• Title/Summary/Keyword: Back filler

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Effect of bFGF and fibroblasts combined with hyaluronic acid-based hydrogels on soft tissue augmentation: an experimental study in rats

  • Lee, Su Yeon;Park, Yongdoo;Hwang, Soon Jung
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.41
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    • pp.47.1-47.10
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    • 2019
  • Background: Hyaluronic acid (HA) has been applied as a primary biomaterial for temporary soft tissue augmentation and as a carrier for cells and the delivery of growth factors to promote tissue regeneration. Although HA derivatives are the most versatile soft tissue fillers on the market, they are resorbed early, within 3 to 12 months. To overcome their short duration, they can be combined with cells or growth factors. The purpose of this study was to investigate the stimulating effects of human fibroblasts and basic fibroblast growth factors (bFGF) on collagen synthesis during soft tissue augmentation by HA hydrogels and to compare these with the effects of a commercial HA derivative (Restylane®). Methods: The hydrogel group included four conditions. The first condition consisted of hydrogel (H) alone as a negative control, and the other three conditions were bFGF-containing hydrogel (HB), human fibroblast-containing hydrogel (HF), and human fibroblast/bFGF-containing hydrogel (HBF). In the Restylane® group (HGF), the hydrogel was replaced with Restylane® (R, RB, RF, RBF). The gels were implanted subdermally into the back of each nude mouse at four separate sites. Twelve nude mice were used for the hydrogel (n = 6) and Restylane® groups (n = 6). The specimens were harvested 8 weeks after implantation and assessed histomorphometrically, and collagen synthesis was evaluated by RT-PCR. Results: The hydrogel group showed good biocompatibility with the surrounding tissues and stimulated the formation of a fibrous matrix. HBF and HF showed significantly higher soft tissue synthesis compared to H (p < 0.05), and human collagen type I was well expressed in HB, HF, and HBF; HBF showed the strongest expression. The Restylane® filler was surrounded by a fibrous capsule without any soft tissue infiltration from the neighboring tissue, and collagen synthesis within the Restylane® filler could not be observed, even though no inflammatory reactions were observed. Conclusion: This study revealed that HA-based hydrogel alone or hydrogel combined with fibroblasts and/or bFGF can be effectively used for soft tissue augmentation.

Ballistic impact response of Kevlar Composites with filled epoxy matrix

  • Pekbey, Yeliz;Aslantas, Kubilay;Yumak, Nihal
    • Steel and Composite Structures
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    • v.24 no.2
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    • pp.191-200
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    • 2017
  • Impact resistance and weight are important features for ballistic materials. Kevlar fibres are the most widely reinforcement for military and civil systems due to its excellent impact resistance and high strength-to-weight ratio. Kevlar fibres or spectra fiber composites are used for designing personal body armour to avoid perforation. In this study, the ballistic impact behaviour of Kevlar/filled epoxy matrix is investigated. Three different fillers, nanoclay, nanocalcite and nanocarbon, were used in order to increase the ballistic impact performance of Kevlar-epoxy composite at lower weight. The filler, nanoclay and nanocalcite, content employed was 1 wt.% and 2 of the epoxy resin-hardener mixture while the nanocarbon were dispersed into the epoxy system in a 0.5%, 1% and 2% ratio in weight relating to the epoxy matrix. Specimens were produced by a hand lay-up process. The results obtained from ballistic impact experiments were discussed in terms of damage and perforation. The experimental tests revealed a number of damage mechanisms for composite laminated plates. In the ballistic impact test, it was observed whether the target was perforated completely penetrated at the back or not. The presence of small amounts of nanoclay and nanocalcite dispersed into the epoxy system improved the impact properties of the Kevlar/epoxy composites. The laminates manufactured with epoxy resin filled by 1 wt.% of nanoclay and 2 wt% nanocalcite showed the best performance in terms of ballistic performance. The addition of nanocarbon reduced ballistic performance of Kevlar-epoxy composites when compared the results obtained for laminates with 0% nanoparticles concentration.

