• The Korean Journal of Food And Nutrition
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• v.21 no.4
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• pp.436-442
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• 2008

Buckwheat leaves and young parts of the plant are consumed as a vegetable in certain countries. The quality characteristics of Sulgidduk withadded buckwheat vegetable powder(BVP)(0, 0.2, 0.5, 1.0, 1.5% w/w) were assessed in this study. Weobtained the following results: The water contents of Sulgidduk on the first day evidenced no differences according to the ratio of BVP addition, whereas the water contents of Sulgidduk decreased with increasing storage time and increasing amounts of added BVP. As the amount of BVP increased, both the L value(Lightness) and the a value(Redness) decreased, whereas the b value(Yellowness) increased. In terms of the mechanical texture characteristics, the hardness of the Sulgidduk increased with addition of both 0% and 0.5% BVP, with increases in storage time. The springiness of Sulgidduk was reduced as the quantities of BVP increased. We detected no significant differences in the chewiness of Sulgidduk according to the ratio of BVP addition. Also, the chewiness of Sulgidduk increased with BVP additions of 0% and 0.2% with increases in storage time, whereas no differences were detected in the group to which 0.5% BVP was added. The cohesiveness of the Sulgidduk decreased with increases in BVP and storage time. In our sensory evaluation of the color and flavor characteristics, the optimal quality was reported in conjunction with the Sulgidduk to which 1.0% and 1.5% BVP was added(p<0.05), whereas we noted no significant differences in texture and taste(sweetness) according to the ratio of BVP addition. Sulgidduk with 1% of BVP evidenced the best characteristics in our overall sensory evaluation.

• Journal of Korean Medicine Rehabilitation
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• v.23 no.3
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• pp.37-44
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• 2013

Objectives The present study was designed to investigate the effects of bee venom extract pharmacopunctureon (BVP) at 肩井 (GB21) on the changes in regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats, and further to determine the mechanisms. Methods We purchased rats about 300g and prepared diluted BVP with normal saline. And we injected diluted BVP to rats gradually progressed from 0.001 mg/kg to 0.1 mg/kg at corresponding region to GB21. After injection, we measured the changes in rCBF and MABP of rats. In addition, to determine the mechanisms of this changes, we did the same experiments twice more after pretreatment with indomethacin and metylene blue separately. Results BVP significantly increased rCBF but decreased MABP, suggesting that BVP potently may increase rCBF by dilating pial arterial diameter. Furthermore, the increase of BVP-induced rCBF and the decrease of BVP-induced MABP were significantly blocked by pretreatment with cyclooxygenase inhibitor, indomethacin (1 mg/kg, i.p.). But the increase of BVP-induced rCBF and the decrease of BVP-induced MABP were not blocked by pretreatment with guanylate cyclase inhibitor, methylene blue (0.01 mg/kg, i.p.). Conclusions These findings indicate that the action of BVP is mediated by cyclooxygenase. Furthermore these results suggest that BVP can increase rCBF in normal state, as well as improve the stability of rCBF in ischemic state.

• Journal of Pharmacopuncture
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• v.9 no.1
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• pp.121-126
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• 2006

Objective : The purpose of the study was to observe local reactions of BV and BVP skin test, and to compare those between BV and BVP. Methods : We performed BV or BVP Skin test to 42 patients, and then we measured wheal and erytherma on skin test area by digital caliper after 15 minutes. Results : 1. In BV Skin test, the mean size of wheals was $l0.l0{\pm}0.78mm$ and the mean size of erythermas was $29.85{\pm}6.23mm$. 2. In BVP Skin test, the mean size of wheals was $7.05{\pm}3.20mm$ and the mean size of erythermas was $19.58{\pm}7.62mm$. 3. The local reactions of BVP Skin test decreased significantly(P<0.01) than those of BV skin test.

