• Molecules and Cells
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• 제37권2호
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• pp.126-132
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• 2014

As a tumor suppressor homologue during mitosis, Chk2 is involved in replication checkpoints, DNA repair, and cell cycle arrest, although its functions during mouse oocyte meiosis and early embryo development remain uncertain. We investigated the functions of Chk2 during mouse oocyte maturation and early embryo development. Chk2 exhibited a dynamic localization pattern; Chk2 expression was restricted to germinal vesicles at the germinal vesicle (GV) stage, was associated with centromeres at pro-metaphase I (Pro-MI), and localized to spindle poles at metaphase I (MI). Disrupting Chk2 activity resulted in cell cycle progression defects. First, inhibitor-treated oocytes were arrested at the GV stage and failed to undergo germinal vesicle breakdown (GVBD); this could be rescued after Chk2 inhibition release. Second, Chk2 inhibition after oocyte GVBD caused MI arrest. Third, the first cleavage of early embryo development was disrupted by Chk2 inhibition. Additionally, in inhibitor-treated oocytes, checkpoint protein Bub3 expression was consistently localized at centromeres at the MI stage, which indicated that the spindle assembly checkpoint (SAC) was activated. Moreover, disrupting Chk2 activity in oocytes caused severe chromosome misalignments and spindle disruption. In inhibitor-treated oocytes, centrosome protein ${\gamma}$-tubulin and Polo-like kinase 1 (Plk1) were dissociated from spindle poles. These results indicated that Chk2 regulated cell cycle progression and spindle assembly during mouse oocyte maturation and early embryo development.

• Nuclear Engineering and Technology
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• 제23권1호
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• pp.56-65
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• 1991

RELAP5/MOD2 Cycle 36.04코드를 이용하여 LOFT대형냉각재 상실사고 모사실험 L2-3를 계산함으로써 코드의 대형냉각재상실사고에 관련된 열수력현상 예측능력을 평가하였다. 기본계산에서 원자로 압력용기는 이중노심유로와 분리강수관 모델로 모사되었다. 기본계산의 결과 계통의 전반적인 수력학적 거동과 감압기간동안 노심 고출력 부위에서의 열적 거동은 비교적 타당하게 예측되었다. 한편 과냉각-이상유동의 천이 기간동안 임계유량모델, 고질량유속에서의 임계열유속 상관식, 감압기간중의 재접수(Blowdown Rewet)의 판정기준등 코드의 모델/상관식의 부분적 결함이 발견되었다. 이 결함들에 의해 냉각재 재고량이 과대 평가되어 재환수기간의 노심의 열적거동 예측의 정확도가 감소되었다. RELAP5/MOD2 Cycle 36.04로 부터 개선된 코드를 사용한 계산 결과 재접수 현상의 예측 정확도를 개선할 수 있었다.

• 한국산업융합학회 논문집
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• 제14권2호
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• pp.59-65
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• 2011

$CO_2$ Welding which uses $CO_2$ instead of inert gas is most widely used in industrial sites. Welding rod for $CO_2$ Welding is roughly divided into solid wire and flux cored wire. $CO_2$ Welding has higher efficiency than any other welding methods, and also economic and speedy to handle, that's why is used frequently for welding general structures. As most of studies about $CO_2$ Welding are focused on metallurgical changes of successful joints, they developed theories about the change of configuration on weld parts. This study is especially focused on not only the change of configuration on weld parts, but also the change of the penetrating depth through changing the position of welding torch. For inspection, applied AWS A5.20 E70-1 among welding wires and fixed moving angles of torch, but controled the values of voltage and the position of welding. Also Automatic Feed Mechanism is used for exact movement of material, specimen is a piece of steel for general structures. By measuring and analyzing the configuration of sliced section and the values of welding leg length and welding throat after welding, the outcome about the changes turned out.

