• 한국임상수의학회지
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• 제12권1호
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• pp.789-798
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• 1995

우백혈병 바이러스감염 B 세포주(BL2M3 및 BL312)의 배양상층액에 대한 자기세포들의 증식반응을 검토하였다. 그 결과 BL2M3 및 BL312세포의 배양상층액을 자기세포인 BL2M3세포에 첨가했을 때 농도에 비례하여 현저한 증식을 유도하였다. 이것은 배양 4-5일차, 배양상층액의 첨가농도는 50-60%,세포수는 5x$10^4$-5x$10^{5}$ /ml에서 최적의 증식반응을 보였다. 우태아혈청(FBS) 무첨가 BL2M3 및 BL312세포의 배양상층액에 대해서도 BL2M3세포는 동일한 증식반응을 보였다. 한편 BL2M3 및 BL312세포의 배양상층액을 BL312세포에 첨가했을 때는 BL2M3세포의 경우에 비해 현저하지 않았다. 또한 BL2M3 및 BL312세포의 배양상층액은 말초혈액 림프구에 대해서도 pokeweed mitogen(PWM)첨가 유무에 관계없이 증식을 유도하였다. 그러나 PWM자극 말초혈액 단핵세포의 배양상층액은 BL2M3 및 BL312세포에 대해서 전혀 증식을 유도하지 못했다. 이상의 결과로부터 우백혈병 바이러스감염 B세포주 특히 BL2M3세포는 세포자신이 증식인자를 분비하고 그것과 반응하여 증식하는 소위 autocrine growth 양상을 보이는 것으로 판명되었다.

• Journal of Oral Medicine and Pain
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• 제8권1호
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• pp.121-126
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• 1983

This study is conducted with a view to make correct sexual differentiation by the utilization of discriminant functions. For that purpose were randomly sampled out 148 young adults testes, comprising 67 males and 81 females, ranging from 15 through 18 years fo age. Based on the values made available from the measurement of 6 items corresponding to the maxillary cast models, a statistical analysis was made to abstract feasible discriminant functions. The results findings are as follows: 1. The mean value by sex indicates, in all items, higher one in male group than in female group. 2. Through the measurement were defined as singnificant items in sexual differentiation the bucco-lingual dimensions of canine, 1st-molar, 2nd molar, and 1st bimolat width. 3. Derived from the value from measurement items were discriminant functions with the intention of applying them to sexual differentiation, as follows: 1) Y=-25.4112+0.7513BL3+0.3298BL4-0.2854BL5+0.7350BL6-0.3482BL7+0.2893AW (as tested by Method I) 2)Y=-25.0628+0.7737BL3+0.7468BL6-0.3885BL5+0.2951AW(as tested by Method II) BL3 : Bucco-lingual dimension of upper canine BL4 : Bucco-lingual dimension of upper first prmolar BL5 : Bucco-lingual dimension of upper second premolar BL5 : Bucco-lingual dimension of upper first molar BL6 : Bucco-lingual dimension of upper second molar AW : Upper first bimolar width 4. Sexual defferentiation in terms of descriminant functions represented a probility of 74.6%.

• 수산해양기술연구
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• 제20권1호
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• pp.17-22
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• 1984

시각막의 바탕과 줄무늬 색상을 흑색, 청색, 적색, 백색과 황색 중 2가지씩 순열시킨 20가지 경우에 대하여 붕어 Carassius carassius와 금붕어 Carassius auratus의 시각운동반응을 조사한 결과는 다음과 같다. 1. 붕어의 시각운동반응율은 적색-흑색, 청색-황색과 백색-흑색 일 때 80~90%로 높았으며, 황색-백색, 백색-황색, 흑색-청색, 청색-흑색과 적색-백색일 때 25~40%로 낮았다. 2. 금붕어의 시각운동반응율은 백색-황색, 청색-흑색과 백색-적색을 제외하고는 80%이상으로 높았었다. 3. 붕어의 3분 동안의 평균선 회수는 황색-청색, 백색-청색, 황색-흑색과 백색-흑색일 때 7.5~9.5회로 많았으며, 청색-적색, 황색-백색, 흑색-청색, 적색-모든 색과 청색-흑색일 때 1.8~3.9회로 적었다. 4. 금붕어의 3분 동안의 평균선 회수는 황색-청색, 백색-청색과 백색-흑색일 때만 4.1~4.9회이고, 나머지는 1.6~3.5회로 적었다

• 한국임상수의학회지
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• 제22권3호
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• pp.202-205
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• 2005

