• Asian-Australasian Journal of Animal Sciences
• /
• v.5 no.3
• /
• pp.481-485
• /
• 1992

In order to upgrade native sheep, Rambouillet (R) rams were mated to Kaghani (K) ewes to generate F1 ($R{\times}K$) crossbred ewes. Crossbred ewes were backcrossed to Rambouillet rams to produce B1 ($R{\times}F1$), B2 ($R{\times}B1$) and B3 ($R{\times}B2$) genotypes. Weaning weight of 2605 lambs and wool weight of 2378 mature ewe records, representing R, K, F1, B1, B2 and B3 genotypes, were analyzed to compare genetic variation among genotypes produced during upgrading process and identify genotypes of the highest performance. Performance of Rambouillets was also evaluated under semi-temperate climate. Data were adjusted for yearly variation considering Rambouillet as a control. Genotypes influenced lambs weaning weight (p<.01). B1 lambs were heaviest (18.4 kg) followed in order by B2, F1, B3, R and K lambs (18.3, 17.9, 16.9, 16.8 and 13.2 kg, respectively). The highest wool production was 2.5 kg from R ewes followed by B2 (2.3), B3 (2.3), F1 (2.0) and K (1.2) ewes (p < .01). Ewe mating weight, reproduction, growth and wool production of Rambouillets deteriorated significantly after the first decade of their importation. Compared with the first phase (1959-1971), ewe mating weight, litter size, birth weight, lamb weaning weight and wool production declined by 20, 23, 32 and 36%, respectively, in the second phase (1972-1988).

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.40 no.2
• /
• pp.355-362
• /
• 2015

In this study, we have fabricated 9.385[GHz] circulator that is composed of WR112 waveguide and Ferrite for X-band radar. For designing Ferrite, B/R mode(Below Resonance mode) was used and calculated the condition of 120 degree rotation of the electric field in Ferrite and calculated internal DC magnetic field and external DC magnetic field. Also, dielectric materials of the same shape with Ferrite was filled between two Ferrite for improving the performance of the circulator, including impedance matching, bandwidth, quality factor, insertion loss. To obtain optimum shape of the Ferrite and dielectric material, we used CST MWS. Simulation result of the circulator is that 1.02 : 1 VSWR, -40dB isolation, 0.2dB insertion loss and measurement result is that 1.03 : 1, -38dB, 1.2dB at 9.385[GHz]. We can get good agreement at isolation and VSWR, but insertion loss was 1 dB great than simulation result.

• Journal of the Korean Magnetics Society
• /
• v.5 no.5
• /
• pp.427-431
• /
• 1995

The influence of Nd and B contents on the magnetic properties and structures of ${\alpha}-Fe$ based Nd-(Fe,Co)-B-Mo-Cu alloys was investigated. $Nd_{4}{(Fe_{0.9}Co_{0.1})}_{92-x}B_{x}Mo_{3}Cu_{1}$ and $Nd_{x}{(Fe_{0.9}Co_{0.1})}_{86-x}B_{10}Mo_{3}Cu_{1}$ amorphous alloys prepared by rapid solidification process were crystallized to form nanocrystalline structure. The increase of B content in $Nd_{4}{(Fe_{0.9}Co_{0.1})}_{92-x}B_{x}Mo_{3}Cu_{1}$ nanocrystalline resulted in the change of stucture of soft phase in the sequence of ${\alpha}-Fe$->${\alpha}-Fe+Fe_{3}B$->$Fe_{3}B$. The coercivitis of the alloys were increased with increasing B content and was 263 kA/m at x=18. On the contrary, the remanence has shown an opposite trends. The increase of Nd content in $Nd_{x}{(Fe_{0.9}Co_{0.1})}_{86-x}B_{10}Mo_{3}Cu_{1}$ nanocrystalline containing ${\alpha}-Fe$ as main phase had no effect on the structure and improved coercivity up to 256 kA/m. However, the remanence was decreased from 1.4 T to 1.15 T according to the increase of Nd content.

