• 성인간호학회지
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• 제25권4호
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• pp.473-482
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• 2013

Purpose: The purpose of this study was to investigate the effects of a structured preoperative instruction upon anxiety and postoperative self-care compliance. Methods: A randomized control group pre-post design was used. Sixty subjects undergoing cataract surgery were randomly assigned to one of two groups. The instruction consisted of cataract surgery procedure, sensory information, deep breathing, use of eye drop, and post op self-care regimen and was provided to the experimental group with control group receiving an usual treatment. State anxiety NRS, pulse, BP, and self-care compliance scale developed by Cho & Rho were used. Data were collected at two time periods: on the day of surgery in the clinic and prior to anesthesia in the operating room. The postoperative self-care compliance scores were measured at their second visits to the hospital after surgery. Data were analyzed using Kolmogorov Smirnov test, t-test, and Mann-Whitney U test. Results: There were significant differences between the two groups in the postoperative state anxiety (t=-3.57, p=.001) and the postoperative self-care compliance score (t=3.92, p<.001). There were no significant difference between the two groups in the postoperative blood pressure and pulse rate. Conclusion: The results of this study suggest that the structured preoperative instruction could be a nursing intervention for cataract surgery patients.

• Journal of Korean Biological Nursing Science
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• 제11권1호
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• pp.68-76
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• 2009

Purpose: The purpose of this study was to evaluate the hemodynamic changes in degree and duration that occur during Valsalva maneuver (VM). Furthermore, we wanted to investigate the patterns and mechanisms of physiological hemodynamic control. Method: Thirty six healthy college students were recruited from Y university. Each participant was provided with written informed consent. Blood pressure (BP), heart rate (HR), cardiac output (CO) were continuously recorded using the Finometer. Result: During the phase I of VM, means of systolic and diastolic pressures were increased by 32.15% and 38.28%, respectively, compared with basal values. HR and CO were decreased by 9.91% and 13.01%, respectively. Immediately after the maneuver (phase III), systolic and diastolic pressures were decreased by 5.05% and 6.24%, respectively, compared with those obtained in the phase II. HR and CO were elevated by 13.33% and 11.93%, respectively, compared to the levels of earlier phases. BPs were represented with overshoot in the phase IV, and recovered by baseline values about 20 sec after VM. Conclusion: These results demonstrated that hemodynamic changes are variable in the event of VM even in healthy humans. It will be valuable to accumulate more quantitative hemodynamic information in special populations such as the elderly and the patients with cardiovascular problems.

• 약학회지
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• 제56권5호
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• pp.309-313
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• 2012

Antiobesity, hypotriglyceridemic and antihypertensive activities of isoflavone-free peptide mixture (black soybean peptide, BSP) were reported in our previous experiments. In the present study, angiotensin converting enzyme inhibitory (ACEi) activity was decreased in the aorta tissues of spontaneously hypertensive rats (SHRs) treated with BSP (1% in drink water) for 4 weeks, but not in serum. BSP administration significantly decreased ACE activity by 17.5% (from $33.2{\pm}4.5$ to $27.4{\pm}1.96$ mUnit/mg, p=0.0013) in aorta tissue hydrolysate. BSP treatment also decreased significantly mean blood pressure (BP) (from $213.0{\pm}16.96$ to $184.0{\pm}6.53$ mmHg, p<0.0001) as expected. These results indicate that BSP has antihypertensive activity as well as ACEi activity.

• 대한약침학회지
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• 제18권1호
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• pp.7-18
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• 2015

Objectives: Loranthus ferrugineus (L. ferrugineus) from Loranthaceae, a mistletoe, is a medicinal herb used for a variety of human ailments. Traditionally, decoctions of this parasitic shrub have been mainly used to treat high blood pressure (BP) and gastrointestinal complaints; usage which is supported by experimental based pharmacological investigations. Nonetheless, there is still limited data available evaluating this plant's traditions, and few studies have been scientifically translated toward evidence based phytomedicine. We therefore provide a concise review of the currently available L. ferrugineus literature and discuss potential directions for future areas of investigation. Methods: We surveyed available literature covering ethnopharmacological usage of L. ferrugineus and discussed relevant findings, including important future directions and shortcomings for the medicinal values of this parasitic shrub. Results: Evidence based pharmacological approaches significantly covered the medicinal application of L. ferrugineus for hypertension and gastrointestinal complaint management, with a particular focus on the active hydrophilic extract of this herb. Conclusion: Understanding the sites of action of this plant and its beneficial effects will provide justification for its use in old traditional treatments, and potentially lead to the development of therapies. Other medicinal applicative areas of this parasitic shrub, such as wound healing, gerontological effects, and antiviral and anticancer activities, are yet to be researched.

