• Proceedings of the Korea Information Processing Society Conference
• /
• 2010.04a
• /
• pp.977-980
• /
• 2010

기업내부에 존재하는 비즈니스 룰은 정형화되고 집중화된 하나의 시스템으로 구축되어 있는 것이 아니라 여러 서브시스템이나 실무자의 경험속에 산재되어 존재한다. 산재되어 존재하는 비즈니스 룰을 정형화된 형태로 집중관리가 가능하도록 구축한 도구가 BRE(Business Rule Engine)이다. BRE는 비즈니스 룰 관리를 빠르고 용이하게 하여, 기업의 경쟁력 향상에 매우 효과적인 기여를 한다. 하지만 BRE도입시 고려해야 할 품질특성을 판단할 뚜렷한 기준을 가지고 있지 못 하기 때문에 고가의 솔루션인 BRE도입에 많은 어려움을 겪고 있다. 본 연구에서는 국제 표준 ISO/IEC 9126를 기반으로 BRE가 갖추어야 할 품질특성을 정의하고 BRE 도입시 고려해야 할 품질특성을 판단할 수 있는 판별분석기법을 통해 BRE를 명확히 이해할 수 있는 품질평가모델을 제시함으로서 이러한 문제를 해결하고자 한다. 또한 본 연구의 결과는 실제 구축된 BRE 사례들에 대해 판별분석기법을 통해 검증하며, 검증된 품질평가모델의 활용방안을 제시한다.

• Proceedings of the Korea Inteligent Information System Society Conference
• /
• 2004.11a
• /
• pp.369-374
• /
• 2004

기업 내부에 존재하는 비즈니스 룰은 정형화되고 집중화된 하나의 시스템으로 구축되어 있는 것이 아니라 여러 서브시스템이나 실무자들의 경험 속에 산재되어 존재한다. 산재되어 존재하는 비즈니스 룰을 정형화된 형태로 집중관리가 가능하도록 구축한 도구가 BRE(Business Rule Engine)이다. BRE는 비즈니스 룰 관리를 빠르고 용이하게 하여, 기업의 경쟁력 향상에 매우 효과적인 기여를 한다. 본 연구에서는 BRE도입의 적합성 여부를 평가할 수 있는 모델을 제시한다. 본 연구의 결과를 활용하면 기업은 용이하게 BRE도입 여부를 판단할 수 있어 기업의 경쟁력을 향상시킬 수 있을 것이다.

• Journal of Intelligence and Information Systems
• /
• v.11 no.3
• /
• pp.103-115
• /
• 2005

For today's enterprises to survive in the current rapidly changing business environments, it is imperative to make quick and successful decisions to various challenges. In making important business decisions, if enterprises utilize business rules and knowledge, properly and promptly, they may effectively reduce the chance of failures. However, in most of today's information systems, these rules and knowledge are not managed in centralized and systemic manner. They disperse over entire enterprises' information systems, and sometimes reside in the heads or memos of enterprises' employees. BRE (Business Rule Engines) is a solution that systematically and centrally manages these business knowledge and rules of an enterprise. With BREs, any business user is able to store, edit, retrieve and utilize business rules and knowledge in centralized repository, without IT development skills. And with BRE, enterprises could improve business intelligence and attain strategic advantages over other enterprises. However, since there is no clear criteria for BRE introductions, it is not easy to decide whether or not to introduce the expensive BRE solution to an enterprise. In this research we propose a decision model for BRE introduction. Using this model, business analysts considering BRE introduction, readily make decisions on BRE introduction.

• The Journal of Internal Korean Medicine
• /
• v.21 no.5
• /
• pp.781-789
• /
• 2000

Objective : The purpose of these research was to investigate effects of water extract of Bistortae Rhizoma(BRE) on the hemostasia, anti-inflammatory action and central nervous system. Methods : we used mice and rats administered with the extract of the above herbs. Results : BRE decreased the permeability of evans blue into peritoneal cavity and cotton pellet granuloma formation. BRE did not decrease the acetic acid induced writhing syndrome and the histamine induced mouse paw edema. BRE inhibited the pentylenetetrazole and the strychnine induced convulsion. BRE shortened the bleeding time and plasma prtrombin time. BRE did not affect on the proliferation of Balb/c 3T3 cells. Conclusions : these results suggest that the effects of BRE are the hemostasia, anti-inflammatory action, and mild depressant activity of central nervous system.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2006.11a
• /
• pp.487-490
• /
• 2006