• Journal of Information Technology Services
• /
• v.4 no.1
• /
• pp.1-13
• /
• 2005

Many buying and selling companies have participated in B2B electronic commerce in order to boost sales and cut down purchase prices respectively. There are some studies on buying and selling companies performances of using B2B e-marketplaces which provide electronic B2B transaction services such as finding transaction partners, providing on-line transaction process like auctioneering, etc. This study investigates the critical failure factors against B2B e-marketplace in other words B2B market-maker or B2B intermediary. We proposed 4 hypotheses asserting that 4 critical failure factors make reverse effects on B2B intermediary performances. We adopt the Balanced Score Card (BSC) framework to evaluate B2B intermediary performance. Data were collected from 46 respondents of B2B intermediaries in Korea. Analyses showed that traditional off-line B2B practices like refunding to buyer or transactions without legal documents and low quality of product information and catalog are critical failure factors against B2B intermediary performance.

• BMB Reports
• /
• v.49 no.4
• /
• pp.238-243
• /
• 2016

The efficacy of anticancer drugs depends on a variety of signaling pathways, which can be positively or negatively regulated. In this study, we show that SETDB1 HMTase is down-regulated at the transcriptional level by several anticancer drugs, due to its inherent instability. Using RNA sequence analysis, we identified FosB as being regulated by SETDB1 during anticancer drug therapy. FosB expression was increased by treatment with doxorubicin, taxol and siSETDB1. Moreover, FosB was associated with an increased rate of proliferation. Combinatory transfection of siFosB and siSETDB1 was slightly increased compared to transfection of siFosB. Furthermore, FosB was regulated by multiple kinase pathways. ChIP analysis showed that SETDB1 and H3K9me3 interact with a specific region of the FosB promoter. These results suggest that SETDB1-mediated FosB expression is a common molecular phenomenon, and might be a novel pathway responsible for the increase in cell proliferation that frequently occurs during anticancer drug therapy.

• The Korean Journal of Food And Nutrition
• /
• v.7 no.2
• /
• pp.95-99
• /
• 1994

In order to investigate the fatty acid composition of Korean pumpkins, this study was designed. Three samples of Korean pumpkins, A(yellowish ripe), B(unripe, 30 days old) and C(unripe, 20 days old) were used for fatty acid analysis by gas chromatography. The results were as follows : Pumkin C, B and A showed 10, 12 and 15 kinds of fatty acids, respectively. In case of palmitic acid(C16:0), pumpkin C, B and A showed 22.5%, 22.9% and 26.6%, respectively. In case of u linolenic acid(C18:3), pumpkin C, B and A showed 22.6%, 23.6% and 44.8%, respectively. In case of palmitoleic acid(Cl6:1), pumpkin C. B and A showed 12.4%, 10.1% and 0.5%, respectively. In case of oleic acid(C18:1), pumpkin C. B and A showed 9.2%, 7.7% and 2.8%, respectively, In case of stearic acid(C18:0), pumpkin C, B and A showed B.S%, 3.7% and 3.5%, respectively. The ratio of P/S was 1.4, 1.6 and 1.9 for sample C, B and A, respectively. The ratio of w-3/w-6 was 1.1, 0.9 and 2.6 for sample C, B and A, respectively. Through this study, the ripe pumpkin(sample A) was thought to be good enough in nutritional aspects of fatty acids, particularly a-linoleic acid, Cl8 : 3(u-3) series.

• Journal of applied mathematics & informatics
• /
• v.28 no.1_2
• /
• pp.325-331
• /
• 2010

Let a and b be nonnegative integers with 2 $\leq$ a < b, and let G be a Hamiltonian graph of order n with n > $\frac{(a+b-5)(a+b-3)}{b-2}$. An [a, b]-factor F of G is called a Hamiltonian [a, b]-factor if F contains a Hamiltonian cycle. In this paper, it is proved that G has a Hamiltonian [a, b]-factor if $\delta(G)\;\geq\;\frac{(a-1)n+a+b-3)}{a+b-3}$ and $\delta(G)$ > $\frac{(a-2)n+2{\alpha}(G)-1)}{a+b-4}$.