• Journal of the Korean Wood Science and Technology
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• 제6권1호
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• pp.8-14
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• 1978

In order to determine the feeding value of t:1e waste wood of Lentinus eddodes, the waste wood was milled and treated with $Ca(OH)_2$ and cellulase, then raw waste wood and the treated waste wood were fed to broiler chicken and Korean native goates. The results obtained were as follows; 1. The chemical composition of the waste wood was c. protein 2.26%. c. fat 2.57%. c. fiber 44.60 and c. ash 5.58%. No differences were detected between the raw waste wood and $Ca(OH)_2$ or cellulase treated waste wood in chemical composition. 2. In amino acid composition. no cystine and methionine was showed, but trace amount of Vitamin A, $B_1$, and $B_2$, and cholin chloride were detected. 3. Trichoderma viride SANK. No. 16374 was used to decompose the cellulose. 4. In broiler performance, when waste wood meal was subsituted for 5% wheat bran, no adverse effect was showed on weight gain, feed in take and feed efficiency. But $Ca(OH)_2$ and cellulase treated waste wood meal could be subsituted for 8% wheat bran. 5. In Korean native goat performance, feeding waste wood meal subsituted by 50% various bran (25% defatted rice bran and 25% barley bran) had no adverse effect on growth and feed efficiency. 6. Considering the above results, though the waste wood meal could be replaced to part of various bran, there was a bottle-neck to process the waste wood. The waste wood of Lentinus edodes was little feeding value on bed of ruminant.

• 한국통신학회논문지
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• 제27권1B호
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• pp.24-33
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• 2002

비동기 W-CDMA를 위한 셀 탐색 방법은 슬롯 동기 과정(stage 1), 그룹 확인 및 프레임 동기 과정(stage 2), 긴 코드 동기 과정(stage 3)으로 구성되어있다. 특히 이동국에 전력이 처음 들어왔을 때 수행되는 셀 탐색을 초기 셀 탐색이라 한다. 초기 셀 탐색에서는 이동국의 초기 주파수 오차와 시간 오차에 의해 성능이 저하된다. 본 논문에서는 이러한 동기 오류 중 초기에 클럭 발생기에 의해 유발되는 시간 오차를 보상해주기 위해 시간 동기 블록을 적용한 초기 셀 탐색 방법을 제안한다. 제안된 방식에서는 시간 동기 블록이 슬롯 동기 과정에서 할당된 슬롯 시작점을 기준으로 동기 추적 과정을 수행하므로 stage 2와 stage 3에서의 시간 오차를 보상하게 된다. 제안된 초기 셀 탐색 방법을 사용할 경우, 시스템의 시간 오차가 ${\pm}T_c$/2일 때, 기존 방식보다 최대 1.5dB의 성능 향상을 얻을 수 있었다.

• Nuclear Engineering and Technology
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• 제22권1호
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• pp.12-19
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• 1990

1981년 6월 9일 고리 1호기 원자력발전소에서 발생한 외부 전원 상실사고 자료를 근거로 RELAP5/MOD2코드모델 평가를 하였다. 계산된 주요 열ㆍ수력학 변수를 실측자료와 비교 분석하였으며 증기발생기의 Nodalization 민감도 분석이 수행되었다. 계산된 열ㆍ수력학 변수는 실측치와 비교적 잘 일치하고 있으며, 이러한 유형의 사고 분석에 RELAP5/MOD2가 적합하다는 것을 보였다. 그러나 가압기 압력과 수위변동에서는 상당한 차이를 보였으며 높게 계산되었다. 이러한 사실은 RELAP5의 수직관에서의 층류 열전달 모델에 기인하는 것으로 해당모델의 개선을 요하고 있다는 것을 알았다. 그리고 증기발생기의 Nodalization 연구를 통하여 수위변동을 잘 예측하기 1위해서는 증기발생기 증기 Dome와 Downcomer사이에 압력을 전달시켜주는 유로를 모델링 하여야 한다는 것을 알았다.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1996년도 춘계학술발표회논문집(2)
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• pp.513-518
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• 1996

