• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.2
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• pp.481-485
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• 2003

Experimental studies were done to research the clinical effects of Juglandis Semen aqua-acupuncture and acupuncture(BL13, BL17, BL13ㆍ17 and free points) on the anti-allergic inflammation response. The following results have been obtained ; JSAA was increased in the lymphocyte proliferation in cultured murine thymocytes and splenocytes. The production of IL-1β was decreased in Juglandis Semen aqua-acupuncture and acupuncture(BL13, BL17 and BL13ㆍ17) group. The production of IL-4 was decreased in Juglandis Semen aqua-acupuncture and acupuncture(BL13, BL17 and BL13ㆍ17) group. The production of total IgG was decreased in Juglandis Semen aqua-acupuncture(BL13 and BL13ㆍ17) and acupuncture(BL13, BL17 and BL13ㆍ17) group. According to the above results, Semen aqua-acupuncture and acupuncture(BL13, BL17 and BL13ㆍ17) both enhances the specific immune response in T and B cells and depress the allergic inflammation reaction.

• Journal of Veterinary Clinics
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• v.12 no.1
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• pp.789-798
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• 1995

우백혈병 바이러스감염 B 세포주(BL2M3 및 BL312)의 배양상층액에 대한 자기세포들의 증식반응을 검토하였다. 그 결과 BL2M3 및 BL312세포의 배양상층액을 자기세포인 BL2M3세포에 첨가했을 때 농도에 비례하여 현저한 증식을 유도하였다. 이것은 배양 4-5일차, 배양상층액의 첨가농도는 50-60%,세포수는 5x$10^4$-5x$10^{5}$ /ml에서 최적의 증식반응을 보였다. 우태아혈청(FBS) 무첨가 BL2M3 및 BL312세포의 배양상층액에 대해서도 BL2M3세포는 동일한 증식반응을 보였다. 한편 BL2M3 및 BL312세포의 배양상층액을 BL312세포에 첨가했을 때는 BL2M3세포의 경우에 비해 현저하지 않았다. 또한 BL2M3 및 BL312세포의 배양상층액은 말초혈액 림프구에 대해서도 pokeweed mitogen(PWM)첨가 유무에 관계없이 증식을 유도하였다. 그러나 PWM자극 말초혈액 단핵세포의 배양상층액은 BL2M3 및 BL312세포에 대해서 전혀 증식을 유도하지 못했다. 이상의 결과로부터 우백혈병 바이러스감염 B세포주 특히 BL2M3세포는 세포자신이 증식인자를 분비하고 그것과 반응하여 증식하는 소위 autocrine growth 양상을 보이는 것으로 판명되었다.

• Communications of the Korean Mathematical Society
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• v.19 no.2
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• pp.219-232
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• 2004

We study relationships between closure operators and BL-algebras. We investigate the properties of closure operators and BL-homomorphisms on BL-algebras. We show that the image of a closure operator on a BL-algebra is isomorphic to a quotient BL-algebra.

• Korean Journal of Veterinary Research
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• v.47 no.4
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• pp.469-473
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• 2007

This study was performed to investigate the effects of urinary acupoint (BL-23, BL-28) by acupuncture (AP) and electroacupuncture (EA) on urinary bladder in dogs. Four healthy male dogs aged within the range of 6~8 months were used in this experiment. For Electrodes implantation on the bladder, dogs were to undergo surgical operation. The purpose of investigating the effect on urinary bladder was to evaluate electromyogram (EMG) changes according to AP or EA at Shen Shu (BL-23), Pang Guang Shu (BL-28) and non-acupoint. AP and EA (2~4 V, 10 Hz) were applied for 20 min to each point. EMG was evaluated when acupuncture began stimulation and as soon as the stimulation by electroacupuncture was gone. By the experiment of investigating the effect of urinary time it was estimated to measure time up to urination from stimulation on effective acupoint, after saline was filled with 70% of whole volumes on urinary bladder. The wave of EMG on resting stage showed simple and regular, whereas that of EMG on urination showed irregularly strong peaks before urination. Acupuncture of BL-28 had an influence on changes of EMG which had irregular peaks on urination. But the changes of EMG after acupuncture of BL-28 and control were regular like resting stage. The changes of EMG after EA at BL-23 and BL-28 showed irregularly a variety of wave forms. The interval through urination from stimulation at BL-28 and control become short as measuring time by EA (p<0.01). According to the results, AP at BL-28 was effective to urinary bladder. EA at BL-23 and BL-28 was effective to urinary bladder. Especially, the interval on stimulating at BL-28 by EA was the shortest in measuring time to urination from stimulation.

• Journal of Oral Medicine and Pain
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• v.8 no.1
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• pp.121-126
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• 1983

This study is conducted with a view to make correct sexual differentiation by the utilization of discriminant functions. For that purpose were randomly sampled out 148 young adults testes, comprising 67 males and 81 females, ranging from 15 through 18 years fo age. Based on the values made available from the measurement of 6 items corresponding to the maxillary cast models, a statistical analysis was made to abstract feasible discriminant functions. The results findings are as follows: 1. The mean value by sex indicates, in all items, higher one in male group than in female group. 2. Through the measurement were defined as singnificant items in sexual differentiation the bucco-lingual dimensions of canine, 1st-molar, 2nd molar, and 1st bimolat width. 3. Derived from the value from measurement items were discriminant functions with the intention of applying them to sexual differentiation, as follows: 1) Y=-25.4112+0.7513BL3+0.3298BL4-0.2854BL5+0.7350BL6-0.3482BL7+0.2893AW (as tested by Method I) 2)Y=-25.0628+0.7737BL3+0.7468BL6-0.3885BL5+0.2951AW(as tested by Method II) BL3 : Bucco-lingual dimension of upper canine BL4 : Bucco-lingual dimension of upper first prmolar BL5 : Bucco-lingual dimension of upper second premolar BL5 : Bucco-lingual dimension of upper first molar BL6 : Bucco-lingual dimension of upper second molar AW : Upper first bimolar width 4. Sexual defferentiation in terms of descriminant functions represented a probility of 74.6%.