본 연구는 개에서 위수혈(BL-21) 및 중완혈(CV-12)에 대한 지침의 구토억제효과를 규명할 목적으로 수행하였다. 사용 혈위는 BL-21 및 CV-12이었다. 각 군에서 구토 유발을 위하여 $2{\%}$ xylazine(2.2 mg/kg)을 투여하였으며, metoclopramide 수침은 1 mg/kg의 비율로 해당 혈위에 각각 수침하였다 대조군 및 실험군에 있어서 xylazine 투여 20분전에 BL-21 및 CV-12에 자침, metoclopramide 수침 및 뜸 처치를 각각 실시하였다. 대조군 및 실험군에서 구토율 및 구토발현시간을 각각 조사한 결과는 다음과 같았다. BL-21자침군, CV-12 자침군 및 BL-21과 CV-12 병용 자침군의 구토율은 각각 $33.3{\%}\;50.0{\%}$ 및 $33.3{\%}$로서 대조군($66.7{\%}$)보다 낮았다. BL-21 자침군, CV-12 자침군 및 BL-21과 CV-12 병용 자침군에 있어서 구토 발현 시간은 대조군과 유사하였다. BL-21 수침군 및 CV-12 수침군의 구토 억제율은 각각 $100{\%}$ 및 $83.6{\%}$로서 수침군의 대조군($63.6{\%}$)보다 높았다. 구토발현시간은 수침군의 BL-21 수침군은 0분이었으며, CV-12 수침군은 5분으로서 수침군의 대조군과 유사하였다. BL-21 뜸 처치군 및 CV-12뜸 처치군의 구토율은 각각 $33.3{\%}$로서 뜸 처치군의 대조군($66.7{\%}$)보다 낮았다. 구토발현시간은 뜸 처치군의 대조군 $2{\~}4$분, BL-21 뜸 처치군이 $2{\~}4$분 및 CV-12 뜸 처치군이 $2{\~}3$분으로서 큰 차이를 나타내지 않았다. 이상의 결과를 종합해 볼 때, 개에서 $2{\%}$ xylazine 투여로 유발된 구토에 대한 BL-21 및 CV-12의 자침, metoclopramide 수침 및 뜸 처치가 각각 구토 억제에 효과적이었으며, 또한 이들 중 BL-21에 대한 metoclopramide 수침의 구토억제 효과가 가장 우수하였다.

• 디지털산업정보학회논문지
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• 제13권3호
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• pp.105-113
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• 2017

Considered as the "new normal" mode of learning, BL has become popular in recent years especially in University education. BL is defined as a learning approach that combines e-learning and face-to-face classroom learning. BL allows for more interactive and reflective learning environment resulting in enhancing learner-directed learning. The adoption of BL in university has made it significant to probe the crucial determinants that would entice instructors and learners to use BL and enhance learning satisfaction. The primary purpose of this study is to investigate the affecting factors of the satisfaction of BL in universities in terms of leaner's aspects. Learner's role is very important in BL, because learner should self-directed study for effective performance and satisfaction in BL environment. Based on prior studies motivation, self-efficacy, and educational expectancy were identified as affecting factors of satisfaction in BL. According to the result of multiple regression, all factors(motivation, self-efficacy, and educational expectancy) were found to be significantly related to the learner's satisfaction in BL. It can provide practical guideline on effective operation strategy for BL in universities.

• Journal of Photoscience
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• 제9권2호
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• pp.335-337
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• 2002

Blue light (BL) induces stomatal opening through activation of H$^{+}$ pump, which creates electrical gradient across the plasma membrane for $K^{+}$ uptake into guard cells. The pump is the plasma membrane H$^{+}$ -ATPase and is activated via phosphorylation of the C-terminus with concomitant binding of the 14-3-3 protein. The opening is initiated by the perception of BL through phototropin (phot), which are recently identified as BL receptors in stomatal guard cells. In this study, we provide the biochemical evidence for phots as BL receptors in stomatal guard cells. vfphot was phosphorylated reversibly by BL, and phosphorylation levels of vfphot increased earlier than those of the plasma membrane W-ATPase. BL-dependent phosphorylations of vfphot and H$^{+}$-ATPase showed similar fluence dependency. Staurosporin, an inhibitor of serine/threonine protein kinase, and diphenyleneiodonium chloride (DPI), an inhibitor of flavoprotein, inhibited BL-dependent phosphorylations of vfphot and H$^{+}$ -ATPase. These results indicate that vfphot acts as a BL-receptor mediating stomatal opening.l opening.