This report presents a demonstration of application of realistic evaluation methodology to a posturated cold leg large break LOCA in a Westinghouse three-loop pressurized water reactor with 17$\times$17 fuel. The new method of this analysis can be divided into three distinct step: 1) Best Estimate Code Validation and Uncertainty Quantification 2) Realistic LOCA Calculation 3) Limiting Value LOCA Calculation and Uncertainty Combination RELAP5/MOD3/K ［1］, which was improved from RELAP5/MOD3.1, and CONTEMPT4/MOD5 code were used as a best estimate thermal-hydraulic model for realistic LOCA calculation. The code uncertainties which will be determined in step 1) were quantified already in previous study ［2］, and thus the step 2) and 3) for plant application were presented in this paper. The application uncertainty parameters are divided into two categories, i.e. plant system parameters and fuel statistical parameters. Single parameter sensitivity calculations were performed to select system parameters which would be set at their limiting value in Limiting Value Approach (LVA) calculation. Single run of LVA calculation generated 27 PCT data according to the various combinations of fuel parameters and these data provided input to response surface generation. The probability distribution function was generated from Monte Carlo sampling of a response surface and the upper 95$^{th}$ percentile PCT was determined. Break spectrum analysis was also made to determine the critical break size. The results show that sufficient LOCA margin can be obtained for the demonstration NPP.

• 한국구조물진단유지관리공학회 논문집
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• 제25권2호
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• pp.35-42
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• 2021

본 연구에서는 NFPA 13을 참조하여 구조물 2층을 구현한 강재지그를 제작하였으며, 그루브 조인트의 배관연결재가 적용된 배관계통을 구성하고 정적 반복가력에 의한 지진모사실험을 수행하였다. 지진모사실험은 엑츄에이터로 건축물 내진설계기준의 최대허용 층간변위에 대한 반복가력실험을 수행하였다. 지진하중 발생 시 입상배관의 구조물에 대한 변형 또는 구조부재간의 상대변위에 의한 변위지배적인 거동에 따른 배관계통과 주요 배관요소의 지진거동을 분석하였다. 배관계통의 변형각은 기존의 센서를 이용하여 측정하기가 어려우므로 이미지측정시스템을 적용하였다.

• 한국기계가공학회지
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• 제14권2호
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• pp.38-43
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• 2015

Tungsten inert gas (TIG) welding is commonly used in industries that require airtightness, watertightness, oiltightness, and precision. It is a non-consumable welding method that is commonly used for the welding of non-ferrous metals, but it can be used to weld most metals. The methods of TIG welding can be divided into three types. The first, manual welding is done directly on the metal by a welder with a torch. The second, semi-automatic welding, gets help from a material supplying machine, but it is conducted by a welder. Lastly, automated welding is conducted fully by a machine during its process and operation. Depending on the selection of electrode, the amount of heat that is applied to the base material and the electrode rod changes and makes the shape of welded parts different. A direct-current positive electrode was used for this study. Through the change of shielding gas type on a structural steel (SS-400) that is commonly used in industry, the composition and shape changes in welded parts were detected after welding. The heat-affected area, hardness value, and tensile strength were also identified through hardness testing and tensile testing. In this study, it was found that the higher hardness value of the heat-affected is, the weaker the tensile strength becomes.

• 한국지진공학회논문집
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• 제21권2호
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• pp.87-93
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• 2017

Many studies are conducted in several fields for fragility analysis of structures or elements which is a probabilistic seismic safety analysis in consideration with uncertainty of seismic loading. It is hard to directly conduct fragility analysis for an infrastructure with social importance due to its size. Therefore, a fragility analysis for an infrastructure mainly conducted in element level or conducted with scaled model built in accordance with similarity law. In this article, fragility analysis for prototype and scaled model of reinforced concrete column was conducted with numerical models which had been updated by the results of shaking table test and pseudo dynamic test. As a result, response stress from the numerical analysis result of prototype model was higher than that from scaled model due to different stiffness ratios between steel and concrete. However, the probability of failure for scaled model was higher than that for prototype model because failure criteria for scaled model was down due to similarity law. Also it was evaluated that probability of failure by using log normal standard deviation of response stresses by spectrum matched accelerograms was more reliable than probability of failure by using existing coefficient of variation normally used.