• 근관절건강학회지
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• 제16권2호
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• pp.116-124
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• 2009

Purpose: The purpose of this study was to examine the effects of a Tai Chi exercise program on physical function and physiological variables in patients with degenerative arthritis. Methods: The study utilized a nonequivalent control group with pretest-posttest design. Data collection was done with the elders from two welfare institutions in C-city between July I and September 22, 2007. The participants were assigned either to an experimental group (n=24) or to a control group (n=22). The experimental group participated in Tai Chi exercise for 60 minutes per session, twice a week for 12 weeks and the control group received the education about arthritis for 3 weeks. Results: Except for $VO_2max$, weight, and body fat rate, the elders in the experimental group showed significant improvement in physical function (grip strength, flexibility, balance), and physiological variables (BP) compared to the control group. Conclusion: The results suggest that Tai Chi exercise would partially improve physical function, and physiological variables. Further studies are needed to determine the effects on physical fitness and physiological variables after Tai Chi exercise in this population.

• International Journal of Computer Science & Network Security
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• 제23권7호
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• pp.171-185
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• 2023

The cardiovascular syndrome is the dominant reason for death and the number of deaths due to this syndrome has greatly increased recently. Regular cardiac monitoring is crucial in controlling heart parameters, particularly for initial examination and precautions. The quantity of cardiac patients is rising each day and it would increase the load of work for doctors/nurses in handling the patients' situation. Hence, it needed a solution that might benefit doctors/nurses in monitoring the improvement of the health condition of patients in real-time and likewise assure decreasing medical treatment expenses. Regular heart monitoring via wireless body area networks (WBANs) including implantable and wearable medical devices is contemplated as a life-changing technique for medical assistance. This article focuses on the latest development in wearable and implantable devices for cardiovascular monitoring. First, we go through the wearable devices for the electrocardiogram (ECG) monitoring. Then, we reviewed the implantable devices for Blood Pressure (BP) monitoring. Subsequently, the evaluation of leading wearable and implantable sensors for heart monitoring mentioned over the previous six years, the current article provides uncertain direction concerning the description of diagnostic effectiveness, thus intending on making discussion in the technical communal to permit aimed at the formation of well-designed techniques. The article is concluded by debating several technical issues in wearable and implantable technology and their possible potential solutions for conquering these challenges.

• 대한의생명과학회지
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• 제14권4호
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• pp.219-223
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• 2008

The present study was designed to clarify whether scuba diving at 5 meters of seawater influences cerebral hemodynamics, hematological and biochemical variables. Twenty healthy young men well trained scuba diving participated in this study. The blood flow velocity in the right and left middle cerebral arteries (L-MCAV and R-MCAV), blood pressure (BP), heart rate (HR), CBC and differential count, prothrombin time (PT), activated partial thromboplastin time (aPTT), biochemical variables, D-dimer and interleukin-8 (IL-8) levels were determined before, immediately after scuba diving for 30 min, and after 30 min of rest (Pre-scuba, Scuba and R-30m, respectively). L-MCAV and R-MCAV tended to increase, but the only significant increase was in L-MCAV in Scuba. SBP and HR significantly declined in R-30m compared with those of Pre-scuba and the Scuba. IL-8 levels were elevated in Scuba and R-30m compared with that of Pre-scuba. In Scuba and R-30m, hematological variables except PT and biochemical parameters excluding glucose and lactic acid did not significantly changed in comparison with those of Pre-scuba. PT level at Scuba and glucose level at R-30m significantly declined in Scuba, while lactate level at R-30m increased compared with each in Pre-scuba. However, PT level at Scuba was within a normal range. These results suggest that scuba diving at 5 m of seawater for 30 min has no adverse effects, is safe and useful for improving health. However, further study must be performed to clarify the mechanism of elevated IL-8 level following scuba diving.

• Journal of Nutrition and Health
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• 제33권8호
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• pp.873-881
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• 2000

Recent research reported health risks associate with high carbohydrates diets. Objectives of this study were to evaluate in a cross-sectional study if high carbohydrate diet is associated with coronary heart disease(CHD) risk factors: examined blood concnetration of triglyceride(TG), total cholesterol, high density lipoprotein cholesterol(HDL-C), plasma glucose, systolic blood pressure(BP), body mas index(BMI), wasit-hip ratio(WHR) and waist-stature ratio(WSR). Using the most recent US National Health and Nutrition Examination Survey(IIINHANES III) data, the nationally representative US population (3772 men, 4095 women of 25-64 years of age) was divided into low vs. high carbohydrate diet groups(below 40% vs. above 60% energy intake from cab carbohydrates) and compared by the CHD risk factors. Triglyceride was higher(p<0.001) in the high carbohydrate group, whereas high density-lipoprotein cholesterol(HDL-C)was lower(p<0.01) in the high carbohydrate diet group. In plasma glucose, there was no significant differences between high carbohydrate diet and low carbohydrate diet. In adiposity(BMI, WHR and WSR), it also showed no significant differences, After adjustment for age, ethnicity, alcohol and smoking in upper 60%-carbohydrate diet, Odds Ratio of TG and HDL-C were 1.42 and 1.23 in men and 1.22 and 1.17 in women. 50-60% carbohydrate diet was associated with decreased risk of CHD. Dietary guidelines for Koreans recommend 60-70% of total energy from carbohydrate, as Koreans traditionally consumed high carbohydrate diets. In a cross-sectional population of adults, diets containing 55-60% energy from carbohydrate were suggested as a dietary guideline of carbohydrate intake for Koreans. (Korean J Nutrition 33(8) : 873-881, 2000)