• Journal of Acupuncture Research
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• 제27권5호
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• pp.13-24
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• 2010

Objectives : This study was designed to investigate the effects of bee venom acupuncture at Shinsu($BL_{23}$) and Daejangsu($BL_{25}$) on neuropathic pain induced by tibial and sural nerve injury in rats. Methods : Neuropathic pain model was made by partial resection of tibial and sural nerve. Three weeks after the neuropathic surgery, bee venom acupuncture was firstly injected at $BL_{23}$ and $BL_{25}$, then we measured withdrawal responses induced by von Frey filament and acetone stimulation. Bee venom acupunctures were injected 6times on every 2days. Measurement of withdrawal responses were conducted on the same days. After bee venom acupuncture injection, expression levels of c-Fos, nocieptin and KOR-3 were observed through using immunohistochemistry. Results : In this experiment, bee venom acupunctures at $BL_{23}$ and $BL_{25}$ decreased levels of withdrawal responses induced by von Frey filament and acetone stimulation respectively. In addtion, expression levels of c-Fos, nociceptin and KOR-3 in central gray part of brain in rats were decreased by bee venom acupuncture. Conclusions : These results imply that bee venom acupuncture was useful to treat patients with neuropathic pain, and related mechanisms were involved in opioid and their receptors such as nociceptin and KOR-3.

• 대한건축학회논문집:계획계
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• 제34권3호
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• pp.61-72
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• 2018

This study pursued to obtain 3 consecutive purposes. First, a conceptual model for comparing 3 constructivist teaching and learning strategies( problem-based learning[$P_bBL$], case-based learning[CBL] and project-based learning[$P_jBL$]) was developed. Relationships of these constructivist strategies with the development of expertise for learners were discussed. Second, specific differences between $P_bBL$, CBL and $P_jBL$ as applied in architectural design courses were analyzed under each of the teaching and learning category. Some analytical indexes were developed by content analysis, which are applicable effectively to reveal the differences. Based on the previous findings, third, a set of strategic guidelines for use in class were made and suggested in order to develop and improve expertise in architectural design. These guidelines were largely targeted for university design courses as well as education or reeducation of practicing architects. Expecially, combined application of $P_bBL$, CBL and $P_jBL$ was hypothesized and suggested as class management guidelines. In sum, a variety of $P_bBL$ problems, CBL cases and $P_jBL$ projects should be developed for expecting audience based on design subjects and tasks. As working domains of practicing architects, exploring/analyzing, understanding/making applications, and criticizing/self-reflecting should be considered in the development process.

• 한국자연치유학회지
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• 제10권1호
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• pp.26-32
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• 2021

목적: 경혈 지압에서 모든 혈의 가압 방향은 통상적으로 수직 방향이다. 그러나 지실혈(BL52)에서는 수직 방향이 배꼽 부위를 향하는지 몸통의 중심을 향하는지 명확하지 않다. 본 연구에서는 30명의 대상자의 BL52에 대한 지압의 방향에 따른 압통 역치를 측정하여 효과적인 지압 방향을 연구하는 것이었다. 방법: 대상자의 명문혈(GV4)을 중심으로 좌우 지실혈까지의 거리와 GV4와 배꼽까지의 거리를 측정하여 명문혈 좌우 지실혈이 배꼽을 지나는 타원을 이용하여 좌우 지실혈에서 배꼽 방향 및 몸통 중심 방향의 각도를 계산했다. BL52에 두 방향으로 가압하면서 대상자들이 통증을 느끼는 시점의 압력을 통증 역치로 하였다. 압통역치는 대상자의 좌우 BL52에서 3분 간격으로 3번씩 측정하였다. 결과: 대상자들의 좌우 BL52에서 측정된 압통 역치는 몸통 중심부를 향하여 가압할 때 상대적으로 유의하게 감소하였다(p < .05). BL52에서는가압방향이몸통의중심부를향할때압력에대해더예민한것으로나타났다. 결론: 주변보다 외부 자극에 더 예민한 경혈의 지압 요법에서, BL52에서는 몸통의 중심부를 향하도록 지압하는 것이 배꼽 방향으로 지압하는 것보다 효율적이라는 것을 시사한다.

• Journal of Magnetics
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• 제21권3호
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• pp.399-404
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• 2016

This paper presents a new permanent magnet (PM) assisted topology for a recently introduced brushless wound rotor synchronous machine (BL-WRSM) [1]. The BL-WRSM had a dual-inverter configuration for generating a composite magneto motive force (MMF) with a fundamental component and a subharmonic component. The subharmonic component of the MMF is used for brushless excitation of the rotor. In this paper, additional PMs were introduced on the rotor of the BL-WRSM, making it a hybrid BL-WRSM. We also discussed the flux weakening operation for the hybrid BL-WRSM. The hybrid BL-WRSM offered advantages for starting the machine and provided better performance under full-load conditions. The finite element method (FEM) was used to analyze the performance of the hybrid BL-WRSM, and we compared its performance with BL-WRSM. Finally, prototypes were built with and without the PM-assistance, and experiments were conducted to demonstrate their performance.