• The Journal of the Korea Contents Association
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• v.17 no.5
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• pp.1-7
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• 2017

Joint Collaborative Team on Video Coding (JCT-VC) of ISO/IEC MPEG and ITU-T developed the HEVC Screen Content Coding (HEVC SCC) standard as the HEVC extension for the screen content video coding. The Intra Block Copy (IBC) is the most effective tool adopted in HEVC SCC and predicts current block from already reconstructed neighboring blocks in the same picture. To reduce the amount of data in BV (Block Vector) to be transmitted, a BV predictor (BVP) is used to generate the BV differences in the IBC BV coding. In this paper, we analyze the current BV prediction process using HEVC reference software SCM-2.0 and SCM-4.0. Based on the analysis results, we propose an improved BVP candidate selection algorithm by adding a search process for adjacent BVs in addition to the existing spatial BVP candidates. Experimental results show that the BD-rate reduction of our proposed improvements ranges from 0.2% to 1%.

• Journal of the Korean Institute of Intelligent Systems
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• v.17 no.2
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• pp.259-264
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• 2007

In this paper, we composed chaos mobile robot by embedding many type of chaos circuit including Arnold Equation and Chua's Equation and proposed method of evaluation of obstacles when it meets or approaches an obstacle while the mobile robot searches an any plane with chaos trajectory and method of concentrating search when it faces target and verified these results. For obstacles avoidance, we developed algorithm that evades an obstacles with chaos trajectory by assuming fixed obstacle, obstacles using VDP model, hidden obstacles using BVP model as obstacles and for searching an object, we developed algorithm of searching with a chaos trajectory by assuming BVP model as an object, verified the results and confirmed reasonability of them.

• Journal of Acupuncture Research
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• v.20 no.2
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• pp.68-76
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• 2003

Objective : In the pain control, Bee Venom Acupuncture therapy is highly effective but cause allergic side-effects frequently. This study was performed to compare Bee Venom(BV) with BV Partner(BVP) in decreasing side-effects of BV. Methods : BV partner(BVP) which dilutes the Morus bombycis Koiduzumi Herbal Acupuncture was developed to decrease the side effects of the Bee Venom. We used D.I.T.I. to verify the effectiveness of BVP in decreasing side-effect of BV. We injected BV to Group I (n=18) at 4 points of body [Fengmen(風門 : B12), Feishu(肺兪 : B13), Fufen(附分 : B41), Pohu(魄戶 : B42)], and BVP to group II (N=18) at the same points. We observed the chages of temperature at beginning, 5 minutes, 1 hour, 1 day, 2days and 7days after injection. Results : The following results were obtained; 1. The difference of temperature had been continued until 2days in BV group, but 1day in BVP group. 2. The difference of temperature was significantly greater than time at 1hour in BV and at 5 minutes in BVP. 3. Other side-effects(the local pain, redness, angioedema and pruritus) were less appeared in BVP than BV group, too.

• Journal of Pharmacopuncture
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• v.11 no.2
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• pp.21-31
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• 2008

Objective This study was performed to investigate whether Bee Venom Pharmacopuncture(BVP) could be a more effective modality than Warm Needling(WN) in relieving pain and symptoms of knee osteoarthritis(OA). Design Prospective, randomized and controlled clinical trial. Setting Single center trial in Korea Patients 49 volunteers with knee OA participated in the study. All the participants were screened through an inclusion and exclusion criteria. 33 participants were completed the clinical trial. Intervention The subjects were randomly assigned to one of two groups. One group received BVP(n=18), while the other group received WN(n=15). Sixteen sessions of BVP or WN were given at the pain region of the problematic knee for 8 weeks. Primary outcome measure is the Korean translation of Western Ontario and McMaster Universities Osteoarthritis Index scores(Korean WOMAC, KWOMAC). Secondary outcome measure is the physical health scores based on the 36-Item Short-Form Health Survey(SF-36) and Patient Global Assessment(PGA). KWOMAC and SF-36 were measured third (baseline, 4 and 8 weeks). PGA was measured twice(4 and 8 weeks). Results BVP group showed significant decrease compared to WN group in pain, function and total scores of KWOMAC according to the Mann-Whitney U-test. In the PGA, BVP group, compared to WN group, showed a significant increase. Conclusions BVP was more effective in relieving pain of knee OA than WN. These findings suggest that BVP is a promising alternative for treating knee OA.

