• Journal of Veterinary Clinics
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• v.12 no.1
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• pp.789-798
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• 1995

우백혈병 바이러스감염 B 세포주(BL2M3 및 BL312)의 배양상층액에 대한 자기세포들의 증식반응을 검토하였다. 그 결과 BL2M3 및 BL312세포의 배양상층액을 자기세포인 BL2M3세포에 첨가했을 때 농도에 비례하여 현저한 증식을 유도하였다. 이것은 배양 4-5일차, 배양상층액의 첨가농도는 50-60%,세포수는 5x$10^4$-5x$10^{5}$ /ml에서 최적의 증식반응을 보였다. 우태아혈청(FBS) 무첨가 BL2M3 및 BL312세포의 배양상층액에 대해서도 BL2M3세포는 동일한 증식반응을 보였다. 한편 BL2M3 및 BL312세포의 배양상층액을 BL312세포에 첨가했을 때는 BL2M3세포의 경우에 비해 현저하지 않았다. 또한 BL2M3 및 BL312세포의 배양상층액은 말초혈액 림프구에 대해서도 pokeweed mitogen(PWM)첨가 유무에 관계없이 증식을 유도하였다. 그러나 PWM자극 말초혈액 단핵세포의 배양상층액은 BL2M3 및 BL312세포에 대해서 전혀 증식을 유도하지 못했다. 이상의 결과로부터 우백혈병 바이러스감염 B세포주 특히 BL2M3세포는 세포자신이 증식인자를 분비하고 그것과 반응하여 증식하는 소위 autocrine growth 양상을 보이는 것으로 판명되었다.

• Journal of Oral Medicine and Pain
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• v.8 no.1
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• pp.121-126
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• 1983

This study is conducted with a view to make correct sexual differentiation by the utilization of discriminant functions. For that purpose were randomly sampled out 148 young adults testes, comprising 67 males and 81 females, ranging from 15 through 18 years fo age. Based on the values made available from the measurement of 6 items corresponding to the maxillary cast models, a statistical analysis was made to abstract feasible discriminant functions. The results findings are as follows: 1. The mean value by sex indicates, in all items, higher one in male group than in female group. 2. Through the measurement were defined as singnificant items in sexual differentiation the bucco-lingual dimensions of canine, 1st-molar, 2nd molar, and 1st bimolat width. 3. Derived from the value from measurement items were discriminant functions with the intention of applying them to sexual differentiation, as follows: 1) Y=-25.4112+0.7513BL3+0.3298BL4-0.2854BL5+0.7350BL6-0.3482BL7+0.2893AW (as tested by Method I) 2)Y=-25.0628+0.7737BL3+0.7468BL6-0.3885BL5+0.2951AW(as tested by Method II) BL3 : Bucco-lingual dimension of upper canine BL4 : Bucco-lingual dimension of upper first prmolar BL5 : Bucco-lingual dimension of upper second premolar BL5 : Bucco-lingual dimension of upper first molar BL6 : Bucco-lingual dimension of upper second molar AW : Upper first bimolar width 4. Sexual defferentiation in terms of descriminant functions represented a probility of 74.6%.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.20 no.1
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• pp.17-22
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• 1984

The author carried out an experiment to find on the optomotor response of crusian carp, Carassius carassius and goldfish, Carassius auratus in accordance with the colors of the wall and the stripes labeled on the revolving visual screen. The results are as follows; 1. The optomotor response rate of crusian carp was 80% or more in case of B-Y, R-Bl and W-Bl pair of colors, and 50% or less in case of Bl-B, B-Bl, R-W, R-Y, W-Y and Y-W pair. 2. The optomotor response rate of goldfish was 80% or more in all except B-Bl, W-R and W-Y pair. 3. Mean round number of crusian carp was 7.5-9.5 revolutions in case of W-Bl, Y-Bl, W-B and Y-B pair, and 1.8-3.9 revolutions in case of Bl-B, Bl-Y, B-Bl, B-R, R-All and Y-W pair for 3 minutes. 4. Mean rounded number of goldfish was only 4.1-4.9 revolutions in case of W-Bl, W-B and Y-B pair for 3 minutes.