• Journal of the Chungcheong Mathematical Society
• /
• v.23 no.2
• /
• pp.231-236
• /
• 2010

Using the properties of the concave function, we show that the Hausdorff dimension of the product $C_{\frac{a+b}{2},\frac{a+b}{2}}{\times}C_{\frac{a+b}{2},\frac{a+b}{2}}$ of the same symmetric Cantor sets is greater than that of the product $C_{a,b}{\times}C_{a,b}$ of the same anti-symmetric Cantor sets. Further, for $1/e^2$ < a, b < 1/2, we also show that the dimension of the product $C_{a,a}{\times}C_{b,b}$ of the different symmetric Cantor sets is greater than that of the product $C_{\frac{a+b}{2},\frac{a+b}{2}}{\times}C_{\frac{a+b}{2},\frac{a+b}{2}}$ of the same symmetric Cantor sets using the concavity. Finally we give a concrete example showing that the latter argument does not hold for all 0 < a, b < 1/2.

• The Korean Journal of Physiology and Pharmacology
• /
• v.27 no.4
• /
• pp.325-331
• /
• 2023

α₁-adrenoceptors link via the G-protein Gq/G₁₁ to both Ca²⁺ entry and release from stores, but may also activate Rho kinase, which causes calcium sensitization. This study aimed to identify the subtype(s) of α₁-adrenoceptor involved in Rho kinase-mediated responses in both rat aorta and mouse spleen, tissues in which contractions involve multiple subtypes of α₁-adrenoceptor. Tissues were contracted with cumulative concentrations of noradrenaline (NA) in 0.5 log unit increments, before and in the presence of an antagonist or vehicle. Contractions produced by NA in rat aorta are entirely α₁-adrenoceptor mediated as they are competitively blocked by prazosin. The α_1A-adrenoceptor antagonist RS100329 had low potency in rat aorta. The α_1D-adrenoceptor antagonist BMY7378 antagonized contractions in rat aorta in a biphasic manner: low concentrations blocking α_1D-adrenoceptors and high concentrations blocking α_1B-adrenoceptors. The Rho kinase inhibitor fasudil (10 µM) significantly reduced aortic contractions in terms of maximum response, suggesting inhibition of α_1B-adrenoceptor mediated responses. In the mouse spleen, a tissue in which all 3 subtypes of α₁-adrenoceptor are involved in contractions to NA, fasudil (3 µM) significantly reduced both early and late components to the NA contraction, the early component involving α_1B- and α_1D-adrenoceptors, and the late component involving α_1B- and α_1A-adrenoceptors. This suggests that fasudil inhibits α_1B-adrenoceptor mediated responses. It is concluded that α_1D- and α_1B-adrenoceptors interact in rat aorta and α_1D-, α_1A- and α_1B-adrenoceptors interact in the mouse spleen to produce contractions and these interactions suggest that one of the receptors preferentially activates Rho kinase, most likely the α_1B-adrenoceptor.

• Korean Journal of Clinical Laboratory Science
• /
• v.52 no.3
• /
• pp.245-252
• /
• 2020

Macrophage cell death contributes to the formation of plaque, leading to the development of atherosclerosis. The accumulation of triglyceride (TG) is also associated with the pathogenesis of atherosclerosis. A previous study reported that TG induces the cell death of macrophages. This study examined whether the cytoplasmic release of cathepsin B from lysosome is associated with the TG-induced cell death of macrophage. The release of cathepsin B was increased in the TG-treated THP-1 macrophages, but the TG treatment did not affect cathepsin B expression. Furthermore, the inhibition of cathepsin B by its inhibitor, CA-074 Me, partially inhibited the TG-induced cell death of macrophage. TG-triggered macrophage cell death is mediated by the activation of caspase-1, -2, and apoptotic caspases. Therefore, this study investigated whether cathepsin B is implicated in the activation of these caspases. The inhibition of cathepsin B blocked the activation of caspase-7, -8, and -1 but did not affect the activity of caspase-3, -9, and -2. Overall, these results suggest that TG-induced cytoplasmic cathepsin B causes THP-1 macrophage cell death by activating caspase-1, leading to subsequent activation of the extrinsic apoptotic pathway.