• 대한약침학회지
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• 제22권3호
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• pp.147-153
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• 2019

Objectives: Many studies have been reported the efficacy of intravenous lipid emulsion (ILE) as an antidote on acute lipophilic drug toxicity. Clozapine, highly lipophilic dibenzodiazepine neuroleptics, is an important medication in the schizophrenia therapy regimen. Acute intoxication with antipsychotics is one of the main reasons for the referral of poisoned patients to the hospital. We expected that ILE could be used for the therapy of acute clozapine intoxicated patients. Methods: We used two groups of consisting of six male rats. Both groups received a toxic dose of clozapine (40 mg/kg) intravenously, via the tail vein. After 15 minutes, they were treated with intravenous infusion of 18.6 mg/kg normal saline (NS group), or 18.6 mg/kg ILE 20% (ILE group). We evaluated blood pressure (BP) and heart rate by power lab apparatus through the tail artery, ataxia by a rat rotary circle, seizure scores and death in multiple times after starting clozapine administration. For biochemical and pathological evaluations the samples of tissue and blood were taken. Results: Our results demonstrated that ILE 20% could return hypotension-induced clozapine better than normal saline. Furthermore, ataxia and seizure have rectified more rapidly and deaths reduced. Clozapine administration causes pancreatitis and lung injury but fat emulsion did not show an optimal effect on tissue damages caused by clozapine toxicity. Conclusion: In conclusion, ILE can remove toxic signs of clozapine same as other lipophilic medicines, however, clinical uses of ILE for this intention requires more appraisement to determine the precise implication and safety.

• 한국식품과학회지
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• 제41권2호
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• pp.203-209
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• 2009

본 연구는 톳유래의 무기성분강화염이 혈압과 무기질 대사에 미치는 영향을 검토하기 위하여 수행하였다. 실험처리는 고 저 염식군(Hizikia mineral salt)과 대조군(정제염)의 세가지 처리군으로 하였고, 실험동물인 본태성 고혈압쥐(SHR/NCrj)와 정상쥐(WKY/NCrj)에 음용수의 형태로 식염을 급여하였다. SHR에서는 시험 6주째 수축기혈압(SBP)이 C군보다 고 저염식군(A, B)이 각각 17,24 mmHg 낮았고, 기준혈압(RBP)대비 시험 6주째 혈압의 상승율은 A, B, C군에서 각각 12, 4, 21%로 B군이 가장 낮았다. WKY의 경우 시험 6주째 SBP는 A군과 C군에서 각각 165, 164 mmHg인 반면, B군은 148 mmHg로 훨씬 낮았다. RBP 대비 시험 6주째 혈압의 상승율은 A, B, C군에서 각각 17, 7, 19%로 B군이 가장 낮았다. 소변과 분변 중의 미네랄은 SHR/WKY 종에서 무기 성분강화염군이 정제염군보다 $Na^+$ 함량은 유의하게 낮았지만 $K^+$함량은 무기성분강화염군이 정제염군보다 유의하게 또는 대체로 높았다. 소변과 분변 중 미네랄함량은 다소간 차이가 있었지만 대변보다 소변으로 더 많이 배설된 것으로 나타났다. 간장의 경우 SHR은 $K^+$을 제외한 $Na^+$, $Ca^{++}$ 및 $Mg^{++}$ 함량은 무기성분강화 염군보다 대조군이 통계적으로 높았다(p<0.05). WKY에서 $Na^+$ 함량은 고염식군(A)이 가장 높았고, 신장에서 SHR의 $Na^+$ 함량은 정제염군이 무기성분강화염군보다 높았지만 WKY에서는 오히려 A군과 B군이 대조군보다 높았고, $K^+$ 함량은 저염식군(B)이 가장 높았다(p<0.05). 이상의 결과에서 톳유래의 저염식은 $Na^+$ 함량은 낮추고 $K^+$ 함량은 높이는 등의 체내 미네랄 대사에 긍정적인 영향을 미치기 때문에 혈압상승 억제작용이 있는 것으로 사료되었다.