Comparisons of Thermal Insulations between on Air-Cell Pack Embedded Jacket and Down Jackets (공기주입형 의복의 보온력 측정 및 다운재킷의 보온력과의 비교)

  • Kim, Yung-Bin;Jang, Won;Kim, Kirim;Kim, Siyeon;Baek, Yoon Jeong;Lee, Joo-Young
    • Journal of the Korean Society of Clothing and Textiles
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    • v.39 no.1
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    • pp.55-62
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    • 2015
  • This study investigated the thermal insulation of an air-cell pack embedded jacket and down jackets to understand the potential of air-cell pack as a filler for winter outdoor wear. A thermal manikin measured the thermal insulation of the following jackets: HD (heavy down jacket, total weight (Tw) 750g, goose down weight (Dw) 350g), LD (light down jacket, Tw 560g, Dw 140g), AF (air-cell pack embedded jacket, Tw 490g, trunk goose down in LD was replaced to air cell), F (film jacket, Tw 469g, but removed the air in the air-cell pack from the AF), and Control (control jacket, Tw 438g, removed the air-cell pack film from the F). Thermal insulations of each experimental condition were measured in a static standing posture. Total thermal insulations (IT) were 1.29clo (HD), 1.23clo (LD), 1.16clo (AF), 1.20clo (F), and 1.08clo (Control). Body regional thermal insulation was higher in the chest and back than in the abdomen and hip in all conditions. The results suggest that an economical and versatile outdoor jacket with superior thermal insulation will be feasible if the air volume is properly controlled in air-cell pack embedded jackets in consideration of regional different distribution and used in combination with film and down.

Establishment of Western-style Court Dress and its Formal Characteristics in the Meiji Period of Japan (일본 메이지기 [明治期] 문관대례복의 성립과 형태적 특징)

  • Lee, Kyung-Mee
    • Journal of the Korean Society of Costume
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    • v.60 no.5
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    • pp.71-87
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    • 2010
  • The purpose of the study is analyzing Japanese modern costume, through examining legislation process and the relics of Chickimkwan's and Juimkwan's court costume. The results of the study are as follows. First, the proposer of civil court costume, established in 1872, was Iwakura Mission dispatched to America and Europe. The Mission realized the importance of preparing western-style costume in civilization from experience wearing traditional clothing at ceremony of presenting credentials in America. Afterwards, the Mission proposed that the government accept western-style as civil court costume and became first wearers in Japanese in England. Second, the difference, between ordinance and actual clothes worn by Iwakura Mission, occurred in process of legislation in 1872. That might be considered as trial and error in introducing different culture. The coexistence of England and French styles was unified into French style by the revision of civil court costume in 1886. Third, the pattern of paulownia embroidered on civil court costume was utilized as symbol of Japan. While the costume of Chickimkwan was embroidered by the pattern of 7 and 5 leaves paulownia, that of Juimkwan was 5 and 3 leaves expressing their grades. Fourth, relics research showed how formed manufacturer information and enacted design were in embroidery. The relics seemed to be manufactured in Japan, because emblem of Mitsukosi tailor was embroidered on inner part of the back of collar of Chickimkwan in Nara Women's University, Japan and that of Yamasaki on left inner pocket of Juimkwan in the Independence Hall, Korea. The embroider techniques comprised forming by filler particles according to the design, filling up coiled gold threads and expressing stem with gold threads and spangles. As preemptive study, establishment process of Japanese civil court costume in this study will help understand form characteristics appeared in civil court costume act of Korean Empire.

A Research On the T-DMB Received Environment For the Efficient Reuse of the Band of VHF Frequency (VHF대역의 효율적 재활용을 위한 T-DMB 수신환경 조사)

  • Park, Sung-Kyu;Lee, Sang-Un;Chae, Su-Hyun;Park, Gooman
    • Journal of Broadcast Engineering
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    • v.21 no.5
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    • pp.726-738
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    • 2016
  • This study analyzed the properties of VHF band and suggested an efficient VHF band application plan for digital radio and UHDTV broadcasting through the experiment by the house T-DMB device in practical user environment. In order to find an efficient frequency band for digital radio broadcasting, this study examined first, to check the times of drop-out receive occurring in the audible area using a DMB/FM CAR Radio for T-DMB that has the characteristics of DAB. Second, this article explored the phenomenon of feedback loops in the same channel using a T-DMB house gap filler transmitting the signal by the same OFDM modulation scheme with UHDTV for configuring suitable SFN transmission network of the UHDTV broadcasting. Based on these experiments, this study suggested a suitable VHF band for digital radio and an efficient utilization of the VHF frequency band for the SFN network configuration of UHDTV.

