection flow rate was about 8.4% higher with B-type distributor than that with A-type distributor. The gravity injection during hot condition tests were in good agreement with that during cold condition tests except for the early stages.

Clinical Study of Composite Valve Graft Replacement of the Aortic Root (대동맥 근부 복합 인공 판막 도관 치환술에 관한 임상적 고찰)

  • Park, Kwon-Jae;Woo, Jong-Soo;Cho, Gwang-Jo;Bang, Jung-Hee;Jeong, Sang-Seok
    • Journal of Chest Surgery
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    • v.43 no.3
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    • pp.260-265
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    • 2010
  • Background: A composite valve graft replacement has been used for a variety of aortic root diseases. The aim of this study was to evaluate the mid-term results of this technique. Material and Method: We conducted a retrospective analysis of aortic root composite valve graft replacements in 39 patients and these procedures were done at our institution between 1992 and 2009. The mean age of the patients was $49.2{\pm}16.4$ years. The mean follow-up was $64.2{\pm}53.4$ months (maximum: 176 months). Result: There were 4 hospital deaths (8.6%) due to emergency aortic dissection and 4 late deaths owing to several causes. The causes of late death were 2 ruptures of a remnant aneurysm, 1 subdural hemorrhage and 1 paravalvular leakage. The calculated survival rate was 93.5%, 85.0% and 85.0% at 1, 5 and 10 years, respectively. There were 3 cerebrovascular accidents during the follow up period. The rate of freedom from cerebrovascular accidents was 97.0%, 92.0% and 80.0% at 1, 5 and 10 years, respectively. All of these brain accidents were hemorrhage-related complications. Conclusion: A composite valve graft replacement of the aortic root was associated with favorable results. So, this technique seems to be a good method to treat various aortic root diseases.