단일의 BRE를 사용하는 비즈니스 롤 시스템에 새로운 룰이 추가 또는 수정될 경우, 기존의 비즈니스 룰과 의미적인 충돌이 발생할 수 있으며, 이는 잘못된 비즈니스 수행결과를 초래하는 원인이 된다. 이를 위해 비즈니스 룰 시스템은 내부적으로 발생하는 비즈니스 룰 간의 충돌을 검출하고 해결할 수 있는 기능을 제공한다. 그러나 서로 다르게 구현된 다수의 BRE를 이용하는 분산 비즈니스 룰 시스템에서는 하나의 BRE에 추가된 새로운 비즈니스 룰이 다른 BRE의 룰과 충돌이 발생하는지 여부를 자동적으로 확인할 수 있는 방법이 제공되지 않아서, 사용자가 직접 모든 BRE에서 룰의 충돌 여부를 확인해야 하는 어려움을 가지고 있다. 기존의 분산 비즈니스 룰 시스템에 관한 연구에서도 서로 다른 BRE들을 분산 배치하고 비즈니스 룰을 실행하는 방법에 대한 연구만을 수행하였을 뿐, 분산된 비즈니스 룰 간의 충돌을 해결하는 것에 대한 연구는 미흡한 실정이다. 본 논문은 이러한 분산 비즈니스 룰 시스템에서 비즈니스 룰의 추가 및 변경 발생 시, 룰 간의 충돌을 검출하고 해결하기 위하여 기존 연구의 한계점을 분석하고 새로운 시스템 요구사항들을 도출하였다. 이를 기반으로 기존에 제시된 비즈니스 룰 브로커 구조를 확장, 보완한 분산 비즈니스 룰 충돌 검출 시스템의 아키텍처를 제안하고 이를 설계하였다.

• The Journal of the Korea Contents Association
• /
• v.15 no.9
• /
• pp.599-605
• /
• 2015

This study was conducted to evaluate suppressive effects of black rice aleurone layer extract (BRE) on body fat, serum lipid, and hormone levels in ovariectomized rats. The rats were divided into five groups (n=8/group): sham operated group (S); ovariectomized control group (OVX); ovariectomized group treated with isoflavone 10 mg/kg B.W. (IF); ovariectomized group treated with BRE 30 or 90mg/kg B.W. (BRE-30 or -90). High fat diet (45% calories from fat) was fed to all rats for 12 weeks. Body weight gain, body fat weight, and adiposity index increased in the OVX group, but they significantly decreased in IF or BRE supplementation. Serum triacylglycerol and leptin levels decreased in BRE groups while serum adiponectin level significantly increased compared to that of the OVX group. Hepatic total lipid, triglyceride, and cholesterol levels increased in the OVX group, but they decreased in BRE supplementation (p>0.05). These data suggest that black rice aleurone layer may be a useful food source to decrease obesity and its related diseases by modulating lipid metabolism in estrogen-deficiency model.

• Journal of Home Health Care Nursing
• /
• v.30 no.2
• /
• pp.202-215
• /
• 2023

Purpose: This study attempted to determine the factors related to behaviors of reducing exposure to endocrine disrupting chemicals (BRE to EDCs) in pregnancy, based on the PRECEDE model. Methods: A cross-sectional survey was conducted with participants (N=239) who met the medical records and eligibility criteria from the Women's Hospital and Public Health Center. Data were collected using a specially-designed questionnaire based on the PRECEDE model and included BRE to EDCs predisposing factors, reinforcing factors, and enabling factors. The data were analyzed using the chi-square test, independent t-test, one way ANOVA, Pearson's correlation coefficients and a hierarchical multiple regression analysis. Results: In Model I it was found that participation in prenatal education influenced the BRE to EDCs significantly; and a regression showed that the determinant variables accounted for 3.4%. In Model II, the predisposing factors of perceived barriers of BRE to EDCs and environmental self-efficacy were added. It was shown that they significantly influenced BRE to EDCs in the order named, and a regression revealed that increases in the determinant variables accounted for 22.5%. In Model III, to which enabling factors were added, the information acquisition experience of BRE to EDCs interacted significantly with BRE to EDCs and a regression showed an increase in the determinant variables accounting for 25.3%. Conclusion: The results of this study, the content of endocrine disruptors must be included in the prenatal care education program for pregnant women, and it should be composed of contents that can reduce the perceived obstacle to BRE to EDCs, enhance the environmental self-efficacy, and provide the information in regard to reducing exposure to EDCs.

