• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2003.05a
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• pp.291-297
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• 2003

The aim of this research is to propose new framework for taxonomy of various business and its concept, due to the changes in market space. This framework is three-dimension cubic model, based on three concepts, business layer(BL), value chain(VC), and Real/Virtual(R/V) that symbolizes real environment and virtual(or cyber) space. And we showed that this framework is able to describe all expected(or existed) business types in certain industry by the combinations of BL-VC-R/V on three dimension. In addition, we suggested new definition of e-business and e-Logistics from view of BL-VC-R/V. In order to test availability, this framework was applied for logistics related business. and classified typical business types existed (or expected) in logistics area.

• Journal of Navigation and Port Research
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• v.27 no.4
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• pp.389-395
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• 2003

The aim of this research is to propose new framework for taxonomy of various business and its concept. due to the changes in market space. This framework is three-dimension cubic model based on three concepts, business layer(BL), value chain(VC), and Real/Virtual(R/V) that symbolizes real environment and virtual (or cyber) space. We showed that this framework is able to describe all expected(or existed) business types in certain industry by the combinations of BL-VC-R/V on three dimension. In addition, we suggested new definition of e-business and e-Logistics from view of BL-VC-R/V. In order to test availability of framework, this framework was applied for logistics related business, and we classified typical business types existed (or expected) in logistics area.

• Journal of Navigation and Port Research
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• v.28 no.1
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• pp.51-58
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• 2004

Due to the changes in market place, new business types(e.g. e-business} have been rapidly emerged and increased. However, those new business types have not much been emerged in port and logistics related industries, and adoption rate of e-business in this area is very low, compared to other industries. Thus, to promote e-business in this area, many policies have been studied. However, most of previous studies have not been based on industrial structure, and results of these studies have mostly been case by case. Further, there have been no research based on the related theories. As a result, despite many of research and project for shipping and port related e-business, prominent achievements in this area have never to be presented. For these reasons, it am be stated that, first of all, basic studies related to new business types in shipping and port are needed, and then, various policies based on results of those basic studies should be discussed. The aim of this study is to classify business types existed (or expected) in a port related industry, ship bunkering. This taxonomy was based on theories related to business layer(BL) and value chain(VC), and these BL and VC combination enabled to acquire all possible business types.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2003.05a
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• pp.298-303
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• 2003

Due to the changes in market place, new business types(e.g. e-business) have been rapidly emerged and increased. However, those new business types have not much been emerged n shipping and port related industries, and adoption rate of e-business in this area is very low, compared to other industries. Thus, to promote e-business in this area. many policies have been studied. However, most of previous studies have not been based on industrial structure, and results of these studies have mostly been case by case. Further, there have been no research based on the related theories. As a result, despite many of research and project for shipping and port related e-business, prominent achievements in this area have never to be presented. For these reasons, it can be stated that, first of all, basic studies related to new business types in shipping and port are needed. For these reasons, it can be stated that, first of all, basic studies related to new business types in shipping and port are needed, and then, various policies based on results of those basic studies should be discussed. The aim of this study is to classify business types existed (or expected) in a port related industry, ship bunkering. This taxonomy was based on theories related to business layer(BL) and value chain(VC), and these BL and VC combination enabled to acquire all possible business types.

• Journal of Korean society of Dental Hygiene
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• v.24 no.3
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• pp.219-227
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• 2024

Objectives: The pulp is the center of the tooth containing nerves and blood vessels. The condition in which the pulp becomes inflamed due to caries or periodontitis is called pulpitis. Pulpitis is a difficult-to-treat disease and causes peripheral nerve tissue changes and severe pain; however, the relationship between neuronal activity and voltage-gated sodium channel 1.7 (Nav1.7) expression in the trigeminal ganglion (TG) during pulpitis has not been well studied. In this study, we found that experimentally induced pulpitis activates Nav1.7 expression in the periphery, leading to neuronal overexpression in the TG. Thus, we sought to identify ways to regulate this process. Methods: Acute pulpitis was induced in rat maxillary molars by treating the pulp with allyl isothiocyanate (AITC). Three days later, in vivo optical imaging was used to record and compare neural activities in the TG. Western blotting was used to identify molecular changes in terms of the expression of extracellular signal-regulated kinase (ERK), c-Fos, transient receptor potential ankyrin 1 (TRPA1), and collapsin response mediator protein-2 (CRMP2) in the brain stem. Results: The results confirmed the neurological changes in the TGs of the pulpitis model, and histological and molecular biological evidence confirmed that increased Nav1.7 expression induced by pulpitis leads to pain. Furthermore, selective inhibition of Nav1.7 resulted in changes in neural activity, suggesting that pulpitis induces increased Nav1.7 expression, and that effective control of Nav1.7 could potentially reduce pain. Conclusions: The inhibition of overexpressed Nav1.7 channels may modulate nociceptive signal processing in the brain and effectively control pain associated with pulpitis.