• Journal of Veterinary Clinics
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• v.22 no.3
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• pp.202-205
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• 2005

The present study was made in order to clarify the anti-emetic effect by needle-acupuncture (AP), injection-AP and moxibustion in xylazine - induced vomiting of dogs. Twelve mongrel dogs (4 months to 5 year old, 2 to 4 kg of body weight), eleven mongrel dogs (4 months to 5 years old, 2 to 10 kg of body weight) and twelve mongrel dogs (4 months to 1 year old, 2 to 4 kg of body weight) were used for clarification of anti-emetic effect by needle-AP, injection-AP and moxibustion, respectively. The experimental animals were devided into control(6 heads), BL-21(6 heads), CV-12(6 heads) and BL-21+CV-12(6 heads) groups using total 6 dogs with vomiting selected in preliminary experiment, respectively in needle-AP treatment. In addition, the experimental dogs were divided into control (11 heads), BL-21 (6 heads) and CV-12(6 heads) groups using 11 dogs, respectively in injection-AP treatment. In moxibustion treatment the experimental dogs were divided into control (6 heads), BL-21(6 heads) and CV-12(6 heads) groups using 6 dogs, respectively. Five days after the experiment of one group was finished, the other group was examined in each experiment. Acupuncture needle was maintained for 20 minutes in needle-AP treatment. Metoclopramide was used in injection-AP treatment. Commercial moxa was used in moxibustion treatment. Vomiting was induced by intramuscular injection with $2{\%}$ xylazine 20 minutes after treatments of needle-AP, injection-AP and moxibustion, respectively. The vomiting rates of BL-21($33.3{\%}$), CV-12($50{\%}$) and BL-21+CV-12($33.3{\%}$) were lower than that of control($66.7{\%}$) and vomiting times of experimental groups were similar to that of control in needle-AP treatment. The vomiting rates of BL-21 ($0{\%}$) and CV-12($16.4{\%}$) were lower than that of control($66.7{\%}$) and the vomiting time of CV-12 group was similar to that of control group in injection-AP treatment. The vomiting rates of BL-21($33.3{\%}$) and CV-12($33.3{\%}$) were lower than that of control ($66.7{\%}$) and vomiting times of experimental group were similar to that of control group in moxibustion treatment. In conclusion, it was considered that needle-AP, metoclopramide injection-AP and moxibustion at BL-21 and CV-12 were effective for anti-emesis in xylazine induced vomiting of dogs and metoclopramide injection-AP was the most effective method for anti-emesis among them.

• Journal of Korea Society of Digital Industry and Information Management
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• v.13 no.3
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• pp.105-113
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• 2017

Considered as the "new normal" mode of learning, BL has become popular in recent years especially in University education. BL is defined as a learning approach that combines e-learning and face-to-face classroom learning. BL allows for more interactive and reflective learning environment resulting in enhancing learner-directed learning. The adoption of BL in university has made it significant to probe the crucial determinants that would entice instructors and learners to use BL and enhance learning satisfaction. The primary purpose of this study is to investigate the affecting factors of the satisfaction of BL in universities in terms of leaner's aspects. Learner's role is very important in BL, because learner should self-directed study for effective performance and satisfaction in BL environment. Based on prior studies motivation, self-efficacy, and educational expectancy were identified as affecting factors of satisfaction in BL. According to the result of multiple regression, all factors(motivation, self-efficacy, and educational expectancy) were found to be significantly related to the learner's satisfaction in BL. It can provide practical guideline on effective operation strategy for BL in universities.

• Journal of Photoscience
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• v.9 no.2
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• pp.335-337
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• 2002

Blue light (BL) induces stomatal opening through activation of H$^{+}$ pump, which creates electrical gradient across the plasma membrane for $K^{+}$ uptake into guard cells. The pump is the plasma membrane H$^{+}$ -ATPase and is activated via phosphorylation of the C-terminus with concomitant binding of the 14-3-3 protein. The opening is initiated by the perception of BL through phototropin (phot), which are recently identified as BL receptors in stomatal guard cells. In this study, we provide the biochemical evidence for phots as BL receptors in stomatal guard cells. vfphot was phosphorylated reversibly by BL, and phosphorylation levels of vfphot increased earlier than those of the plasma membrane W-ATPase. BL-dependent phosphorylations of vfphot and H$^{+}$-ATPase showed similar fluence dependency. Staurosporin, an inhibitor of serine/threonine protein kinase, and diphenyleneiodonium chloride (DPI), an inhibitor of flavoprotein, inhibited BL-dependent phosphorylations of vfphot and H$^{+}$ -ATPase. These results indicate that vfphot acts as a BL-receptor mediating stomatal opening.l opening.