• Honam Mathematical Journal
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• v.44 no.2
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• pp.165-178
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• 2022

In this paper, Sheffer stroke BL-algebra and its properties are investigated. It is shown that a Cartesian product of two Sheffer stroke BL-algebras is a Sheffer stroke BL-algebra. After describing a filter of Sheffer stroke BL-algebra, a congruence relation on a Sheffer stroke BL-algebra is defined via its filter, and quotient of a Sheffer stroke BL-algebra is constructed via a congruence relation. Also, it is defined a homomorphism between Sheffer stroke BL-algebras and is presented its properties. Thus, it is stated that the class of Sheffer stroke BL-algebras forms a variety.

• Microbiology and Biotechnology Letters
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• v.23 no.2
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• pp.164-169
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• 1995

An endogenous cryptic plasmid, pBL1, which has been used to construct plasmid vectors for coryneform bacteria producing amino acids, was eliminated from Brevibacterium lactofermentum. The pBL1 was partially digested with Sau3AI and the resulting DNA fragments were subcloned into a suicide vector pEM1 which contains a kanamycin-resistant (km$^{r}$) gene. KM$^{r}$ B. lactofermentum transconjugants were obtained by conjugal transfer of the pEM1 derivatives containing pBL1 DNA fragments from Escherichia coli into B. lactofermentum. A km$^{r}$ transconjugant was analyzed to contain a plasmid pEB14, which occurred in vivo by homologous recombination between pBL1 and the conjugal-transferred plasmid. The pEB14 including the pEM1-derived km$^{r}$ gene was found to be lost concomitantly with km$^{r}$ phenotype, resulting in the construction of a pBL1-free strain of B lactofermentum. Based on transformation efficiencies and plasmid stability, the resultant pBL1- free strain is more useful than wild strain as a host cell for genetic manipulation. It could be concluded that foreign plasmid DNAs are efficiently isolated and analyzed from the pBL1-free strain because of the absence of endogenous pBL1 plasmid.

• Journal of Acupuncture Research
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• v.20 no.4
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• pp.180-191
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• 2003

Objective & Methods : Experimental studies were done to research the clinical effects of Juglandis Semen aqua-acupuncture and acupuncture($BL_{13}{\cdot}BL_{17}$) on the anti-allergic response. anaphylaxis provoked by the compound48/80, delayed type hypersensitivity response to picryl chloride and SRBC and inflammation response to egg albumin. Results : The following results have been obtained; 1. Juglandis Semen aqua-acupuncture and acupuncture($BL_{13}{\cdot}BL_{17}$) group were increased the survival rate in compound 48/80 induced systemic anaphylactic reaction. 2. Picryl chloride induced contact dermatitis and delayed type hypersensitivity in SRBC challenged mouse were significantly decreased in Juglandis Semen aqua-acupuncture and acupuncture($BL_{13}{\cdot}BL_{17}$) group. 3. Inflammation response-WBC, CRP and Nitric Oxide in egg albumin induced allergic rat were significantly decreased in Juglandis Semen aqua-acupuncture and acupuncture($BL_{13}{\cdot}BL_{17}$) group. Conclusions : According to the above results, Semen aqua-acupuncture and acupuncture($BL_{13}{\cdot}BL_{17}$) both depress the allergy reaction.

• Journal of Korea Society of Digital Industry and Information Management
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• v.13 no.3
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• pp.105-113
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• 2017

Considered as the "new normal" mode of learning, BL has become popular in recent years especially in University education. BL is defined as a learning approach that combines e-learning and face-to-face classroom learning. BL allows for more interactive and reflective learning environment resulting in enhancing learner-directed learning. The adoption of BL in university has made it significant to probe the crucial determinants that would entice instructors and learners to use BL and enhance learning satisfaction. The primary purpose of this study is to investigate the affecting factors of the satisfaction of BL in universities in terms of leaner's aspects. Learner's role is very important in BL, because learner should self-directed study for effective performance and satisfaction in BL environment. Based on prior studies motivation, self-efficacy, and educational expectancy were identified as affecting factors of satisfaction in BL. According to the result of multiple regression, all factors(motivation, self-efficacy, and educational expectancy) were found to be significantly related to the learner's satisfaction in BL. It can provide practical guideline on effective operation strategy for BL in universities.

• Journal of the Korean Institute of Intelligent Systems
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• v.11 no.3
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• pp.286-291
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• 2001

We inverstigate the properties of BL-hommorphisms on BL-algebras. In particular, we find the BL-algebra in duced by lattice-isomorphism. From these facts, we obtain the generalized Lukasiewicz structure. More-over, we study the properties of quotient BL-algebras and deductive systems.