• The Journal of Asian Finance, Economics and Business
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• 제9권2호
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• pp.113-120
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• 2022

The goal of this study is to see if there's a relationship between employees' ambidextrous behaviors and macro facilitators of organizational empowerment (such as control over workplace decisions, dynamic structural framework, and fluidity in information sharing) (exploration and exploitation). To acquire data, this study uses survey methods. A cross-sectional survey was done to collect information from academics at five large public sector universities in Pakistan's Balochistan province. Control over workplace decisions boosts academics' engagement in exploration and exploitation, while a dynamic structural framework merely increases their engagement in exploration, according to the findings based on data from 240 respondents (n = 240). The findings also show that information sharing flexibility has little effect on exploration and exploitation behaviors. In conclusion, the results of this study imply that organizational empowerment is critical for academics' ambidextrous behaviors to thrive. As a result, specific organizational facilitators of empowerment (such as control over workplace decisions and a dynamic structural framework) are advised in higher education institutions. This research is significant because it develops and tests a model that explains hitherto unexplored connections between macro facilitators of organizational empowerment and employees' ambidextrous behaviors. In addition, the research provides important insights for managerial practice and research.

• Asian Pacific Journal of Cancer Prevention
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• 제13권8호
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• pp.4013-4016
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• 2012

Purpose: Breast cancer is the commonest malignancy of females throughout the world with one million new cases each year. In Pakistan, the burden of breast cancer disease is high with late stage presentation being a common feature, more than half being stage III or stage IV. The objective of this study was to study various aspects, patterns and risk factors in breast cancer patients of Balochistan. Method: Present study was performed on 134 patients of breast cancer who were registered in CENAR. The patients were interviewed by providing a questionnaire. Informed consent was taken from all the patients who took part in this study after explanation of the study aims. Body mass index (BMI) was calculated andbiopsy reports were obtained from patients files. All the cases were classified with respect to age, gender, ethnic group (Baloch, Pashtoon, Punjabi, Afghani, Hazara) BMI, cancer type, cancer grade, hormonal status, side of the cancer, fertility and marital status. Results: Out of 134 patients, the most common ethnic group was Pashtoon with a total of 42 and the common age group was 41-50 years with a total of 51. Invasive ductal carcinoma (IDC) was the most common type, accounting for in 128 patients (95.5%) followed by invasive lobular carcinoma (ILC). Conclusion: Pashtoon was the most common ethnic group, IDC was common type and most of the patients had an ER/PR positive hormonal status.

• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3623-3626
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• 2016

Breast cancer is very common and the leading cause of cancer deaths among women globally. Hereditary cases account for 5-10% of the total burden and CHEK2, which plays crucial role in response to DNA damage to promote cell cycle arrest and repair or induce apoptosis, is considered as a moderate penetrance breast cancer risk gene. Our objective in the current study was to analyze mutations in related to breast cancer. A total of 271 individuals including breast cancer patients and normal subjects were enrolled and all 14 exons of CHEK2 were amplified and sequenced. The majority of the patients (>95%) were affected with invasive ductal carcinoma (IDC), 52.1% were diagnosed with grade III tumors and 56.2% and 27.5% with advanced stages III and IV. Two novel nonsense variants i.e. c.58C>T (P.Q20X) and c.256G>T (p.E85X) at exon 1 and 2 in two breast cancer patients were identified, both novel and not reported elsewhere.

• The Journal of Asian Finance, Economics and Business
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• 제7권7호
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• pp.349-360
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• 2020

The study aims to empirically examine the determinants of bank margins from Pakistan, an emerging South Asian economy. To elucidate the importance of the Pakistani banking sector, secondary data has been used, which was extracted from the annual accounts of twenty-four Pakistani scheduled commercial banks (20 conventional, four full-fledged Islamic) over a sample period of 2006 to 2017. The factors identified in the dealership model and the subsequent empirical developments in the dealership model categorized as bank-specific, diversification, regulatory, and industry concentration are analyzed by applying the most-common linear dynamic panel-data estimator, the Generalized Method of Moments (GMM) estimator, developed by Arellano and Bond (1991). The findings reveal that, among the bank-specific variables, funding cost, credit risk, managerial efficiency, market share, and operating cost are significant predictors of bank margins. For diversification variables employed in the study, both variables including net non-interest income and asset diversity are as well significant predictors of bank margins. It is also found that the market concentration variable proxied by the Herfindahl-Hirschman Index (HHI) is significantly predicting bank margins. Subsequently, one of the regulatory variables, the opportunity cost of holding reserves, and one bank-specific variable, the degree of risk aversion, are insignificant in the model.

• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1089-1092
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• 2016

Breast cancer is the most commonly occurring and leading cause of cancer deaths among women globally. Hereditary cases account 5-10% of all the cases and CHEK2 is considered as a moderate penetrance breast cancer risk gene. CHEK2 plays a crucial role in response to DNA damage to promote cell cycle arrest and repair DNA damage or induce apoptosis. Our objective in the current study was to analyze mutations in the CHEK2 gene related to breast cancer in Balochistan. A total of 271 individuals including breast cancer patients and normal subjects were enrolled. All 14 exons of CHEK2 were amplified and sequenced. The majority of the patients (>95%) had invasive ductal carcinomas (IDCs), 52.1% were diagnosed with tumor grade III and 56.1% and 27.5% were diagnosed with advance stages III and IV. Two novel nonsense variants i.e. c.58C>T (P.Q20X) and c.256G>T (p.E85X) at exon 1 and 2 in two breast cancer patients were identified in the current study. Both the variants identified were novel and have not been reported elsewhere.