• Journal of Acupuncture Research
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• v.27 no.5
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• pp.13-24
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• 2010

Objectives : This study was designed to investigate the effects of bee venom acupuncture at Shinsu($BL_{23}$) and Daejangsu($BL_{25}$) on neuropathic pain induced by tibial and sural nerve injury in rats. Methods : Neuropathic pain model was made by partial resection of tibial and sural nerve. Three weeks after the neuropathic surgery, bee venom acupuncture was firstly injected at $BL_{23}$ and $BL_{25}$, then we measured withdrawal responses induced by von Frey filament and acetone stimulation. Bee venom acupunctures were injected 6times on every 2days. Measurement of withdrawal responses were conducted on the same days. After bee venom acupuncture injection, expression levels of c-Fos, nocieptin and KOR-3 were observed through using immunohistochemistry. Results : In this experiment, bee venom acupunctures at $BL_{23}$ and $BL_{25}$ decreased levels of withdrawal responses induced by von Frey filament and acetone stimulation respectively. In addtion, expression levels of c-Fos, nociceptin and KOR-3 in central gray part of brain in rats were decreased by bee venom acupuncture. Conclusions : These results imply that bee venom acupuncture was useful to treat patients with neuropathic pain, and related mechanisms were involved in opioid and their receptors such as nociceptin and KOR-3.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.34 no.3
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• pp.61-72
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• 2018

This study pursued to obtain 3 consecutive purposes. First, a conceptual model for comparing 3 constructivist teaching and learning strategies( problem-based learning[$P_bBL$], case-based learning[CBL] and project-based learning[$P_jBL$]) was developed. Relationships of these constructivist strategies with the development of expertise for learners were discussed. Second, specific differences between $P_bBL$, CBL and $P_jBL$ as applied in architectural design courses were analyzed under each of the teaching and learning category. Some analytical indexes were developed by content analysis, which are applicable effectively to reveal the differences. Based on the previous findings, third, a set of strategic guidelines for use in class were made and suggested in order to develop and improve expertise in architectural design. These guidelines were largely targeted for university design courses as well as education or reeducation of practicing architects. Expecially, combined application of $P_bBL$, CBL and $P_jBL$ was hypothesized and suggested as class management guidelines. In sum, a variety of $P_bBL$ problems, CBL cases and $P_jBL$ projects should be developed for expecting audience based on design subjects and tasks. As working domains of practicing architects, exploring/analyzing, understanding/making applications, and criticizing/self-reflecting should be considered in the development process.

• Journal of Naturopathy
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• v.10 no.1
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• pp.26-32
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• 2021

Purpose: At acupoint pressure, the pressing direction of all acupoints is usually vertical. However, it is not clear whether the vertical direction is toward the belly button or the body's center in the BL52. In this study, the effective direction of acupressure was studied by measuring the pressure pain threshold according to the direction of acupressure in 30 subjects. Methods: The distance from the subject's GV4 to the left and right BL52 and the distance from GV4 to the navel were measured, and then using the ellipse where the left and right BL52 of GV4 pass through the navel, the angles of the navel direction and the body's center were calculated in the left and right BL52. The pressure at the time when the subjects felt pain while pressing the BL52 in two directions was used as the acupressure pain threshold. The pain threshold was measured 3 times at 3 minute intervals on the left and right BL52s of the subject. Results: The acupressure pain threshold measured in the left and right BL52 of the subjects was significantly decreased when pressed toward the trunk center (p < .05). In BL52, it was more sensitive to pressure when the direction of pressure is toward the body's center. Conclusions: Acupressure therapy of acupoint is more sensitive to external stimuli than the surrounding. In this study, acupressure directed toward the trunk center is more efficient than toward the belly button in BL52.

• Journal of Magnetics
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• v.21 no.3
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• pp.399-404
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• 2016

This paper presents a new permanent magnet (PM) assisted topology for a recently introduced brushless wound rotor synchronous machine (BL-WRSM) [1]. The BL-WRSM had a dual-inverter configuration for generating a composite magneto motive force (MMF) with a fundamental component and a subharmonic component. The subharmonic component of the MMF is used for brushless excitation of the rotor. In this paper, additional PMs were introduced on the rotor of the BL-WRSM, making it a hybrid BL-WRSM. We also discussed the flux weakening operation for the hybrid BL-WRSM. The hybrid BL-WRSM offered advantages for starting the machine and provided better performance under full-load conditions. The finite element method (FEM) was used to analyze the performance of the hybrid BL-WRSM, and we compared its performance with BL-WRSM. Finally, prototypes were built with and without the PM-assistance, and experiments were conducted to demonstrate their performance.