• Journal of Acupuncture Research
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• v.37 no.2
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• pp.123-127
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• 2020

Background: This study was designed using a mouse model of atopic dermatitis [phthalic anhydride (PA)-treated mice], to investigate the anti-inflammatory effect of bee venom pharmacopuncture (BVP) in keratinocytes. Methods: Western blot analysis was performed to investigate inflammation related protein expression of iNOS, COX-2, phospho-ERK (p-ERK), and ERK, in LPS (1 ㎍/mL)-activated keratinocytes, following BVP treatment, and in PA-treated mice, after BVP treatment. Griess reaction was performed to investigate NO concentration. Enzyme-linked immunosorbent assays were used to determine the concentrations of interleukin (IL)-4+, IL-17A+, IL-13 and IL-4 in PA-treated mice after BVP treatment. In addition, monocyte, macrophage, neutrophil, and eosinophil counts were measured to observe the changes in white blood cell infiltration. Results: The keratinocytes of the BVP-treated group showed a decreased expression of iNOS, COX-2, ERK at 5 OX-2, ERK E, and p-ERK at 1, 2 and 5 RKRK ERK ERK, and a dose-dependent decrease in NO concentration at 2 and 5 ntrationof s. In the BVP-treated groups (0.1 μ.1-trea μ.1-treated gr), PA-treated mice showed recovery after 4 weeks which was dose-dependent, showing a significant decrease in clinical scores for AD, and a decreased concentration of IL-13 and IL-4 with BV treatment. There was a dose-dependent decrease in the infiltration of eosinophils, neutrophils, monocytes, macrophages, and a decreased thickness of the epidermis due to inflammation, and decreased expressions of iNOS, COX-2, p-ERK, ERK, especially in the 0.1 μ0/mL BVP-treated group, Conclusion: These results suggest that BVP may be an effective alternative treatment for atopic dermatitis.

• The Transactions of the Korea Information Processing Society
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• v.3 no.4
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• pp.877-882
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• 1996

The effects of periodic and chaotic behaviour in the Bonhoeffer-Van der Pol (BVP) oscillation of the nerve membrane driven by a periodic stimulating current A1 coswtare investigated through hardware implementation.For hardware implementation of the BVP model. real element values were escaled with computer simulation results to determine the parameter real value.As the parameter A1 varied in the range 0 to 1.3, the BVP model showed an ordinary and reversed period-doubling cascade and a chaotic state. At the low driving amplitude ofa1 the period-doubling showed and at the high driving amplitude of A1 the chaotic state occured. To analyse the BVP model for chaotic behaviour Phase Plane, Time series are used to verify that properties.

• Journal of Acupuncture Research
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• v.36 no.4
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• pp.220-229
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• 2019

Background: The therapeutic potential of Bee Venom Pharmacopuncture (BVP) on acute ischemic cerebral infraction was determined in mice in vivo and in vitro. Methods: Analysis of acute ischemic cerebral infraction was performed using 7 week old male ICR mice (n = 20) and microglial BV-2 cells. Bee venom ($5{\mu}g/kg$) was injected into the caudal vein of middle cerebral artery occlusion (MCAo) mice (1 hour after reperfusion, 3 hours after MCAo probe insertion), and also used to treat LPS-stimulated microglial BV-2 cells (1, 2, $5{\mu}g/mL$). Markers of inflammation were monitored. Results: NO declined statistically significantly in BVP treated MCAo mice compared to the untreated MCAo group (p < 0.05). Compared to the MCAo group, the BVP-treated MCAo group showed a decreased production volume of malondialdehyde, but an increased glutathione/oxidized glutathione ratio. Compared to the untreated MCAo group, the BVP treated MCAo group showed a statistically significant decline in TNF and $IL-1{\beta}$ levels (p < 0.05). BVP inhibited the levels of p65, p50, $p-I{\kappa}B-{\alpha}$, and levels of p-ERK1/2, p-JNK2, p-P38 declined. Conclusion: BVP is effective at dampening the inflammatory response in vivo and in vitro and may supplement rt-PA treatment.