• Asian-Australasian Journal of Animal Sciences
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• 제3권2호
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• pp.85-89
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• 1990

Sixteen Harnai lambs were used in a completely randomized design to study the nutritive value of fourwing saltbush as a winter maintenance browse in comparison to native range grazing with or without protein and energy supplementation at Tomagh Range Livestock Research Station, in Loralai District, Balochistan. The animals were divided into four groups of four lambs each. These four groups were assigned four treatments at random: fourwing saltbush grazing alone, range grazing plus lucerne hay (100 g/head/day), range grazing plus barley grain (100 g/head/day) and range grazing alone for ten weeks. The results indicate that the two range grazing plus supplementation treatments produced weight gains which were not significantly different from each other (p < 0.05). Both of these treatments yielded significantly higher weight gains (p < 0.05) than did range grazing alone except for the last week of the study. Fourwing saltbush grazing provided cumulative weight gains at 3, 4, 6, 7 and 8 weeks which were not significantly different from the range grazing plus lucerne hay treatment and gained an average of 6 percent in body weight over the 10 week period of study. The carrying capacity for sheep of a mature stand of fourwing saltbush was approximately 20 Sheep-kg-days (SKD) of grazing per cubic meter of foliage. Results of this study suggest that under fourwing saltbush grazing alone, lambs do not only maintain their body weights but can also gain weight in winter.

• International Journal of Computer Science & Network Security
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• 제24권4호
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• pp.147-154
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• 2024

The continuous increase in urban population due to migration of mases from rural areas to big cities has set urban water supply under serious stress. Urban water resources face scarcity of available water quantity, which ultimately effects the water supply. It is high time to address this challenging problem by taking appropriate measures for the improvement of water utility services linked with better understanding of demand side management (DSM), which leads to an effective state of water supply governance. We propose a dynamic framework for preventive DSM that results in optimization of water resource management. This paper uses Agent Based Modeling (ABM) with Digital Twin (DT) to model water consumption behavior of a population and consequently forecast water demand. DT creates a digital clone of the system using physical model, sensors, and data analytics to integrate multi-physical quantities. By doing so, the proposed model replicates the physical settings to perform the remote monitoring and controlling jobs on the digital format, whilst offering support in decision making to the relevant authorities.

• Asian-Australasian Journal of Animal Sciences
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• 제4권4호
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• pp.333-339
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• 1991

Eighty-two ewes of Balochi breed, two to four years of age were used in a completely randomized design to study the effect of winter supplementation on their performance in Kalat area of Balochistan and randomly divided into two groups of 40 and 42 animals. Two treatments (T1 and T2) studied were : 250 gm/animal/day of a 50 : 50 mixture of cottonseed cake and barley grain fed from Oct. 20 to Dec. 18, 1988 plus grazing and 500 gm/animal/day of the same feed mixture fed from Oct. 9 to Dec. 18, 1988 in addition to grazing. Lucerne hay and wheat straw in a 50 : 50 ratio were provided to all the ewes for a period of one month from Jan. 6, 1989 @ 320 gm/animal/day to sustain them in severe winter. Same feeding levels to the same ewe groups were again fed from Mar. 1 to May 27, 1989. Three breeding rams stayed with the flock from Nov. 1 to Dec. 13, 1988. Lambing took place from Apr. 2 to May 12, 1989. Conception, lambing and mortality percentage was found different (P<.05) between T1 and T2 (12.5 vs 14.8 kg). The ewes on T2 maintained higher body weights throughout winter than the ewes on T1. The results are suggestive of improvement in conception rate with winter supplementation (flushing) and decrease in ewe mortality. Late-gestation and early-lactation supplemental feeding of ewes results in increases in weaning weights of their lambs.

• ALGAE
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• 제26권4호
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• pp.317-325
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• 2011

Five benthic species of the genus Gambierdiscus (Dinophyceae) were observed for the first time in the coastal waters of Pakistan, Northern Indian Ocean. The morphology of the epiphytic, ciguatera-related toxic species G. toxicus, G. belizeanus, G. polynesiensis, G. australes and G. cf. yasumotoi are presented here, described by the Kofoid system of thecal plates Po, 3', 7", 6c, 8s, 5"', 1p, 2"" with differences in cell shape, cell size, plates, pores around the apical pore plate by using light and scanning electron microscopy. The occurrence of these potentially toxic dinoflagellate species in Pakistani coastal areas of Manora Channel and Balochistan during high temperatures of 28-$32^{\circ}C$ is cause of concern for human health impacts from ciguatera fish poisoning.

• Asia Marketing Journal
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• 제17권3호
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• pp.53-72
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• 2015

Social media marketing have drawn substantial attention in business and academia. This study examines the impact of social media marketing on purchase intention of consumer in South Korea and Pakistan. The research background rests on literature of social media, social media marketing, electronic word of mouth and social media advertisement. Descriptive research method is adopted for the purpose of this study. The findings indicated that South Korean users have higher intention to purchase products through social media platforms as compared to users in Pakistan. The results also show that electronic word of mouth has greater influence on purchase intention as compared to advertisement on social networks. Managerial implications and limitations of the study results were also discussed.