• Journal of Microbiology and Biotechnology
• /
• v.27 no.3
• /
• pp.542-551
• /
• 2017

Small phytochemicals have been successfully adopted as antibacterial chemotherapies and are being increasingly viewed as potential antibiofilm agents. Some of these molecules are known to repress biofilm and toxin production by certain bacterial and yeast pathogens, but information is lacking with regard to the genes allied with biofilm formation. The present study was performed to investigate the inhibitory effect of burdock root extract (BRE) and of chlorogenic acid (CGA; a component of BRE) on clinical isolates of Klebsiella pneumoniae. BRE and CGA exhibited significant antibiofilm activity against K. pneumoniae without inflicting any harm to its planktonic counterparts. In vitro assays supported the ${\beta}$-lactamase inhibitory effect of CGA and BRE while in silico docking showed that CGA bound strongly with the active sites of sulfhydryl-variable-1 ${\beta}$-lactamase. Furthermore, the mRNA transcript levels of two biofilm-associated genes (type 3 fimbriae mrkD and trehalose-6-phosphate hydrolase treC) were significantly downregulated in CGA- and BRE-treated samples. In addition, CGA inhibited biofilm formation by Escherichia coli and Candida albicans without affecting their planktonic cell growth. These findings show that BRE and its component CGA have potential use in antibiofilm strategies against persistent K. pneumoniae infections.

• Clinical and Experimental Pediatrics
• /
• v.55 no.10
• /
• pp.383-387
• /
• 2012

Purpose: Although benign rolandic epilepsy (BRE) is a benign condition, it may be associated with a spectrum of behavioral, psychiatric, and cognitive disorders. This study aimed to assess the cognitive and other neuropsychological profiles of children with BRE. Methods: In total, 23 children with BRE were consecutively recruited. All children underwent sleep electroencephalography (EEG) and were assessed on a battery of comprehensive neuropsychological tests including the Korean versions of the Wechsler intelligence scale for children III, frontal executive neuropsychological test, rey complex figure test, Wisconsin card sorting test, attention deficit diagnostic scale, and child behavior checklist scale. Results: The study subjects included 13 boys and 10 girls aged $9.0{\pm}1.6$ years. Our subjects showed an average monthly seizure frequency of $0.9{\pm}0.7$, and a majority of them had focal seizures (70%). The spike index (frequency/min) was $4.1{\pm}5.3$ (right) and $13.1{\pm}15.9$ (left). Of the 23 subjects, 9 showed frequent spikes (>10/min) on the EEG. The subjects had normal cognitive and frontal executive functions, memory, and other neuropsychological sub-domain scores, even though 8 children (35%) showed some evidence of learning difficulties, attention deficits, and aggressive behavior. Conclusion: Our data have limited predictive value; however, these data demonstrate that although BRE appears to be benign at the onset, children with BRE might develop cognitive, behavioral, and other psychiatric disorders during the active phase of epilepsy, and these problems may even outlast the BRE. Therefore, we recommend scrupulous follow-up for children with BRE.

• Journal of Biomedical Engineering Research
• /
• v.35 no.4
• /
• pp.95-98
• /
• 2014

The baroreflex is one kind of homeostatic mechanisms to regulate acute blood pressure (BP) changes by controlling heartbeat interval (HBI). To quantify the effect of baroreflex, we suggested a new approach of analyzing Granger causality between systolic BP (SBP) and HBI. The index defined as baroreflex effectiveness (BRE) was generated by the hypothesis that more effectual baroreflex would be related to more effective Granger causal influence of SBP on HBI. Six obstructive sleep apnea (OSA) patients (apnea-hypopnea index, AHI ${\geq}5$ events/hr) and six normal subjects participated in the study. Their SBP and HBI during nocturnal sleep were obtained from a non-invasive continuous BP measurement device. While the BRE ($mean{\pm}SD$) of normal subjects was $47.0{\pm}4.0%$, OSA patients exhibited the BRE of $34.0{\pm}3.8%$. The impaired baroreflex function of OSA patients can be explained by the physiological mechanism associated with recurrent hypoxic episodes during sleep. Thus, the significantly lower BRE in OSA patients verified the availability of Granger causality analysis to evaluate baroreflex during sleep. Furthermore, the range of BRE obtained from normal subjects was not overlapped with that obtained from OSA patients. It suggests the potential of BRE as a new helpful tool for diagnosing OSA.