Study of the Curing Time of Cementless Cold Central Plant Recycled Asphalt Base-Layer through Field-Application Review (무시멘트 상온 재활용 아스팔트 기층의 현장 적용성을 통한 양생기간에 관한 연구)

  • Choi, Jun Seong;Jung, Chul Ho;Lee, Chan Hee;Lim, in su
    • International Journal of Highway Engineering
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    • v.19 no.2
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    • pp.67-74
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    • 2017
  • PURPOSES : The objective of this study is to ascertain the curing period of cementless cold central plant recycled asphalt base-layer, using mechanical analyses and specimen quality tests on the field. METHODS : Cold central plant recycled asphalt base-layer mixture was produced in the plant from reclaimed asphalt, natural aggregate, filler for the cold mix, and the modified emulsion AP using asphalt mix design and plant mix design. In order to examine the applicability of the curing period during the field test, the international standards for the possibility of core extraction and the degree of compaction and LFWD deflection were analyzed. Moreover, Marshall stability test, porosity test, and indirect tensile strength test were performed on the specimens of asphalt mix and plant mix design. RESULTS : The plant production process and compaction method of cementless cold central plant recycled asphalt base-layer were established, and the applicability of the optical moisture content for producing the mixture was verified through the field test. In addition, it was determined that the core extraction method of the conventional international curing standard was insufficient to ensure performance, and the LFWD test demonstrated that the deflection converges after a two-day curing. However, the back-calculation analysis reveals that a three-day curing is satisfactory, resulting in a general level of performance of dense asphalt base-layer. Moreover, from the result of the specimen quality test of the asphalt mix design and plant mix design according to the curing period, it was determined that the qualities satisfied both domestic and international standards, after a two-day curing. However, it was determined that the strength and stiffness after three-day curing are higher than those after a two-day curing by approximately 3.5 % and 20 %, respectively. CONCLUSIONS:A three-day curing period is proposed for the cementless cold central plant recycled asphalt base-layer; this curing period can be demonstrated to retain the modulus of asphalt-base layer in the field and ensure stable quality characteristics.

Characteristics of Thermal Radiation Pastes Containing Graphite and Carbon Nanotube (흑연 및 탄소나노튜브 혼합 방열도료의 특성)

  • Lee, Ji Hun;Song, Man-Ho;Kang, Chan Hyoung
    • Journal of the Korean institute of surface engineering
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    • v.49 no.2
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    • pp.218-224
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    • 2016
  • Thermal radiation pastes were prepared by dispersing carbon materials as fillers with a content of 1 weight percent in an acrylic resin. The kind of fillers was as follows; $25{\mu}m$ graphite, $45{\mu}m$ graphite, $15{\mu}m$ carbon nanotube(CNT), a 1:1 mixture of $25{\mu}m$ graphite and $15{\mu}m$ CNT, and a 1:1 mixture of $45{\mu}m$ graphite and $15{\mu}m$ CNT. Thermal emissivity was measured as 0.890 for the samples with graphite only, 0.893 for that with CNT only, and 0.892 for those containing both. After coating prepared pastes on a side of 0.4 mm thick aluminium plate and placing the plate over an opening of a box maintained at $92^{\circ}C$ with the coated side out, the temperatures on the uncoated side of the plates were measured. The samples containing graphite and CNT showed the lowest temperatures. The paste with mixed fillers was coated on the back side of the PCB of an LED module and thermal analysis was carried out using Thermal Transient Tester (T3ster) in a still air box. The thermal resistance of the module with coated PCB was measured as 14.34 K/W whereas that with uncoated PCB was 15.02 K/W. The structure function analysis of T3ster data revealed that the difference between junction and ambient temperatures was $13.8^{\circ}C$ for the coated case and $18.0^{\circ}C$ for the uncoated. From the infrared images of heated LED modules, the hottest-spot temperature of the module with coated PCB was lower than that of the uncoated one for a given period of LED operation.